
The Matt Walker Podcast
The Matt Walker Podcast is all about sleep, the brain, and the body. Matt is a Professor of Neuroscience at the University of California, Berkeley. He is the author of the book, Why We Sleep and has given a few TED talks. Matt is an awkward British nerd who adores science and the communication of science to the public.
Latest episodes

16 snips
Feb 14, 2022 • 12min
#15: Sleep & Weight Gain – Part 1
Matt kicks off a two-part series all about sleep, eating, and weight gain. He starts by introducing two appetite-regulating hormones: leptin and ghrelin. Matt explains how leptin sends a signal of fullness, to your brain. When leptin levels are high, your appetite is reduced, and you feel satisfied by the food you eat. Ghrelin does the exact opposite. It revs up your hunger, so when your ghrelin levels are high, you don’t feel satisfied by the food you ate, so you want to eat more.Matt tells us that when you’re not getting enough sleep, the levels of these two hormones are affected in unfortunate ways, causing you to feel less full and more hungry. Specifically, sleep loss decreases leptin levels by 18%, yet increases ghrelin levels by 28%!So when you are not getting enough sleep, the body losses the fullness signal AND suffers an increase in hunger levels. The combined consequences? Your appetite rockets up!It’s also been discovered that levels of endocannabinoids --a class of cannabinoids we naturally produce ourselves -- increase sharply in response to a lack of sleep. As a result, your hunger levels increase even more (as you may know, cannabinoids are part of the reasons that cannabis gives you the munchies).Adding up all of these effects, Matt describes how this lack of sleep causes people to consistently overeat. Usually somewhere between 250 to 400 extra calories each and every day!Snacking also becomes a problem. For example, if you present a group of people with a large meal of over 1,000 calories, then give them the option to keep snacking, under-slept individuals will continue to snack, consuming an additional 200 to 300 calories relative to those who’ve been getting a full eight hours of sleep.This all begs the question: is there a reason why your hunger goes into overdrive when you are under-slept? Matt explains one plausible theory from an evolutionary perspective, based on the fact that when animals are in a starvation state, the brain keeps them awake longer so they can forage further. Therefore, when the brain doesn’t get enough sleep, it thinks we may be in a state of starvation and increases our desire for food.Finally, notes what's coming in part two: that insufficient sleep not only increases how much you eat but changes your food preferences, and changes how your bodies deposit the extra calories we take on as our hunger increases, relevant to body fat accumulation.Please note that Matt is not a medical doctor, and none of the content in this podcast should be considered medical advice in any way, shape, or form, nor prescriptive in any way.The good people at Athletic Greens are the sponsors of this week’s episode, and they are generously offering three benefits for anyone who uses the above link for their first order: 1) a discount on your order, 2) a one-year free supply of vitamin D, and 3) five free travel packs. Athletic Greens is a nutrition drink that combines a full complement of antioxidants, minerals, and biotics, together with essential vitamins. Matt’s been using it for several years now, first because he’s serious about his health and uses it as a full nutritional insurance policy, and second, because Matt did his research on the science and ingredients in Athletic Greens and thinks it’s science and scientific data that can be taken as ground truth.So, make your way over to Athletic Greens, and take advantage of this incredible deal. And, as always, if you have thoughts you’d like to share, please reach out to Matt on

35 snips
Jan 31, 2022 • 10min
#14: Temperature – Part 2
In the previous episode, Matt described the role of temperature in helping us fall asleep. In this episode, Matt teaches us all about the role of temperature in helping us stay asleep across the night, and then more effectively wake up the following morning.First, Matt takes us back to the body temperature suit experiments that were able to warm or cool different parts of the body. Matt explains that, using this same method, when you continue to cool the body throughout the first and middle parts of the night, enhance the ability of individuals to stay asleep more soundly across the night, increase the amount of deep sleep, and boost the electrical quality of that deep sleep.Matt explains why a warm bath or shower before bed helps you sleep, perhaps for the opposite reasons you think. It is not that you get warm and toasty ready for bed. Instead, when you get out of the bath or shower, all of the blood races to the surface of your skin. As a result, your core body temperature plummets, enabling you to fall asleep faster and stay asleep more easily.Matt also discusses how external ambient room temperature impacts our sleep at night. He notes that the optimal temperature for sleep at night for the average adult is between 16-18 degrees Celsius, or 61-65 degrees Fahrenheit, although everyone will be