Discovery

Every three seconds someone is diagnosed with dementia, and two thirds of the cases are Alzheimer’s Disease. As the global population ages, this is becoming an epidemic, and with no cures currently available for the collection of neurodegenerative conditions that include Alzheimer’s, Parkinson’s and Motor Neurone Disease the public and personal cost is escalating. Sue Broom reports on new efforts to find ways to stop the progress of these diseases for the first time, and to bring treatment for neurodegenerative conditions in line with those of cancer and heart disease.Picture: Human head, Credit: Science Photo LibraryPresenter: Sue Broom

Two deadly cases today sent in by listeners to curiouscases@bbc.co.ukThe Dark Star "What's inside a black hole and could we fly a spaceship inside?" asks Jorge Luis Alvarez from Mexico City.Astrophysicist Sheila Rowan explains how we know invisible black holes actually exist. Plus cosmologist Andrew Pontzen is on hand to help cook one up.But which of our intrepid doctors will volunteer to fly into the heart of a black hole?Kate Bush’s Sonic Weapon "It started while listening to the excellent Experiment IV by Kate Bush. The premise of the song is of a band who secretly work for the military to create a 'sound that could kill someone'. Is it scientifically possible to do this?" asks Paul Goodfield.Hannah consults acoustic engineer Trevor Cox to ask if sonic weapons could kill. And Adam delves into subsonic frequencies with parapsychologist Chris French to investigate their spooky effects.Plus the team investigates the Curious Case of the Embassy in Cuba – could a sonic weapon really be responsible for the wide-ranging symptoms reported by American diplomats in Havana?You can send your scientific mysteries for the team to investigate to: curiouscases@bbc.co.ukPicture: A computer-generated image of a rich star field with a Black Hole in front of it which distorts starlight into a brilliant ring around itself, Credit: BBC Producer: Michelle Martin

The Polar Opposite No one knows why the Earth's magnetic North and South poles swap. But polar reversals have happened hundreds of times over the history of the Earth. John Turk emailed curiouscases@bbc.co.uk to ask, “when is the next pole swap due and what will happen to us?” Featuring Prof Lucie Green from Mullard Space Science Laboratory and Dr Phil Livermore from the University of Leeds. Plus, astronaut Terry Virts, author of The View from Above, describes his experiences of a strange magnetic glitch in the earth's magnetic field, known as The Bermuda Triangle of Space.The World That Turns "Why does the Earth spin?" asks Joe Wills from Accra in Ghana. Hannah quizzes cosmologist Andrew Pontzen about the birth of the Solar System. BBC weatherman John Hammond describes the curious things that would happen if the Earth spun the opposite way. Send your questions to: curiouscases@bbc.co.ukPicture: The Earth reflecting light from the sun whilst aboard the International Space Station, Credit: Alexander Gerst / ESA via Getty ImagesProducer: Michelle Martin

The Astronomical Balloon "How far up can a helium balloon go? Could it go out to space?" asks Juliet Gok, aged 9. This calls for an experiment! Dr Keri Nicholl helps Adam launch a party balloon and track its ascent. But their test doesn't quite go to plan. Meanwhile, Hannah discovers where space begins by asking Public Astronomer Dr Marek Kukula, from the Royal Observatory Greenwich. Send your Curious Cases to the team: curiouscases@bbc.co.ukThe Forgetful Child "Why don't we remember the first few years of our lives?" asks David Foulger from Cheltenham. The team investigate the phenomenon of 'infant amnesia' with Catherine Loveday from the University of Westminster. 40% of us claim to remember being under two years old and 18% recall being babies. But can we really trust these early memories? Martin Conway from City University thinks not.Picture: A baby contemplates the sole of its foot, circa 1950, Credit: H. Armstrong Roberts/Retrofile/Hulton Archive/Getty ImagesProducer: Michelle Martin.

The Astronomical Balloon "How far up can a helium balloon go? Could it go out to space?" asks Juliet Gok, aged 9. This calls for an experiment! Dr Keri Nicholl helps Adam launch a party balloon and track its ascent. But their test doesn't quite go to plan. Meanwhile, Hannah discovers where space begins by asking Public Astronomer Dr Marek Kukula, from the Royal Observatory Greenwich. Send your Curious Cases to the team: curiouscases@bbc.co.ukThe Forgetful Child "Why don't we remember the first few years of our lives?" asks David Foulger from Cheltenham. The team investigate the phenomenon of 'infant amnesia' with Catherine Loveday from the University of Westminster. 40% of us claim to remember being under two years old and 18% recall being babies. But can we really trust these early memories? Martin Conway from City University thinks not.Picture: Baby Foot, Credit H. Armstrong Roberts/Retrofile/Hulton Archive/Getty ImagesProducer: Michelle Martin.

