In this part 2 of EM Cases Journal Jam podcast on Thrombolysis and Endovascular Therapy for Stroke Justin Morgenstern, Rory Spiegel and Anton Helman do a deep dive into the world's literature on endovascular therapy for stroke. While the evidence for endovascular therapy is stronger than that for IV systemic thrombolysis for stroke outcomes at 90 days, a closer look at the literature reveals that a very small minority of patients are eligible for endovascular therapy and we still don't know which patients benefit most from endovascular therapy...

In this two part EM Cases Journal Jam podcast Justin Morgenstern, Rory Spiegel and Anton Helman do a deep dive into the world's literature on systemic thrombolysis for ischemic stroke followed by an analysis of endovascular therapy for stroke. We elucidate the important issues related to p-values, ordinal analysis, fragility index, heterogeneity of studies, stopping trials early and conflicts of interest related to this body of evidence. While "calling a code stroke" is now considered standard for most stroke patients and tPA for stroke is considered a class 1A drug, a close look at the literature tells us that the evidence is not as strong as our stroke protocols suggest...

Dr. Mike Betzner discusses managing acute renal failure with volume overload in remote areas without dialysis. He explores solutions like nitroglycerin, BiPAP, phlebotomy, and rotating BP cuffs. Challenges include hyperkalemia and survival during transport.

Quick and insightful reviews of 17 important adult and pediatric emergency medicine studies from 2016: The PROCAMIO study for stable VT, platelets for head bleeds (PATCH), BP lowering in ICH (ATACH II), antibiotics for abscesses, work up of subarachnoid hemorrhage, dosing IV ketorolac, the PESIT trial, ketamine dosage for sedation in pediatrics, instructions after minor head injury, Salter-Harris I fractures of the lateral malleolus, interpreting oxygen saturation for disposition making in children with bronchiolitis, clinical pathways in pediatric asthma and sepsis and more...

Exploring the challenging diagnosis of euglycemic DKA caused by newer diabetes medications. Understanding the mechanism and risks associated with SGLT2 inhibitors. Distinguishing alcoholic ketoacidosis from euglycemic DKA. Discussing the treatment of euglycemic DKA and the importance of recognizing symptoms in patients on certain medications.

Management of the pediatric trauma patient is challenging regardless of where you work. In this EM Cases episode, with the help of two leading pediatric trauma experts, Dr. Sue Beno from Hospital for Sick Children in Toronto and Dr. Faud Alnaji from Children's Hospital of Eastern Ontario in Ottawa we answer such questions as: what are the most important physiologic and anatomic differences between children and adults that are key to managing the trauma patient? How much fluid should be given prior to blood products? What is the role of POCUS in abdominal trauma? Which patients require abdominal CT? How do you clear the pediatric c-spine? Are atropine and fentanyl recommended as pre-induction agents in the pediatric trauma patient? How can the BIG score help us prognosticate? Is tranexamic acid recommended in early pediatric trauma like it is in adults? Is the Pediatric Trauma Score helpful in deciding which patients should be transferred to a trauma center? and many more...

Airway management requires a lot things; it requires not only technical skills and specific considerations of anatomy and physiology but a co-ordinated team who can communicate clearly and react to a whole slew of potentially challenging situations. On this month's Best Case Ever podcast we use the framework of a new mnemonic PREPARE to discuss human factors, situational awareness and some airway tips and tricks with intensivist Peter Brindley, human factors expert Chris Hicks and EM-intensivist Sara Gray...

Unnecessary antibiotic treatment for UTIs is common due to over-diagnosis and misinterpretation of urinalysis results. The podcast explores the importance of appropriate management and judicious antibiotic use. It discusses the significance of history and physical examination for diagnosing UTIs and the challenges in interpreting urine cultures. The accuracy of self-diagnosis is compared to medical tests, and alternative treatment options are explored. The chapter concludes with the discussion of treatment options for lower UTIs, prevention of recurrent UTIs, and the limitations of sensitivity sheets.

Exploring a case of a patient with a complicated anion gap metabolic acidosis, discussing the controversy around using sodium bicarbonate, the indications for fomepizole, and the importance of building a therapeutic relationship with ED patients. Also covers the initial steps in managing severe renal failure and metabolic acidosis, the lack of evidence supporting bicarbonate use, treatment of hyperkalemia and anion gap metabolic acidosis, and the potential causes of anion gap metabolic acidosis.

I remember when I started practicing emergency medicine a decade and a half ago it seemed that any kid who came to our ED in cardiac arrest died. I know, depressing thought. But, over the past 15 years, survival to discharge from pediatric cardiac arrest has markedly improved, at least for in-hospital arrests. This is probably mostly due to an emphasis on high-quality CPR and advances in post-resuscitation care; nonetheless the more comfortable, knowledgeable and prepared we are for the always scary critically ill pediatric patient, the more likely we will be able to resuscitate them successfully - which is always a huge save.