Big Biology

What can we learn from the COVID-19 pandemic, and how do we apply that knowledge moving forward?On this special episode of Big Biology, we’re bringing you the highlights from a conference called “Covid Conversations,” which was hosted at the University of South Florida last December. The event brought together scientists, public health experts, medical doctors, historians, students, philosophers, and community leaders—for one big, open conversation about COVID-19. The episode shares the different perspectives these speakers had on the virus, the pandemic response, and our future preparedness to disease.This episode is hosted by Caroline Merriman, a Big Biology intern and a research fellow with the Association of Public Health Laboratories program, and Kailey McCain, a PhD student in Marty’s lab at USF and a former Big Biology intern.Cover art by Keating Shahmehri This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit bigbiology.substack.com/subscribe

How can grad students advocate for science policy? How can science communication make research more accessible and inclusive?On this episode of Big Biology, we bring back our “Student Spotlight” segment. We talk with JP Flores, a PhD student studying bioinformatics and computational biology at UNC Chapel Hill. JP does more than just research, he is also deeply engaged in science communication and hosts the award-winning podcast From where does it STEM? He has also worked in science policy as an intern at the NIH and is part of the Science Policy and Advocacy Group at UNC. Earlier this year, JP helped to organize the Stand Up for Science 2025 protest and as a result of the movement, co-founded the non-profit Science for Good. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit bigbiology.substack.com/subscribe

This is a free preview of a paid episode. To hear more, visit bigbiology.substack.comWhat role does media play in conservation efforts and inspiring future generations of scientists? How can science communication make scientific knowledge accessible to the public, especially for communities underrepresented in science?On this episode, we talk with Dr Rae Wynn-Grant a researcher at the Bren School of Environmental Science and Management …

This is a free preview of a paid episode. To hear more, visit bigbiology.substack.comWhat biological "superpowers" do marine invertebrates possess? What challenges do they face and will their resilience protect them from anthropogenic change?On this episode, we talk with Drew Harvell, Professor Emerita of Ecology and Evolutionary Biology at Cornell University, Affiliate Faculty at the University of Washington, former Science Envoy for O…

Why is the National Science Foundation important? What is the potential impact of the proposed budget cut to the NSF? How can we stand up for federally-funded science in the US?In this episode, we talk with Bill Zamer and Sam Scheiner, two former BIO program officers at the NSF. Much of the conversation focuses on the recently proposed 56% budget cut to the NSF and what the impacts of such a spending cut would be on science in the US. We discuss how the NSF came to be, the proposal selection process, and some of the scientific breakthroughs that have come out of the NSF-supported basic research. The episode also has suggestions of how to show your support for the NSF including calling your representatives, talking about the importance of the NSF and sharing this episode widely, and taking action suggested by the coalition SaveNSF. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit bigbiology.substack.com/subscribe

Watch how our amazing artist Keating Shahmehri created the cover art for our last episode "Feel the heat”. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit bigbiology.substack.com/subscribe

How do scientists measure thermal tolerance and predict organismal responses in the wild? What kind of other data is needed to make predictive models better at helping us understand species responses to high temperatures?In this special episode, roving podcaster Cameron Ghalambor went on the road to the University of Granada in Spain where he spoke about his own research in the symposium, Predictive Ecology in a Warming World. While there, Cam was inspired to get a few of the other experts into a room to talk about the broader field of predictive ecology, and this episode is the result. Guests on the episode include Jancitha Ellers, Professor at Vrije University of Amsterdam, Enrico Rezende, Associate Professor at Pontifical Catholic University of Chile, and Wilco Verberk, Associate Professor at Radboud University. Cam and colleagues discuss the methods and tools they use to measure heat tolerance in insects, fish, and other ectothermic animals and how collecting and sharing trait data is important to inform and implement predictive models.Cover art by Keating Shahmehri This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit bigbiology.substack.com/subscribe

Scott Edwards, the Alexander Agassiz Professor of Zoology and Curator of Ornithology at Harvard, dives into the evolution of genomic research. He explores how new DNA sequencing technologies help reveal complex genomic structures, likening them to navigating a well-organized bookstore. The conversation shifts to cooperative breeding among babblers in varied habitats, highlighting the role of genomic advancements in understanding ecological traits. Edwards emphasizes the intricate connections between natural history and genomics, shaping our understanding of biodiversity.

In this post-match chat, Marty and Cam discuss our most recent episode “A direct hit”, with guest Holden Thorp. This is a quickly evolving situation, and on Friday last week, a federal judge continued to block the cut to the NIH indirect cost rate. And just a few days ago, Holden wrote another editorial Come together, right now. He writes about the continued onslaught of cuts, firings, and changes to the science system in the United States, and how members of the scientific community can respond. This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit bigbiology.substack.com/subscribe

Will a change in policy at the National Institutes of Health derail science in the US? How does the “indirect cost rate” for federal research grants fuel research?In this episode, we talk with Holden Thorp, a chemist and editor-in-chief of Science, about his recent editorial A Direct Hit. In it, he writes about the NIH announcing a significant cut to their indirect cost rate and the consequences to science in the US if this change takes effect. “Indirect” or “overhead” costs are the portions of grants that are allocated to support research grant but aren’t for the research itself. Things like grant administration, compliance, and research infrastructure are covered by these funds (check out the comic below by Matteo Farinella for details). These costs have traditionally been shared by universities and the federal government, but with the proposed cut to the indirect cost rate, universities may need to make up for the deficit or change their operations. We discuss with Holden how this change could have widespread impacts on scientific research as well as the economy including our competitiveness on the global stage.Comic by Matteo Farinella (Instagram, Substack) This is a public episode. If you'd like to discuss this with other subscribers or get access to bonus episodes, visit bigbiology.substack.com/subscribe