In this episode Dr Katz talks a specific study comparing a Mediterranean to a keto diet and also discusses diet study design and why so many are pre-decided. We also talk about calorie restriction and intermittent fasting. Dr Katz was an early proponent of preventative medicine and is the founder and former president of the Yale-Griffin Prevention Research Center. As well as appearing on ABC News and Good Morning America he has written 13 books including The Truth About Food and How to eat. He is the founder and CEO of Diet ID a company that makes a tool to help measure and manage diet. And with that let me start the interview. Dr Katz's home page https://davidkatzmd.com/ Diet ID https://www.dietid.com/ Dr Catherine Katz food site https://cuisinicity.com/ Find Dr Katz's books on Amazon How To Eat: All Your Food and Diet Questions Answered https://amzn.to/3TiNbkd The Truth About Food https://amzn.to/3ARckLz The Way to Eat: A Six-Step Path to Lifelong Weight Control https://amzn.to/3QT2m27 Disease-Proof: Slash Your Risk of Heart Disease, Cancer, Diabetes, and More--by 80 Percent https://amzn.to/3pQV96w Papers referred to in this series Actual Causes of Death in the United States https://jamanetwork.com/journals/jama/article-abstract/409171 Actual Causes of Death in the United States, 2000 https://jamanetwork.com/journals/jama/article-abstract/198357 The Global Burden of Disease - Lancet web page https://www.thelancet.com/gbd

In this episode Dr Katz talks about his path to preventative medicine and how important it is. We then get into the number one modifiable cause of chronic diseases which is diet. Dr Katz was an early proponent of preventative medicine and is the founder and former president of the Yale-Griffin Prevention Research Center. As well as appearing on ABC News and Good Morning America he has written 13 books including The Truth About Food and How to eat. He is the founder and CEO of Diet ID a company that makes a tool to help measure and manage diet. And with that let me start the interview. Dr Katz's home page https://davidkatzmd.com/ Diet ID https://www.dietid.com/ Dr Catherine Katz food site https://cuisinicity.com/ Find Dr Katz's books on Amazon How To Eat: All Your Food and Diet Questions Answered https://amzn.to/3TiNbkd The Truth About Food https://amzn.to/3ARckLz The Way to Eat: A Six-Step Path to Lifelong Weight Control https://amzn.to/3QT2m27 Disease-Proof: Slash Your Risk of Heart Disease, Cancer, Diabetes, and More--by 80 Percent https://amzn.to/3pQV96w Papers referred to in this series Actual Causes of Death in the United States https://jamanetwork.com/journals/jama/article-abstract/409171 Actual Causes of Death in the United States, 2000 https://jamanetwork.com/journals/jama/article-abstract/198357 The Global Burden of Disease - Lancet web page https://www.thelancet.com/gbd

In this episode Professor Furman shares his personal protocol to stay healthy and have low inflammation and talks about where the longevity industry is going and where he thinks it should put its focus. Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. Furman received his Ph.D. (summa cum laude) from University of Buenos Aires, Argentina, for his work on the identification of factors produced by tumors that enable cancer cells to escape immune attack. During his postdoctoral training at the Stanford School of Medicine, Dr. Furman focused on the application of advanced analytics to study the aging of the immune system in humans and decipher how cumulative inflammatory responses associated with aging lead to an accelerated cardiovascular aging. Dr. Furman has published dozens of scientific articles in top-tier journals such as Cell, Nature Medicine, PNAS, The Lancet, and others. Dr Furman's paper on iAGE An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging https://www.nature.com/articles/s43587-021-00082-y https://www.biorxiv.org/content/10.1101/840363v1 Prof David Furman’s Lab in Buck Institute Website https://www.buckinstitute.org/lab/furman-lab/ Stanford 1000 Immunomes Project (KIP) Website: https://med.stanford.edu/1000immunomes If you would like to support our channel, we’d love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan 15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15. Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/ 10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/ $5 off any purchase if users use code MODERN5 at NOVOS Labs https://novoslabs.com/?ref=3957

