Big Questions with Cal Fussman

Cal talks with the man who evolved from drinking a six-pack of Coca Cola every day as a boy to the author of Superlife: the 5 Simple Fixes that will make you healthy, fit and eternally awesome. Darin is also the co-host of the television show Down to Earth with Zac Efron, where the two go adventuring around the world to find healthy and sustainable ways to live. You may eat a little differently after listening to this conversation.

Listen to some amazing surgery stories this week about what it’s like to operate on a child’s brain from Dr. Jay Wellons, a pediatric neurosurgeon at the Monroe Carell Jr. Children’s Hospital at Vanderbilt and the Vanderbilt University Medical Center. Jay is a gifted writer as well, as anybody who’s read All That Moves Us can attest. Once the harrowing stories are told, Cal asks the neurosurgeon how he stays healthy amid the persistent tension. It’s a question that probably applies to everybody who’s worked in healthcare during COVID, and it calls for everybody’s attention.

Morphogenesis has an immunotherapy treatment that has worked in five out of five clinical trials on skin cancer and it’s nasty cousin, Merkel Cell cancer. The company’s CEO, Dr. James Bianco, says that the treatment may work against any cancer. But he doesn’t want anyone calling it The Cancer Vaccine. Cal gets some insight into the potential breakthrough, and the leaps we’re making in the fight against cancer. If you know someone who’s been touched by cancer, check this episode out. That means everybody.

​​Rich Palarea’s introduction on Twitter reads: “I won’t sleep until I fix $ waste in healthcare.” Cal listens to the story of how Rich became CEO of Kermit, a company that uses technological transparency to reduce costs on surgical implants for hospitals. The conversation reveals how little we know about what goes on behind the scenes in some operating rooms. It also gives us hope that applying transparency across all aspects of healthcare will make life better for everyone. 

Cal takes a moment to pause and reflect on moments he had with two icons who said farewell recently in very different ways. Tennis great Serena Williams ended one of the most impactful careers in the history of any sport at the U.S. Open and the man who lifted The Iron Curtain, Mikhail Gorbachev, took his final breath at the age of 91. Cal tells two stories that showcase the origin of their influence. They both revolve around hugs. We should all take note.

Cal takes a moment to honor those impacted by the attack on the World Trade Center that killed more than 3,000 people in 2001. He replays his conversation with Michael Wright, who was working on the 81st floor on the morning the planes struck. When Michael made it down to the street, one of the twin towers collapsed on his head. Cal replays Michael’s vivid description in this episode for two reasons. So that we’ll never forget the day, as well as to alert us to the terrorist threat of this era: Fentanyl. This synthetic opioid is 50 times more powerful than heroin and much more inexpensive to produce. It’s responsible for the death of more than 200,000 people in the USA over the last two years. 9/11 is a poignant alert that something needs to be done about Fentanyl. Now.

Many people have avoided going to the doctor during the time of Covid . . . unless they had Covid. This may have resulted in missing an early detection of cancer. So this podcast is a reminder to all those who’ve delayed checkups to make an appointment. Cal gets an exam, and now has peace of mind. He also puts the podcast to a checkup. Marketing guru Jason Harris, the CEO of the creative agency Mekanism, enters the conversation to show Cal that it’s time for Big Questions to grow to wear many hats. Cal responds by setting in motion a non-profit to attack problems in healthcare. The Best Is Yet To Come. Thanks for coming on the journey.

Cal has spent his life writing stories and telling them on stage. Big Questions started after he told stories for three straight hours on Tim Ferriss’s podcast. But Cal finds a new power in storytelling through Harvard’s Annie Brewster, a physician who used her own story to help heal herself after being diagnosed with multiple sclerosis roughly twenty years ago. Annie went on to start a non-profit to help others understand their health problems through storytelling, and this conversation gives Cal the seed of an idea . . . and may help you, too.

Until this week, Cal never knew that more than ten percent of the people who signed the Declaration of Independence in 1776 were physicians. Doctors are now found in tech roles that can bring exponential improvements to the masses. Amazon’s Adam Glasofer is a great example.

Johnny Crowder is motivation to all when it comes to changing the way you think about your health. He’s actually rewired his brain to get the best possible behavior from himself. His life is an extreme example of overcoming mental health problems. But the work he’s put in to understand the human brain can be used by anybody who needs to overcome ANY problem.