The Defiant - DeFi Podcast

Camila Russo
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Nov 14, 2025 • 37min

​​Is DYOR Dead? Building a Safer Web3 with Alex Katz

In this discussion, Alex Katz, CEO of Kerberus, a Web3 security company, tackles the notion that 'Do Your Own Research' is no longer enough in a rapidly evolving crypto landscape filled with sophisticated scams. He highlights the risks of mobile crypto, such as address poisoning and malware, while advocating for automated security solutions that protect users by default. Katz also shares insights on Kerberus' track record of zero-user losses and envisions a future where robust safeguards allow everyone, including the elderly, to navigate Web3 safely.
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Nov 12, 2025 • 15min

Avalanche DeFi: the Journey to Bring Institutions Onchain

Explore the dynamic journey of Avalanche as it navigates through market fluctuations, focusing on rebuilding DeFi protocols. Hear about groundbreaking upgrades like Octane and Etna aimed at reducing fees, and the advancements in Interchain Messaging for enhanced blockchain interoperability. Discover how Avalanche is targeting institutional clients by providing tailored Layer 1 solutions and strategizing to draw in traditional finance flows. The emergence of a robust on-chain financial system combines lending, staking, and trading, setting the stage for mainstream adoption.
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Nov 7, 2025 • 42min

Inside the PYUSD's takeover of PayPal with May Zabaneh, VP Crypto

May Zabaneh, VP of Product for Crypto at PayPal, dives into the exciting world of PYUSD, PayPal's new stablecoin. She explains how it aims to lower cross-border payment costs and enhance financial inclusion. Their proprietary stablecoin supports faster transactions within PayPal and Venmo, positioning itself for international expansion. The conversation also touches on merchant adoption, the blend of DeFi with traditional finance, and the vital role of interoperability in digital payments. Zabaneh even hints at how AI can revolutionize commerce with stablecoins!
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Oct 21, 2025 • 1h 1min

Why Yat Siu Believes Altcoins Will Surpass Bitcoin

Yat Siu, co-founder of Animoca Brands and a visionary in Web3 and gaming, shares insights on digital identity and the future of altcoins. He unveils plans for a Hong Kong dollar stablecoin, emphasizing its potential to combat digital fraud. Siu discusses the creation of the Mocaverse, a system allowing verifiable identities across chains, and argues that altcoins might collectively eclipse Bitcoin due to their innovation and utility. He also predicts that upcoming games, like GTA 6, will drive mainstream adoption of crypto in gaming.
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26 snips
Oct 17, 2025 • 47min

The AI CEO Era: Breaking Build Bottlenecks with Vibe Coding | Ahmad Shadid

Ahmad Shadid, a former quant trader turned founder of O.xyz, explores groundbreaking concepts in AI and decentralized networks. He shares the transformative potential of vibe coding, which enables rapid product development at 20x speed. The discussion delves into the ideas of sovereign superintelligence and AI-managed organizations, questioning the balance between automation and human leadership. Ahmad also highlights emerging security challenges in this fast-paced development landscape, predicting an explosion of startups as barriers diminish.
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Oct 14, 2025 • 27min

How Avalanche is Tackling the Blockchain Trilemma

Luigi D’Onorio DeMeo, a product leader at Ava Labs, explores Avalanche's innovative blockchain technology. He discusses how randomized consensus enables sub-second finality and balances decentralization with speed. Luigi unveils the 'city of chains' model, emphasizing customizable Layer 1 solutions and inter-chain messaging for liquidity sharing. He also highlights the appeal for enterprises and the importance of measuring decentralization through validator counts. The conversation touches on real-world applications, financial inclusion, and the future of programmable finance.
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Oct 10, 2025 • 47min

What Crypto VCs Want Now | Aryan Sheikhalian

Aryan Sheikhalian, Head of Research at CMT Digital, dives into the future of crypto as an infrastructure rather than just an asset. He shares insights on tokenized equities and how they can transform traditional finance with 24/7 markets. Aryan discusses the importance of identity layers and ZK proofs for mainstream adoption, and how regulation is steering firms toward partnerships. He also highlights the potential of overlooked sectors like decentralized data, and offers sage advice for founders to focus on user needs and maintain conviction.
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5 snips
Oct 6, 2025 • 36min

Solana vs. Bitcoin: Why Pantera Capital is All In | Paul Veradittakit

Paul Veradittakit, Managing Partner at Pantera Capital, shares his extensive experience in crypto investment and discusses Solana’s rapid growth. He explains why Pantera has heavily invested in Solana, detailing its technological advantages and potential in gaming and payments. The conversation also covers the current landscape of stablecoins, the evolution of digital asset treasuries, and why altcoins may outperform Bitcoin this cycle. Veradittakit emphasizes Solana's future and addresses concerns about its decentralization and downtime.
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6 snips
Oct 3, 2025 • 46min

Can Crypto Be Trusted? Ben Nadareski’s Answer to the Skeptics

Ben Nadareski, CEO and co-founder of Solstice Labs, shares insights on DeFi’s evolution on Solana, a blockchain shaking off its 'meme chain' label. He discusses Solana's advantages like speed and low costs, driving institutional adoption. Ben covers the rise of yield-bearing stablecoins and how Solstice's innovations unlock trust and scalability. He addresses network stability and regulation, emphasizing targeted standards for user protection. The conversation highlights DeFi’s potential to empower users in emerging markets and the future of yield strategies.
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11 snips
Oct 1, 2025 • 54min

StarkWare Bets on Becoming Bitcoin's Execution Layer, Not on Attracting Corporate Chains

Eli Ben-Sasson, co-founder and CEO of StarkWare, shares his expertise in zero-knowledge proofs and blockchain scalability. He discusses how StarkNet is innovating Bitcoin staking with a $100M incentive program. Eli elaborates on StarkNet’s role as Bitcoin's execution layer and its potential for creating an 'integrity web' that connects identity and value flow. He also highlights the groundbreaking ability to verify Bitcoin headers in milliseconds and the importance of decentralization in transforming finance.

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