Neurology® Podcast

In the final part of this three-part series, Dr. Stacey Clardy talks with Drs. Elisabeth Bik and Matthew Schrag about the challenges posed by AI in generating fraudulent research, the importance of cultural solutions to uphold scientific integrity, and the need for modernized data management practices in research. Read the related article in Undark.  Disclosures can be found at Neurology.org.

In part two of this special three-part series, Dr. Stacey Clardy talks with Drs. Elisabeth Bik and Matthew Schrag about the processes involved in addressing concerns about research integrity, covering the role of public platforms, using social media for awareness, identifying potential research fraud, and the need for cultural change within the scientific community to prioritize ethical practices. Read the related article in Undark. Disclosures can be found at Neurology.org.

In the first part of this special three-part series, Dr. Stacey Clardy talks with Drs. Elisabeth Bik and Matthew Schrag about critical issues surrounding research integrity and misconduct. Read the related article in Undark. Disclosures can be found at Neurology.org.

Dr. Farrah Mateen talks with Dr. Katrin Seeher about the significant global burden of neurologic conditions, which affects over 3.4 billion people worldwide, and the strategies the WHO is implementing to improve care and awareness. Read the related article in The Lancet Neurology. Disclosures can be found at Neurology.org.  

Dr. Colin Hoy, an expert in prodromal Parkinson's disease, tackles ethical considerations on early diagnosis. Dr. Chris Gibbons sheds light on the innovative use of skin biopsies to detect phosphorylated α-synuclein, showcasing its high sensitivity. Drs. Michiko K. Bruno and Lawrence Golbe discuss practical algorithms for diagnosing atypical parkinsonism, emphasizing the importance of personalized approaches and comprehensive training for healthcare professionals. This conversation navigates the complexities of diagnosis and the promising advancements in neurodegenerative disorder detection.

Dr. Nanditha Rajamani, a researcher specializing in deep brain stimulation, and Dr. Andy Horn, a neurology innovator, dive into the transformative potential of personalized DBS therapy for Parkinson's disease. They discuss cutting-edge advancements, such as tailoring treatments to specific symptom pathways and utilizing modern imaging for precise electrode placement. The conversation highlights the development of the ClearN algorithm to optimize outcomes and emphasizes how data-driven approaches can revolutionize symptom management and enhance patient care.

Dr. Shuvro Roy, a clinician specializing in small-fiber neuropathy management, teams up with Dr. Anne Louise Oaklander, an authority in the field, to discuss vital insights for clinicians. They delve into the diagnostic challenges of relapsing-remitting small fiber neuropathy through a decade-long patient case. The duo also emphasizes the importance of longitudinal studies in improving diagnoses and the creation of a symptom survey to enhance understanding of SFN. Their exploration of treatment complexities during pregnancy adds an intriguing layer to the conversation.

Dr. Dara Albert talks with Dr. Jaclyn M. Martindale about the differences in gender representation among leadership positions and award recipients within the Child Neurology Society. Read the related article in Neurology®. Disclosures can be found at Neurology.org.

Dr. Lawrence Golbe, a prominent figure at Rutgers Robert Wood Johnson Medical School, joins Dr. Jeff Ratliff and Dr. Michiko K. Bruno to discuss a practical diagnostic algorithm aimed at identifying atypical parkinsonian disorders. They explore the significant challenges of diagnosing these disorders due to symptom overlap and the lack of biomarkers. Key topics include the role of MRI in diagnosis, the need for thorough evaluations, and strategies for assessing levodopa responses, all crucial for improving patient care and outcomes.

Dr. Gordon Smith, an expert on critical illness myopathy, joins researchers Dr. Shahar Shelly, who focuses on CMAP duration, and Dr. Teerin Liewluck, who studies myosin loss's impact on mortality. They delve into the vital link between CMAP duration and myosin loss, revealing surprising correlations. The discussion highlights the intricate relationship between muscle weakness, neuropathy, and the challenges in ICU care. Additionally, they emphasize personalized treatment strategies for patients facing these conditions and the importance of accurate diagnosis.