Science Friday

Science Friday and WNYC Studios
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Oct 15, 2021 • 47min

Native Biodata, Indigenous Carbon Resistance, COVID Boosters Next Steps. Oct 15, 2021, Part 1

More Boosters, For More People This week, an FDA advisory committee met to pore over data and debate the role of COVID vaccine boosters. And on Thursday, they voted to recommend Moderna boosters for older Americans, as well as people in certain at-risk groups. This recommendation came just a few weeks after the FDA authorized a Pfizer booster for similar individuals. The recommendations of the panel regarding boosters for Moderna and Johnson & Johnson vaccines, as well as the idea of mixing and matching different vaccine and booster types, will now go to FDA officials. The CDC will also weigh in. Amy Nordrum, commissioning editor at MIT Technology Review, joins Ira to talk about the vaccine meeting and other topics from the week in science—including the FDA authorization of an e-cigarette, efforts to map the brain, mysterious radio signals from space, and a mission to explore asteroids near Jupiter.   Indigenous-Led Biology, Designed For Native Communities Monday was Indigenous Peoples’ Day here in the United States: a holiday to honor Native Americans and their resilience over many centuries of colonialism. Due to a long history of discrimination, Native Americans face stark health disparities, compared to other American populations. Illnesses like chronic liver disease, diabetes, and respiratory diseases are much more common in Native communities. This is where the Native BioData Consortium (NBDC) comes in. It’s a biobank, a large collection of biological samples for research purposes. What sets this facility apart from others is its purpose—the biological samples are from indigenous people, and the research is led by indigenous scientists. This is important, say the founders, because for too long, biological samples from Native people have been used for purposes that don’t benefit them. Joining Ira to talk about the importance of having a biobank run by indigenous scientists are three foundational members of the project: Krystal Tsosie, co-founder and ethics and policy director of the NBDC and PhD candidate in genetics at Vanderbilt University, Joseph Yracheta, executive director and laboratory manager of the NCDC, and Matt Anderson, assistant professor of microbiology at Ohio State University and NCDC board member.   Indigenous Activists Helped Save Almost A Billion Tons Of Carbon Per Year This summer, Science Friday and other media outlets covered the protests against an oil pipeline project in northern Minnesota, where Canadian company Enbridge Energy was replacing and expanding their existing Line 3 infrastructure. Native American tribes in Minnesota—whose lands the pipeline would pass through and alongside—organized protests, direct action, and other resistance against the project. The pipeline was completed, and began moving tar sands oil at the beginning of October. But the protests and their non-Native allies drew arrests, news coverage, and social media attention to the debate over continued drilling of fossil fuels. Before Line 3, there were protests at the Dakota Access Pipeline, which was completed against the wishes of the nearby Standing Rock Sioux Tribe, and the Keystone XL pipeline, which President Biden ultimately cancelled after objections and lawsuits from two Native American communities in Montana and South Dakota. So far, the Arctic National Wildlife Refuge has remained un-drilled, despite multiple attempts, with help from vocal opposition by Alaska’s Gwich’in people. A new report from two advocacy groups does the math on how much carbon dioxide or other greenhouse gas emissions these cancelled or delayed projects would have emitted in the last 10 years. According to their calculations, Indigenous resistance to pipelines and other fossil fuel projects has saved the U.S. and Canada 12% of their annual emissions, or 0.8 billion tons of CO2 per year. Ira talks to the co-authors, Dallas Goldtooth of the Indigenous Environmental Network, and Kyle Gracey from Oil Change International, about the value of tallying these emissions in the fight to prevent future oil projects. Plus, why Native American protesters and their allies deserve credit for keeping fossil fuels in the ground—and the bigger environmental justice issue of pipeline projects alongside Native land. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Oct 8, 2021 • 57min

