

Nice Genes!
Genome BC
From healthcare and biotechnology to forests and fisheries, the evolving study of genomics is leading to some of the most exciting and world-changing discoveries in science and medicine. Like – did you know that your individual genomic signature can help determine the healthcare treatment you receive? Or that mapping the genomes of trees can inform forest management?
But while the study of genomics holds great promise for the health of people, animals, and the environment, it also confronts us with big questions: How do we study genetic patterns in a way that respects sensitive genetic information, history, and equity? How do we use the power of genomic research to fight climate change? Save the salmon?
Join Dr. Kaylee Byers – a self-described “rat detective” and science communicator as she guides you through fascinating conversations about the what, the why, and the how of genomics.
But while the study of genomics holds great promise for the health of people, animals, and the environment, it also confronts us with big questions: How do we study genetic patterns in a way that respects sensitive genetic information, history, and equity? How do we use the power of genomic research to fight climate change? Save the salmon?
Join Dr. Kaylee Byers – a self-described “rat detective” and science communicator as she guides you through fascinating conversations about the what, the why, and the how of genomics.
Episodes
Mentioned books

Dec 13, 2022 • 0sec
Germ Spotting
Scientists discuss the potential dangers of ancient viruses being released from the Arctic permafrost due to climate change. They explore the challenges of tracking and understanding the evolution of diseases. The podcast emphasizes the importance of data sharing, collaboration, and proactive measures in disease preparedness.

Nov 29, 2022 • 0sec
Cracking the Coral Code
Dr. Shayle Matsuda, a marine biologist, discusses the effects of environmental stresses on coral reefs. Acoustic inventions and genomics are explored to restore and monitor coral reefs. The significance of kelp forests, coral diversity, and collaborative efforts in conservation are also discussed.

Nov 15, 2022 • 0sec
Calls from the Deep
This podcast explores the mysteries of the ocean depths, including the unique songs of whales and their cultural exchange. It delves into the quest to find the 'Loneliest Whale' and the artistic creations inspired by its story. The impact of increased noise on marine mammals and their evolutionary history are also discussed.

Oct 31, 2022 • 0sec
The Devil’s in the Details
In this Halloween-inspired episode, they explore de-extinction and the resurrection of extinct species. They discuss the history and extinction of the Tasmanian tiger, efforts to save Tasmanian devils from extinction and reintroduce them to the wild. They also delve into the use of genomics in understanding diverse species, the origins of the Thylocene project, and the importance of conservation genetics in protecting the planet.

Oct 18, 2022 • 0sec
Pizzly Bears, anyone?
Protecting Local Wildlife Icons
What do you get when you cross a polar bear and a grizzly… and why should you care?In this episode of Nice Genes!, host Dr. Kaylee Byers and National Geographic explorer Dr. Christine Wilkinson look into the mysterious case of pizzly bears, a rare hybrid between polar bears and grizzlies. Together they speak with Dr. David Paetkau, whose team unravelled this strange genomic crossbreeding after receiving more and more sightings coming from the Arctic Circle. Is this hybridization occurring because of climate change? They also speak with Wiuikinuxv scientist Jennifer Walkus, who gained local notoriety for her efforts in ending the trophy hunt of grizzly bears in British Columbia.
Special thanks to Gaelen Krause, Captain of the Island Odyssey with Bluewater Adventures and Ellie Lamb, Naturalist and Hiking Guide.Click here for this episode's Learn-A-Long!Resources:1. Lions, tigers, and Whatsitbears | zoohistories.com: 2. Recent Hybridization between a Polar Bear and Grizzly Bears in the Canadian Arctic | JSTOR3. Arctic hybrids not a good sign, warn scientists | Canadian Broadcast Corporation (CBC)4. "Bears Teach Us" -- Sharing With All Our Relations | Watershed Sentinel 5. DNA analysis of grizzly bears aligns with Indigenous languages | raincoast.org: 6. How Indigenous Knowledge is helping to protect Canada's grizzlies | National Geographic7. Pizzly or grolar bear: grizzly-polar hybrid is a new result of climate change | The Guardian8. Province ends controversial grizzly bear trophy hunt | Global News9. Glacial ice supports a distinct and undocumented polar bear subpopulation persisting in late 21st-century sea-ice conditions | Science10. Sockey salmon collapse due to lack of food, study says | Canadian Broadcast Corporation (CBC)11. One Health Basics | Centers for Disease Control and Prevention: See omnystudio.com/listener for privacy information.

