

Angel Invest Boston
Sal Daher
In the Decade of Biotech when there will be myriad opportunities to invest in angel-scale biotech startups. After decades of angel investing, I am focusing on the life science side of my portfolio and invite other angels to do the same. Here's why: https://www.labcoatventures.com/why-we-are-focused-on-early-stage-biotech/
I’m Sal Daher, host of the Angel Invest Boston Podcast. After immigrating to Boston as a child and attending Belmont High School, I studied engineering at MIT and Stanford. Decades of work in international finance followed. During that time, I invested in a handful of ventures founded by friends and acquaintances. Now, I’m a member of Walnut Ventures and MIT Angels and spend most of my time as an angel investor. Startups in my portfolio include: SQZ Biotech, Gelesis, Akili Interactive, Vedanta Biosciences, FineTune Learning, Concrete Sensors, Squadle, doDoc, Pixability, Mavrck, Viral Gains, Streamroot, XMOS, Alice's Table and others. Exits include: Exos (Microsoft), Rifiniti (KKR) and PIKA Energy (Generac).
I’m Sal Daher, host of the Angel Invest Boston Podcast. After immigrating to Boston as a child and attending Belmont High School, I studied engineering at MIT and Stanford. Decades of work in international finance followed. During that time, I invested in a handful of ventures founded by friends and acquaintances. Now, I’m a member of Walnut Ventures and MIT Angels and spend most of my time as an angel investor. Startups in my portfolio include: SQZ Biotech, Gelesis, Akili Interactive, Vedanta Biosciences, FineTune Learning, Concrete Sensors, Squadle, doDoc, Pixability, Mavrck, Viral Gains, Streamroot, XMOS, Alice's Table and others. Exits include: Exos (Microsoft), Rifiniti (KKR) and PIKA Energy (Generac).
Episodes
Mentioned books

Jan 25, 2017 • 1h 9min
Fred Bamber “The Perfect Startup Portfolio” Ep. 5 Experienced Venture Capitalist and Wise Angel Investor
As a venture capitalist Fred Bamber helped build such successful companies as Interleaf, Q1 Labs and Volt Server. Now working as an angel investor Fred is invested in such exciting companies as SQZ Biotech, Pixability, Streamroot and ViralGains. In his self-effacing and modest way, Fred reveals deep wisdom gained from 75 investments in his venture capital career. Here are some of the topics covered: Fred Bamber Finds His Career Path Avoiding the Military Draft Led Him to Work for His First Startup Fred Bamber & Friend Found a Venture Fund – Consulting vs. Venture Capital IPOs Then & Now Investment in Interleaf Makes His First Fund a Success! Two Ways of Connecting in the World of Venture Capital – Via Success & Via Failure Several Losing Investments in Companies Seeking to Exploit the Piezoelectric Effect Themes In Angel Investing – Investing in Brand New Fields i.e. White Spaces ‘…Oracle has a huge go-to-market cost, and engineering is a tiny bit of it.’ Technology Causing Convergence of Consumer & Enterprise Businesses Startups with Jeff Weiss - The Perils of Being Early – Early Augmented Reality (AR) Rich Lane & Reflection Technology – Augmented Reality-like – Projecting Text into the Eye Progress of Technology Is Painful – “Thread Across The Ocean” by John Steele Gordon Michael Lewis & Drama in Business – Paul English & “A Truck Full of Money” Paul English Finds His Inner Entrepreneur after Interleaf Robert P. Smith & “Riches Among the Ruins” – Not Made for Working In Large Companies VCs Should Be Humble Fred Talks About His Investment in Volt Server Uber & Washington, D.C. Cabs Peter Thiel’s Critique of Entrepreneurship – “We Were Promised Flying Cars and We Got 140 Characters” SQZ Biotech & Massachusetts Materials Technology What Fred Looks For In a Startup – Technology, Coachability, Tenacity, Openess – VC vs Angel Startups Should Report Frequently – Reports Should Tie In to Previous Reports i.e. Close the Loop Angel Investor Should Be Father Confessor without the Ave Marias Bettina Hein & Pixability – Example of Determination Combined with Openess Beth Marcus’ Test For Listening Fred Bamber’s Suggestion of the Perfect Number of Angel Investments in a Portfolio Why Sal Daher Is Invested In About 42 Companies The Role of a Board of Directors – Father Confessor Fred’s Favorite Pivot – Q1 Labs (IBM) Fred Also Likes Streamroot’s Pivots Q1 Labs Pivot Runs Counter the Received Wisdom of Startups Needing a Narrow Focus to Succeed “Crossing the Chasm” by Geoffrey A. Moore “Why Knowledge Matters” by E.D. Hirsch, Jr.