Air Conditioning, Face Recognition Neurons. Oct 8, 2021, Part 2

The Hot And Cold Past Of The Air Conditioner In the Northeast, the leaves have started changing colors, heralding the season of pumpkins, sweaters, and the smell of woodsmoke. But in some parts of the country, the heat hasn’t let up. In cities like Dallas, Phoenix, and Miami, temperatures were up in the high 80s and low 90s this week—and with climate change, the U.S. is only getting hotter.  But humans have come up with an ingenious way to keep the heat at bay: air conditioning. Widely considered one of the greatest engineering achievements of the 20th century, the technology has transformed how and where people live—and it’s prevented countless deaths. But it comes at a cost, and if we’re going to keep up with a warming climate, we’re going to need some other tricks to stay cool.  Like what you hear? Dive deeper with some of the sources we turned to while reporting.      See A Familiar Face? Thank These Brain Cells What happens when you see a familiar face? Light reflected from the face enters your eye, is focused onto the retina, and a signal travels up your optic nerve. But what exactly goes on in your brain after that is still somewhat mysterious.   Recently, researchers reported in the journal Science that they had identified a group of brain cells that seem tuned to respond only to familiar faces. The theory is that the specificity of those neurons helps to speed up processing of potentially important visual information. The work was done in monkeys, but the researchers are currently trying to identify similar brain structures in people.   Sofia Landi and Winrich Freiwald, two of the authors of the report, join Ira to talk about the research, and what it may tell us about how the brain and memory are organized.  Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Oct 8, 2021 • 47min

State Of COVID And Antiviral Pill, Future Pandemics. Oct 8, 2021, Part 1

First Malaria Vaccine Is Approved by WHO The malaria parasite is one of the world’s deadliest infectious diseases, killing on average about 500,000 people per year—half of them children under the age of 5, nearly all of them in sub-Saharan Africa. Now, the World Health Organization has finally approved RTS,S or Mosquirix, the first vaccine against Plasmodium falciparum, which is the most deadly strain of the parasite. The vaccine has already been administered via a pilot program to 800,000 children in Kenya, Ghana, and Malawi, and in clinical trials showed an efficacy rate of about 50% against severe disease. WNYC’s Nsikan Akpan explains this and other stories, including a climate change-linked Nobel Prize in physics, controversy over the naming of the James Webb Space Telescope, and a new surveillance method that uses only the shadows you cast on a blank wall. Will Improved Testing And New Antivirals Change The Pandemic’s Path? Late last week, the pharmaceutical company Merck released data on a new antiviral medication called molnupiravir—a drug taken as a course of pills over five days that the company said was dramatically effective at keeping people with COVID-19 out of the hospital. In a press release, the company said that trial participants on the medication had a 50% lower risk of hospitalization or death compared to people getting the placebo. And while eight people in the placebo group died during the trial, none of the people getting the new drug did. However, the full data from the trial has yet to be released—and the medication must still go through the FDA approval process before it can be used. Matthew Herper, senior writer at STAT covering medicine, joins Ira to talk about the drug and what questions remain. Then, infectious disease specialist and epidemiologist Céline Gounder discusses other recent coronavirus news—from a government plan to spend a billion dollars on at-home testing to recent data on the Delta variant, including projections of what might happen next. Preparing For The Next Pandemic Needs To Start Now The United States has a long history of public health crises. For many, our first pandemic has been COVID-19. But long before the SARS-CoV-2 virus arrived, HIV, measles, and the flu all left a lasting impact. As a wealthy country, you may think the United States would be prepared to deal with public health crises, since they happen here with a degree of regularity. However, that’s not the case. The longstanding issues that left the country vulnerable to COVID-19 are explored in a recent article from The Atlantic, called “We’re Already Barreling Toward the Next Pandemic.” The piece was written by science writer Ed Yong, who won a Pulitzer Prize last year for his coverage of COVID-19. Ira speaks to Ed and Gregg Gonsalves, global health activist and epidemiologist at Yale, about the country’s history of public health unpreparedness, and what needs to happen to be ready for the next pandemic.   Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Oct 1, 2021 • 47min

A Century Of Science, Book Club: Rising, Charismatic Creature Update. Oct 1, 2021, Part 2

