BBC Inside Science

The Bovine TB Strategy Review has just been released. It contains a review of the science and offers advice and guidance to Government ministers on how to eradicate this costly and hard to manage disease in cattle. Controversially it does not include the results from the on going badger culling trials in the West of England and it states that the majority of disease transmission is from cow to cow. But it addresses the efficacy of skin TB tests and repeatedly states that the long-term aim is to end culling badgers and moving to vaccination or other non lethal methods to control the disease reservoir in wildlife. Professor Rosie Woodroffe at the Institute of Zoology, who ran the Randomised Badger Culling Trials in 2007, thinks the report is mostly a good thing. She praises the advice to find alternatives to killing British wildlife, but explains to Adam Rutherford that trialling vaccinations for badgers after culling could be problematic. Monitoring the health of estuarine and coastal water ecosystems usually relies on the expensive and time-consuming practice of catching fish to get a view on the health of entire ecosystem. New methods are starting to be used called Environmental DNA sampling, using DNA barcoding techniques. As everything sheds fragments of DNA into the environment, by sampling water or sediment, you can use High Throughput DNA analysis, using special probes to pull out and identify the species you want. It’s a lot quicker and cheaper, but you still have to deal with problems of collection, filtration and contamination. But Professor of Conservation Genetics, Stefano Mariani at the University of Salford, has found an even better way. He's recruited the European brown Shrimp, which eat everything, are found everywhere and can do all the filtering and storing of the DNA for him. All Stefano has to do is catch the shrimp and analyse their stomach contents to get a picture of what is in the environment.PhD student at Sheffield University, Rory Cooper explains to Adam how mathematical patterns that Alan Turing worked on late in his career are found in abundance in the natural world. The genetic mechanisms of switching on cellular processes that lead to feather or hair emergence have now been found in the formation of shark scales. The pattern relies on genes to switch on a function, such as feathering, but diffuse out to surrounding cells and switch the function off, leading to a uniform, spaced out pattern. As shark species split off from other vertebrates around 420 million years ago, it therefore proves that Turing’s pattern is recycled through other vertebrates. Producer: Fiona Roberts

What could be the oldest figurative cave paintings in the world have been found in a cave complex in remote Borneo. A reddish orange depiction of an animal that could be a Banteng (wild cattle found in the region) is at least 40,000 years old. Humans are now the greatest force in shaping the surface of the Earth. We now move more than 24 times as much rock, rubble and sediment than all the world’s rivers. Dr Anthony Cooper of the British Geological Society has been weighing this anthropogenic global force. Closer to home, Adam Rutherford speaks to Professor Colin Waters at the University of Leicester, about the weight of human-created rubble he’s found under the City of London. When the new polymer £50 note is introduced in around a year’s time, it’ll have a scientist on the reverse. Industrialist Matthew Boulton and engineer James Watt will step aside for a British scientist nominated by the public. Sarah John, Chief Cashier at the Bank of England, explains the rules to Adam and science experts, Emily Grossman and Alice Bell debate the merits of some of the more popular front runners.

Potholes are one of the biggest frustrations to any road-user, but why do they keep occurring? Following Philip Hammond’s announcement of £420 million for councils to tackle potholes, Malcolm Simms, Director of the Mineral Products Association’s Asphalt & Pavement group, explains how potholes form and why they continue to occur. Alvaro Hernandez of Nottingham University chats to Marnie about new solutions he is investigating to improve our roads and reduce the number of potholes. Roland Pease meets John Able and Professor Simon Potts, to discuss the value of ‘big data’ – in this case, for honeybees. Using a ‘buzz box’ to detect conditions inside and out of the beehive, this data can be transmitted to the cloud and used to keep track of beehive health. This is termed the ‘internet of hives’ and provides a huge amount of high quality data to discover the key indicators of beehive health. Back in the 1980s, the world discovered that CFCs were destroying the ozone layer, which protects the earth, and us, from being fried by the sun’s rays. The 1987 Montreal Protocol banned the use of CFCs, and as we stopped emitting them, the ozone layer started to recover. But there are other gases like carbon tetrachloride that destroy the ozone layer and are also restricted. But Dr Matt Rigby, an atmospheric chemist from Bristol University, has been discovering that there are still sources of carbon tetrachloride. Testing for illicit drugs usually needs a blood or urine sample, but now it can be done from a sweaty fingerprint. And not only on a living suspect, but on a corpse. Adam Rutherford speaks to the developer of this smart chemistry , University of East Anglia’s David Russell.

