BBC Inside Science

Base editing is a technique for substituting the building blocks of DNA. It has only been around for a few years, so its use to apparently cure cancer was all the more remarkable, as BBC Health Correspondent James Gallagher tells us.We take a trip down the river Wye with ecologist Steve Ormerod who tells us why the river is a microcosm for some of the global issues being discussed at the UN Biodiversity summit in Montreal. BBC Environment Correspondent Victoria Gill gives us the latest on the state of negotiations there.And the current surge in infections associated with the streptococcus bacteria has led to deaths in a few cases. It is usually a seasonal infection, worse in the spring. We ask microbiologist Dr Claire Turner from Sheffield University why we seem to be seeing a surge of infections now and her research on strep vaccine targets.BBC Inside Science is produced in collaboration with the Open University.

The UN Convention on Biological Diversity summit, currently taking place in Montreal Canada, intends to develop ways of reducing the global loss of biological diversity by drawing up a series of international commitments to help humanity to live more harmoniously with nature. The scientific evidence paints a grim picture of species decline and extinction, pollution and destruction of natural habitats. The aim of the meeting is to find ways to stop and even reverse such decline. We meet leading figures involved in the negotiations, including:Elizabeth Mrema, the Executive Secretary of the UN Convention on Biological DiversityInger Andersen Executive Director of UN Environment ProgrammeIndigenous leaders Viviana Figueroa and Lakpa Nuri Sherpa And scientists Professor Sandra Diaz from the University of CordobaDr Marla Emery Scientific Advisor with the Norwegian Institute for Nature Research. BBC Inside Science is produced in partnership with the Open University.

For a week at the beginning of December 1952, London was under a blanket of deadly smog. As a result, the Clean Air Act came into force a few years later banning smoky sulphurous fuels. However air pollution researchers are now concerned that rising emissions from wood burners may be undoing many of the gains from the Clean Air Act. We hear from Dr Gary Fuller, air pollution scientist at Imperial College London and author of The Invisible Killer, the Rising Global Threat of Air Pollution and How We can Fight Back. We also discuss emissions we can’t see, bacteria and even microplastics which are now present in the air. Catherine Rolph from the Open University tells us where we might find them.And we reveal the winner of the Royal Society Insight Investment Science Book Prize. You can find interviews with all the shortlisted authors in our previous programmes.BBC Inside Science is produced in partnership with the Open University.

The UK has the opportunity to access European science funding. However disagreements over the Northern Ireland protocol are preventing the UK from joining the multi billion pound Horizon Europe project which funds scientific partnerships between European institutions. BBC Science correspondent Pallab Ghosh has been following developments. Spending time in green spaces has been linked to mental and physical health benefits. But just how green is your nearest city centre? New research has ranked urban centres in the UK based on their ‘greenness’ and Jake Robinson, from Flinders University in Australia, revealed who came out on top. We hear about initiatives to enhance ‘greenness’ including the citizen-science led GroundsWell programme with Elly King, from the University of Liverpool, and living walls with Brenda Parker, at UCL. And from the Royal Society science book prize, we’re talking sex and gender with primatologist Frans De Waal whose new book is entitled Different: What Apes Can Teach Us About Gender.

As the COP27 environment summit draws to a close we look at some of the issues still to be resolved. BBC Environment correspondents Victoria Gill and Georgina Rannard join us from the meeting. And we head to the houses of parliament in the company of a group of teenagers who are putting their concerns over climate change to a panel of politicians. Julia Ravey went to meet them. We hear from author Nick Davidson about how the discoveries of 3 unlikely characters in the 19th century formed the basis of geological science. His book The Greywacke is shortlisted for the Royal Society Science Book Prize. And a scientific analysis of the Winchcombe meteorite gives us some clues as to the possible origins of life on earth. Natasha Stephen from Plymouth University is one of the many scientists who analysed the composition of the rock fragments.

