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Democrats hope to have a deal on their spending plan by the end of the week. POLITICO’s Anthony Adragna breaks down which provisions are facing the chopping block as the party tries to win over moderates. Plus, Treasury Secretary Janet Yellen expects inflation to linger into next year. And the CDC’s Rochelle Walensky says you can trick-or-treat.Anthony Adragna is a Congress reporter and author of Congress Minutes.Jeremy Siegel is a host for POLITICO Dispatch.Irene Noguchi is the executive producer of POLITICO audio.Jenny Ament is the senior producer of POLITICO audio.Raghu Manavalan is a senior editor for POLITICO audio.Read more in Congress Minutes. Learn more about your ad choices. Visit megaphone.fm/adchoices

Ever wonder what it’s like to moderate a debate? POLITICO New York’s Sally Goldenberg shares her experience putting questions to Democratic frontrunner Eric Adams and Republican Curtis Sliwa in their first one-on-one matchup. Plus, the Fed cracks down on trading by top officials. And Gov. DeSantis calls for a special session to fight Biden’s vaccine mandate.Sally Goldenberg is the City Hall bureau chief for POLITICO New York.Jeremy Siegel is a host for POLITICO Dispatch.Irene Noguchi is the executive producer of POLITICO audio.Jenny Ament is the senior producer of POLITICO audio.Raghu Manavalan is a senior editor for POLITICO audio.Read more: Eric Adams is nearly mayor of New York. But first he has to beat this guy. Learn more about your ad choices. Visit megaphone.fm/adchoices

From mixing and matching to what age groups are approved, POLITICO’s Lauren Gardner breaks down the latest on boosters. Plus, the director of the NIH decries unproven Covid origin theories. And California Gov. Newsom signs an order to ease supply chain issues.Lauren Gardner is an FDA reporter for POLITICO.Jeremy Siegel is a host for POLITICO Dispatch.Irene Noguchi is the executive producer of POLITICO audio.Jenny Ament is the senior producer of POLITICO audio.Raghu Manavalan is a senior editor for POLITICO audio.Sign up for the POLITICO Pulse newsletter. Learn more about your ad choices. Visit megaphone.fm/adchoices

The governor’s mansion isn’t the only thing on the line in November. Republicans could also take back control of the State House. POLITICO’s Liz Crampton reports. Plus, Facebook will pay up to $14.3M to settle claims it discriminated against U.S. workers. And DHS Secretary Alejandro Mayorkas tests positive for Covid.Liz Crampton is a state policy reporter for POLITICO.Jeremy Siegel is a host for POLITICO Dispatch.Irene Noguchi is the executive producer of POLITICO audio.Jenny Ament is the senior producer of POLITICO audio.Raghu Manavalan is a senior editor for POLITICO audio.Read more reporting from The Fifty. Learn more about your ad choices. Visit megaphone.fm/adchoices

Federal regulators are letting the cryptocurrency move one step closer to legitimacy. POLITICO's Kellie Mejdrich reports. Plus, the State Department's Inspector General launches investigations into the end of diplomatic operations in Afghanistan. And Trump sues the Jan. 6 committee.Kellie Mejdrich is a financial services reporter for POLITICO.Jeremy Siegel is a host for POLITICO Dispatch.Irene Noguchi is the executive producer of POLITICO audio.Jenny Ament is the senior producer of POLITICO audio.Raghu Manavalan is a senior editor for POLITICO audio. Learn more about your ad choices. Visit megaphone.fm/adchoices

Infrastructure, reconciliation and debt ... oh my! POLITICO's Congress editor Elana Schor breaks down the latest from the Hill. Plus, Transportation Secretary Buttigieg warns some supply chain problems will persist into 2022. And Dr. Fauci tamps down concerns about the Covid booster review process.Elana Schor is POLITICO's Congress editor.Jeremy Siegel is a host for POLITICO Dispatch.Irene Noguchi is the executive producer of POLITICO audio.Jenny Ament is the senior producer of POLITICO audio.Raghu Manavalan is a senior editor for POLITICO audio. Learn more about your ad choices. Visit megaphone.fm/adchoices

President Biden is trying to ease supply chain issues as Republicans latch onto looming shortages ahead of the holidays. POLITICO’s Steven Overly reports. Plus, the FDA’s vaccine panel endorses Moderna’s booster shot for elderly people and others at high risk. And Florida Gov. Ron DeSantis vows to sue the Biden administration over vaccine mandates.Steven Overly cover global trade for POLITICO.Jeremy Siegel is a host for POLITICO Dispatch.Irene Noguchi is the executive producer of POLITICO audio.Jenny Ament is the senior producer of POLITICO audio.Raghu Manavalan is a senior editor for POLITICO audio.Read more: White House scrambles to address looming Christmas crisis Learn more about your ad choices. Visit megaphone.fm/adchoices

President Biden's vaccine mandate is inching its way closer to reality. POLITICO's Rebecca Rainey looks at what'll happen when it takes effect. Plus, the Department of Justice opens a civil rights probe into youth correctional facilities in Texas. And the Education Department settles a union lawsuit over debt forgiveness.Rebecca Rainey is a labor reporter for POLITICO.Jeremy Siegel is a host for POLITICO Dispatch.Irene Noguchi is the executive producer of POLITICO audio.Jenny Ament is the senior producer of POLITICO audio.Raghu Manavalan is a senior editor for POLITICO audio.Read more: Where Biden’s vaccine mandate will hit and miss Learn more about your ad choices. Visit megaphone.fm/adchoices

West Virginia has three incumbent members of Congress. But it’s losing a seat to redistricting. POLITICO’s Ally Mutnick reports. Plus, Southwest and American airlines say their workers will have to get vaccinated despite Gov. Abbott’s order banning vaccine mandates. And a divided Supreme Court considers who can defend abortion restrictions.Ally Mutnick is a campaigns reporter for POLITICO.Jeremy Siegel is a host for POLITICO Dispatch.Irene Noguchi is the executive producer of POLITICO audio.Jenny Ament is the senior producer of POLITICO audio.Raghu Manavalan is a senior editor for POLITICO audio.Read more: 3 members, 2 seats: West Virginia Republicans gird for redistricting showdown Learn more about your ad choices. Visit megaphone.fm/adchoices

Facebook has been in hot water before. But this time could be different. POLITICO’s Alexandra LeVine reports. Plus, 24 countries plan to join a pledge led by the U.S. and E.U. to reduce methane emissions. And Merck asks the FDA for emergency use approval of experimental Covid pill.Alexandra LeVine is a tech reporter for POLITICO.Jeremy Siegel is a host for POLITICO Dispatch.Irene Noguchi is the executive producer of POLITICO audio.Jenny Ament is the senior producer of POLITICO audio.Raghu Manavalan is a senior editor for POLITICO audio. Learn more about your ad choices. Visit megaphone.fm/adchoices