Looking Back On A Century of Science In 1921, the discovery of radium was just over 20 years in the past. And the double helix of DNA was still over thirty years in the future. That year, a publication that came to be the magazine Science News started publication, and is still in operation today. Editors Nancy Shute and Elizabeth Quill join Ira to page through the magazine’s archives, with over 80,000 articles covering a century of science—from the possibilities of atomic energy to discussions of black holes, to projections of the rise of the avocado as a popular fruit. There are mysteries—are spiral nebulae other universes? And there are missteps, like the suggestion that the insecticide DDT should be incorporated into wall paint.     When The Water Comes The Science Friday Book Club is kicking off for fall. Producer Christie Taylor joins in a conversation with Elizabeth Rush, author of Rising: Dispatches from the New American Shore. They talk about the surprisingly fascinating science of coastal wetlands, and their role in protecting communities from sea level rise—plus how communities themselves, from Staten Island to southern Louisiana, are responding to rising seas and flooding. For the full rundown, excerpts, and more, check out our main Book Club page.   Who Will Sweep The Charismatic Creature Carnival? Our Charismatic Creature Carnival is coming to a close. Over the last month, SciFri has celebrated six overlooked or unfairly maligned species that deserve a chance under the spotlight. And now, out of our three semifinalist creature candidates, there can only be one winner. Will it be the colorful, tiny, but mighty mantis shrimp? Or perhaps the adaptable, dramatic opossum? Or will the endangered shoebill stork, with its prehistoric look, come out on top? The choice is up to our listeners: vote here.   Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Oct 1, 2021 • 47min

Primate Parasites, Spider Mating Songs, Spotted Lanternfly. Oct 1, 2021, Part 1

Healthcare Is Hard Enough to Get. If You’re A Trans Youth, It’s Even Harder Healthcare can be difficult to access for anyone—that’s been made clear during the COVID-19 pandemic. But for transgender youth, the barriers are exponentially higher. A new study from the journal JAMA Pediatrics shows that trans youth don’t get the care they need because of a variety of obstacles. Those range from laws that prevent them from advocating for themselves, to stigma from doctors. Joining Ira to talk about this story and other big science news of the week is Sabrina Imbler, science reporting fellow for the New York Times based in New York City. Ira and Sabrina also discuss the massive undertaking of COVID-19 testing in school districts, and the impacts ivermectin misinformation is having on the livestock and veterinary industries.   See A Spotted Lanternfly? Squash It! If you live in Pennsylvania or any of its surrounding environs, you’ve probably seen a really interesting looking bug in the past few years: the spotted lanternfly. Around this time of year, it’s in its nymph stage. But when fully grown, these lanternflies sound a little like the joke—they’re black and white and red all over. They’ve also got spots, as their name suggests. The charming news about how interesting they look is offset by the bad news: They are an invasive species. And they frighten crop farmers because they have a taste for just about anything, and a fondness for grapes, which could have dramatic economic consequences. Many states have a unified stance on what to do if you spy a spotted lanternfly—stomp them out. But is that an effective way to stop their spread? Joining Ira to chat about stomping techniques and lanternfly biology is Julie Urban, associate research professor in entomology at Penn State University, in State College, Pennsylvania.   As Primates Go Extinct, So Do Their Parasites, Upsetting Ecosystems As of 2017, more than half of primate species—that’s apes, monkeys, lemurs, and our other relatives—were considered at risk of extinction. While the loss of these animals would be its own ecological crisis, this is causing another wave of die offs: the parasites that live on those primates, many of whom are specially adapted to live on just one species for their entire lives. That includes fungi and viruses, as well as the more grimace-inducing parasites like lice and intestinal worms. Producer Christie Taylor talks to Duke Lemur Center researcher James Herrera, the first author on new research that found if endangered primates do disappear, nearly 200 species of primate parasites might also. They talk about why that loss could have consequences—not just for dwindling primates, but also for us.   The World According To Sound: How Spiders Shake Things Up For Love Amorous arachnids sing to their lovers without making a sound. Instead, they like to shake things up. Spiders aren’t powerful enough to vibrate the air, the way actual singing does. Instead, they use the ground. Male spiders send vibrations down their legs, and into whatever they’re standing on. Nearby females “hear” the song vibrating up their legs. Humans can’t hear these spider songs with our ears, but we can listen to them with the help of a laser doppler vibrometer. This instrument can make non-contact vibration measurements of a surface. It shoots a laser beam at a particular surface, and depending on how much that surface moves, it can then measure the frequency and amplitude of the vibration, based on the Doppler shift of the reflected laser beam. Hear an example of these lovelorn spiders on The World According to Sound, a live audio show, online listening series, and miniature podcast that focuses on sound, not story. Producers Chris Hoff and Sam Harnett create intentional, communal listening experiences as a way to “reclaim autonomy in a visually dominated world that is increasingly fracturing our attention.” The spiders in this piece were recorded by researchers in Damian Elias’s lab at UC Berkeley. This recording is part of their next listening series, an immersive listening party where audiences from all over the globe will be invited to experience a world of sound together, beginning in January 2022. You can get a ticket to the series here.   Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Sep 24, 2021 • 48min

