Neurology® Podcast

1) Human herpes 6 virus encephalitis and 2) Topic of the month: Stroke trials. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Joanna Jen interviews Dr. Mina Bhanushali and Sarah Kranick about their paper on human herpes 6 virus encephalitis and stem cell transplantation. Dr. Adam Numis is reading our e-Pearl of the week about ictal syncope. In the next part of the podcast Dr. Brett Kissela interviews Dr. Clay Johnston about CHANCE trial. All the participants have disclosures.Dr. Jen serves as an Associate Editor of Frontiers in Neuro-otology and Section Editor of Experimental Brain Research and receives research support from the FDA.Ms. Kranick is a staff member of the National Institute of Health.Dr. Bhanushali Is an employee of the National Institute of Health.Dr. Numis serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Kissela serves on scientific advisory board for Allergan, Inc.; has received funding for travel and speaker honoraria from Allergan, Inc.; has received research support from the NIH, will receive compensation from Reata Pharmaceuticals, Inc. for serving on the Event Adjudication Committee for the BEACON study, which they are sponsoring. and provides medico-legal reviews.Dr. Johnston serves as Co-Editor-in-Chief of Journal Watch Neurology; serves as Vice Editor of Annals of Neurology; is co-holder of patent on the RNA panel to identify TIA and risk stratify; Stryker Neurovascular, Boston Scientific, Kaiser-Permanente, NCRR/NCATS, CTSA, AHA/ASA, Bugher Award and the NIH and provided expert testimony in legal proceedings for GlaxoSmithKline.

1) PML diagnostic criteria: Consensus statement from AAN Neuroinfectious Disease Section and 2) Topic of the month: Stroke trials. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Andy Southerland interviews Dr. Joseph Berger about the consensus paper from the PML Guidelines Committee of the AAN Neuroinfectious Disease Section. Dr. Andy Numis is reading our e-Pearl of the week about spinal epidural abscesses. In the next part of the podcast Dr. Brett Kissela interviews Dr. Marc Chimowitz about SAMMPRIS trial. The participants had nothing to disclose except Drs. Berger, Numis, Kissela and Chimowitz.Dr. Berger serves as an Associate Editor for the Journal of Neurovirology, serves as an editorial board member of ISRN Education, Neuroscience, World Journal of Rheumatology and MS and other related disorders; serves on the PML adjudication committees of Millenium/Takeda and Amgen; has served as a consultant to Millennium/Takeda, Amgen, Genzyme, Eisai and Novartis; and receives honoraria from Genzyme. Dr. Numis serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Kissela serves on scientific advisory board for Allergan, Inc.; has received funding for travel and speaker honoraria from Allergan, Inc.; has received research support from the NIH, will receive compensation from Reata Pharmaceuticals, Inc. for serving on the Event Adjudication Committee for the BEACON study, which they are sponsoring. and provides medico-legal reviews.Dr. Chimowitz serves as an editorial board member for the journals Stroke and Neurosurgery; has received grant support from NIH/ NINDS to lead multicenter trials on the treatment of intracranial arterial stenosis; for these NIH funded trials, he has also received research support from Stryker Corporation (donation of intracranial stents, payments for 3rd party monitoring of trial), AstraZeneca Corporation (donation of statin), Bayer (donation of aspirin and placebo) and Bristol Myers Squibb (donation of warfarin and placebo); serves on the data safety monitoring board for an industry funded PFO closure study sponsored by Gore Corporation and on a stroke event adjudication panel for an osteoporosis trial funded by Merck and has also provided medico-legal reviews on stroke related cases.

1) NMO spectrum and MS brain lesion and 2) Topic of the month: Stroke trials. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Mark Keegan interviews Dr. Lucy Matthews about her paper on seropositive NMO spectrum disorder and MS brain lesion distribution. Dr. Adam Numis is reading our e-Pearl of the week about intravascular B-cell lymphoma. In the next part of the podcast Dr. Brett Kissela interviews Dr. Joseph Broderick about IMS III trial. All the participants have disclosures.Dr. Keegan serves as Chief Editor for eMedicine; is a consultant for Bionest and Novartis. Dr. Matthews receives research support from UK Medical Research Council and is funded by the Clinical Research Training Fellow ship.Dr. Numis serves on the editorial team for the Neurology® Resident and Fellow Section. Dr. Kissela serves on scientific advisory board for Allergan, Inc.; has received funding for travel and speaker honoraria from Allergan, Inc.; has received research support from the NIH, will receive compensation from Reata Pharmaceuticals, Inc. for serving on the Event Adjudication Committee for the BEACON study, which they are sponsoring. and provides medico-legal reviews.Dr. Broderick has served as a consultant for PhotoThera-DSMB for NEST III study and Genentech, Inc.; receives funding for travel to NIH study section and NIH-sponsored meetings, TST meeting and national meeting by Covidien and RISS Summit by Genentech and as part as invited Visiting Professor; has received research support from Boehringer Ingelheim, Concentric, EKOS, Genentech, Inc, Johnson & Johnson, Novo Nordisk, Schering-Plough Corp, Merck, and the NIH as part of NINDS funded clinical trials.