a little bit different, of course.Finally, Matt explores the effect of temperature on waking up. He notes that as you move into those late morning hours of sleep, particularly as you start to enter the REM sleep-rich phases of your sleep cycle later in the morning, your central brain temperature rises significantly. Indeed, it is in the last 30 minutes before people would naturally wake up in the morning that their body temperature starts to increase markedly. Matt goes on to describe how this increase in temperature is a signal that triggers the beginning of the awakening process.Related to this, Matt notes that waking up can be challenging for many people, especially if you're not sleeping in synchrony with your chronotype. However, Matt suggests that one way you can facilitate the process of waking up more effectively is by trying to warm up the ambient temperature of the bedroom in the last 30 minutes before your alarm goes off. So if you have a smart thermostat, try to program it to increase the temperature to around 21 degrees Celsius or approximately 70 degrees Fahrenheit in the last 30 minutes before your alarm goes off.The bottom line is that many of us don’t realize how important temperature is to falling asleep, staying asleep, and enjoying an enlivened awakening the next morning.Please note that Matt is not a medical doctor, and none of the content in this podcast should be considered medical advice in any way, shape, or form, nor prescriptive in any way.The good people at InsideTracker are the sponsors of this week's episode, and they are generously offering 25% off any one of their programs for anyone who uses the above link. InsideTracker is essentially a personalized biometric platform that analyzes your blood and your DNA to better understand what's happening inside of you and also offers suggestions regarding things that you can do to better try and adjust some of those numbers, optimize them, and, as a result, optimize you.So, make your way over to InsideTracker, and take advantage of this incredible deal on this valuable and remarkably convenient service. And, as always, if you have thoughts or feedback you'd like to share, please reach out to Matt on Instagram.

12 snips
Jan 17, 2022 • 10min
#13: Temperature - Part 1
In today's episode, Matt reveals how 1) your own temperature and, even more precisely, 2) the temperature of different parts of you, as well as 3) the temperature of your bedroom, can change how well or how poorly you sleep at night.Matt describes the basic physiology of how your brain and body needed to drop their core temperature by about 1 degree Celsius, or about 2 to 3 degrees Fahrenheit, for a person to fall and stay asleep across the night. This is the reason why we will always find it easier to fall asleep in a room that's too cold than too hot because the room that's too cold is at least taking you in the right temperature direction for good sleep at night.Matt teaches us that, ironically, one important way to drop your core body temperature is to warm up your extremities, specifically your hands and feet. He explains that it's one of the key ways your body regulates temperature. To drive his point home, Matt points to research showing that if you gently warmed the paws of rats, it encourages the blood to rise to the surface of the skin of those paws, away from the core of the body. By emitting heat away from the body's center, it drops core body temperature rapidly, and as a result, the rats drifted off to sleep far faster than was otherwise normal.Matt complements all this with a study in humans using a whole-body temperature sleeping suit, a little like wetsuit, but with tubes throughout that can warm or cool different parts of the body with warm or cool water. In the first series of studies, researchers selectively warmed the feet and the hands by just a small amount, which caused a rising of the blood to the surface of the skin. As they warmed the body's extremities, the core temperature of the participants dropped, and the upshot was that these healthy individuals were falling asleep 20% faster than was normal.In the second round of studies, even more remarkable, if you manipulate the temperature in this way in older adults, they will fall asleep 18% faster than typical, and insomnia patients will fall asleep a full 25% faster than usual with this same method. The impact of temperature on sleep is therefore clearly significant, but there is even more to this thermal story, including how you can best wake up from sleep feeling alert, which is what Matt will discuss next episode. Please note that Matt is not a medical doctor, and none of the content in this podcast should be considered medical advice in any way, shape, or form, nor prescriptive in any way.The episode is sponsored by the wonderful folks over at Athletic Greens, who are providing a discount and free product if you use the link above. Athletic Greens is a comprehensive daily nutritional beverage containing 75 vitamins, minerals, and whole food-sourced ingredients, including a multivitamin, multimineral, probiotic.So, head on over to Athletic Greens and get a free year supply of Vitamin D and 5 free travel packs today. Finally, if you have thoughts or feedback you’d like to share, please reach out on Instagram.