Nuclear Plant Decommissioning, Fauci Kid’s Book, Pigeon Vs Shoebill. Sept 24, 2021, Part 2

Pilgrim Nuclear Power Plant To Say Goodbye To Its Radioactive Waste Just before Thanksgiving, the Pilgrim Nuclear Power Plant in Plymouth is expected to reach a historic milestone. All the radioactive fuel that generated electricity—and controversy—for nearly half a century will finally be removed from the reactor building. It will be stored outside in special steel and cement casks. The rare occasion will be celebrated by both supporters and opponents of the plant. But as the decommissioning of Pilgrim proceeds, concern over the long-term safety of the highly radioactive waste continues. Even though Pilgrim Nuclear Power Plant stopped producing electricity two years ago, there are still armed guards in watchtowers, surveillance cameras spread over the site, mazes of barbed wire fences and concrete vehicle barriers.  Bruce Gellerman, a senior reporter at WBUR in Boston, Massachusetts, explains what the decommissioning process has been like and the future of nuclear power in the Northeast.     Dr. Fauci’s Life Illustrated In A New Book For Kids Dr. Anthony Fauci became a household name at the beginning of the COVID-19 pandemic. Now, he’s the subject of a children’s book too: Dr: Fauci: How a Boy From Brooklyn Became America’s Doctor. The book takes us back to Fauci’s childhood filled with games of baseball in the streets of Brooklyn, bike rides to deliver medications for his family’s pharmacy, and his long history of asking questions about how the world works. Author Kate Messner talks to Ira about the surprises she found in Fauci’s life story, the value of showing kids that scientists were once children too, and why curiosity is such an important value to teach children.     A Charismatic Match-up Between Two Feathered Friends It’s the third and final matchup of this fall’s Charismatic Creature Carnival, our celebration of six overlooked, and often unfairly maligned, species that deserve a chance under the spotlight. Our audience submitted the carnival candidates, but only one will be crowned the very first inductee into the Charismatic Creature Corner Hall of Fame. This week, our match-up is between two fabulous, feathered creatures: the pigeon and the shoebill stork. Defending the pigeon is Elizabeth Carlen, postdoctoral research fellow at Washington University in St. Louis. Representing the shoebill stork is Judith Mirembe, shoebill researcher and chair of Uganda Women Birders based in Kampala, Uganda.  Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Sep 24, 2021 • 47min