Jan 18, 2017 • 1h 3min
Beth Marcus "Startupdoc Is In The House" Ep.4 Startup Founder, Inventor, Advisor and Angel Investor
Dr. Marcus has founded several startups including Exos and Zeemote. The technologies on which her companies are based tend to be widely adopted. Very few inventors can say that their invention is in the hands of ten million people. Beth has those bragging rights. She is a recognized expert in the hand-device interface and has provided strategic advice to leading firms in the space. She is also a highly sought-after advisor to startups with particular understanding of product design and fundraising for technology-based enterprises. Her thoughts can be found on Twitter @StartupDoc. Beth, is a graduate of MIT and Imperial College, London, and continues to be involved with both institutions. She is Entrepreneur In Residence at Imperial College London. In this chatty and candid episode, Beth Marcus imparts some of the hard-earned lessons that can help an entrepreneur turn a defeat into victory. She recounts the story of the remarkable pivot she executed at Exos which led the company from a rout to a very attractive sale to Microsoft. She provides her views on IP strategy, boards of directors, venture capitalists and hiring. Among the luminaries that play a role in the conversation are Bob Metcalfe, Ed Roberts and Pierluigi Zappacosta.

Jan 11, 2017 • 1h 2min
Ben Littauer, Founder, Angel & Advisor - "#1 Fundraising Mistake" - Ep. 3
Ben Littauer travelled an unlikely path from philosophy to communications technology. He brings to life the exciting turns in his careers as founder and angel investor. In his light-hearted style, Ben provides a thoughtful tour of Boston’s angel scene in this episode that ranges over many topics including equity crowdfunding. In particular, he explains what leads founders to make the worst fund-raising mistake of all. The philosopher’s clarity of thought and the engineer’s practicality are in evidence. Sign up at https://www.AngelInvestBoston.com if you want to be made aware of upcoming in-person events. Obviously, this is of particular interest if you are in Boston or environs. You can also follow us on Facebook, LinkedIn and on Twitter @AngelInvestBOS Topics on this podcast: Fundraising Equity Crowdfunding Angel Investing in New England Cornell University Harvard Law School Baranof Software Walnut Venture Associates, Boston Harbor Angels, Launchpad, Comparison & Contrast The Capital Network Mass Challenge Connection between Coding & Philosophy COBOL BBN, Lotus, Lotus 123, Sun Microsystems ARPANET MS Excel VisiCalc, Bob Frankston Mitch Kapor Symantec UNIX Oracle Java MS-DOS, Notework LAN, Local Area Network, Ethernet, Bob Metcalfe EMA, Electronic Messaging Association Paul Graham, Y Combinator Michael Mark Babson College Christopher Mirabile, Ham Lord Angel Treaty Boston vs. Silicon Valley CIC, Cambridge Innovation Center Kickstarter, Indiegogo JOBS Act, Reg CF WeFunder, Mike Norman NetCapital, Troupe Jewelery, Kitsy Lane

Jan 11, 2017 • 1h 3min
Ralph Wagner, Executive, Founder & Angel - "Flunk Calculus, Ace Life" - Ep. 2
Ralph Wagner recalls his journey of self-discovery that led from failure in engineering to incandescent success in marketing and sales. The man who could not do calculus or write code excelled at identifying and exploiting opportunities created by computer technology. In this interview one sees that Ralph’s captivating personality is firmly ballasted by good sense and common decency. It is made evident how his interest in people was vital to the success of his many ventures. If you liked this episode subscribe in iTunes or Google Play so that new episodes will automatically appear in your player. You can find us by searching for Sal Daher or Angel Invest Boston. Do take the time to review us. Sign up at Angel Invest Boston Signup if you want to be made aware of upcoming in-person events. Obviously, this is of particular interest if you are in Boston or environs. You can also follow us on Facebook, LinkedIn and on Twitter @AngelInvestBOS Topics we touched on: Success after flunking calculus IBM Apple Computers Kurzweil Learning Systems, Ray Kurzweil Microsource KeyFile, Jim Stenzel Bob Moll, Moll Associates Arthur D. Little Meditech, Ed Roberts, Neil Pappalardo Michael Mark, Interleaf Steve Watson, Computerland Visicalc, impact of the first spreadsheet software available on a personal computer Rent-a-byte Steve Gaal, TA Associates Tony Helies Walnut Venture Associates, Jim Massarelli, Data General Julian Lange, Visicalc, Software Arts, Babson College Microsoft Excel, Lotus 123 Eyal Shavit, Software Development Corporation, Underware, Brief, Barry Bycoff, Netegrity Stefan Mehlhorn, Permessa, Collego, Loop Pay Jay Singh, Dan Levin, Doron Gan, Tod Loofbourrow, ViralGains Kendall Tucker, Polis, David Solomont

