BBC Inside Science

Neuroscientist Miguel Nicolelis is one of the world's leading researchers into using the mind to control machines. He is involved in the "Walk Again Project" which aims to build a suit that a paraplegic person can wear and control so that he or she can kick a football at the opening ceremony of the 2014 World Cup in Brazil. Adam is joined by biomedical engineer, Professor Christopher James from Warwick University, who puts the field of Brain Machine Interfaces in context.Work published last week by Professor Ziv Williams looks at the possibility of rewiring the body. Paralysis is normally confined to spinal cord damage, not the limbs themselves. Ziv Williams' work aims to use implanted chips to bypass the injury and have the individual control their own paralysed arms.Listeners ask if there is a gene for fundamentalist intolerance. We put the question to Professor Tim Spector, author of Identically Different.Adam Rutherford heads down to the psychology department at London's South Bank University... for a pint. Dr Tony Moss has built a fake pub, complete with lighting, music and even a fruit machine, to make drinkers feel that they are in a real bar. He says the venue treads a middle ground between a sterile lab, and an actual pub, where there are too many variables to reliably study behaviour.Professor John Shepherd from Cardiff studies alcohol and behaviour from the other end - the drunken nights out that end up in A&E. A few simple initiatives have helped reduce violence levels by 40%Producer: Fiona Roberts.

Bees - Nearly all bees in the UK suffering serious declines. They're mostly threatened by habitat and land-use change. But disease also plays a part. Adam Rutherford talks to Professor Mark Brown about new work he's done looking at the evidence of diseases harboured by honeybees, spilling over into wild bumblebees.Pain and epigenetics - Marnie Chesterton goes to Kings College, London to watch identical twins being tested for pain tolerance. The study is to gain insight into the genetic components of pain perception. One area which is fascinating researchers like Professor Tim Spector is the role of epigenetics in how we process pain. Our epigenome is a system that changes the way our DNA is interpreted. Genes can be dialled up or down, like a dimmer switch, by adding little chemical tags to the DNA. These chemical tags, unlike DNA, are changeable, in response to the changing environment. So could the way we live affect the pain we feel?Whales from Space - More listeners' questions, this time, asking whether surveys using images from satellites to see whales underwater, could be hijacked by whale hunters? Peter Fretwell from the British Antarctic Survey has the answer.Genetics of sexual preference - The media is all of a twitter this week over unpublished work recently revealed on research looking for genes related to homosexuality. We hear from Professor Tim Spector on the topic, and Adam talks to Professor Steve Jones about the science.Producer: Fiona Roberts.

Whales from Space. Scientists have demonstrated how new satellite technology can be used to count whales, and ultimately estimate their population size. Using Very High Resolution (VHR) satellite imagery, alongside image processing software, they were able to automatically detect and count whales breeding in part of the Golfo Nuevo, Peninsula Valdes in Argentina.The new method could revolutionise how whale population size is estimated. Marine mammals are extremely difficult to count on a large scale and traditional methods are costly, inaccurate and dangerous; several whales researchers have died in light aircraft accidents. How long will the floods last? Is this a trend caused by climate change? Should I turn on the kitchen taps so that house is at least flooded with clean water? We put listeners' flood questions to experts from the Centre of Ecology and Hydrology and the British Geological Survey.The instrument we're shown this week is from JET (Joint European Torus) in Culham,. It's the world's largest 'tokamak' - a type of nuclear fusion reactor. The hope is that in a few decades it could be supplying much of the world's electricity. It works by fusing nuclei of hydrogen together to produce helium and a lot of excess energy. It's the power source of the Universe, as all stars run on fusion energy. But on Earth we have to go to much more extreme conditions to achieve it. Upwards of 100 million degrees Celsius, which is around ten times hotter than the Sun. Joanne Flannagan, shows us her lasers which measure the hot fusion plasma inside JET.CERN wants a new tunnel. The 27km long, Large Hadron Collider in Geneva found evidence of the Higgs boson recently. But if we want to know more about this elusive particle and others that make up our universe, the physicists say they're going to have to go bigger. With a 100km long tunnel, in fact. Talks are afoot as to where and how they will build it. But Lucie asks reporter Roland Pease whether it'll be worth it?The current Discoveries exhibition at Two Temple Place, on the banks of the Thames, brings together treasures from eight University of Cambridge museums, in a beautiful period building, built by Waldorf Astor. The show combines objects from science and arts collections to explore the theme of 'Discoveries'. Curator Professor Nick Thomas gives Lucie Green a tour.Producer: Fiona Roberts.

The warning that floods are likely to become more common, or more severe, won't be a high priority for those with homes currently deluged. But it is something architects, engineers and planners have been taking very seriously. Dr. Adam Rutherford finds out about some of the innovations, both in UK and abroad, being designed for homes in areas prone to flooding - from simple door guards and waterproofing which can be retrofitted to existing houses - to entire city re-landscaping, or 'waterscaping' which aims to make room for the river, rather than fighting against it.Last week Adam talked about research showing that most people of European or East Asian descent carry a small percentage of Neanderthal DNA - about 2%. He examined some of the physical characteristics we may have got from the genes of our ancient cousins. This week Inside Science addresses some of the questions this fascinating work prompted.A new study in the journal Neuron this week, looks at what happens in the brain when one of the senses is dulled. Dr. Patrick Kanold, from the University of Maryland in the States, and his colleagues simulated blindness in mice by keeping them in the dark for a week, to see what happened to the parts of their brains involved in hearing. The found that the mouse's hearing improved. We sometimes talk about the brain being 'hardwired': all the neurons locked in place from early childhood. It was assumed that there was only a short, finite period when the brain was still capable of changing, but the new research shows parts of the brain still has room to manoeuvre.A recurring problem in science is that we are far better at collecting vast amounts of scientific data than we are at actually analysing them. To combat this problem, the charity Cancer Research UK have just launched a mobile phone game, 'Genes In Space', that farms statistical analysis out to the masses. Under the guise of flying a spaceship through a meteor storm, game players actually navigate their way through genetic sequence data from breast cancer patients. The information on the virtual path they take is automatically uploaded to the database and fed back into the scientific process.Producer: Fiona Roberts.