Two Climate Change Bills, COVID Vaccine Boosters. Sept 24, 2021, Part 1

Ice-Hunting Lunar Rover Robot Gets A Landing Site This week, NASA announced that it had selected a destination for a planned robotic lunar rover called VIPER, the Volatiles Investigating Polar Exploration Rover. The mission is planned for launch in 2023, and will rove about the Moon’s south pole, mapping the location and concentration of water ice deposits. The plan is for a commercial spaceflight mission to deliver the rover to a spot near the western edge of the Nobile Crater at the Moon’s south pole. Sophie Bushwick, technology editor at Scientific American, joins Ira to talk about the mission and other stories from the week in technology and science—including tiny airborne micro-machines, an upcoming voyage for the James Webb Space Telescope, and the discovery of ancient kids’ handprints that could be the world’s oldest-known art.   Congress Is Considering Two Climate Change Bills. What’s In Them? President Biden has made many promises about slowing climate change. During his campaign, he pledged to bring the United States’ energy sector to zero carbon emissions by 2035. On Earth Day this year, he pledged to reduce total U.S. greenhouse gas emissions by 50% by 2030, and by 100% by 2050. But the key policy changes that will help the country get there remain pending as the relevant bills continue to make their way through Congress. The first is an infrastructure bill that would pledge billions toward cleaner transit and resiliency projects in disaster-stricken communities. But that measure is tied intricately with the fate of a second, $3.5 trillion budget bill that would direct billions of dollars to incentivize coal and natural gas-burning utilities to switch over to renewable energy. If both are to pass without substantial changes, they rely on consensus among the narrow majorities of Democrats in the Senate and the House—neither of which is guaranteed. New York Times reporter Coral Davenport walks through what’s in the bills, and why so much is still up in the air even after a summer of climate-driven disasters.   Behind The Booster Battle Update 9/24/2021: This week, CDC director Rochelle Walensky overruled the recommendations of an advisory panel and authorized a third dose of the Pfizer COVID-19 vaccine for the elderly and certain “high risk” individuals, mirroring an earlier FDA decision. In late August, President Biden had said that COVID-19 vaccine booster shots might soon be on the horizon for many Americans. In late August, President Biden said that COVID-19 vaccine booster shots might soon be on the horizon for many Americans. But last Friday, an FDA advisory committee voted to recommend booster doses only for people over age 65—and this Wednesday, the FDA authorized Pfizer boosters for use in the elderly and “high risk” individuals. In the republished article (which you can read on sciencefriday.com) from September 16, written before the FDA review, Kaiser Health News’ Arthur Allen and Sarah Jane Tribble examine the backstory behind the debate over boosters, and how leaders from the NIH got out in front of FDA and CDC recommendations. Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Sep 17, 2021 • 48min

Endemic Diseases, Insects and Light, Opossum vs Aye-Aye. Sept 17, 2021

Nighttime Streetlights Are Stressing Out Urban Insects As insect populations—including bees, moths, and other pollinators—decline worldwide, researchers have established a variety of potential causes, including climate change, pesticides, and habitat loss. But now, new findings suggest yet another culprit may be part of the equation: night-time lighting, like street lights in populated areas. A team of entomologists in the United Kingdom looked at populations of moth caterpillars under street lights, compared to populations that lived in darkness all night. In conditions with night-time lighting, they found nearly half as many caterpillars, in some cases. In addition, caterpillars that grew up under street lights were bigger, suggesting that they might be stressed and attempting to rush into metamorphosis earlier than they should. Furthermore, the greatest threat seems to be coming from energy-efficient LED lights, whose bluer wavelengths may be more stressful than the warmer, redder light of older sodium bulbs. The team published their work in the journal Science Advanceslate last month. Guest host Umair Irfan talks to co-author Douglas Boyes about why nighttime lighting might be so bad for insects, and why ditching LED lights isn’t actually the best solution.     The Endemic End To The Pandemic Over the past year and a half, we’ve been talking about the COVID-19 pandemic. But there’s another stage of global virus spread to consider as well—the endemic stage. Instead of a sudden cacophony of viral noise, you can think of it as a constant low-level hum, with occasional bleeps.  Viruses such as the coronaviruses responsible for many colds, or the influenza virus, are already endemic worldwide. They’re pretty much everywhere, all the time—and sometimes make you ill. But they don’t usually threaten to overwhelm health systems the way COVID-19 is currently. Maureen Miller, an infectious disease epidemiologist and medical anthropologist at  Columbia University, joins guest host Umair Irfan to talk about pivoting from pandemic to endemic conditions, and what past outbreaks can teach us for future health decisions.       Charismatic Creature Carnival: Who Rules The Night? We’re in week two of our Charismatic Creature Carnival, our celebration of six overlooked or unfairly maligned species that deserve a closer look. Our audience submitted our candidates, but only one will be crowned the very first carnival inductee into the Charismatic Creature Corner Hall of Fame. This week’s friendly head-to-head battle is between the opossum and the aye-aye, submitted by listeners who remarked these creatures are cute, though unconventionally so. Defending the opossum is Lisa Walsh, postdoctoral researcher at the Donald Danforth Plant Science Center, based in Washington, D.C. Squaring up against them to support the aye-aye is Megan McGrath, education programs manager at the Duke Lemur Center in Durham, North Carolina. Find out how to participate in the final creature face-off and check out what you said about the last round between the mantis shrimp and the hellbender salamander!    Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Sep 17, 2021 • 47min