23 snips
Jan 3, 2022 • 10min
#12: Melatonin
In today's episode, Matt takes us on a deep dive into melatonin. He covers four main topics: 1) what is melatonin? 2) how does melatonin work? 3) what does melatonin do, and *not* do, for sleep? 4) how can we think about melatonin supplementation?First, Matt describes that melatonin is a naturally occurring hormone released by the brain. He gleefully notes that melatonin is often called, “the vampire hormone” as it comes out at night. In doing so, it signals that it is nighttime, which in turn helps schedule sleep.Second, Matt explains that, during the day, light enters your eyes, and inhibits the release of melatonin. This absence tells your brain that it's daytime and time to be awake. Fast-forward to the evening, and the arrival of darkness, the floodgates of melatonin release open up. We need darkness in the evening to trigger this release, and, in turn, tell your brain that it's nighttime and time to sleep.Matt highlights one significant problem of the present age: we live in a dark-deprived society. Many of us get too much artificial light, and not enough darkness. He shares a tip to dim down half of the lights an hour before bed and avoid screens.Third, Matt elaborates on what melatonin does and does not do; that is, melatonin helps schedule the *timing* of your sleep but does not significantly change the *quality* of sleep. He uses the analogy of a race, where melatonin would be the official who begins the great sleep race but does not participate in the race itself.Finally, Matt discusses supplementation. You can buy melatonin in certain countries to try to use it as a sleep aid. Based on scientific data across the past 15 years, Matt notes that melatonin isn't as effective as you may think: a recent meta-analysis discovered that melatonin only increases the speed with which you fall asleep by 3.9 minutes, and only improves your sleep efficiency by just 2.2%. This reinforces his point that the role of melatonin is primarily in regulating the timing of your sleep, not in sleep generation. Matt states that melatonin is not well regulated as a supplement, and that the strength of melatonin that you buy is often unreliable. He describes a study that examined over 15 different suppliers. Strikingly, when tested, the concentration of melatonin within each pill ranged from 83% less to 478% more than what was stated.Finally, Matt advises that the best way to optimize your sleep is to rely less on melatonin supplementation, and instead, focus on the basics we know make a real difference: sleep regularity, keeping your bedroom cool, getting darkness in the evening, get plenty of natural daylight during the morning, do some physical activity each day, and perhaps most importantly, address your stress and anxiety.Please note that Matt is not a medical doctor, and none of the content in this podcast should be considered medical advice, nor prescriptive in any way.The sponsors of this week's episode are InsideTracker. They are offering 25% off any one of their programs for anyone who uses the above link. InsideTracker is a personalized biometric platform that analyzes your blood and your DNA to better understand what's happening inside of you and also offers suggestions regarding things that you can do to better try and adjust some of those numbers, optimize them, and, as a result, optimize you.So, make your way over to InsideTracker, and take advantage of this incredible deal on this valuable and remarkably convenient service. And, as always, if you have thoughts or feedback you'd like to share, please reach out to Matt on Instagram.