Jan 11, 2017 • 57min
Michael Mark, Super Angel & Founder - "The Best Pivots Ever?" - Ep. 1
In our inaugural episode, angel investing prodigy Michael Mark tells fascinating stories that take us from the precocious founding of his first company to his being a highly-prized investor in hundreds of startups today. The narratives are interwoven with entertaining observations of subjects ranging from comedians to co-founders. Some of the most interesting pivots (radical changes of business plan) are elucidated. Michael’s dry wit and unassuming manner make his deep wisdom accessible to all of us. If you liked this episode subscribe in iTunes or Google Play so that new episodes will automatically appear in your player. You can find us by searching for Sal Daher or Angel Invest Boston. Sign up at AngelInvestBoston.com Sign Up if you want to be made aware of upcoming in-person events. Obviously, this is of particular interest if you are in Boston or environs. You can also follow us on Facebook, LinkedIn and on Twitter @AngelInvestBOS In this conversation we touched on: The best pivots ever! Need for focus When to pivot How frequently business plans work out Hiring a CEO Qualities of the founders Role of luck in startups I What a board of directors can do for the startup How Michael got started in entrepreneurship Pixability Exos Loop Pay Bettina Hein Beth Marcus Will Graylin Progress Software Interleaf Netegrity Underware

Dec 4, 2016 • 3min
Teaser of Episode 3 - Ben Littauer - #1 Fundraising Mistake
This is a teaser of the full, hour-long episode which is still in production. The full episode will be published on January 11th, 2017. Ben Littauer traveled an unlikely path from philosophy to communications technology. He brings to life the exciting turns in his careers as founder and angel investor. In his light-hearted style, Ben provides a thoughtful tour of Boston’s angel scene in this episode that ranges over many topics including equity crowdfunding. In particular, he explains what leads founders to make the worst fund-raising mistake of all. The philosopher’s clarity of thought and the engineer’s practicality are in evidence.

Dec 4, 2016 • 7min
Teaser for Episode 2 - Ralph Wagner - Flunk Calculus, Ace Life
This is a teaser of the full, hour-long episode to be published on January 11, 2017. It contains the full narrative of the events that would propel Ralph to finding his true calling. Ralph Wagner recalls his journey of self-discovery that led from failure in engineering to incandescent success in marketing and sales. The man who could not do calculus or write code excelled at identifying and exploiting opportunities created by computer technology. In this interview one sees that Ralph’s captivating personality is firmly ballasted by good sense and common decency. It is made evident how his interest in people was vital to the success of his many ventures.

Dec 4, 2016 • 7min
Teaser for Episode 1 - Michael Mark - Best Pivots Ever? - Full Episode coming 1/11/17
This is a short teaser of the hour-long Epsiode 1 which will be published January 11th, 2017. This teaser contains the entire narrative of what may be the most dramatic and successful pivot ever. In our inaugural episode, angel investing prodigy Michael Marks tells fascinating stories that take us from the precocious founding of his first company to his being a highly-prized investor in hundreds of startups today. The narratives are interwoven with entertaining observations of subjects ranging from comedians to co-founders. Some of the most interesting pivots (radical changes of business plan) are elucidated. Michael’s dry wit and unassuming manner make his deep wisdom accessible to all of us.

Dec 1, 2016 • 4min
Angel Invest Boston Episode 0 - Brief Intro to Angel Investing & Boston Startup Scene
In Episode 0 host Sal Daher explains the purpose of the podcast. He makes the point that angel investing is more accessible than most people suspect. He talks about Boston’s great ecosystem for startups and angels. In conclusion, he tells a bit about his background and how he got into angel investing. If you liked this episode subscribe in iTunes or Google Play so that new episodes will automatically appear in your player. You can find us by searching for Sal Daher or Angel Invest Boston. Sign up a AngelInvestBoston.com if you want to be made aware of upcoming in-person events. Obviously, this is of particular interest if you are in Boston or environs. You can also follow us on Facebook, LinkedIn and on Twitter (@AngelInvestBOS)