Babbage from The Economist (subscriber edition)

DeepMind’s artificial-intelligence system AlphaFold has predicted the three-dimensional shape of almost all known proteins. The company’s boss Demis Hassabis tells us how the AI was able to solve what was, for decades, biology’s grand challenge. Plus, Gilead Amit, The Economist’s science correspondent, explores the significance of the breakthrough for scientists tackling neglected diseases and designing new molecules. The leap forward could be AI’s greatest contribution to biology to date, but how else could machine learning help science? Kenneth Cukier hosts.For full access to The Economist’s print, digital and audio editions subscribe at economist.com/podcastoffer and sign up for our weekly science newsletter at economist.com/simplyscience.

Digital tools and sophisticated wearable devices are being combined with the latest knowledge on metabolic science to build personalised eating plans. Slavea Chankova, The Economist’s health-care correspondent, explores the future of nutrition. Data from new nutrition technology can also be tied to exercise monitoring devices and blood biomarkers, to build algorithms that aim to make people get healthier. But can the emerging personalised nutrition era make a real difference to public health? Alok Jha hosts.Listen to our recent collection of episodes on the digital health revolution at economist.com/babbagewearables.For full access to The Economist’s print, digital and audio editions subscribe at economist.com/podcastoffer and sign up for our weekly science newsletter at economist.com/simplyscience.

The age of quantum computing is coming closer, presenting both an opportunity and a risk for individuals, companies and governments. Host Alok Jha explores why quantum computers threaten to crack the codes that keep data and communications secure over the internet. We also investigate how encryption techniques can be improved for a post-quantum age, and why it is urgent that they be deployed as soon as possible.For full access to The Economist’s print, digital and audio editions subscribe at economist.com/podcastoffer and sign up for our weekly science newsletter at economist.com/simplyscience.

The evolutionary journey that created modern humans was once thought to be relatively linear. But new technology is revealing a far more complex picture. The Economist’s Dylan Barry travels to South Africa to trace the story of our evolution, and explains how interbreeding with other species provided the genes possessed by many people today. To uncover our origins, scientists are nowadays not only hunting for clues in the bones of our ancestors—but in the genomes of living people, too. We speak to the researchers who are helping to rewrite the human story. Alok Jha hosts.For full access to The Economist’s print, digital and audio editions subscribe at economist.com/podcastoffer and sign up for our weekly science newsletter at economist.com/simplyscience.

This week, the Large Hadron Collider returned to life after a three-year upgrade. By recreating conditions as close as possible to the Big Bang, it might provide answers to some of physics’s greatest mysteries. Recent findings have shown chinks in the armour of the Standard Model of particle physics, currently scientists’ best understanding of the universe at its smallest scales. Through the lens of an intriguing anomalous result, host Alok Jha investigates the new theories that might supersede the Standard Model. How could such ideas impact our comprehension of the universe and what it contains?This episode follows our two-part series about the reopening of the Large Hadron Collider. Listen at economist.com/LHC-pod.For full access to The Economist’s print, digital and audio editions, subscribe at economist.com/podcastoffer and sign up for our weekly science newsletter at economist.com/simplyscience.

The energy shock threatens to derail action on climate change. Which technologies will enable the green transition, while ensuring energy security, too? Vijay Vaitheeswaran, The Economist's global energy & climate innovation editor, describes the pathway to a decarbonised future. How can electrical grids be made smarter and more resilient as they are fed by cleaner, more renewable sources of energy? And how soon will the technology that’s needed for the energy transition be ready for widespread deployment? Alok Jha hosts.For full access to The Economist’s print, digital and audio editions subscribe at economist.com/podcastoffer and sign up for our weekly science newsletter at economist.com/simplyscience.

Short-sightedness, known as myopia, was once a rare condition. But in East Asia, it is becoming ubiquitous, with rates increasing in the rest of the world, too. For decades, researchers thought the condition was mostly genetic. But the scientific consensus has changed. Host Alok Jha and Tim Cross, The Economist’s technology editor, wade through the latest evidence and explore how to prevent or slow the onset of myopia. And, how can the condition’s public-health burden be reduced?For full access to The Economist’s print, digital and audio editions subscribe at economist.com/podcastoffer and sign up for our weekly science newsletter at economist.com/simplyscience.

In America and Europe, a growing number of clinics are offering ketamine to treat depression. The anaesthetic—also used illegally as a party drug—can provide rapid relief from the condition where traditional treatments, such as antidepressant drugs, have failed. We investigate how the therapy works, and ask what role it will play in the future of mental-health care. And, as ketamine treatments spread, is enough known about the drug’s long-term safety? Alok Jha hosts with Natasha Loder, The Economist’s health policy editor.For full access to The Economist’s print, digital and audio editions subscribe at economist.com/podcastoffer and sign up for our weekly science newsletter at economist.com/simplyscience.

A new type of artificial intelligence (AI) is rapidly emerging as a candidate to become the next major general-purpose technology. "Foundational AI" will inject itself into many human endeavours—from writing to coding to drug discovery. We explore why foundation models could end up having an economic impact similar to that of electricity, and why the emerging technology is also proving so controversial. Alok Jha hosts.For full access to The Economist’s print, digital and audio editions subscribe at economist.com/podcastoffer and sign up for our weekly science newsletter at economist.com/simplyscience.

Coral reefs are increasingly under threat from global heating, but some species appear to be resistant to warmer sea temperatures. How can scientists harness these findings and revive these important pieces of marine life? Alok Jha hosts.For full access to The Economist’s print, digital and audio editions subscribe at economist.com/podcastoffer and sign up for our weekly science newsletter at economist.com/simplyscience.Additional audio courtesy of the Acoustical Society of America and the U.S. Naval Undersea Warfare Center Newport.