29 snips
Dec 20, 2021 • 10min
#11: Sleep & Caffeine – Part 2
In this week’s episode, Matt continues his discussion of sleep and caffeine. Here, we learn about the paradox of coffee, one in which coffee provides health benefits, despite its negative impact on sleep. Before addressing that, however, Matt speaks about one last sleep consequence of caffeine: regardless of your sensitivity to caffeine, it can still disrupt the quantity and electric quality of your deep non-REM sleep. This can lead to a cycle of caffeine dependency 1) you drink more coffee the next morning to compensate for your poor-quality, unrestorative sleep the night before, which then 2) degrades the quality of your subsequently night's sleep even more, which leads to 3) your potentially reaching for even more sups of coffee the following day, etc, etc.Matt’s advice to still drink coffee (if you want) is due to the many health benefits associated with coffee. How is it possible that coffee has such health benefits, despite the harmful impact of caffeine on sleep? Matt points out that the coffee bean itself contains a sizable blast of antioxidants in every cup. In fact, because of the state of the standard Western diet, coffee is the biggest source of antioxidants for many people in developed nations. However, it is possible to get these benefits without drinking caffeine – many health benefits are similarly associated with drinking decaffeinated coffee since that too contains antioxidants. Therefore, it is the antioxidants in the coffee bean, not the caffeine, that carries the health-related advantages. But Matt is also clear to speak about the fact that when it comes to coffee, the dose, and the timing make the poison. His advice: try to limit it to one to three (at the max) cups in the morning, remembering the quarter-life of caffeine is around 10-12 hours for the average adult. By following these steps, you can maintain a healthy relationship between caffeine, coffee, and this beautiful thing we call sleep at night.Please note that Matt is not a medical doctor, and none of the content in this podcast should be considered medical advice in any way, shape, or form, nor prescriptive in any way.The episode is sponsored by the incredible folks over at Athletic Greens, who are providing a discount and free product if you use the link above. Athletic Greens is a comprehensive daily nutritional beverage containing 75 vitamins, minerals, and whole food-sourced ingredients, including a multivitamin, multimineral, probiotic.So, head on over to Athletic Greens www.athleticgreens.com/mattwalker and get a free year supply of Vitamin D and 5 free travel packs today. Finally, if you have thoughts or feedback you’d like to share, please reach out on Instagram @drmattwalker.

31 snips
Dec 6, 2021 • 11min
#10: Sleep & Caffeine – Part 1
In today's episode, Matt unpacks the world of coffee, and caffeine in the first of a two-part series on caffeine. Matt describes the numerous health benefits associated with coffee, the fact that Matt has even changed his tune a little and advocates a morning cup for some. Matt may not have anything to do with caffeine itself, with more details on that in part 2. In part 1, Matt then takes a deep dive into the different ways in which caffeine negatively impacts your sleep, some of which you may be less familiar with.The first is that caffeine makes it harder for you to fall asleep. Due to activation of the nervous system, caffeine can lead to that unpleasant experience of a racing mind that won't shut off in bed—almost a Rolodex of anxiety that leads to ruminating and therefore catastrophizing.The second impact is that caffeine makes it more difficult for you to stay asleep soundly across the night. This is due, in part, to the fact that caffeine makes your sleep more unstable and fragile, so up more frequently at night. The consequence is something that scientists and doctors call sleep fragmentation, meaning that your overall sleep efficiency, or the consistent quality of your sleep, becomes significantly worse when you have caffeine on board.The third feature that Matt points out centers on caffeine’s duration of action. Caffeine has a half-life of between five to six hours in the average adult. This means that, after five to six hours, 50% of that caffeine is still in your system. What this also means is that caffeine has a quarter-life of approximately 10 to 12 hours for a typical adult. Here, Matt gives us some context: if you have a cup of coffee at 2 PM, a quarter or more of that caffeine could still be circulating in your brain at midnight. Meaning, if you have a cup of coffee at 2 PM, it may be the equivalent of getting into bed at midnight, and just before you turn the lights out, you swig a quarter of a cup of coffee and you hope for a good night of sleep.Matt, however, points out that the 10 to 12 hours quarter-life of caffeine is for the average adult, but this varies significantly from one person to the next. He explains in detail why this is the case: based on differences in genetics, different people will have a more or less efficient version of an enzyme that clears caffeine from their system. Some people will have a version of that enzyme that allows them to remove the caffeine from their system very quickly, whereas other people will have a version of the enzyme that is much slower in its speed of clearing caffeine.Please note that Matt is not a medical doctor, and none of the content in this podcast should be considered medical advice in any way, shape, or form, nor prescriptive in any way.The good people at InsideTracker are the sponsors of this week’s episode, and they are generously offering 25% off any one of their programs for anyone who uses the above link. InsideTracker is essentially a personalized biometric platform that analyzes your blood and your DNA to better understand what's happening inside of you and also offers suggestions regarding things that you can do to better try and adjust some of those numbers, optimize them, and, as a result, optimize you.So, make your way over to InsideTracker, and take advantage of this incredible deal on this valuable and remarkably convenient service. And, as always, if you have thoughts or feedback you’d like to share, please reach out to Matt on Instagram.