One key issue on the agenda at the COP27 environment summit in Egypt is how to fund damage from the effects of man made climate change. Often the effects of climate change are felt the strongest in countries least responsible for creating the emissions. This year we’ve seen a range of extreme weather events including drought and flooding which scientists have attributed to man-made climate change. The idea of providing funding for such human-induced disasters has long been discussed informally at COP summits. Finally the issue is formally on the table. It's fraught with diplomatic difficulties, not least over who should pay and how much. We discuss some of the issues in getting a solution on this initiative known as ‘Loss and Damage’ with contributions from Josh Gabbatiss from the website Carbon Brief, Rachel Kyte, the Dean of Tufts University, Linnéa Norlander Assistant Professor of human rights and sustainability at the University of Copenhagen and Hyacinthe Niyitegeka, coordinator of the Loss and Damage Coalition. And we look at methane with Drew Shindell, professor of Climate science at Duke University and Author of the UN Environment Programme’s Global Methane Assessment, who tells us a reduction in methane could give us a quick fix in terms of efforts to stabilise global temperatures.

A new study published in the British Medical Journal suggests monkey pox might be passed from person to person before symptoms show. Esther Freeman, Assistant Professor of Dermatology at Harvard Medical School and Director of Global Health Dermatology at Massachusetts General Hospital, has been following the current wave of transmission and gives us her analysis of this latest finding, The COP 27 climate summit kicks off next week. To discuss some of the issues we are joined by Simon Lewis, Professor of global change science at University College London and Swenja Surminski, Professor in Practice at the Grantham Research Institute and a member of the UK's Committee on Climate Change. Mark Miodownik, the UCL Professor of Materials & Society, tell us the results of his citizen science project looking at composting plastics.And from the short list for the Royal Society Insight Investment Science Book Prize, we hear from Professor Rose Anne Kenny on her book Age Proof: The New Science of Living a Longer and Healthier Life.

New recordings featuring the voices of 53 species of turtle, caecilian and tuatara previously thought to be silent have illuminated the evolutionary origins of vocal communication. Gabriel Jorgevich-Cohen a PhD student at the University of Zurich has travelled the world collecting recordings and summarised his findings in Nature Communications this week. He spoke to BBC science correspondent Georgina Rannard who explains his findings, what they mean, and shows us some of her favourite turtle sounds. What was it like to advise the government during the height of the pandemic? How soon did experts realise the colossal impact Covid would have? Were mistakes made? The latest in our series of interviews with those shortlisted for the Royal Society Insight Investment Book prize, Vic sat down with co-authors Sir Jeremy Farrar and Anjana Ahuja to talk about their book Spike: the Virus vs the People. Anne-Claire Fabre Assistant Professor at the University of Bern and Curator of mammals, Natural History Museum Bern turns her scientific curiosity toward a surprising and perhaps perturbing behaviour in one of her research animals as she spoke to us about her paper published in the Journal of Zoology this week. Whilst investigating the Aye Aye, a nocturnal primate with two long thin fingers Anne-Claire witnessed the creature putting them to good use picking its nose and went on to uncover a big gap in our understanding of this icky behaviour. Presenter Victoria Gill Producer Emily Bird

Recorded in front of an audience at Bradford’s National Museum of Science and Media, we’re delving into the next 100 years of broadcasting, examining the science and technology behind what we’ll watch and listen to. And what the seismic technological shifts mean for all of us. Victoria Gill is joined on stage by four people who give us an audio tour of that media future. Lewis Pollard the curator television and broadcast at the museum.Dr Karen Thornton programme leader teaching film and television production at the University of Bradford.Bill Thompson technology commentator. Gemma Milne writer and researcher interested in how science and technology impacts all of us. And author of Smoke and Mirrors - how hype obscures the future and how to see past it. BBC Inside Science is produced in partnership with the Open University

Avian or bird flu is normally seasonal, disappearing as migratory birds leave for winter. However a new strain which seems to spread more easily between wild birds and into poultry has led to the deaths of far more birds than usual. David Steel, Nature Reserve Manager on the Isle of May relates his observations of the effects on seabirds. And Nicola Lewis, Director of the Worldwide Influenza Centre at the Francis Crick Institute tells us why this particular stain is so severe.Climategate was a strange kind of scandal, based entirely on misinformation pushed by climate change deniers. In his new book Hot air, shortlisted for the Royal Society Insight Investment science book prize, Climate scientist Peter Stott assess the impact of their campaign. Pong was a very basic video game developed in the 1970s, now Australian researchers have trained human brain cells in a dish to play the game, Dr Brett Kagan from Cortical Labs explains why.