Living With Wildfire, 7,000 Steps A Day Okay, Kids’ Mars Questions. Sept 17, 2021, Part 1

Scientists Potty Train Cows To Lower Greenhouse Gasses Scientists have known it for a long time: Cattle are a major source of nitrogen emissions, contributing to the global warming crisis. Alternatives have been tossed around for years: from eating less meat to feeding cows seaweed. Now, a new study out of Germany and New Zealand has a more outside-the-box solution: potty-training calves. Scientists trained cows to pee in just one spot—dubbed the “MooLoo”—so their urine can be cleaned before it seeps into the environment. Most calves got the hang of it within 20-25 pees. Joining guest host Umair Irfan to talk about this and other science stories of the week is Roxanne Khamsi, science journalist based in Montreal, Quebec. With Worsening Wildfire Seasons, How Can We Learn To Live With Them? It’s another record year for fire in the American West, with more than two million acres already burning in the state of California, and the Dixie Fire alone well on its way to a million acres—if it gets that big, it would be the second “gigafire” on record, after 2020’s August Complex fire. As climate change and human habitation collide in worsening fire seasons, what is the long-term outlook? Guest host Umair Irfan talks to fire scientist Crystal Kolden about the way fires are changing as we change the landscape, and what coexisting with fire can look like—including learning from the time-proven burning and forestry practices of Indigenous peoples of the West. Do I Really Need 10,000 Steps A Day? Scientists Say 7,000 Is Fine You’ve probably heard someone say that they have to “get their steps in.” But does the number of steps you take in a day actually matter? For years, there was a mythology around the health benefits of walking 10,000 steps a day. But it turned out that number wasn’t based on actual data—it grew out of a marketing effort in Japan from a pedometer company in the 1960s. Now, Amanda Paluch, an assistant professor of kinesiology at the University of Massachusetts Amherst, has published a paper—based on actual data—to help answer this question in the academic journal JAMA Network Open. Mining data collected by the CARDIA cohort study, they compared the overall health outcomes of people who walked less than 7,000 steps a day, those logging 7,000 to 10,000 steps, and those trekking over 10,000. They found that people who walked over 7,000 steps a day had a significant decrease in mortality, compared to people who took fewer steps. They’re still trying to tease out exactly what health benefits the steps may bring. Paluch joins guest host Umair Irfan to talk about the research, and what you should know about how walking might improve health. NASA Scientist Answers Kids’ Questions About The Mars Rover It was big news last week when the Mars rover Perseverance collected its first rock samples. And just in time, we invited young listeners in our audience to ask research scientist Katie Stack Morgan of NASA’s Jet Propulsion Laboratory some of their most pressing questions about the Mars 2020 mission. Questions like, “How do samples get back to Earth from Mars?” And, “How does Perseverance dust itself off … if it can?     Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.
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Sep 10, 2021 • 47min

Covid And Disabilities, Alzheimer’s And Inflammation, Ultrasonic Sound. Sept 10, 2021, Part 1