“How on earth do cats find their way back to their previous home when they move house?" asks Vicky Cole from Nairobi in Kenya. Our enduring love for our feline friends began when Egyptian pharaohs began to welcome domesticated moggies into their homes. Pictured reclining in baskets at the feet of royalty, pet cats soon became fashionable throughout society in Egypt. Today they are the most popular pet in the world, and home is definitely where their hearts lie. "Whereas dogs are bonded to people, cats are bonded to place," explains zoologist Dr John Bradshaw. "It's very typical for them to try and find their way back to their old house when you move." But how do they do it? And if their navigational skills are so good, why do they get lost? Prof Matthew Cobb reveals the super-senses that cats possess, and how to spot when your pet is deploying them.Itchy and Scratchy "What is an itch and how does scratching stop it? Why does scratching some itches feel so good?!" asks Xander Tarver from West Sussex in England.Our doctors set off to probe the mysteries of itch, and discover that this overlooked area of medicine is revealing surprising results about the human brain. From why itching is contagious to why scratching is pleasurable, we get under the skin of this medical mystery. The programme features interviews with neuroscientist Prof Francis McGlone from Liverpool John Moores University and dermatologist Dr Brian Kim from the Center for the Study of Itch at Washington University. Yes, that is a real place.If you have any Curious Cases for the team to solve please email curiouscases@bbc.co.uk.Presenters: Adam Rutherford, Hannah Fry Producer: Michelle Martin(Photo: Cat, Credit: Chris J Ratcliffe/Getty Images)

Science sleuths Drs Rutherford & Fry take on everyday mysteries and solve them with the power of science. Two cases in this episode concerning the inner workings of our bodies, and not for the faint hearted! The Broken Stool "Science tells us that our body houses microbial organisms. Then how much our weight is really our weight? If I am overweight, is it because of my own body cells or excess microflora?" asks Ajay Mathur from Mumbai in India.Adam bravely sends off a personal sample to the 'Map My Gut' project at St Thomas' Hospital to have his microbes mapped. Prof Tim Spector reveals the shocking results - a diet of fried breakfasts and fizzy drinks has left his guts in disarray. But help is at hand to makeover his bacterial lodgers.Science writer Ed Yong, author of 'I Contain Multitudes', reveals how much our microbes weigh. We're just beginning to discover the vast array of vital functions they perform, from controlling our weight, immune system and perhaps even influencing our mood and behaviour. A Code in Blood "Why do we have different blood types?" asks Doug from Norfolk in the UK.The average adult human has around 30 trillion red blood cells, they make up a quarter of the total number of cells in the body. We have dozens of different blood groups, but normally we're tested for just two - ABO and Rhesus factor. Adam and Hannah delve into the gory world of blood and the early history of blood transfusions, to discover why we have blood groups and how they differ around the world.Featuring interviews with Dr Jo Mountford, from the Scottish National Blood Transfusion Service and immunologist Dr Sheena Cruikshank from the University of Manchester.If you have any Curious Cases for the team to solve please email curiouscases@bbc.co.uk.Presenters: Adam Rutherford, Hannah Fry Producer: Michelle MartinImage: Illustration of red blood cells in a blood vessel. Copyright: Science Photo Library

Sydney Brenner was one of the 20th Century’s greatest biologists. Born 90 years ago in South Africa to impoverished immigrant parents, Dr Brenner became a leading figure in the biological revolution that followed the discovery of the structure of DNA by Crick and Watson, using data from Rosalind Franklin, in the 1950s. Brenner’s insights and inventive experiments laid foundation stones for new science of molecular biology and the genetic age in which we live today, from the Human Genome Project to gene editing. Sydney Brenner talks to biologist and historian Matthew Cobb of the University of Manchester about this thrilling period in biological science, and Dr Brenner’s 20 year-long collaboration with DNA pioneer Francis Crick: a friendship which generated some of their most creative research. Producer: Andrew Luck-BakerPicture: Sydney Brenner, Credit: Cold Spring Harbor Lab Archive

This is a big story about a little snail. Biologist Helen Scales relates an epic tale that spans the globe and involves calamity, tragedy, extinction and we hope, salvation. It stars the tiny tree-dwelling mollusc from French Polynesia, Partula, a snail that has captivated scientists for centuries. Like Charles Darwin studied finches on the Galapagos, Partula became an icon of evolution because, in the living laboratories of the Pacific islands, it had evolved into multiple species. But a calamity drove Partula to extinction, when a botched biological control, the predatory Rosy Wolf Snail, was introduced. It was supposed to eat another problem mollusc, but in a cruel twist, devoured tiny Partula instead. An international rescue mission was scrambled to save a species and from just one or two rescued individuals, populations of this snail species have been built up over thirty years in captive breeding programmes in zoos around the world. And now, in the nailbiting sequel, we track Partula’s journey home.Picture: Reintroduced Partula dispersing on Moorea in French Polynesia, Credit: ZSLPresenter: Helen Scales Producer: Fiona Hill

For more than 200 years Britain ruled India, bringing many aspects of British culture to India - including European science developed during the enlightenment. However centuries earlier India had already pioneered work in astronomy, mathematics and engineering. How was India’s scientific progress affected by colonialism? Did British rule hold the country back, or did it drive it forward? Presented by Angela Saini.Picture: The Indian Space Research Organisation (ISRO) communication satellite GSAT-19, carried onboard the Geosynchronous Satellite Launch Vehicle (GSLV-mark III ), launches at Sriharikota on June 5, 2017, Credit: ARUN SANKAR/AFP/Getty Images