Encephalopathies caused by drugs, vitamins, infectious and autoimmune disorders

1) Preclinical Alzheimer disease and 2) Topic of the month: Cerebellar ataxias. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Jeff Burns interviews Prof. Michael Ewers about his paper on preclinical Alzheimer disease. Dr. Stacey Clardy is reading our e-Pearl of the week about neurologic symptoms in relapsing polychondritis. In the next part of the podcast Dr. Ted Burns interviews Drs. Susan Perlman and Jeremy Schmahmann about the topic of inherited ataxias and sporadic, degenerative ataxias. In concluding, there is a brief statement where to find other up-to date patient information and current Patient Page. The participants had nothing to disclose except Drs Jeff Burns, Ewers, Clardy, Ted Burns, Perlman and Schmahmann.Dr. Jeff Burns serves on the editorial board for Journal of Alzheimer's Disease; receives royalties for the publications of Early diagnosis and treatment of mild cognitive impairment and Dementia: An atlas of investigation and diagnosis; is a consultant for PRA International and receives research support from the NIH, Alzheimer's Drug Discovery Foundation, Elan, Janssen Pharmaceuticals Inc., Wyeth, Pfizer Inc, Novartis Pharmaceuticals Ltd, Danone, Avid Radiopharmaceuticals, Merck Serono and for clinical trials.Dr. Ewers serves as Senior Editor of Alzheimer's & Dementia and receives compensation for traveling to conferences from the Alzheimer's Association and International College of Geriatric Psychoneuropharmacology.Dr. Clardy served on the editorial team for the Neurology® Resident and Fellow Section. Dr. Ted Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with CSL Behring and Alexion Pharmaceuticals.Dr. Perlman serves on Medical Research Advisory Board for the National Ataxia Foundation, receives research support from Santhera Pharmaceuticals, Edison Pharmaceuticals, Friedreich Ataxia Research Alliance, and ARRAS funding via the RDN-CRC.Dr. Schmahmann serves as an editorial board member for The Cerebellum; receives royalties from the publication of the books The cerebellum and cognition, MRI atlas of the human cerrellum and Fiber pathways of the brain; holds stock options in Brother and for legal counsel to Johnson & Johnson; receives research support from Birmingham Foundation MINDlink Foundation Sidney R. Baer Jr., Foundations and the NIH and has a patent pending for transcranial magnetic stimulation.

1) Niemann-Pick type C and 2) Topic of the month: Cerebellar ataxias. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Ted Burns interviews Dr. Matthis Synofzik about his paper on Niemann-Pick type C. Dr. Stacey Clardy is reading our e-Pearl of the week about cephalic tetanus. In the next part of the podcast Dr. Ted Burns interviews Drs. Susan Perlman and Jeremy Schmahmann about the topic of inherited ataxias. The participants had nothing to disclose except Drs Burns, Synofzik, Clardy, Perlman and Schmahmann.Dr. Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with CSL Behring and Alexion Pharmaceuticals.Dr. Synofzik receives honoraria from Actelion Pharmaceuticals; receives travel funding from Movement Disorders Society and receives research support from the Volkswagen Foundation.Dr. Clardy served on the editorial team for the Neurology® Resident and Fellow Section. Dr. Perlman serves on Medical Research Advisory Board for the National Ataxia Foundation, receives research support from Santhera Pharmaceuticals, Edison Pharmaceuticals, Friedreich Ataxia Research Alliance, and ARRAS funding via the RDN-CRC.Dr. Schmahmann serves as an editorial board member for The Cerebellum; receives royalties from the publication of the books The cerebellum and cognition, MRI atlas of the human cerrellum and Fiber pathways of the brain; holds stock options in Brother and for legal counsel to Johnson & Johnson; receives research support from Birmingham Foundation MINDlink Foundation Sidney R. Baer Jr., Foundations and the NIH and has a patent pending for transcranial magnetic stimulation.