New Policies Emerge In The Wake Of Climate-Connected Disasters This week, people across the United States continued to be reminded of the results of a shifting climate—with people in the Gulf states still recovering from Ida, northeastern states dealing with the aftermath of Hurricane Ida-induced flooding, and western states battling wildfires and smoke. With climate-related disasters as a backdrop, President Biden announced a goal of shifting some 45% of U.S. energy production to solar power by 2050. Kendra Pierre-Louis, senior reporter for the Gimlet-Spotify podcast How to Save A Planet, joins Ira to talk about those stories and more, including new calculations of the importance of minimizing fossil fuel extraction, to a successful sample collection effort on Martian soil.   Is Inflammation In The Brain Causing Alzheimer’s Disease? The brain of a person with Alzheimer’s disease has a few hallmark traits. First, a buildup of plaques made of proteins called amyloid beta. Second, are tangles of another protein, called tau, within individual neurons. A third major indicator is inflammation. While researchers have long thought brain inflammation was a byproduct of the disease itself, there’s a growing hypothesis that it might actually be a driver of the disease’s progression. That would help explain why researchers have found people whose brains are full of tau tangles and amyloid plaques, but with no outward symptoms of Alzheimer’s. Research on animals has supported this theory. But finding the same evidence in human brains is harder. Now, a team of scientists, writing in the journal Nature Medicine, thinks they have it: time-lapsed images of patient brains showing tau tangles and inflammation spreading through the brain in the exact same pattern. Ira talks to Dr. Tharick Pascoal, assistant professor at the University of Pittsburgh and the study’s first author, about this finding, and what it means for future research into Alzheimer’s therapies.   The World According To Sound: Ultrasonics The mating calls of the katydid, a large insect, are ultrasonic, beyond the audible limit of human hearing. What if we could hear them? That’s the focus behind a collaboration between the abstract audio podcast The World According To Sound and scientist Laurel Symes, the assistant director of the Center for Conservation Bioacoustics at Cornell University. In this recording, you’ll hear the sounds of one of her study animals—a group of katydids in a forest in Panama. Bill McQuay, sound engineer and an audio producer at the Cornell Lab of Ornithology, slowed down Symes’ recording so you can hear a whole world of ultrasonic activity open up, from ultrasonic mating calls of katydids to the ultrasonic pings of bats echolocating their next meal. The World According to Sound is a live audio show, online listening series, and miniature podcast that focuses on sound, not story. Producers Chris Hoff and Sam Harnett create intentional, communal listening experiences as a way to “reclaim autonomy in a visually dominated world that is increasingly fracturing our attention.” This katydid recording and more are a part of their next listening series, an immersive listening party where audiences from all over the globe will be invited to experience a world of sound together, beginning in January 2022.   How COVID-19 Reveals Existing Biases Against The Disability Community In early July, I visit Ingrid Tischer at the Berkeley apartment she’s shared with her husband, Ken, for the past 10 years. When I arrive, she’s already sitting outside at the top of a gently sloping ramp that leads up to the door. We’re both vaccinated, but we’re still taking precautions: masks, outdoors, and social distancing. That’s because Ingrid has a severe disability. “I have muscular dystrophy,” she tells me, “which is a neuromuscular disorder that I’ve had my entire life because it’s genetic.” Muscular dystrophy is a progressive muscle wasting disease. It impacts her mobility, including her ability to walk unassisted. Ingrid says she’s most impacted by having a weak respiratory system and uses an oxygen device called a biPap to help her breathe. Earlier in the pandemic, her doctor told her that if she got COVID, it would likely be a death sentence. “I’d never heard my situation put in such stark, certain terms,” she says. Ingrid is in her mid 50s, with graying brown hair and bright blue eyes. She leads fundraising for DREDF, a disability rights and legal advocacy organization. She’s also a writer — she’s written a draft of a novel and has a blog called “Tales From the Crip.” In addition to a brilliant title, the blog is full of her personal reflections about navigating a world in which the needs and feelings of people with disabilities go mostly unseen and ignored. When COVID hit in the spring of 2020, Ingrid was terrified. Because of the risk of infection and smoke from the wildfires that summer, she stopped leaving her house entirely, developed severe anxiety and depression, and began noticing a host of new health issues. Her feet and legs began swelling and breathing became even more difficult than usual. Her doctor worried she might be developing congestive heart failure, but told her to stay home rather than come in for tests and risk infection. It’s a common story. A recent survey by the disability advocacy group #NoBodyIsDisposable found that many disabled people have delayed medical care for over a year due to concerns about COVID-19. Read more at sciencefriday.com.   Subscribe to this podcast. Plus, to stay updated on all things science, sign up for Science Friday's newsletters.

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