

Angel Invest Boston
Sal Daher
In the Decade of Biotech when there will be myriad opportunities to invest in angel-scale biotech startups. After decades of angel investing, I am focusing on the life science side of my portfolio and invite other angels to do the same. Here's why: https://www.labcoatventures.com/why-we-are-focused-on-early-stage-biotech/
I’m Sal Daher, host of the Angel Invest Boston Podcast. After immigrating to Boston as a child and attending Belmont High School, I studied engineering at MIT and Stanford. Decades of work in international finance followed. During that time, I invested in a handful of ventures founded by friends and acquaintances. Now, I’m a member of Walnut Ventures and MIT Angels and spend most of my time as an angel investor. Startups in my portfolio include: SQZ Biotech, Gelesis, Akili Interactive, Vedanta Biosciences, FineTune Learning, Concrete Sensors, Squadle, doDoc, Pixability, Mavrck, Viral Gains, Streamroot, XMOS, Alice's Table and others. Exits include: Exos (Microsoft), Rifiniti (KKR) and PIKA Energy (Generac).
I’m Sal Daher, host of the Angel Invest Boston Podcast. After immigrating to Boston as a child and attending Belmont High School, I studied engineering at MIT and Stanford. Decades of work in international finance followed. During that time, I invested in a handful of ventures founded by friends and acquaintances. Now, I’m a member of Walnut Ventures and MIT Angels and spend most of my time as an angel investor. Startups in my portfolio include: SQZ Biotech, Gelesis, Akili Interactive, Vedanta Biosciences, FineTune Learning, Concrete Sensors, Squadle, doDoc, Pixability, Mavrck, Viral Gains, Streamroot, XMOS, Alice's Table and others. Exits include: Exos (Microsoft), Rifiniti (KKR) and PIKA Energy (Generac).
Episodes
Mentioned books

Oct 12, 2022 • 55min
Mark Ribeiro - Private Equity 101
Angel Scale Biotech: Learn More Mark Ribeiro is managing partner at Juna Equity Partners in NYC, a growth equity firm that grew out of part of GE Capital. Since one of my portfolio companies was acquired by a growth equity firm, I thought it would be fun to learn more about this type acquirer. Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson. Highlights: Sal Daher Introduces Mark Ribeiro Angel Investing Vs. Private Equity What Juna Equity Partners is Looking For "... They basically provide autistic learning centers for kids that have been identified at an early age with autism. It's a company that when we bought it, it was still considered a somewhat niche space ... There was a change in the macro environment..." "... what private equity does is it allows companies to become more efficient, and it makes American companies, absolute world beaters..." Private Equity Investments Gone Wrong Advice to the Audience "... This is what angels do. Angels look at founder flesh. They evaluate founder flesh. The other thing is, is this a technology that has the potential to revolutionize an existing business somewhere? ..." Why Staying a Private Company is Better than Going Public Topics: boards, angel investing strategies, management

Oct 5, 2022 • 37min
Eric Greenspan - Smart Insoles
Angel Scale Biotech: Learn More As a practitioner working with foot injuries, Eric Greenspan became so excited about the potential of the smart insole developed by startup IWS that he joined the team. Great chat about the promising field of connected devices in healthcare. Walking six miles per day gives me a strong appreciation for Eric’s work. Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson. Highlights: Sal Daher Introduces Eric Greenspan What Innovative Wellness Systems (IWS) is Solving "... What we're really offering patients is peace of mind..." "... It helps the podiatrist document the value of their orthotics..." "... This is not a diagnostic tool. This is a monitoring device..." Innovative Wellness Systems' Founding Story How Eric Greenspan Became an Entrepreneur The Team Roles at IWS Advice to the Audience Topics: biotech, founding story, product

Sep 28, 2022 • 36min
Alicia Tulsee - Moxie Scrubs
Angel Scale Biotech: Learn More Nurses were a big part of the frequent medical care Alicia Tulsee’s family needed. This led to conversations about how uncomfortable, expensive and ill-fitting were the work clothes available to nurses. Moxie Scrubs was founded to solve that problem. Don’t miss this great conversation with a compelling founder. Highlights: Sal Daher Introduces Alicia Tulsee Moxie Scrubs: What It's Solving "' ... no one's created a brand for nurses and nurses have been shopping online since they received their first paycheck. This the future of the market ... '" The Future of Moxie Scrubs Alicia's Immigrant Founder Story "... I actually started my first business at 19 ... Going online and early days of eBay, I found wholesalers that were selling costume jewelry and purses and handbags and things like that. I said, "Oh, man, if I can buy this stuff and resell it, I can make more money than what I would be earning on an hourly wage at the mall ...'" Advice to the Audience Topics: discovering entrepreneurship, founding story, product

Sep 21, 2022 • 42min
Yun Rhie, Minwoo Jung, and Minjun Kim - WittGen Bio
Angel Scale Biotech: Learn More Yun Rhie, Minwoo Jung, and Minjun Kim are the founders of WittGen. The company is working with AI to create a more efficient platform for treating cancer, a field which tends to have a lower treatment success rate due to its complexity. Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson. Highlights: Sal Daher Introduces Yun Rhie, Minwoo Jung, and Minjun Kim "... The problem you have is that you have to figure out what kind of a tumor you have in order to treat it, to have the right medication to treat it...." Looking Ahead at What's to Come for WittGen "... Using sequencing of the RNA, which tells you what genes are being expressed and being triggered, and then you can look at that and then compare that to samples of the cells, looked at in the microscope and so on..." What Sets WittGen Apart How the Team Came to Be Topics: robotics/AI, biotech, founding stories