Edifice Health aim not to only measure inflammatory age but to also to provide supplements and suggest actions to improve it. In this episode we talk about how these will be determined and some of the future direction. We also talk about the anti-inflammatory nature of caffeine. Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. Furman received his Ph.D. (summa cum laude) from University of Buenos Aires, Argentina, for his work on the identification of factors produced by tumors that enable cancer cells to escape immune attack. During his postdoctoral training at the Stanford School of Medicine, Dr. Furman focused on the application of advanced analytics to study the aging of the immune system in humans and decipher how cumulative inflammatory responses associated with aging lead to an accelerated cardiovascular aging. Dr. Furman has published dozens of scientific articles in top-tier journals such as Cell, Nature Medicine, PNAS, The Lancet, and others. Dr Furman's paper on iAGE An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging https://www.nature.com/articles/s43587-021-00082-y https://www.biorxiv.org/content/10.1101/840363v1 Prof David Furman’s Lab in Buck Institute Website https://www.buckinstitute.org/lab/furman-lab/ Stanford 1000 Immunomes Project (KIP) Website: https://med.stanford.edu/1000immunomes If you would like to support our channel, we’d love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan 15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15. Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/ 10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/ $5 off any purchase if users use code MODERN5 at NOVOS Labs https://novoslabs.com/?ref=3957

In this episode Dr Furman discusses the Stanford 1000 immunome project, the company that he set up to commercialize the iAge test, Edifice Health and the test itself. Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. Furman received his Ph.D. (summa cum laude) from University of Buenos Aires, Argentina, for his work on the identification of factors produced by tumors that enable cancer cells to escape immune attack. During his postdoctoral training at the Stanford School of Medicine, Dr. Furman focused on the application of advanced analytics to study the aging of the immune system in humans and decipher how cumulative inflammatory responses associated with aging lead to an accelerated cardiovascular aging. Dr. Furman has published dozens of scientific articles in top-tier journals such as Cell, Nature Medicine, PNAS, The Lancet, and others. Dr Furman's paper on iAGE An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging https://www.nature.com/articles/s43587-021-00082-y https://www.biorxiv.org/content/10.1101/840363v1 Prof David Furman’s Lab in Buck Institute Website https://www.buckinstitute.org/lab/furman-lab/ Stanford 1000 Immunomes Project (KIP) Website: https://med.stanford.edu/1000immunomes If you would like to support our channel, we’d love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan 15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15. Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/ 10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/ $5 off any purchase if users use code MODERN5 at NOVOS Labs https://novoslabs.com/?ref=3957

In this episode Dr Furman discusses what are the chief components of that make up the iAge clock and how they differ from the markers of acute inflammation. In particular CXCL9 is the main element of the iAge clock while classic marker of inflammation such as CRP, IL-6, TNF-alpha do not appear at all. Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. Furman received his Ph.D. (summa cum laude) from University of Buenos Aires, Argentina, for his work on the identification of factors produced by tumors that enable cancer cells to escape immune attack. During his postdoctoral training at the Stanford School of Medicine, Dr. Furman focused on the application of advanced analytics to study the aging of the immune system in humans and decipher how cumulative inflammatory responses associated with aging lead to an accelerated cardiovascular aging. Dr. Furman has published dozens of scientific articles in top-tier journals such as Cell, Nature Medicine, PNAS, The Lancet, and others. Dr Furman's paper on iAGE An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging https://www.nature.com/articles/s43587-021-00082-y https://www.biorxiv.org/content/10.1101/840363v1 Prof David Furman’s Lab in Buck Institute Website https://www.buckinstitute.org/lab/furman-lab/ Stanford 1000 Immunomes Project (KIP) Website: https://med.stanford.edu/1000immunomes If you would like to support our channel, we’d love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan 15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15. Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/ 10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/ $5 off any purchase if users use code MODERN5 at NOVOS Labs https://novoslabs.com/?ref=3957

Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. Furman received his Ph.D. (summa cum laude) from University of Buenos Aires, Argentina, for his work on the identification of factors produced by tumors that enable cancer cells to escape immune attack. During his postdoctoral training at the Stanford School of Medicine, Dr. Furman focused on the application of advanced analytics to study the aging of the immune system in humans and decipher how cumulative inflammatory responses associated with aging lead to an accelerated cardiovascular aging. Dr. Furman has published dozens of scientific articles in top-tier journals such as Cell, Nature Medicine, PNAS, The Lancet, and others. Dr Furman's paper on iAGE An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging https://www.nature.com/articles/s43587-021-00082-y https://www.biorxiv.org/content/10.1101/840363v1 Prof David Furman’s Lab in Buck Institute Website https://www.buckinstitute.org/lab/furman-lab/ Stanford 1000 Immunomes Project (KIP) Website: https://med.stanford.edu/1000immunomes If you would like to support our channel, we’d love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan 15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15. Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/ 10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/ $5 off any purchase if users use code MODERN5 at NOVOS Labs https://novoslabs.com/?ref=3957

In this episode Dr Furman discusses chronic inflammation and how it differs from acute inflammation. Dr. David Furman is the Director of the Stanford 1000 Immunomes Project, Chief of the Center for AI and Data Science of Aging at the Buck Institute for Research on Aging, and a Adjunct Investigator for The National Scientific and Research Council, Austral University, Buenos Aires, Argentina. Dr. Furman received his Ph.D. (summa cum laude) from University of Buenos Aires, Argentina, for his work on the identification of factors produced by tumors that enable cancer cells to escape immune attack. During his postdoctoral training at the Stanford School of Medicine, Dr. Furman focused on the application of advanced analytics to study the aging of the immune system in humans and decipher how cumulative inflammatory responses associated with aging lead to an accelerated cardiovascular aging. Dr. Furman has published dozens of scientific articles in top-tier journals such as Cell, Nature Medicine, PNAS, The Lancet, and others. Dr Furman's paper on iAGE An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging https://www.nature.com/articles/s43587-021-00082-y https://www.biorxiv.org/content/10.1101/840363v1 Prof David Furman’s Lab in Buck Institute Website https://www.buckinstitute.org/lab/furman-lab/ Stanford 1000 Immunomes Project (KIP) Website: https://med.stanford.edu/1000immunomes If you would like to support our channel, we’d love a coffee ☕…thank you! https://www.buymeacoffee.com/mhealthspan You can also find us on YouTube at https://www.youtube.com/c/modernhealthspan 15% off Bulletproof products at https://www.bulletproof.com/ with discount code HEALTHSPAN15. Renue By Science 10% discount code MHS at https://renuebyscience.com/all-products-2/ 10% off all products at DoNotAge with code MODERNHEALTHSPAN at https://donotage.org/ $5 off any purchase if users use code MODERN5 at NOVOS Labs https://novoslabs.com/?ref=3957

In this episode Dr Kaufmann talks about her personal protocol, how many supplements she takes (52) and some of the more advanced therapies that she uses, such as exosomes. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder of the Kaufmann Antiaging Institute and the author of the book The Kaufmann Protocol: Why We Age and How to Stop It. In the book she describes the mechanisms of aging on a cellular level and the best supplements to slow down its progress. Links for Dr Kaufmann The Kaufmann Protocol website https://kaufmannprotocol.com/ The Kaufmann Protocol: https://amzn.to/3rhBAq7

In this episode Dr Kaufmann talks about supplements and eye drops for aging eyes, including carnosine eye drops which may be able to reverse long sight. Sandra Kaufmann, is a cell biologist who for the last seven years has been the Chief of Pediatric Anesthesia at the Joe DiMaggio Children’s Hospital. She is also the founder of the Kaufmann Antiaging Institute and the author of the book The Kaufmann Protocol: Why We Age and How to Stop It. In the book she describes the mechanisms of aging on a cellular level and the best supplements to slow down its progress. Links for Dr Kaufmann The Kaufmann Protocol website https://kaufmannprotocol.com/ The Kaufmann Protocol: https://amzn.to/3rhBAq7