Sep 27, 2022 • 0sec
Welcome to 'Nice Genes!' Season 2
Species loss, warming temperatures, and pollution are just the tip of the iceberg concerning the challenges of climate change. Oh, and you can forget about that iceberg... because it's melting too. The point is, it's easy to feel down on our luck on this planet we all know and love. But what if we don't have to feel that way?On Season 2 of Nice Genes! we look into the incredible science, bold missions, and brainy ideas that give us hope for the spinning rock we call home. Through tools like genomics and confronting big ethical questions, we can see a glimmer of a brighter tomorrow.See omnystudio.com/listener for privacy information.

Aug 16, 2022 • 42min
Cold Case
Dr. Kaylee Byers investigates the 70-year-old 'Babes in the Woods' cold case, using genomic science to bring justice. The ethical implications of law enforcement accessing personal genomics are explored. Genetic genealogy helps solve a double murder cold case, raising questions about public response to DNA use in forensic genealogy. The discovery and identification of the Dalton children sheds light on privacy practices and potential suspects. The hosts discuss the plausibility of the mother being the culprit and acknowledge guest speakers.

Aug 2, 2022 • 0sec
Nodding our Tusks to Heroic Mutations
Just like any good superhero comic, we start this episode with the science going incredibly wrong. Think: vats of toxic waste producing evil mutants that ravage the city. Or maybe not so evil. It really depends on your perspective. Just like the X-men, genetic mutations get a bad rap in the public eye. But they aren’t all nasty.Dr. Kaylee Byers speaks with data scientist and evolutionary biologist Dr. Brian Arnold on how the genetic ‘mistakes’ known as variants occasionally encode incredible abilities. Odd elephants, immortality hiding in our ocean depths, and Rogue-ish bacteria are just a few examples. Dr. Arnold defends these genetic anomalies, and explains how they can make a huge difference to the future of humanity and life on this planet. Also joining us is marine biologist Dr. Maria Pia Miglietta, who shares an incredible ability sitting in our ocean depths. Immortality.So strap on your capes, because we’re heading straight into the strange terrain of “heroic mutations.” Listen to Nice Genes! wherever you get your podcasts, brought to you by Genome British Columbia.Check out this episode's Learn-A-Long at the following link: https://bit.ly/3bey4XT
Resources:
Genetic Mutation - Nature
Genomic mutation rates: What high-throughput methods can tell us
Shane Campbell Staton Group - Tuskless Elephants
Ivory poaching and the rapid evolution of tusklessness in African elephants - Science
Real-Life X-Men: How CRISPR Could Give You Superpowers in the Future - synthego.com
Indonesian divers have evolved bigger spleens to hunt underwater - Science
Mutations may reveal how Tibetans can live on world's highest plateau - Science
The Immortal Jellyfish - American Museum of Natural History
Cellular reprogramming and immortality: Expression profiling reveals putative genes involved in Turritopsis dohrnii’s life cycle reversal
Transcriptome Characterization of Reverse Development in Turritopsis dohrnii (Hydrozoa, Cnidaria)
Horizontal gene transfer and adaptive evolution in bacteria - nature reviews microbiology
Horizontal gene transfer overrides mutation in Escherichia coli colonizing the mammalian gut - PNAS
The Ship of Theseus Dilemma - Open Okstate
See omnystudio.com/listener for privacy information.