Sep 14, 2022 • 50min
Saeid Gholami - iCareBetter
Angel Scale Biotech: Learn More Seeking to match endometriosis patients with doctors most capable of treating the disease, Dr. Saeid Gholami founded iCareBetter. With a background in primary care, Saeid now works with AI to find better solutions to this issue and spread awareness of its importance. Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson. Highlights: Sal Daher Introduces Dr. Saeid Gholami iCareBetter: Finding a Solution for Endometriosis Peer Review: The Vetting Process for Endometriosis Surgeons How Endometriosis Affects Patients' Daily Lives How iCareBetter Started Out “...When we nail the model for endometriosis, then we focus on complex diseases which need multidisciplinary highly specialized care, replicate the model for their diseases…” How Saeid Gholami Came to the U.S. The Immigrant Superman Effect Advice to the Audience Topics: robotics/AI, founding story, discovering entrepreneurship

Sep 7, 2022 • 50min
Sherine Abdelmawla - Akanocure
Angel Scale Biotech: Learn More Sherine Abdelmawla, PhD, founded Akanocure Pharmaceuticalsto combine chemistryand AI in a platform for discovering effective drugs that can be easily produced at scale. The first use case is a cancer therapy. Great chat with a compelling founder. Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson. Highlights: Sal Daher Introduces Sherine Abdelmawla What Akanocure Pharmaceuticals is Doing "... The challenge is ... logistically speaking, manufacturing antibodies, they have problems with pharmacokinetics. Can we have a small molecule that can do the job of that antibody? ..." Collaboration in the Lab Vs. Collaboration in the Field The Business Model for Akanocure "... interrupting the process that the cancer uses for hijacking the production of lipid fats to create its own version, a lipid shell that has particular features that make it really hard to detect the cancer..." Sherine's Backstory Why Research? “...Science is hard enough, but on top of it, doing science with inadequate resources…” Advice to the Audience Topics: biotech, founding story, robotics/AI

8 snips
Aug 31, 2022 • 54min
Jeff Rosen, Founder and VC - Broom Ventures
Jeff Rosen, Founder and VC at Broom Ventures, discusses his favorite portfolio companies and the importance of team, leadership, and culture. They also talk about an AI startup called Writesonic and its ability to generate high-quality content. Another interesting topic is a Boston startup, Tive, and its innovative supply chain tracking solution. Finally, they touch on the challenges faced by math teachers and the concept of secondary liquidity in the stock market.

Aug 24, 2022 • 33min
Ryan Eriksen, Annie Bernard, Malav Sukhadia - Cool Way to Clean Solar Panels
Angel Scale Biotech: Learn More CEO Ryan Eriksen and CTO Annie Bernard founded Sol Clarity, with the help of Malav Sukhadia, to develop a way to clean solar panels in areas where water is limited. It uses static electricity to remove dust and debris, while lowering the carbon footprint and using minimal energy. Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson. Highlights: Sal Daher Introduces Ryan Eriksen, Annie Bernard, and Malav Sukhadia Sol Clarity: Cleaning Solar Panels with Static Electricity Efficient Solar Panel Maintenance with Low Energy Activation "... What we're trying to do with solar energy is to make everything carbon-free, and that purpose is defeated if you're driving around trucks to wash these panels. The EDS can also have a negative carbon print attached to it..." The Decision Process for the Original to Current Designs "... The vision is to have this technology anywhere in the world on any optically clear surface that needs cleaning, and cleaning is a pain point there and water is not available to clean..." Founding Backstories Advice to the Audience Topics: cleantech, co-founders, discovering entrepreneurship, founding stories

Aug 17, 2022 • 44min
Jake Tamarkin, Founder - AI in Life Insurance
Angel Scale Biotech: Learn More Jake Tamarkin’s startup, Everyday Life, uses machine learning to match people who don’t fit the traditional mold of buyers with insurers eager for their business. Jake’s personal experience in buying a life policy surfaced this compelling opportunity. Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson. Highlights: Sal Daher Introduces Jake Tamarkin The Problem Everyday Life Insurance is Solving "... Basically, what they're saying is, if you're poor, you're riskier, because of this very blunt instrument that they're using, which is credit score..." What Sets Everyday Life Insurance Apart Everyday Life's Founding Story Why People Don't Want to Talk About Life Insurance "...We basically pivoted out of banks and into insurance companies and that's been going much better..." How Jake Tamarkin Came to Life Insurance Advice to the Audience Topics: founding story, discovering entrepreneurship, software

Aug 10, 2022 • 46min
Marc Cote: Founder & Angel
Angel Scale Biotech: Learn More Life science founder and angel investor, Marc Cote, discusses his experience in investing, as well as developing startups. He has valuable thoughts for founders and investors. Sponsored by Purdue University entrepreneurship and Peter Fasse, patent attorney at Fish and Richardson. Highlights: Sal Daher Introduces Marc Cote Marc Cote’s Founding Experience “...That's when I joined Boston Harbor Angels, and that was back in 2012. Shortly after we co-founded Synchroneuron saying, ‘What better way to get an investor perspective, than actually sit with a bunch of investors and actually put some of your own funding at risk?’...” How Synchroneuron Developed The Placebo Effect Vs. the Drug Itself Today’s Treatment for Tardive Dyskinesia “...The model that you had of bringing in a professional CEO doesn't exist anymore. Right now, the market for biotech executives is so strong…” The Challenge of Attracting Talent to Startups Advice to the Audience Topics: angel investing strategies, discovering entrepreneurship, founding story