Discover the genetic legacy of Neanderthals in modern humans, including disease susceptibilities and physical traits. Learn about the reemergence of deadly plagues like the Justinian plague, and how scientists are studying ancient plague DNA. Explore the intricate timing precision in string quartets and how it can be applied to robotics. Uncover a revolutionary acid treatment for stem cell therapy that could transform medical research.

The Higgs boson has been discovered, providing the final piece of the jigsaw puzzle for the Standard Model of particle physics, a description of how the universe works. But what physicists haven't found yet, which they should have, are supersymmetry or SUSY particles. Roland Pease attended a recent meeting of top physicists, and shares with Adam Rutherford the latest discussions about where to look next.The history of neutrinos is littered with interesting characters. It was Wolfgang Pauli who first suggested their existence. Pauli was so unsettled by his proposal that he bet a case of champagne against anyone being able to discover these "pathologically shy" particles. Since then, scientists have built ever more elaborate experiments to try and detect these particles. Ray Jayawardhana, Professor of Astrophysics and author of a new book "The Neutrino Hunters" explains more about the most abundant particle in the universe.This week's Show Us Your Instrument is a tool used to help scientists measure the glaciers in the Antarctic. Julian Dowdeswell, a glaciologist from the University of Cambridge, uses an echo-locator to look at the dynamics of large ice masses and their response to climate change.Fungi, not viewed favourably by gardeners, can be good for rainforest biodiversity. Dr Owen Lewis from Oxford University tells Melissa Hogenboom that plots sprayed with fungicide soon become dominated by a few species at the expense of many others, leading to a marked drop in diversity.A mysterious illness killing dogs has been in the headlines this week. David Walker a veterinary specialist, says that although it's not clear what's causing the disease, people should not panic.

Geneticist Professor Robert Green debates FDA's stance on personal genetics kits. Imperial College researches persister cells causing recurrent infections. University of Aberdeen maps global earthquake hazards. Scorpion venom evolution discussed.

Scientists following in the footsteps of Edwardian explorer, Douglas Mawson, have been trapped in pack ice in the Antarctic. The Chinese vessel that came to their rescue also became "beset" in the ice. The BBC's Andrew Luck Baker talks to Adam Rutherford about the catacylsmic event that caused multi-year ice to break away and trap the Academik Shokalskiy and Professor John Turner of the British Antarctic Survey underlines the importance of differentiating between extreme weather events and the impact of climate change.A team at Rothamsted Research in Hertfordshire has succeeded in genetically engineering plant seeds to contain the Omega-3 oil usually found in oily fish. Seeds from Camelina sativa (false flax) plants were modified using genes from microalgae - the primary organisms that produce these beneficial fatty acids.The oil has now been incorporated into salmon feed to assess whether it's a viable alternative to wild fish oil. Dr Johnathan Napier tells Melissa Hogenboom that he hopes the plants will provide a sustainable source of long chain polyunsaturated fatty acids.From fossils we know an awful lot about the animals that walked on the Earth, swam in the sea and flew in the air. But fossils have never been good at revealing the colour of these animals. With increasingly sophisticated sampling techniques however, scientists are starting to get a much better, technicolour glimpse into these extinct fauna. And it turns out that colour played a much more important role than just camouflage and decoration. Johan Lindgren form Lund University in Sweden has been finding out how the pigment, melanin, allowed ancient marine reptiles to travel all over the oceanic globe.Show Us Your Instrument: Dr Andrew Polaszek, Head of Terrestrial Invertebrates at the Natural History Museum reveals his compound microscope (with Nomarski Differential Interference Contrast) which he uses to discover "hidden biodiversity", particularly in parasitoid wasps.Stephen Hawking threw a party for time travellers and issued the invitation after the event. Astrophysicists after a long poker game decided to use Twitter instead, to flush out the time travellers in our midst. Professor Robert Nemiroff from Michigan Tech University and his students mined social media for references to the Comet ISON and the naming of the new Pope Francis, before both those events had actually happened. Producer: Fiona Hill.

Chris Stringer, Director of AHOB, along with other experts, discuss the ancient human occupation of Britain. They delve into the oldest human life in Britain found in Norfolk, exotic animals unearthed in London, and the significance of the 'Vole Clock' in dating. The podcast also explores advancements in carbon dating and the insights gained from mammal fossils in understanding ancient climates.

Professor Alice Roberts discusses bacteriophages as a potential weapon against antibiotic-resistant infections. Paul Hebert leads the global DNA barcoding project. Bees are attracted to flowers by electric fields. Claire Turner demonstrates disease detection through breath analysis.