18 snips
Nov 22, 2021 • 8min
#09: Sleep & Alcohol - Part 2
On last week’s episode, we learned about the three main ways alcohol can harm our sleep: 1) alcohol results in sedation rather than naturalistic sleep, 2) alcohol causes sleep fragmentation, and 3) alcohol impairs REM sleep. Today, Matt dives into each of these negative impacts, explaining exactly how and why alcohol disrupts our sleep in these specific ways.First, alcohol is a class of chemicals called “the sedatives,” and sedation is not natural sleep. Healthy sleep is a very active, highly coordinated event within the brain, unlike sedation. As a result, alcohol can result in you waking up and feeling unrestored and unrefreshed by that non-normal sleep. Second, we normally need to shut off our fight-or-flight branch of the nervous system, called the sympathetic nervous system, and shift over to the calming, parasympathetic nervous system, in order to stay asleep soundly across the night. However, alcohol reactivates the fight-or-flight nervous system, forcing the brain and body back into a more hyper-alert state. This increases the chances of you waking up and staying awake, causing your sleep to become more fragile and prone to fragmented awakenings throughout the night. Alcohol also triggers the release of several stress-related chemicals, including cortisol. This stimulates the fight-or-flight nervous system and emotional centers in the brain, also making it more likely that you will wake up and stay awake.Finally, alcohol significantly reduces the amount of REM sleep the brain can produce. Specifically, the metabolic byproducts of alcohol degradation within the body disrupts and impairs the generation of REM sleep. Without that REM sleep, we can suffer impairments to our cognitive brain function and emotional stability. We can also experience a heightened amount of negative moods, such as anxiety. REM sleep is also the time when we hit our peak in the release of important hormones, like testosterone, which is critical for both men and women.While Matt acknowledges that this news may not be especially encouraging or popular, he closes out today’s show with a reminder that life is to be lived. It is not his intention to tell anyone how to live their life. Instead, Matt’s goal is to simply lay out the scientific evidence regarding the relationship between sleep and alcohol, so that you can make an informed decision about how to best structure your own sleep schedule and find an enjoyable life balance.Please note that Matt is not a medical doctor and none of the content in this podcast should be considered as medical advice in any way, shape or form, nor prescriptive in any way.The episode is sponsored by the wonderful folks over at Athletic Greens, who are providing a discount and free product if you use the link above. Athletic Greens is a comprehensive daily nutritional beverage containing 75 vitamins, minerals, and whole food-sourced ingredients, including a multivitamin, multimineral, probiotic.So, head on over to Athletic Greens www.athleticgreens.com/mattwalker and get a free year supply of Vitamin D and 5 free travel packs today. Finally, if you have thoughts or feedback you’d like to share, please reach out on Instagram @drmattwalker.

31 snips
Nov 8, 2021 • 11min
#08: Sleep & Alcohol - Part 1
Although some people may believe that a drink or two in the evening will help them sleep better, today’s episode shows us that alcohol harms our sleep in several different ways. In the first of two episodes on sleep and alcohol, Matt talks about alcohol as a chemical, and the main ways it negatively affects our sleep.Alcohol has a sedative effect that switches off brain cell firing as we sleep. Alcohol also fragments our sleep, making it less restorative, and blocks REM sleep, which is critical for numerous aspects of health and wellness, including learning and memory, creativity, rebalancing moods and emotions, recalibrating certain hormone systems, and even lifespan longevity.Matt describes the clock-counter system our brains use to track lost REM sleep, and why we sometimes experience strong, intense and vivid dreams in the late hours of our sleep after too much alcohol as a result. In today’s episode, you’ll also learn about the specific ways in which alcohol interferes with our sleep quality, and the different stages of our sleep, REM sleep especially. Be sure to tune in next week as Matt further examines exactly what it is about alcohol that disrupts our sleep in these particular ways, and what the consequences are on health and wellness.Please note that Matt is not a medical doctor and none of the content in this podcast should be considered as medical advice in any way, shape or form, nor prescriptive in any way.The episode is sponsored by the wonderful folks over at Athletic Greens, who are providing a discount and free product if you use the link above. Athletic Greens is a comprehensive daily nutritional beverage containing 75 vitamins, minerals, and whole food-sourced ingredients, including a multivitamin, multimineral, probiotic.So, head on over to Athletic Greens www.athleticgreens.com/mattwalker and get a free year supply of Vitamin D and 5 free travel packs today. Finally, if you have thoughts or feedback you’d like to share, please reach out on Instagram @drmattwalker.

