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NPR's Up First is the news you need to start your day. The three biggest stories of the day, with reporting and analysis from NPR News — in 10 minutes. Available weekdays at 6:30 a.m. ET, with hosts Leila Fadel, Steve Inskeep, Michel Martin and A Martinez. Also available on Saturdays at 9 a.m. ET, with Ayesha Rascoe and Scott Simon. On Sundays, hear a longer exploration behind the headlines with Ayesha Rascoe on "The Sunday Story," available by 8 a.m. ET. Subscribe and listen, then support your local NPR station at donate.npr.org.Support NPR's reporting by subscribing to Up First+ and unlock sponsor-free listening. Learn more at plus.npr.org/upfirst
Episodes
Mentioned books

Aug 3, 2025 • 26min
Can Psychedelic Therapy Go Mainstream?
Rachel Carlson, a producer for NPR's science podcast Shortwave, delves into the fascinating world of psychedelic therapy. She shares insights on the promising potential of psychedelics for treating PTSD and depression, while navigating the complex legal landscape that hinders their prescription. The discussion highlights ketamine's unique role and the growing trend of at-home therapies, emphasizing the fine balance between hope and caution in this evolving field. Listeners will find the blend of science and personal experience truly eye-opening.

39 snips
Aug 2, 2025 • 17min
Economic Worries, Redistricting Battles, Reconsidering BMI
Will Stone, an NPR health correspondent, dives into pressing economic and health topics. He discusses disappointing job growth and how immigration and tariffs are impacting the economy. The conversation shifts to the contentious issue of redistricting, highlighting its political implications in states like Texas and California. Stone also critiques the reliability of Body Mass Index (BMI) as a health metric, advocating for alternatives like Bioelectrical Impedance Analysis to provide a more accurate assessment of health risks.

103 snips
Aug 1, 2025 • 13min
Tariffs Deadline, Texas Flood Hearing, Witkoff In Israel
New tariff rates have been introduced, significantly increasing costs on Canadian imports. U.S. officials are in Gaza to oversee humanitarian efforts amidst a critical crisis. A powerful letter from over a thousand rabbis urges Israel to facilitate more aid. The podcast delves into the complex and often divided opinions on the situation in Gaza, highlighting varying perspectives within the Jewish community. The discussion offers a mix of impactful news and insightful analysis on these pressing issues.

66 snips
Jul 31, 2025 • 14min
Fed Keeps Interest Rates, Texas Redistricting, US Middle East Envoy In Israel
The Federal Reserve has decided to keep interest rates steady despite pushback from various political figures. In Texas, lawmakers are proposing redistricting plans to strengthen Republican control. Meanwhile, the U.S. special envoy's visit to Israel unfolds against a backdrop of dire warnings about a humanitarian crisis in Gaza, where famine is looming and casualties are rising. The discussions shed light on the interconnected nature of domestic politics and global humanitarian issues.

103 snips
Jul 30, 2025 • 13min
Gaza Famine and Diplomacy, EPA Emissions Standards, GOP's Epstein Troubles
A humanitarian crisis is unfolding in Gaza, prompting the UK to consider recognizing Palestinian statehood if conditions don’t improve. Meanwhile, the EPA is reversing its stance on carbon emissions regulations, raising alarms about potential impacts on climate change. In a twist of intrigue, Ghislaine Maxwell may offer testimony to Congress about her involvement with Epstein, stirring political concerns within the GOP as they navigate this scandal. These pressing issues reveal complex intersections of geopolitics and public policy.

258 snips
Jul 29, 2025 • 13min
NYC Office Shooting, Trump In Scotland, Gaza Aid Latest
A tragic shooting incident in Manhattan left four dead, including a police officer, sparking chaos and a community in mourning. Meanwhile, President Trump made headlines during his Scotland trip by signing new trade agreements and implementing tariffs. The podcast also sheds light on the evolving humanitarian situation in Gaza, with discussions on aid challenges and shifting perspectives on the ongoing conflict. Tensions rise as media coverage begins to reflect the harsh realities faced by those in Gaza.

93 snips
Jul 28, 2025 • 38min
Pete Buttigieg warns democrats can't go back to pre-Trump status quo
Pete Buttigieg, former U.S. Secretary of Transportation and a notable political strategist, shares candid insights on the Democratic Party's challenges. He discusses the urgent need for Democrats to adapt their strategies post-Trump and restore public trust, emphasizing a populist approach. Buttigieg tackles the complexities of identity politics and advocates for inclusivity. He also reflects on the need for bold policies that resonate with voters while addressing pressing urban issues like housing and clean energy. The discussion balances serious political dynamics with lighthearted humor.

68 snips
Jul 28, 2025 • 13min
Trump In Scotland, Gaza Aid, Pete Buttigieg on Democrats
President Trump made headlines in Scotland with a new tariff deal, amidst protests highlighting public discontent. Meanwhile, the situation in Gaza continues to deteriorate, prompting the Israeli military to announce daily pauses for humanitarian aid. Former Transportation Secretary Pete Buttigieg discusses challenges facing the Democratic Party, emphasizing the need for leadership reform and innovative strategies in the wake of Trump's presidency. A deep dive into these pressing issues reveals the complexities of politics and humanitarian crises.

80 snips
Jul 27, 2025 • 22min
How is Trump Changing the Justice Department?
Ryan Lucas, NPR's Justice Department correspondent, dives into the transformative impact of Donald Trump's reelection on the DOJ. He discusses the shift from independence to alignment with the president's agenda, highlighting the influence of Trump's personal lawyers in reshaping priorities. The conversation touches on controversial prosecutions and the changing landscape of the Civil Rights Division, raising alarms about the potential erosion of justice and civil rights protections. Supporters and critics weigh in on this dramatic pivot in the department's mission.

44 snips
Jul 26, 2025 • 16min
Trump In Scotland, Detainee Abuse Allegations in Florida, Stocks Surging
President Trump’s visit to Scotland is overshadowed by his ties to Jeffrey Epstein and ongoing protests against U.S. policies. Meanwhile, shocking allegations emerge from a Florida detention center, where detainees report inhumane treatment. On a brighter note, the stock market is reaching record highs, defying the anxiety surrounding the economy and trade tariffs. This fascinating juxtaposition of political controversies, human rights issues, and economic optimism makes for a thought-provoking discussion.