1) Pitfalls in electronic health records and 2) Topic of the month: Cerebellar ataxias. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Mike Brogan interviews Dr. Jim Bernat about his paper on pitfalls in electronic health records. Dr. Stacey Clardy is reading our e-Pearl of the week about Aicardi-Goutieres syndrome. In the next part of the podcast Dr. Ted Burns interviews Drs. Susan Perlman and Jeremy Schmahmann about the topic of other acquired cerebellar ataxias. The participants had nothing to disclose except Drs Bernat, Clardy, Burns, Perlman and Schmahmann.Dr. Bernat serves as an editorial board member of Neurocritical Care, Neurology Today and Multiple Sclerosis and Related Diseases, receives compensation for serving on the editorial board of The Physician's Index for Ethics and Medicine and receives royalties from the publication of the book Ethical issues in Neurology.Dr. Clardy served on the editorial team for the Neurology® Resident and Fellow Section. Dr. Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with CSL Behring and Alexion Pharmaceuticals.Dr. Perlman serves on Medical Research Advisory Board for the National Ataxia Foundation, receives research support from Santhera Pharmaceuticals, Edison Pharmaceuticals, Friedreich Ataxia Research Alliance, and ARRAS funding via the RDN-CRC.Dr. Schmahmann serves as an editorial board member for The Cerebellum; receives royalties from the publication of the books The cerebellum and cognition, MRI atlas of the human cerrellum and Fiber pathways of the brain; holds stock options in Brother and for legal counsel to Johnson & Johnson; receives research support from Birmingham Foundation MINDlink Foundation Sidney R. Baer Jr., Foundations and the NIH and has a patent pending for transcranial magnetic stimulation.

1) Intravenous thrombolysis and 2) Topic of the month: Cerebellar ataxias. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Brett Kissela interviews Dr. Henrik Gensicke about his paper on stroke patients treated with intravenous thrombolysis. Dr. Stacey Clardy is reading our e-Pearl of the week about brachial plexopathy. In the next part of the podcast Dr. Ted Burns interviews Drs. Susan Perlman and Jeremy Schmahmann about the topic of immune-mediated cerebellar ataxias. The participants had nothing to disclose except Drs Kissela, Gensicke, Clardy, Burns, Perlman and Schmahmann.Dr. Kissela serves on scientific advisory board for Allergan, Inc.; has received funding for travel and speaker honoraria from Allergan, Inc.; has received research support from the NIH, will receive compensation from Reata Pharmaceuticals, Inc. for serving on the Event Adjudication Committee for the BEACON study, which they are sponsoring. and provides medico-legal reviews.Dr. Gensicke receives research support from the Swiss National Science Foundation.Dr. Clardy served on the editorial team for the Neurology® Resident and Fellow Section. Dr. Burns serves as Podcast Editor for Neurology®; and has received research support for consulting activities with CSL Behring and Alexion Pharmaceuticals.Dr. Perlman serves on Medical Research Advisory Board for the National Ataxia Foundation, receives research support from Santhera Pharmaceuticals, Edison Pharmaceuticals, Friedreich Ataxia Research Alliance, and ARRAS funding via the RDN-CRC.Dr. Schmahmann serves as an editorial board member for The Cerebellum; receives royalties from the publication of the books The cerebellum and cognition, MRI atlas of the human cerrellum and Fiber pathways of the brain; holds stock options in Brother and for legal counsel to Johnson & Johnson; receives research support from Birmingham Foundation MINDlink Foundation Sidney R. Baer Jr., Foundations and the NIH and has a patent pending for transcranial magnetic stimulation.

Encephalopathies caused by endocrine, electrolyte and organ dysfunction

1) Spinal ischemic stroke and 2) Topic of the month: Child neurology topics. This podcast for the Neurology Journal begins and closes with Dr. Robert Gross, Editor-in-Chief, briefly discussing highlighted articles from the print issue of Neurology. In the second segment Dr. Pearce Korb interviews Dr. Ronen Leker about his paper on spinal ischemic stroke following dialysis. Dr. Chafic Karam is reading our e-Pearl of the week about adrenomyeloneuropathy. In the next part of the podcast Dr. Jeff Waugh interviews Dr. Jonathan Mink about the topic of pediatric movement disorders. In concluding, there is a brief statement where to find other up-to date patient information and current Patient Page. The participants had nothing to disclose except Drs. Leker, Karam and Mink.Dr. Leker serves as an editorial board member of Journal of Molecular Neuroscience, Current Neurovascular Research and Journal of the Israeli Neurological Association.Dr. Karam served on the editorial team for the Neurology® Resident and Fellow Section. Dr. Mink serves as an Associate Editor for Neurology®; serves as an editorial board member of Journal of Child Neurology and Pediatric Neurology; serves on the scientific advisory board for Edison Pharmaceuticals Inc. and Data and Safety Monitoring Board; and receives research support from the NIH.