43 snips
Oct 25, 2021 • 11min
#07: Naps
As the great Roman poet, Ovid, once said, “There is more refreshment and stimulation in a nap, even of the briefest, than all the alcohol ever distilled.” But are naps always a good thing? Are we even designed to nap? And if you do nap, when should you do it, and for how long? Today Matt explores the benefits and pitfalls of napping, how napping may fall in line with our pre-programmed sleep patterns as humans (a natural drop in alertness between 1 and 4pm each day), and what it means if you find yourself waking up from an accidental nap on the couch right before bed. You’ll also hear about the NASA nap culture, sleep inertia (which can include a feeling of a “sleep hangover”), and Matt’s advice for how to use naps to your advantage. If done correctly, for most people not struggling with sleep or insomnia, naps can improve alertness, task performance, creativity, and even reduce blood pressure. However, there is a dark side to napping that Matt discusses in detail, and why that can be the case. So join Matt as he walks you through both the advantages and disadvantages of napping!Please note that Matt is not a medical doctor and none of the content in this podcast should be considered as medical advice in any way, shape or form, nor prescriptive in any way.The episode is sponsored by the wonderful folks over at Athletic Greens, who are providing a discount and free product if you use the link above. Athletic Greens is a comprehensive daily nutritional beverage containing 75 vitamins, minerals, and whole food-sourced ingredients, including a multivitamin, multimineral, probiotic.So, head on over to Athletic Greens www.athleticgreens.com/mattwalker and get a free year supply of Vitamin D and 5 free travel packs today. Finally, if you have thoughts or feedback you’d like to share, please reach out on Instagram @drmattwalker.Detailed Scientific LiteratureNaps and overview (by the amazing Prof. Christopher Barnes)The good and the bad of napsNaps and MortalityNaps, Brain function & Performance

7 snips
Oct 11, 2021 • 7min
#06: Chronotype: Part 3
In the final episode of our three-part series about chronotypes, Matt examines the question of whether your chronotype is truly fixed, or if you can change an evening type to a morning type (though you will hear that Matt’s preference is for society to change, not the individual). Matt reviews a fascinating study by an Australian-lead research team that tried to turn night owls into morning larks. Participants had to follow a series of strict rules over the course of a three-week study. This included things such as: setting an alarm to wake up two to three hours earlier than their normal wake time, eating breakfast first thing after waking up, getting outside for as much natural daylight as possible, and not having any caffeine after 3pm. As you’ll hear from Matt, the experiment was...somewhat successful. By the end of the study, evening types went to bed about two hours earlier than usual, managing to get to be around 12:30am, instead of 2:30am. In addition, their performance on several standardized cognitive tasks also improved expressly during the morning hours, when night owls typically struggle the most. However, as Matt points out, participants were still opting to go to bed after midnight, which is far from morning night-owl-like, and far from being turned into a morning type. It is also unlikely these individuals could continue with this rigid new set of experimental guidelines across the long-term, for their entire lifespans.In other words, the results are fascinating, but the practice itself may not be sustainable in the real world. Instead, Matt's wish is that we simply allow evening types to sleep in harmony with their genetic chronotype. If night owls were able to sleep and wake up when they are biologically designed to, the world would be a happier, healthier place indeed.Please note that Matt is not a medical doctor and none of the content in this podcast should be considered as medical advice in any way, shape, or form, nor prescriptive in any way.The episode is sponsored by the wonderful folks over at Athletic Greens, who are providing a discount and free product if you use the link above. Athletic Greens is a comprehensive daily nutritional beverage containing 75 vitamins, minerals, and whole food-sourced ingredients, including a multivitamin, multimineral, probiotic.So, head on over to Athletic Greens www.athleticgreens.com/mattwalker and get a free year supply of Vitamin D and 5 free travel packs today. Finally, if you have thoughts or feedback you’d like to share, please reach out on Instagram @drmattwalker.Basic Resources Discover your chronotype: AutoMEQ: Automated Morningness-Eveningness Questionnaire (AutoMEQ)Scientific Review: Biological Rhythm and Chronotype