Unexpected Elements

On 18th February the Perseverance rover should land on Mars. Katie Stack-Morgan of NASA’s Jet Propulsion Lab tells Roland Pease about the technological advances that mean that the spacecraft should be able to land in Jezero Crater. Imperial College geologist Sanjeev Gupta discusses what this crater can reveal about the history of life on the red planet. After months of negotiations, and weeks of work on the ground, a team brought together by the World Health Organisation has just concluded its first attempts to find out the origins of SARS-Cov2 in Wuhan. Peter Daszak, who has worked closely with Chinese virologists in the past, briefed Roland Pease on what had been discovered. The South African government has announced that it will not be rolling out the Astra Zeneca Covid vaccine as it appears it is not very effective against the dominant strain in the country. Helen Rees, of Witwatersrand University and a member of South Africa’s Health Products Regulatory Authority, explains that the ‘ban’ is an overstatement.At least 35 people died in a flood disaster in the Himalayan state of Uttarakhand in India on February 6th. The details are still unclear, but the trigger seems to be associated with a glacier overhanging an upstream lake in the steep valley. Rupert Stuart-Smith of Oxford University, who has just published an analysis of a glacier melting disaster in waiting in the Andes, talks about the impacts of climate change on the stability of mountain glaciers. And Do you find your bearings quickly or are you easily disorientated? Do your friends trust you with the directions in a new city? Finding our way in the physical world – whether that’s around a building or a city - is an important everyday capability, one that has been integral to human survival. This week CrowdScience listeners want to know whether some people are ‘naturally’ better at navigating, so presenter Marnie Chesterton sets her compass and journeys into the human brain. Accompanied by psychologists and neuroscientists Marnie learns how humans perceive their environment, recall routes and orientate themselves in unfamiliar spaces. We ask are some navigational strategies better than others?Marnie also hears that the country you live in might be a good predictor of your navigation skills and how growing up in the countryside may give you an wayfaring advantage. But is our navigational ability down to biology or experience, and can we improve it? With much of our modern map use being delegated to smartphones, Marnie explores what implications an over-reliance on GPS technology might have for our brain health.(Image: An illustration of NASA’s Perseverance rover landing on Mars. Credit NASA/JPL-Caltech) Presenter: Roland Pease Producer: Deborah Cohen

A new trial is about to start in the UK, seeing if different vaccines can be mixed and matched in a two-dose schedule, and whether the timing matters. Governments want to know the answer as vaccines are in short supply. Oxford University’s Matthew Snape takes Roland Pease through the thinking. Despite the numbers of vaccines being approved for use we still need treatments for Covid-19. A team at the University of North Carolina is upgrading the kind of manufactured antibodies that have been used to treat patients during the pandemic, monoclonal antibodies. Lisa Gralinski explains how they are designing souped-up antibodies that’ll neutralise not just SARS-CoV-2, but a whole range of coronaviruses. Before global warming, the big ecological worry that exercised environmentalists was acid rain. We’d routinely see pictures of forests across the world dying because of the acid soaking they’d had poisoning the soil. In a way, this has been one of environmental activism’s success stories. The culprit was sulphur in coal and in forecourt fuels – which could be removed, with immediate effect on air quality. But biogeochemist Tobias Goldhammer of the Leibniz Institute in Berlin and colleagues have found that sulphur, from other sources, is still polluting water courses. There’s been debate over when and where dogs became man’s best friend. Geoff Marsh reports on new research from archaeology and genetics that puts the time at around 20,000 years ago and the place as Siberia.Could being happier help us fight infectious disease?As the world embarks on a mass vaccination programme to protect populations from Covid-19, Crowdscience asks whether our mood has any impact on our immune systems. In other words, could being happier help us fight infectious diseases? Marnie Chesterton explores how our mental wellbeing can impact our physical health and hears that stress and anxiety make it harder for our natural defence systems to kick in – a field known as psychoneuroimmunology. Professor Kavita Vedhara from the University of Nottingham explains flu jabs are less successful in patients with chronic stress. So scientists are coming up with non-pharmacological ways to improve vaccine efficiency. We investigate the idea that watching a short feel-good video before receiving the inoculation could lead to increased production of antibodies to a virus. And talk to Professor Richard Davidson who says mindfulness reduces stress and makes vaccines more effective.

