
The Defiant - DeFi Podcast
The internet of money is being built with blockchain technology and without banks. We call it DeFi, short for Decentralized Finance, and this is where you can hear the builders and users of this cutting edge world tell their stories first hand. Hosted by Camila Russo.
Latest episodes

Jun 23, 2025 • 1h 7min
Emin Gün Sirer on Scaling Avalanche and Redefining Decentralization
Emin Gün Sirer, CEO and Founder of Ava Labs, is a pioneer in blockchain technology, particularly known for his work on the Avalanche protocol. In this discussion, he reveals how Avalanche's innovative consensus mechanism sets it apart from Bitcoin and Ethereum. Emin explores the challenges of centralization, the advantages of multi-chain scaling, and how Avalanche fosters interoperability. He also dives into the future of stablecoins in relation to central banks and highlights the rising interest and activity within the Avalanche ecosystem.

Jun 20, 2025 • 41min
Ethereum Staking ETFs: How They Could Transform Crypto Investing | Insights with Evan Weiss
Evan Weiss, COO of Alluvial and founder of the Proof of Stake Alliance, shares valuable insights into the rising trend of Ethereum Staking ETFs. He discusses the regulatory landscape and its evolving dynamics on Capitol Hill. The conversation highlights how these ETFs could democratize crypto investments, improve staking yields, and enhance security for individuals. Weiss also examines the role of institutions in shaping staking infrastructure and the significance of liquidity for everyday users in this transformative financial landscape.

Jun 13, 2025 • 56min
Every Company Will Be a Crypto Company: Expert Insights with Sandy Kaul from Franklin Templeton
Sandy Kaul, Head of Innovation at Franklin Templeton, discusses how traditional finance is evolving with crypto. She highlights groundbreaking projects like onchain money market funds and explores the transformative potential of DeFi in supply chain and asset management. Kaul also addresses the obstacles posed by regulation and the exciting future of integrated financial services, emphasizing that every company could soon embrace crypto as a standard. Tune in for insights into the innovative landscape reshaping global finance.

Jun 11, 2025 • 51min
NFC Lisbon Recap: Art, Finance, and Digital Economies with Alex Estorick
Alex Estorick, Editor in Chief of Right Click Save, dives into the transformative world of NFTs and digital art. He discusses the convergence of art and finance, exploring how NFTs challenge traditional art categorization. The rise of meme coins as cultural artifacts connects financial phenomena to artistic expression. Estorick also highlights the diverse perspectives within the crypto community and the evolving challenges artists face with royalties. Lastly, he envisions a future where artists leverage DeFi tools and regain control over their digital creations.

51 snips
Jun 6, 2025 • 57min
Ethereum's Next Moves: Insights from Tomasz Stańczak and the Ethereum Foundation
In this engaging discussion, Tomasz Stańczak, Co-Executive Director of the Ethereum Foundation and early team member of Flashbots, shares transformative insights on Ethereum's evolution. He highlights the foundation's efforts to improve communication and transparency while addressing community feedback. Tomasz dives into strategic initiatives for ecosystem growth, emphasizing the significance of Layer 1 and Layer 2 relationships. He envisions Ethereum as a hub for a global economy, balancing user needs and core values, and outlines innovative treasury strategies to enhance support for developers.

