BBC Inside Science

BBC Radio 4
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Mar 10, 2016 • 28min

Gain-of-function research, Mindfulness, Women in science, Snake locomotion

This week in the US, public discussions are taking place into controversial Gain of Function research. Who should decide the limits of studies where scientists make new, deadlier viruses in the laboratory? Dr Filippa Lentzos, biosecurity expert from King's College, London, lists a litany of accidental security breaches from the past. Should we stop this kind of dangerous research, or encourage it, in the interests of national security?Mindfulness is a hot topic at the moment. As part of BBC School Report, students from Connaught School for Girls in Leytonstone have tested themselves to see whether meditation helps with their studies. Tracey Logan discusses the scientific research underpinning this trend with psychologist Claudia Hammond. The Royal Society released a report this week entitled "Parent, Carer, Scientist." The idea is to encourage an environment in research institutions where scientists can have a life as well as a vocation. Professor Ottoline Leyser, Professor of Plant Development and Director of Cambridge University's Sainsbury Laboratory, discusses what needs to change to ensure more female scientists to stay in science.How do snakes move across sand? BBC science reporter Jonathan Webb meets Perrin Schiebel, at the Georgia Institute of Technology. A physicist, she works with a giant sand pit and high-speed cameras, putting snakes through their paces to unpick how they can push their bodies off the sand without sinking into it.
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Mar 3, 2016 • 28min

UK's longest-running cohort study, The Brain prize, Hairy genetics

This week is birthday time for the 3000-strong group of 70 year olds who might qualify for the title of longest-serving science guinea pigs. Participants in The National Survey for Health and Development cohort study have been closely monitored since their birth in 1946. Joining Adam Rutherford to discuss how this and other similar studies have influenced our lives, and what data we should collect on today's babies, are the Head of the National Survey for Health and Development at MRC's Unit for Lifelong Health and Ageing at University College London, Professor Diana Kuh, and Professor Debbie Lawlor, programme lead at the Medical Research Council's epidemiology unit at Bristol University.A team of British team has picked up £1 million from The Brain Prize, which is issued by a Danish Charity annually. Tim Bliss, Graham Collingridge and Richard Morris have won for their work on how memories are formed. BBC science reporter Jonathan Webb is a former neuroscientist and brings us up-to-date with the latest thinking on how we remember.Finally, grey hair and mono-brows have been all over the news this week with some follicular genetics. A team from UCL assessed the hair types of several thousand Latin Americans and cross-referenced this with their genomes to see what bits of DNA are associated with those characteristics. They found a set of gene variants - or alleles - some known to us, some new, that appear to be part of the reason we have straight hair or curly, bushy brows or mono-brows. Dr Kaustubh Adhikari from UCL is the lead author on the study.Producer: Jen Whyntie.
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Feb 25, 2016 • 28min

UK science and the EU, Sex of organs, Artificial colon, Gorillas call when eating

Britain faces a referendum on whether to leave Europe. Science, and scientists, often cross borders in collaborations, so what would the implications be for a British exit from the EU? The House of Lords Science and Technology Committee have an ongoing inquiry into how EU membership influences British science. Inside Science condenses the pertinent points. The stem cells that make up our organs 'know' whether they are 'male' or 'female', and that this sexual identity could influence how they grow and behave. Dr Irene Miguel-Aliaga, at the MRC Clinical Sciences Centre at Imperial College London, wanted to ask a very basic question: whether it is just the cells of the sex organs of a fully developed organism that 'know' their sexual identity, or whether this is true of cells in other organs too - and whether that matters. It was previously thought that non-reproductive organs are the same in both sexes, and function differently because of the differences in circulating hormones, but her new research suggests that cells know their sex.At Birmingham University, chemical engineers have built a working prototype of an artificial human colon, the first of its kind. The colon does the last bit of moving your food out of your body, mixing it, squeezing the last few nutrients and excess water out of it. The team want to use it to measure drug delivery to the colon.Talking with your mouth full is an unattractive trait, but for other, non-human, great apes it is a normal part of meal time. The noises recorded by a team at the Max Planck Institute for Ornithology are from the silverback Western lowland Gorilla. Primatologist Eva Luef explains that this humming and singing during meal time is a way of signalling without wasting valuable eating time.
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Feb 18, 2016 • 28min

Gravitational Waves, UK Spaceport, Big Brains and Extinction Risk, Conservation in Papua New Guinea

Gravitational waves were announced last week, in what may be the science discovery of the decade. The Ligo detector, the most sensitive instrument on the surface of the planet, detected the ripples given off by the collision of two black holes. Adam Rutherford puts a selection of listener questions to UCL cosmologist Dr Andrew Pontzen.In March 2015, Campbeltown, Glasgow Prestwick, Stornoway, Newquay, Llanbedr and Leuchars were shortlisted by the government as possible sites for a "cosmodrome" or spaceport. With the UK space industry worth an estimated £40 billion by 2030, various stakeholders met for the UK spaceport conference at the Royal Aeronautical Society in London to discuss the progress of the project. What would the impact be for scientists, industry and the public?Big brains have traditionally been considered an advantage. Animals with larger brains are better at using tools, working as a social group and assessing how to react to predators. But when Dr Eric Abelson cross referenced relative brain size against the mammals on the endangered list, he found something surprising. Many animals with the bigger brains are threatened within extinction. He talks to Adam about why that may be.Tim Cockerill, ecologist and adventurer, returns from Papua New Guinea to discuss how one group of indigenous people have decided to work with scientists in order to conserve and study their local environment.
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Feb 11, 2016 • 28min