Northern white rhinos are extinct in the wild and there are just two females in captivity in Kenya. Conservationists are working on an artificial breeding programme, using eggs from the females and sperm from a deceased male. Now five embryos have been created. Thomas Hildebrandt of the Leibniz Institute for Zoo and Wildlife Research in Berlin explained the research.President Biden’s first executive order was what’s being called the hundred-day mask mandate. The day before the inauguration a massive analysis of mask-wearing and COVID rates demonstrated a clear, if small, benefit. Epidemiologist Ben Rader told Roland Pease that it got over 300,000 opinions by using the online questionnaire, SurveyMonkey.After the alarming series of record-breaking heatwaves last year, global warming is causing specific problems in the innumerable lakes around the world. Lakes are ecologically particularly vulnerable to extremes. The European Space Agency’s Yestyn Woolway has been analysing past trends, and modelling the future.2020 delivered a record year in hurricanes, which caused around $60 billion dollars in damage to the US alone, according to one estimate. A new technology called Airborne Phased-Array Radar promises to improve the measurements that are currently made by planes that fly right into the eye of the hurricanes, and make the missions safe. It’s being developed at the National Centre for Atmospheric Research and Roland discussed the new technology with the Director of NCAR, Vanda Grubišić.And Covid-19 has prompted a cleaning frenzy. CrowdScience listener William works as a personal trainer in a gym, and while cleaning’s always been part of his job, it’s now taken over much of his working day. He’s constantly wiping down equipment and doing regular deep cleans, and he reckons he can sanitize his hands 40 times in one shift.This kind of routine might strike a chord with many of us, and it’s certainly vital to take hygiene seriously during times of pandemic.But could there be any downsides to all this extra cleaning? There’s a whole world of microbes out there: some, like SARS-CoV-2, make us sick, but others are essential for our health. A rich microbiome is linked to a healthy immune system, while ‘good’ microbes help keep ‘bad’ ones at bay. And what about the chemicals in cleaning products – do they have any unintended consequences for our health?CrowdScience turns to the experts to ask whether our supercharged hygiene routines could damage our immune systems, or promote the spread of superbugs. And we hear why, as long as we have a good diet, plenty of fresh air, and ideally a furry pet, we don’t need to worry too much about being too clean.(Image; Najin and Fatu, the only two remaining female northern white rhinos graze in their paddock. Credit: Tony Karumba/AFP via Getty Images)

After collecting data for more than twelve years the North American Nanohertz Observatory for Gravitational Waves (NANOGrav) announced it may have detected new kinds of gravitational waves caused by colliding supermassive black holes. Professor Chiara Mingarelli of the University of Connecticut tells Roland Pease why this is such an exciting discovery.Supermassive black holes are at the heart of galaxies and they are the engines of quasars, the brightest light sources in the heavens that can be seen across the expanse of the Universe. A team including Professor Xiaohui Fan of the University of Arizona has identified the oldest quasar in the universe. The SARS-CoV-2 virus looks much like bat coronaviruses, but the mostly likely route into humans involved some other infected animal. Roland talks to Dr Dalan Bailey of The Pirbright Institute about how he has been looking for possible intermediaries.A new study that looks into the genetics of twins and their families in Iceland shows that identical twins aren’t really identical. Kari Stefansson of the Icelandic genome company, DeCode, explains that the differences can appear when the twins are at the embryonic stage.And , When it comes to speed, humans have got nothing on cheetahs - or greyhounds, kangaroos or zebras for that matter. It’s over long distances we really come into our own: when running for hours or even days, our body structure and excellent sweating skills make us able to outpace much faster mammals.But what are the limits of human endurance? Can we run ever further and faster, and what’s the best diet to fuel such ambitions?This week’s questions come from two CrowdScience listeners in Japan who already know a fair bit about stamina, having run several marathons and long-distance triathlons between them. We head to Greece, legendary birthplace of the marathon, to witness an even more arduous challenge: hundreds of athletes following in the footsteps of the ancient Greek messenger Pheidippides, to run an astonishing 246km across the country. The ever-so-slightly less fit CrowdScience team do our best to keep up, and try to discover the secrets of these runners’ incredible endurance.(Image: Representative illustration of the Earth embedded in space-time which is deformed by the background gravitational waves and its effects on radio signals coming from observed pulsars. Credit: Tonia Klein / NANOGrav)

