Big Technology Podcast

Don Graham, the former owner of The Washington Post, shares fascinating insights from his experiences with tech titans Mark Zuckerberg and Jeff Bezos. He recounts a memorable early meeting with Zuckerberg and how he proposed an investment that was turned down. Graham’s reflections on selling The Washington Post to Bezos reveal the latter's profound love for reading and its influence on innovations like the Kindle. They also dive into what defines true success beyond just wealth, exploring the societal contributions of various professions.

Trevor Martin, the CEO and co-founder of Mammoth Biosciences, shares insights on CRISPR technology, revolutionizing gene editing today rather than in a distant future. He discusses its potential to treat genetic diseases and the ethical implications of editing genes, especially concerning enhancing human capabilities. The conversation also dives into the accessibility challenges of biotechnology and the importance of societal consensus on genetic advancements, highlighting how these developments could reshape health outcomes and ethical boundaries in society.

Kara Swisher, co-founder of Recode and New York Times columnist, joins the discussion with her sharp insights on tech. She delves into the dual nature of cryptocurrency—how it’s both a tool for crime and a legitimate asset, while also navigating the chaotic leadership transitions at major firms like Meta. Swisher shares her views on the evolving media landscape and the importance of adaptability. With a focus on optimism, she highlights innovations in tech that could reshape our future, from self-driving cars to advancements in healthcare.

Join Josh Brown, CEO of Ritholtz Wealth Management and CNBC contributor, as he delves into the shocking $251 billion drop in Meta's stock. He discusses market phenomena like 'whisper' earnings and why growth stocks may be losing their appeal. The conversation turns to Meta's rebranding challenges and competition with TikTok and Alphabet. Brown also highlights shifts toward short-term profits amid rising interest rates, alongside the volatility in biotech and cryptocurrency markets that investors must navigate.

Brian Morrissey, writer of The Rebooting newsletter and former editor-in-chief of Digiday, dives into the evolution of digital publishing. He discusses the shift from social media dependence to prioritizing quality content and dedicated audiences. Exploring the rise of niche publications, he highlights innovative revenue strategies and the importance of genuine engagement. Morrissey also touches on the implications of Web3 and cryptocurrency, shedding light on the changing landscape of entrepreneurship and the future of journalism.

Dr. Tom Insel, the former director of the National Institute of Mental Health and current leader in mental health innovation at Alphabet's Verily, discusses the intersection of technology and mental health. He highlights how smartphone data can transform treatment methodologies while addressing privacy concerns. Insel explores the dual nature of social media, weighing its benefits against potential harms, particularly for youth during the COVID era. He also emphasizes the urgency for innovative solutions targeting serious mental illnesses, fostering hope for the future of mental health care.

Clare Malone, a staff writer at The New Yorker, delves into the world of conservative social networks, particularly Gettr, while David Thiel, CTO at Stanford Internet Observatory, shares insights from his research. They discuss Gettr's growth as a rival to Twitter and its strategies for international expansion. The pair explores user engagement challenges, the influence of figures like Guo Wengui, and the complexities of content moderation. They also examine how platforms influence political discourse ahead of the 2024 election.

Senator Mark Warner, a seasoned U.S. Senator from Virginia, shares his insights on the urgent need to regulate Big Tech after a decade in office. He dives into the covert tactics these companies employ against regulation and the challenges Congress faces in passing meaningful legislation. The conversation touches on congressional stock trading ethics and the pressing need for privacy laws. Warner emphasizes the importance of balancing innovation with accountability to foster fair competition and protect consumer interests amid rising political stakes.

Aaron Levie, CEO of Box, dives into the complex world of Web3, shedding light on both its potential and pitfalls. He discusses how decentralization could transform the internet but warns about the hurdles in making it user-friendly. Levie questions whether current approaches truly empower users or just replicate existing structures. Additionally, he addresses the need for sustainable monetization for creators and the philosophical debates surrounding digital ownership, providing a nuanced perspective on the future of our digital landscape.

Casey Newton, Editor of Platformer and CNBC contributor, dives into the tech landscape of 2021, discussing significant leadership shifts at major companies like Facebook and Twitter. He examines the emergence of Web3 and whether the cult of the founder is fading. The conversation covers the challenges tech faces under authoritarian regimes and the heated debates surrounding cryptocurrency and NFTs. With a blend of skepticism and optimism, Casey shares predictions for 2022, reflecting on a year of tech transition and consumer trends.