Gravitational Waves Special

The universe is silent no longer - physicists at the LIGO observatory have detected gravitational waves.LIGO, the Laser Interferometer Gravitational-wave Observatory, with its giant laser beam arms totalling 5 miles across the remote Hanford desert, is the largest lab on the surface of the planet. It was constructed in the Columbia Basin region of south-eastern Washington specifically to detect gravitational waves -- ripples in the fabric of space-time. First predicted a century ago by Einstein in his theory of general relativity, gravitational waves are produced by exotic cosmic events, such as when 2 black holes collide. Scientists have hunted for them for decades with increasingly sensitive equipment. The laser beam tubes of the observatory have proved sensitive enough to detect the signal from deep space as small as a thousandth the diameter of a proton.Tracey and studio guest Dr Andrew Pontzen from UCL examine the science of gravitational waves, and how LIGO is both an eye and an ear on the motion of distant objects. They scrutinise the cutting-edge technology, which has to be of almost unimaginable sensitivity to enable detection of some of the universe's most dramatic events. Inside Science also shines a spotlight on the passion of individuals who have worked for nearly three decades on a single science experiment, inventing a whole new branch of physics in order to prove the last piece of Einstein's theory of general relativity, and to "hear" the universe in a whole new way.
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Feb 4, 2016 • 28min

UK pollinators' food, Brain implant, Holograms, Lunar 9

A study shows nectar production in UK flowers increased by 25% due to reduced pollution. Neuroscientist Dr. Phil Kennedy conducted a self-experiment with brain electrodes. Birmingham University researchers are developing cheaper holograms like holographic tattoos.
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Jan 28, 2016 • 28min

Zika, Penguins, Erratum, Fossil fish

The Zika virus is dominating the news this week. The latest data says it's been found in 21 countries so far. The symptoms are generally mild, but the possibility of a link to microcephaly has been raised in Brazil. Microcephaly is a serious condition where children are born with abnormally small heads and sometimes incomplete brain development. Trudie Lang, Professor of Global Health at Oxford University, and virologist Professor Jonathan Ball from Nottingham University discuss what we know so far.All the way from Antarctica our reporter Victoria Gill brings us the latest news about the citizen science project 'Penguin Watch'. Victoria installed new cameras with Dr Tom Hart and collected guano with Hila Levy. Gemma Clucas (Oxford and Southampton University) gives an update on what will happen with the collected data. Back in October we featured a major paper by a team of scientists lead by Dr Andrea Manica from Cambridge University. By comparing the 4500 year-old genome of a prehistoric man called Mota to other genomes from living Africans they had mapped a migration of Middle Eastern farmers back into the whole African continent. This week, colleagues identified an error in the way the original team had processed the data, thus overturning one of the key results. But the rest of the findings remain intact. Andrea talks to us about how and why science must make corrections along the path of progress.Heard a few stories about giant dinosaur fossils lately? Usually the giant A-list superstar fossils get all the attention. But according to curator Mark Carnall, about 90% of the collections are mainly uninteresting specimens. Marnie Chesterton went out to meet Mark at the Museum of Natural History in Oxford. He celebrates fragmentary fossils in his blog 'Underwhelming Fossil Fish of the Month'. Warning: Lower your expectations!Producer: Jen Whyntie Assistant Producer: Julia Lorke.
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Jan 21, 2016 • 28min

Ancient Britons' DNA, Concorde's 40th Anniversary, Giant dinosaur, New planet?

DNA expert Professor Dan Bradley discusses new research on ancient Britons' DNA, Concorde's 40th anniversary celebrated by engineer and pilot, massive dinosaur discovery in Argentina, and the hunt for a new planet in the solar system.
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Jan 14, 2016 • 28min

The 100,000 Genome Project, Stem cell doping, Nuclear waste, Dinosaur sex

Genetics expert Prof Maria Bitner-Glindzicz discusses diagnosing rare diseases using the 100,000 Genome Project. Stem cells' survival improved with 'blood paint'. Dame Sue Ion explores nuclear waste disposal challenges. Dr David Hone's research on dinosaur features for sexual selection.
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Jan 7, 2016 • 28min

El Nino Special

El Niño expert Roland Pease discusses the impacts of El Niño on global weather patterns, including floods, droughts, fires, and altered weather patterns. Experts explain the science behind how El Niño affects different regions, such as causing rains in drought-ridden California and exacerbating fires in Indonesia. The podcast sheds light on the cyclical nature and challenges of predicting El Niño events, emphasizing the environmental and human impacts of these natural phenomena.

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