Mutant strains of SARS-Cov2 have been identified not only in the UK, where it was first identified, but also in at least 30 other countries. And to complicate matters, another alarming variant, with some similar mutations, has arisen in South Africa. Roland Pease talks to Ravi Gupta, a virologist at Cambridge University and Tulio de Oliveira of the University of KwaZulu Natal about these new strains. There’s only so much that can be learned about the virus by looking at the patients it infects. Thanks to techniques developed to study HIV, Ebola, flu and other viruses in the past, researchers have methods for growing key parts of viral structures in the lab and watching closely how they behave in cell cultures. Jeremy Luban of the University of Massachusetts and Alli Greaney at the Fred Hutchinson Cancer Research Center talk to Roland about how they are studying the biology of the mutations to discover how the new strains might respond to vaccines.And, one of the more surprising consequences of the pandemic has been the trend for people wanting to move out of cities and back to the countryside. Not everyone has that privilege of course, but undoubtedly for some living in urban areas during lockdown, the lack of access to green spaces took its toll on their mental health and physical well-being. Now, with renewed hope of a global vaccine roll-out, ensuring more people have better access to nature is more important than ever, especially in cities of glass, steel and concrete. Italian CrowdScience listener Enrica loves nothing better than walking along the verdant riverbank near her home after a hard week at work. But is this activity doing more than making her feel good? Is it having an actual effect on her health? Presenter Anand Jagatia meets Enrica and visits a radical scheme in the city of Milan, where officials have been working hard to increase urban green features and have committed to planting 3 million trees and building twenty new parks by 2030.One such idea is the innovative Bosco Verticale - or vertical forest, planted up the side of two high rises apartment blocks. Amongst other benefits It’s hoped it could provide cooling microclimates to reduce the dangers (Image: Swab test. Credit: Getty Images)

This has been an incredible year for scientific advance and collaboration, epitomised by the roll out of vaccines that didn’t exist a year ago, against a virus that no one had ever heard of . And yet at the same time its been a year of incredible frustration. We are stil largely using the same methods to counter the virus that were used in past pandemics, going back a hundred years. Here we look back at key the findings on who is most susceptible and why, and ask how to improve the strategies for reducing transmission. As regular listeners may recall, CrowdScience has delved into the strange world of fungi before, as we dug down into the forest floor to reveal how plants and trees are connected to the vast mycelial network known as the “wood wide web”. But what makes this network possible and how might it have evolved? Fungi are incredible clever, or at least , it appears that they’re capable of displaying complex behaviour that gives them the appearance of intelligence. In this episode, we speak to fungal ecologist and author of a new book, Merlin Sheldrake, about fungal “brains”, the evolution of magic mushrooms and zombie insects – the astonishing way certain fungi can take over the bodies of ants and wasps in order to sow their spores above ground.(Image: Getty Images)

In our first programme of the year, we gathered a group of scientific experts directly involved in analysing the structure and impact of the SARS- Cov-2 coronavirus. There were concerns over the emergence of two new variants, Alfa and Beta, especially whether these variants might spread more quickly or outmanoeuvre the suite of new vaccines that were about to be rolled out. And now with Omicron, the same questions are being asked about this variant’s ability to spread and overcome our defences. We’ve invited the same scientists back to give us their assessment of our journey with Covid 19 over the past year and discuss their findings on Omicron.Featuring: Ravi Gupta Professor of Clinical Microbiology at the University of Cambridge Tulio De Oliveria Professor on Bioinformatics, Stellenbosch University, South Africa Dr. Allie Greaney From the Medical Scientist Training Program at the University of Washington School of Medicine And Professor Jeremy Luban from the Broad Institute of MIT and Harvard Should you wash your eggs? Well, believe it or not, there is quite an international debate about this question from CrowdScience listener Susan. In Canada, where Susan grew up, commercially sold eggs are washed before they reach stores, whereas in the UK where she is now living they are not. So what is best to avoid contamination?It’s one of a number of egg-themed questions that CrowdScience tries to crack in this episode. One of our presenters, Marnie Chesterton, heads over to Susan’s home in London to cook some eggs and explore other egg cooking questions from our listeners, such as what is the science behind frying an egg without it sticking to the pan and why are some boiled eggs harder to shell than others?Meanwhile, this episode’s other presenter, Anand Jagatia, explores questions about eggs after they have hatched. He investigates a case of curious chicken behaviour sent in by listener Laurie, as well as working out how a cuckoo knows it’s a cuckoo when it’s been raised in another bird’s nest.Featuring: Dr. Vincent Guyonnet, Dr. Valérie Lechevalier, Dr. Siobhan Abeyesinghe and Dr. Ros Gloag(Image:Getty Images)

It was the end of December 2019 when reports of a new flu like infection first came out of China. Within weeks millions of people were in lockdown as the virus took hold around the world.In this programme we look back and revisit the scientists who were ready, those who had been studying bat coronaviruses and warning of their pandemic potential. The scientific response was immediate. The coronavirus tests now used across the world were being developed within a few hours of news of the outbreak in China, and the vaccines we now have licenced for use began to be formulated just a few days later.At Christmas, is there a better gift than knowledge? CrowdScience has cooked up its own version of 'secret Santa', with members of the team setting one another the challenge of answering surprising questions from all over the world.Are humans the only animals to exercise? Can you get colder than absolute zero? Why are sounds louder at night? When it comes to food dropped on the floor, is there such thing as the "three-second rule"? And, does honey really have healing properties?Producers and presenters from the CrowdScience team speak to all manner of experts, from zoologists through to material scientists, to find the answers.(Image: Getty Images)