How might Brexit affect UK Science? Why is feeding a 'last resort' antibiotic to farm animals not a good idea? Why is space probe Bepicolombo going to Mercury? Adam Rutherford is your host.This week, leading British and European scientists wrote to the British Prime Minister and European Commission President. They expressed their concerns about the potential impact if there is a no-deal departure by the UK from the European Union. We hear from one of the signatories Professor Venki Ramakrishnan, President of the Royal Society and from UK Science Minister Sam Gyimah.Roland Pease reports on the use of the medically valuable last-resort antibiotic, colistin, as a growth promoting substance in agricultural livestock feed in India. He speaks to infectious disease consultant Abdul Ghafur in Chennai, India and microbiologist Tim Walsh at Cardiff University.The space probe Bepicolombo has begun its 7 year voyage to the planet Mercury. Suzie Imber of the University of Leicester and David Rothery of the Open University tell Adam why the journey will take so long and why Mercury is such an intriguing planet, worthy of exploration by this new probe.

How far back can we trace the ancestry of dogs? For just how long have they been following us around? The answer is for a very long time - long before humans settled down and developed societies. Scientists in France have been looking at ancient dog DNA to try and work out whether people tamed and domesticated local dogs as they migrated across the planet, or brought dogs with them. The answer tells us much about the relationship - or rather lack of it, between early farmers and the hunter gathers they replaced throughout Europe. And how many Bosons can you fit in a rocket? As they are rather small particles the answer will be quite a lot, but a team from Germany has succeeded in making a form of mater known as the Bose Einstein Condensate in a small rocket which they launched into the Earth’s upper atmosphere. Potentially the success of their experiment could lead to new ways of detecting gravitational waves in space. Back on earth a group of ‘A’ level students have been looking at or rather listening to data from space, and published a scientific paper on their observation of a solar storm. In a unique partnership with university physics researchers, information on electromagnetic waves around our planet has been turned into audible data. The keen ears of the students identified events that had not previously been detected. And how incriminating is your washing machine? Digital forensics, the unpicking of the data trails on our digital devices, from phones to TV tuners, even baby monitors and washing machines are now playing a part in criminal investigations, not just cases involving online fraud or cybercrime, but any investigation looking at what suspects were doing and when. A digital trail can act as evidence for time and place.

Adam Rutherford speaks to Dr Tamsin Edwards, a lecturer in Physical Geography at Kings College London and a lead author for the latest IPCC report. Dr Edwards describes what happens in the making of the report, including the summarising of the wealth of scientific literature available into an understandable document for the policy makers.Cairngorms National Park in Scotland is part of an ambitious project to restore the habitat to its former natural state. Four organisations have joined together as the 'Cairngorms Connect’ project – Scottish Natural Heritage, the Royal Society for the Protection of Birds, Wildland Limited and Forest Enterprise Scotland. Graeme Prest of Forest Enterprise Scotland explains how the project team will start to restore the habitat.The grass pea is a resilient and highly nutritious legume but it contains varying level of toxins. Marnie Chesterton visits the John Innes Centre in Norwich to meet the researchers working on making the grass pea less poisonous, which could aid food security, particularly in sub-Saharan.The Sun is technically a G-type main sequence star, which means it’s a giant continuous nuclear fusion reaction plasma, spewing out extremely dangerous matter and energy in every direction, and when it hits the Earth, this can cause all sorts of problems. Adam visits the Science Museum in London to meet Harry Cliff, a physicist and curator of a new exhibition: ‘The Sun: Living With Our Star’, which explores our relationship with the closest star to earth. Adam also finds out from Professor Chris Scott of Reading University about a citizen science project called Protect our Planet from Solar Storms.

