The Effective Statistician - in association with PSI

Alexander Schacht and Benjamin Piske, biometricians, statisticians and leaders in the pharma industry
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Jan 6, 2020 • 40min

Overview of different indirect comparison approaches and methods

Click this link to go to the homepage of the post. We specifically address the following points: Reasons for IC The classical Bucher approach vs matching adjusted indirect comparisons (MAIC)How to incorporated meta-analysesDifferent network-meta-analyses approaches (NMA): Bayes vs Frequentistsystematic literature reviews (SLR)Cochrane handbookTools VisualizationsBias Precision vs biasPre-specified vs post-hocSecondary vs primary endpointsPower of ICPublish detailed analysesFurther references:PRISMA http://prisma-statement.org/PRISMAStatement/Earlier podcast episode:Network meta-analyses: why, what, and how Listen to this episode and know more about Indirect Comparison now!
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Dec 23, 2019 • 47min

Christmas episode 2019

Click this link to go to the homepage of this post! During this episode, we will review some of the highlights from this year. It’ll help you to remember a couple of lessons learned or inspire you to listen to some episodes (again). We will talk about the following: LeadershipThe look beyond pharmaData scienceBenefit-RiskCareerNonparametricVisualizationProductivityAnd an outlook into 2020 Otherwise, enjoy your Christmas break and we’re taking a week off on New year's eve and start again on the seventh of January. Listen to this episode and become an effective statistician! Merry Christmas!
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Dec 19, 2019 • 41min

CALC Episode 5: You’re hired! How to Fail to be Rejected During the Interview Process

Application process and interview tips with Rhian Jacob and Rachael Loftus Click here to get to the homepage of episode 5
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Dec 16, 2019 • 23min

Baseline testing

A widespread but difficult to treat disease Click this link to go to the homepage of the post. I once reviewed tables for a randomized study and noticed several comments about testing the baseline characteristics. The commenters were arguing which test would be best to test for the differences between the 2 randomized groups at baseline. This made my first angry about the wasted time and then curious about the reasons, statisticians still do this. In today's episode, Benjamin and I discuss some backgrounds for baseline testing in randomized studies. Listen to this episode, share it with others who might learn from it, and be an effective statistician!
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Dec 9, 2019 • 52min

Seeing through the mist - consequences of decisions in phase II

Interview with Trevor Smart Click this link to go to the homepage of this episode! In this episode, Trevor and I discuss a case study to go through the step by step procedure of phase II. We also talk about the following points: What are decision rules?How can we use prior elicitation?What and how do you come to a prior distribution and what is a design prior?What role do relevant and non-relevant differences play here?Any recommended reading?What does the listener need to do differently to make sure, better decisions are made in phase II? Listen to this podcast now!
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Dec 5, 2019 • 31min

CALC Episode 4: Be Significant: What Employers Look for

Want to know how to be the perfect candidate? Click here to get to the homepage of episode 4
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Dec 2, 2019 • 57min

How to leverage time-boxing to reduce overwhelm being a statistician

Batch processing and scheduling tasks to fight procrastination Click this link to go to the homepage of the post. In today's episode, we discuss time boxing and batch processing. We also discuss how these following points work: Schedule your tasks in your calendar Meetings with yourself Combination of smaller tasks Chunks of 15 minutes Can also be applied to meetings (strict agendas) Benefits of the following: Allocate the right amount of time in the right moments (e.g. emails after lunch and hard cognitive SAP writing in the morning) Save space for the important work but also for the necessary managing things (emails, some trainings, …) Avoids overcommitting Relieve your stress levels by having a good way of saying no Better planning on when things will get done really Listen to this episode and share it with others who might learn from it!
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Nov 25, 2019 • 29min

How to get into flow and reach peak performance

Alexander and Benjamin Click this to go to the homepage of this post. This is awesome for everybody, most especially, for brain workers. We also talk about the following points: What is the flowWhy is it importantWhen are we inflowPersonal examplesThe sweet spot between challenge and skillThe role of passionThe role of undistracted time and placeHow to manage distractionsFocus on the tasks as long as possibleBe in the momentEnjoy the experienceKeep practicingAcknowledge the rewardsIndividual vs group flow Listen to this episode now and be an effective Statistician!
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Nov 21, 2019 • 20min

CALC Episode 3: Get a Head Start and Map Your Route to a Career in Drug Development

Discussion with Statisticians Amy Phillips-Jones and Rhian Jacob on practical next steps [Click here to get to the homepage of episode 3]
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Nov 19, 2019 • 44min

What you need to know before you try to increase productivity

Vital tips with Alexander and Benjamin Click this link to go to the homepage of the post. Do you often find your workday spiraling out of control? Do you want to be more productive than you yesterday?Do you want to know how to improve your skill set and work performance?Do you start each day with a plan, but soon become distracted and procrastinating?You are not alone. Sometimes, it’s easier to wait for someone else to tell you what things you should work on rather than to assess yourself. Focusing on continually improving your skill set will boost your confidence and help you become the best version of yourself. In today's episode, Benjamin and I discuss what you need to know to increase productivity: Listen now to be an effective Statistician!

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