This week the UK Health secretary raised concerns over a new variant of SARS- CoV-2 currently spreading across Europe. Viruses mutate all the time so it’s no surprise that a new form of the one causing Covid -19 would emerge. However, virologist Ravi Gupta who analysed the new strain says we need to be weary in case future strains mutate in ways that could overcome vaccines.Immunologist Akiko Iwasaki is part of a team looking at the impact of Covid -19 on our immune system. Her research has uncovered autoantibodies linked to infection with the virus. These are responsible for a number of autoimmune diseases. The finding goes some way to explaining the symptoms seen by some people long after a Covid -19 infection.And how clever are ravens? According to behavioural scientist Simone Pika at the Max Planck Institute for Ornithology in many ways they are up there with chimps or young children. She found they performed well in tests designed for primates.Following the dinosaur destroying meteor strike where was the best place for life to develop a new? Geologists, David Kring and Tim Bralower, think they’ve found the answer hidden in plain sight.CrowdScience listener Simon has a problem. He’s always bumping into things, dropping tools and knocking stuff over. And he’s sick of it. He wants to know what is going on. Was he born like this? Or is it contagious? And most importantly, can he doing anything about it or is he going to be the proverbial ‘bull in a china shop’ for the rest of his life?Host Anand Jagatia gets on the case, investigating the complex coordination needed for the simplest movements, like throwing a ball and catching it. With help from Dr Andrew Green, an exercise physiologist from Johannesburg University, he delves into our secret “sixth sense” – proprioception, which helps us locate our limbs without looking. Anand discovers that an easy task, like kicking a football, needs multiple parts of the brain to coordinate in order to work smoothly. Assistant Professor Jessica Bernard from Texas AMU studies the brain, particularly the cerebellum, a part that controls smooth movements. Dr Bernard explains how tiny glitches and larger lesions in different parts of the brain can make us clumsy in different ways. And how we use our thinking powers to stay balanced; a reason why, as your memory goes with old age, you’re more prone to falling over.Our listener is not alone. Around the world, there is an under- diagnosed condition that affects millions of us. Developmental Coordination Disorder (DCD), also known as dyspraxia is a motor coordination condition that affects 5% of the global population. As Professor Amanda Kirby from the University of South Wales and CEO of Do-It solutions explains, if you can’t tie shoelaces, catch a ball and your handwriting is awful, there’s a chance that you have DCD. There’s a large genetic component, so you are likely to come from a clumsy family.There’s no cure for DCD/Dyspraxia but all of us are capable of becoming better at a chosen task, and there’s a common pathway to mastery, whether that’s bike mechanics or open heart surgery. Professor Roger Kneebone is the author of Becoming Expert, and he talks to Simon about possible solutions to clumsiness, including accepting and living with it.[IMAGE: Getty Images]

Pictures of coffins and mass graves seen by satellites showed that Manaus has been badly affected by Covid- 19. Now analysis of blood samples shows the extent to which the virus took hold in the Amazon city earlier this year. Investigators Ester Sabino and Lewis Buss from Brazil’s University of Sao Paulo discuss how and why the virus spread.Humanity has been modifying the environment for millennia, but have we now reached a point where it’s all too much? An analysis by Emily Elhacham from Tel Aviv University shows the amount of stuff produced by humanity, from plastics to buildings now has a greater mass than all natural biomass on the planet.And China has been to the moon. Space watcher Andrew Jones tells us how the robotic mission mimics the manned missions of the 1960s and 70s.The space between stars is usually measured in light years, but this makes it less easy to acknowledge the true scale of the distance. Even the closest star system to Earth, Proxima Centauri, is 4.2 light years or 40.13 trillion kilometres from Earth. If we are ever going to bridge the gap between the stars, we will have to have some very fast spaceships, with extremely reliable, long-lasting technology on board.So does science allow for these spacecraft to exist? That’s what listener Allan wants to know, and to find out, Presenter Anand Jagatia speaks with Tracy Drain, a systems engineer at NASA JPL responsible for overseeing the development and missions of multiple unmanned interplanetary probes including some around Jupiter and Mars. She tells us the challenges involved with simply keeping our spacecraft working for the long-haul.Even if we can overcome issues of wear and tear over time, powering a ship to other star systems will not be easy. Today’s chemical rockets are too inefficient for the job, so we speak with Rachel Moloney, a researcher in electric propulsion to ask if this relatively new technology could power ships through interstellar space.Faster than light travel is the solution most often found in Science Fiction, but it goes against Einstein’s laws of relativity. Is there a way around it? Theoretical physicist Professor Miguel Alcubierre thinks there may be, and he describes the way a spaceship may be able to create a bubble of spacetime around itself to move faster than light without breaking these fixed laws. But there’s a catch... (Image: Getty Images)