Jun 4, 2025 • 49min
Zero Knowledge Proofs: The Game-Changer for Digital Privacy You Need to Know, Featuring Rob Viglione
This week, we spoke with Rob Viglione, Co-founder and CEO of Horizen Labs, to explore the groundbreaking potential of Zero Knowledge Proofs (ZKP) in safeguarding digital privacy, bridging TradFi and DeFi, and creating income streams for consumers that empower them through the ownership of their own digital data. From balancing transparency and onchain privacy to the intersection of AI and Web3, Rob dives into the critical role cryptography will play in reshaping how we share and protect data. Learn how ZKPs can combat data misuse, empower individuals to monetize their information, and reimagine compliance as we step into a world where privacy is a fundamental human right. Key Highlights:1. How ZKPs protect medical records and financial history2. Will banks adapt, or become irrelevant?3. The role of cryptography in privacy-centric AI systemsDon’t miss this thought-provoking discussion packed with insights on the future of data, privacy, and decentralized innovation. Chapters:00:00 Defiant Intro00:07 Podcast Teaser00:52 Hero Quote00:59 Introduction to Rob Viglione01:34 The beauty of ZKPs02:40 How to balance transparency and privacy onchain04:00 Why it’s so easy to overshare data04:50 Living in an age of constant data leaks06:34 The concept of wealth is fundamentally different now07:33 Google adopts ZKP to verify age09:00 A world of a trillion proofs09:30 How can Web3 handle growing volumes of proofs?10:09 Will Web2 relinquish their chokehold on our data?11:52 Monetizing data as an incentive to online privacy12:45 New opportunities for earning a living by monetizing your data14:14 The intersection of crypto and AI16:17 ZKPs and data protection18:00 ZKPs and AI in medical records and financial history20:18 How can ZKPs act as a safeguard against misuse in AI22:15 Hackers and scammers are a certainty; how do we fight them?22:36 Cryptography, ZKPs, and privacy-centric AI systems?25:13 Why is privacy a human right?26:25 Institutions, privacy, and Web326:45 Institutions coming onchain28:30 Better communicating privacy as a human right in the context of Web330:30 Will ZKPs change the way people interact with the internet?32:11 Marketing in the age of AI33:24 ZKPs and KYC35:40 Why ZKPs are bad for bad actors37:38 Government regulation vs. Web3 companies regulating the industry themselves39:00 It doesn’t make sense for politicians to be anti-crypto anymore41:53 Can ZKPs redefine compliance and how it’s enforced?43:13 How can ZKP tech support institutional privacy and consumer data?44:45 TradFi onchain as a stepping stone to DeFi46:39 Lightning round! Favorite existing use case for ZKP46:54 Lightning round! Favorite potential use case for ZKP48:04 Lightning round! Best advice for keeping your data safe online48:49 Closing statements and where to follow Rob

May 31, 2025 • 41min
How Payroll, Stablecoins & Regulation Are Reshaping Global Economies | Megan Knab
In this discussion, Megan Knab, cofounder and CEO of Franklin, dives into the transformative power of crypto payroll and stablecoins. With a background in finance, she skillfully tackles issues like crypto volatility and compliance with labor laws. The conversation spans the significant role of stablecoins in reshaping economies and how they can streamline payroll processes. Megan also sheds light on the balance between innovation and regulation, emphasizing the need for transparency and the potential of decentralized finance to enhance financial accessibility.

13 snips
May 16, 2025 • 59min
AI Agents, Meme Coins, and a Better Future for Investing: Insights from Shaw Walters
Shaw Walters, Founder of Eliza Labs and creator of an innovative OS for AI agents, shares his insights on the convergence of AI and cryptocurrency. He discusses how AI can enhance collaboration in organizations and transform the investment landscape through decentralized finance. Walters advocates for 'fairer-than-fair' token launches and emphasizes the need for genuine utility over hype. He also explores the challenges of market manipulation and the crucial role of community-driven innovation in shaping a better future for investing.

4 snips
May 15, 2025 • 1h 14min
The Fight for Digital Privacy Decentralized AI and the Future of Freedom with Patrick Amadon
Patrick Amadon, an artist and digital activist, delves into the critical themes of digital privacy, censorship, and decentralized AI. He discusses how decentralized platforms, like Ethereum, can empower individuals and artists, while exploring the dangers of centralized AI. Amadon emphasizes the importance of digital disobedience in countering authoritarianism and protecting free speech. He highlights the need for innovative solutions to safeguard privacy and argues for a renewed focus on data ownership in the evolving tech landscape.

May 9, 2025 • 1h 7min
Beyond the Hype: Bitcoin, Inflation, and the Future of Crypto with Gus Grillasca
In this engaging discussion, Gus Grillasca, a cypherpunk and artist known for his work with Bitcoin Ordinals and NFTs, dives into the complex interplay between cryptocurrency and global economics. He critiques inflation as banker propaganda and shares his own journey navigating the challenges of finance in Europe as a Mexican artist. Topics include the future of Bitcoin as a treasury asset, the potential of crypto in Latin America, and the risks of meme coins compared to stable investments. Gus also emphasizes the importance of financial literacy in fostering blockchain adoption.