Intelligent Medicine

Dr. Edward Walker, a scientist from the New Zealand Institute for Plant and Food Research, details the rigorous research process behind Calocurb, a natural product aimed at curbing appetite and fighting obesity. Dr. Walker explains how his team identified and formulated Amarasate, a compound derived from New Zealand hops, which mimics the appetite-suppressing effects of certain gastrointestinal hormones like GLP-1. The conversation also covers the evolution of the product, the scientific studies confirming its efficacy, and practical considerations for its use. They further delve into the challenges and potentials of using natural alternatives to pharmaceutical weight loss drugs.

Dr. Hoffman continues his conversation with Dr. Edward Walker, a scientist and lecturer with The New Zealand Institute for Plant and Food Research Limited, a New Zealand Crown Research Institute. He helped discover and develop Amarasate, the active ingredient in Calocurb.

“5:2” intermittent fasting outperforms diabetes drugs; Celebrity UK diet doc—proponent of intermittent fasting—tragically dies at 67 while hiking mountainous terrain on Greek holiday; Is L-serine good or bad for the brain? What’s the latest on the fish oil/cardiovascular disease controversy? Most Ozempic users quit before attaining weight loss goals; Benefits of Calocurb for weight loss. In turnaround, testosterone NOT found to hike cardio risk; Men with low T suffer early death; CBD chews combat anxiety, joint problems in pets.

“Ultra-Processed Foods DO NOT Cause Obesity” claims latest study from top U.S. diet policy makers; Florida Congresswoman takes aim at high-fructose corn syrup, food dyes in proposed bill; What’s the best natural sunscreen? Why is there DPA in fish oil—and is it beneficial? A caller’s doctor poo-poos vitamin D’s benefits for immunity; Natural support for GERD; Alzheimer’s slowed by lifestyle intervention in first-of-its-kind trial; Campaigns against misinformation backfire—by making people distrust legitimate information; Pentagon funds $450 million experimental project to deliver lab-grown meat to troops to “lower carbon footprint”.

The Connection Between Community Mobility, Exercise, and Cognitive Health. Nutritionist Leyla Muedin weighs in on the impact of community, mobility and exercise on cognitive function and overall health. She reviews recent studies, including one from the Journal of the American Geriatric Society, highlighting how greater community and mobility can be associated with better cognitive function, and another study from the journal Aging Cell that demonstrates exercise’s beneficial effects on brain health at the cellular level in mice. Additionally, Leyla discusses the harmful effects of air pollution on brain health and the importance of a holistic approach, emphasizing both physical activity and healthy lifestyle choices to mitigate cognitive decline and improve well-being.

Mask confusion is reigning in New York; A case of high dose curcumin in the treatment of kidney disease and psoriasis; Nystatin therapy for the treatment of candida.

What kind of sweetener can I use in my daily coffee and tea?; I have an asymptomatic urinary tract infection. Must I take an antibiotic?; I've been on a low carb diet for 16 months. When will my diabetes go away?; I recently had hip surgery and want to take care of my joints. What supplements do you recommend?; Do you have a recommendation for my pet's joint health too?; How can I treat or manage emphysema?

Alex Martinez, CEO and co-founder of Intrinsic Medicine reveals the potential of utilizing human milk biology, specifically the microbiome and human milk oligosaccharides (HMOs), to address various medical challenges such as Parkinson's disease, autism spectrum disorder, irritable bowel syndrome, Alzheimer's disease, and inflammatory bowel disease. Alex shares his journey from being an attorney to starting a therapeutics company focused on the innovative use of human milk's properties. The conversation also delves into the science behind HMOs, their evolutionary significance, and their potential impact on the microbiome and immune system. This episode provides insights into the cutting-edge research and the promising future of natural, less toxic, and cost-effective therapeutic solutions.

Dr. Hoffman continues his conversation with Alex Martinez, the CEO and co-founder of Intrinsic Medicine, a therapeutics company leveraging human milk biology to transform Gut-Immune-Brain Axis (GIBA) disorders such as Parkinson’s, Autism Spectrum Disorder, IBS, Alzheimer’s, and IBD, among other illnesses.

Although cardiovascular disease is usually thought of as a man’s disease, almost as many women die each year of heart problems. Jane Jansen, a naturopathic practitioner from the Tree of Life Wellness Center in Massachusetts brings a unique perspective with her extensive background in cardiovascular labs and non-invasive cardiology. She sheds light on the gender disparities in cardiovascular research, the critical periods for women's heart health, especially during perimenopause and menopause, and the evolving understanding of hormone replacement therapy. The episode highlights the importance of early diagnosis, lifestyle changes such as diet and exercise, and the benefits of specific supplements like aged garlic extract. Jansen addresses the underestimation of women's cardiovascular risks compared to breast cancer and offer practical advice on managing stress and improving sleep quality. This comprehensive conversation aims to break stereotypes and provide actionable insights for better heart health among women.