Jul 19, 2022 • 44min
Decoding Ancestry
Race is not genetic.TW: racism, systemic racismWhat exactly is the relationship between race and genetics? And where do concepts of ancestry and identity enter the conversation? In the realm of genomics, these are myths waiting to be busted.“What does the information stored in our genomes tell us about our past and our present?” Dr. Kaylee Byers and Co-host Dr. Shawn Hercules join forces to break into this fundamental question of science, ancestry and race. First, they speak with “Genet-SIS” and Executive Producer of the podcast In Those Genes, Dr. Janina Jeff (A.K.A. “Dr.J²”) about how race is really a social construct. Together, they delve into the important distinctions we must make between ancestry and race in order to better understand our biology. Dr. Hercules discusses their research into advanced breast cancer in Caribbean and West African women and how it relates to hereditary genes. This opens the conversation up to how scientists need to be mindful when working with marginalized communities to extract genetic information. Finally, globe-trotting scientist and ancient DNA expert Dr. Eske Willerslev, shares stories of his intercultural journeys to understand human ancestry and migration around the world. Join us for this fascinating episode about race, ancestry, and genomics without borders.Listen to Nice Genes! wherever you get your podcasts, brought to you by Genome British Columbia. Check out this episode's Learn-A-Long at the following link: https://bit.ly/3zgWKrS
Resources:
Analysis of the genomic landscapes of Barbadian and Nigerian women with triple negative breast cancer, Dr. Shawn Hercules
In those Genes Podcast, Dr. Janina M. Jeff
Eske Willerslev Is Rewriting History With DNA, The New York Times
The Ancestry and affiliations of Kennewick Man, nature
Racial bias in a medical algorithm favors white patients over sicker black patients, The Washington Post
The promise and peril of the new science of social genomics, nature
How Science and Genetics are Reshaping the Race Debate of the 21st Century
Sam Harris, Charles Murray, and the allure of race science
Social Genomics and the Life Course: Opportunities and Challenges for Multilevel Population Research
Race, Ethnicity, and Genomics: Social Classifications as Proxies of Biological Heterogeneity
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Jul 5, 2022 • 44min
The Invisible Footprint
How the hunt for wild species leads to eDNAMost of us have a hard-enough time looking for our cell phone chargers in the dark. So imagine trying to find something that’s hidden high in building rafters, deep in muddy bogs, or scattered across endless savannahs. And now, imagine the thing you’re looking for has fangs… and sharp claws.Dr. Kaylee Byers and her wing-woman Dr. Cylita Guy, call-in wildlife conservationist Gabi Fleury to assist in answering, ‘How do you find that which doesn’t want to be found? And should you?’ Globally speaking, does our need to turn over every rock to find vulnerable species really intersect with conservation? Rats, bats, and cheetahs weasel their way into this exciting conversation on how the study of genomics may be the “hopping off point” into a more sustainable future.Also joining us is world famous DNA scientist, professor and globe-trotting adventurer Dr. Eske Willerslev, sharing the secret weapon he pioneered to find some of the world’s most elusive creatures.Listen to 'Nice Genes!' wherever you get your podcasts, brought to you by Genome British Columbia. Check out this episode's Learn-A-Long at the following link: https://bit.ly/3QlLVue
Resources:
Dr.Cylita Guy, Science Storyteller and Educator
Spot the Species, game
Gabi Fleury - Conservationist, technologist, Researcher
What is eDNA
Dr. Eske Willerslev, DNA Scientist, Professor and Director of University of Copenhagen’s Centre of Excellence GeoGenetics
Diverse Plant and Animal Genetic Records from Holocene and Pleistocene Sediments, Science
Identifying twice as many species with eDNA, Canadian Journal of Fisheries and Aquatic Sciences
Going out for dinner—The consumption of agriculture pests by bats in urban areas
Book: Chasing Bats and Tracking Rats: Urban Ecology, Community Science, and How We Share Our Cities
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