Intelligent Medicine

Use of magnesium in Crohn's disease; Study: Association of habitual alcohol intake with risk of cardiovascular disease; If one is taking vitamin C, is a collagen supplement for the skin superfluous?; Is there a good treatment for varicose veins?

The Annatto plant is valued as a rich source of tocotrienols and a novel, newly-discovered nutraceutical: geranylgeraniol (GG). Dr. Barrie Tan, a Ph.D. biochemist who discovered GG, and Dr. David Brady, former director of the Human Nutrition Institute at the University of Bridgeport and author of numerous books and scientific papers, join us to discuss the roles of tocotrienols and GG in human health. Traditional forms of vitamin E supplements—the tocopherols—are being superseded by tocotrienols as more therapeutic forms of vitamin E. Tocotrienols have shown promise in oncology, for supporting liver health, and for protecting cell membranes as potent fat-soluble antioxidants. GG is ubiquitous as a precursor of diverse compounds including CoQ10, active vitamin K, sex steroids, and proteins. It is useful as a general preventive supplement as well as for specific applications like offsetting CoQ10 depletion in statin users, in metabolic syndrome, and for staving off sarcopenia. Drs. Brady and Tan share their experience in dosing Annatto products, which come in a variety of iterations, alone or teamed with other supplements.

Dr. Hoffman continues his conversation with Dr. Barrie Tan, a Ph.D. biochemist who discovered GG, and Dr. David Brady, former director of the Human Nutrition Institute at the University of Bridgeport.

Mast Cell Activation Syndrome (MCAS) is a diagnosis that offers a new way of understanding patients with a wide array of elusive symptoms, resistant to conventional therapy. Dr. Tania Dempsey, an expert in dealing with complex diseases, has performed extensive research in collaboration with Dr. Lawrence Afrin, author of "Never Bet Against Occam: Mast Cell Activation Disease and the Modern Epidemics of Chronic Illness and Medical Complexity." Dr. Dempsey explains the many manifestations of MCAS, which go beyond mere classical allergies, including headaches, psychiatric symptoms, gastrointestinal problems, and even gynecological and urological complaints. Certain medications can help treat it, along with diet and natural supplements like quercetin, DAO, and luteolin. Triggers may include mold, environmental toxins, stress, and tick-borne infections. There’s even speculation that MCAS may be responsible for some of the symptoms of Long Covid.

Dr. Hoffman continues his conversation with Dr. Tania Dempsey, an expert in dealing with complex diseases, about Mast Cell Activation Syndrome (MCAS).

Kim Kardashian sells pricey medically-inappropriate body scans; Berberine for blood sugar? Aftercare for shoulder replacement? Wash your pillowcases to stave off health problems! Sugar—not fat—is the culprit in heart disease; New medical advance may stave off horseshoe crab extinction.

Which supplements should be taken by themselves without food, and which to take in the AM and PM? Pros/cons of hormone replacement therapy for menopause; Natural treatment of rheumatoid arthritis; Covid after non-Hodgkin's disease—is there a concern? Vitamin D scores vs. hard-to-treat cancers; A shocking approach to smoking cessation; 10 reasons why seniors go to ground.

Have you ever experienced that sluggish feeling after a meal and wondered why? Nutritionist Leyla Muedin explores the surprising ways our diet impacts not just our physical health, but our emotions and energy levels too. A recent survey by Daily Harvest throws the spotlight on a staggering fact: a majority of us are unwittingly inviting fatigue and frustration at our dining tables. With 93% of participants linking their food intake to a drop in vitality and a food-induced stupor, it's clear that what's on our plate is doing more than just filling us up.

Risk factors for ALS; Household chemicals inked to brain health risk; Any recommended supplements for microvascular disease?; How does the 'good' bacteria in yogurt actually work? How much should I consume daily?

"Thanks to your recent podcast, I was able to stop taking proton pump inhibitors!"; Drinking coffee may be beneficial in preventing sarcopenia; "I would be in perfect condition at 87 years of age if I didn't smoke when I was younger."; My MCV and MCH on my blood tests are low. Am I anemic?