Adam Rutherford reviews this year's Nobel science prizes, and talks to Professor Venkatraman Ramakrishnan, a 2009 laureate and president of the Royal Society, about the experience of being tipped as a Nobel winner. This can included a stressful condition known as Pre-Nobelitis and having unidentified Scandinavians turn up in the audiences of your scientific talks.The Japanese space probe Hayabusa 2 dropped an exploratory robot onto the surface of the asteroid Rguyu early on Wednesday morning. The autonomous probe is called MASCOT. With 16 hours of battery life, it landed at one spot on the asteroid's southern hemisphere, took a slew of data and then jumped to another location for more image-taking, temperature and magnetic measurements and chemical analyses of the rocks. MASCOT project manager is Dr Tra-Mi Ho of the German Space Agency.A critical meeting of the International Panel on Climate Change is underway in South Korea. Scientists and government representatives aim to finalise a policy road map to limit global warming to a 1.5 degree C increase by the end of the century. BBC News environment correspondent Matt McGrath is reporting from the meeting and explains why 1.5 degree C and not 2 degrees is the new preferred target for many scientists and nations. But will scientists and policy makers from around the world see eye to eye?Physicist Helen Czerski provides Adam with a final report at the end of her 8 week expedition at the North Pole which aimed to explore the interactions of water, ice, atmosphere and life in shaping Arctic weather and climate. The adventure ended with a crunch and the loss of thousands of pounds worth of scientific kit.Producer: Andrew Luck-Baker

Japan’s Hayabusa-2 spacecraft has arrived after more than a three year journey at the Ryugu asteroid which is just over half a mile long. It has successfully sent probes onto the surface and is sending pictures back to Earth. Gareth Mitchell discusses the achievement with BBC Science Correspondent Jonathan Amos. A hundred years ago, the 1918 flu pandemic killed between 50 and 100 million people worldwide and infected around half a billion. Seasonal flu accounts for about 650,000 deaths per year. As this year’s flu season approaches, there are new insights into how the influenza virus causes disease and why some strains like the 1918 one (a subtype of the avian strain H1N1) are so deadly compared with the seasonal kind. In the most serious cases, there’s an extreme immune reaction in the lungs, and people can effectively suffocate. The latest research from the universities of Cambridge and Oxford has uncovered a molecule that might be behind that immune overreaction. Dr Aartjan te Velthuis explains the findings and the implications for novel treatments. The massive bombing raids on cities in World War Two lead to terrible human tragedy, Now a historian and a physicist have been looking at how shock waves from some of the major bombing over Berlin caused the upper atmosphere above Slough to wobble. Specifically they’re interested in the layer eighty to a thousand kilometres up that reflects radio waves, the ionosphere. Historian Patrick Major and meteorology expert Christopher Scott, both professors at the University of Reading, tell Gareth about their collaboration and how monitoring changes in the ionosphere today can reveal both man made and natural explosive events. And Adam Rutherford talks to Professor Sarah-Jayne Blakemore of UCL about her book, Inventing Ourselves: the Secret Life of the Teenage Brain, the last on this year's shortlist for the Royal Society Insight Investment Science Book Prize.

The Science Gallery London at Kings College London, right under the Shard, is a brand new venue for the collision of art, science and culture, and its opening exhibition is called Hooked, a series of installations and works by people who have experienced addiction. Adam Rutherford explores the neuroscience, the psychology and the epidemiology of addiction; what the latest research says about what addiction is, and how that can help us treat people experiencing addiction. He discusses these questions with psychologist Dr Sally Marlow and neurologist Professor Mitul Mehta who are both at Kings College and have been involved in the exhibition, and Dr Suzi Gage from Liverpool University who studies the epidemiology of addiction. He also talks to the curator of Hooked, Hannah Redler Hawes, and to two of the Science Gallery Young Leaders, Elly Magson and Mandeep Singh, who show him a couple of the exhibits.

A new discovery of abstract symbolic drawings on a rock has been found in the Blombos Cave, about 300 km east of Cape Town in South Africa. The fragment - which some say looks a bit like a hashtag - puts the date of the earliest drawing at 73,000 years ago. As archaeologist Chris Henshilwood tells Adam Rutherford, the discovery is a "a prime indicator of modern cognition" in our species.Nearly half the human genome contains genes that regulate what your organs should be doing at a specific time of day, This has enormous potential importance to the efficacy of drugs - what time of day you take them could be a real issue. John Hogenesch from Cincinnatti Children's Hospital has been studying the genes that cycle with our daily lives. His new database of cyclic genes could help plan the best timing for a host of therapeutic interventions Physicist Helen Czerski has been in the Arctic for the last five weeks, aboard the Swedish research vessel and ice breaker Oden. As the expedition comes to a close we hear about the team's attempts to elucidate the driving forces behind the unusual weather patterns around the North Pole. Inside Science has been profiling authors shortlisted for the prestigious Royal Society science book prize. This week it's mathematician Hannah Fry's new book, Hello World: How to be human in the Age of Machines. You can hear extracts from it on Book of the Week on Radio 4 all this week too.Producer Adrian Washbourne.