

This Week in Startups
Jason Calacanis
Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.
Episodes
Mentioned books

May 9, 2023 • 54min
GPT-4 web browsing, plugin demos, AI layoffs + more with Sunny Madra & Vinny Lingham | E1737
Vinny and Sunny join Jason for another AI roundtable to demo ChatGPT’s web browsing capabilities (1:44), discuss AI’s effect on productivity and the workforce (13:53), demo Opus Clip and ChatGPT’s Zillow plugin (33:44), and more!
(0:00) Vinny and Sunny join Jason
(1:44) GPT-4 web browsing demo
(9:10) Inside.com’s AI strategy
(12:22) LinkedIn Marketing - Get a $100 LinkedIn ad credit at https://linkedin.com/thisweekinstartups
(13:53) AI’s effect on productivity and the workforce
(23:36) Hyperice - Get $50 off your order of $150 or more with code TWIST50 at http://hyperice.com/
(25:04) Personal use cases for ChatGPT
(30:56) Market Pull
(33:44) Opus Clip demo
(39:55) Trovata - Use code TWIST at https://trovata.io/twist for 30% off one year of premium features, like AI forecasting
(41:08) Synthesia
(43:11) Zillow plugin demo
(49:51) The future of ChatGPT Plugins
FOLLOW Sunny: https://twitter.com/sundeep
FOLLOW Vinny: https://twitter.com/vinnylingham
FOLLOW Jason: https://linktr.ee/calacanis
Subscribe to our YouTube to watch all full episodes:
https://www.youtube.com/channel/UCkkhmBWfS7pILYIk0izkc3A?sub_confirmation=1
FOUNDERS! Subscribe to the Founder University podcast:
https://podcasts.apple.com/au/podcast/founder-university/id1648407190

May 5, 2023 • 46min
Mining asteroids with AstroForge CEO Matthew Gialich | E1736
AstroForge CEO Matthew Gialich joins Jason to discuss his startup’s lofty goal of mining Platinum Group Metals from asteroids (1:11). They discuss the recent launch of their Brokkr-1 space vehicle, the company’s road map to gather PGMs successfully from space, and SpaceX’s impact on the space industry (5:42). Then, Founder University’s Kelly Schricker gives a presentation on how to set up a fundraising process for your startup (31:51).
(0:00) AstroForge’s Matthew Gialich joins Jason
(1:11) The purpose of mining asteroids
(5:42) Brokkr-1 mission
(10:38) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://Squarespace.com/TWIST
(12:09) AstroForge’s roadmap
(16:07) Unit economics of hardware-based businesses
(17:38) Scaling Virgin Orbit and Virgin Galactic
(20:51) Pilot - Get 20% off the first 6 months at https://pilot.com/twist
(22:20) The evolution of the space economy
(30:43) Crowdbotics - Get a free scoping session for your next big app idea at http://crowdbotics.com/twist
(31:51) How to set up a fundraising process
FOLLOW Matt: https://twitter.com/MattGialich
FOLLOW Kelly: https://twitter.com/KSchricks
FOLLOW Jason: https://linktr.ee/calacanis
Subscribe to our YouTube to watch all full episodes:
https://www.youtube.com/channel/UCkkhmBWfS7pILYIk0izkc3A?sub_confirmation=1
FOUNDERS! Subscribe to the Founder University podcast:
https://podcasts.apple.com/au/podcast/founder-university/id1648407190

May 4, 2023 • 1h 9min
Airbnb CEO Brian Chesky on early rejection, customer focus & AI’s future in hospitality | E1735
Airbnb CEO and Co-Founder Brian Chesky joins Jason to tell the story of Airbnb’s early startup struggles (1:29) and discuss how the company has restructured operations to heighten focus on the product and its customers (16:05). They dive into addressing customer complaints, hyper-focused marketing, the AI opportunity for Airbnb, and much more (40:26).
(0:00) Airbnb’s Brain Chesky joins Jason
(1:29) Brian’s experience with early rejection
(14:48) Lemon.io - Get 15% off your first 4 weeks of developer time at https://Lemon.io/twist
(16:05) Airbnb’s company structure and focusing on product first
(25:26) Miro - Sign up for a free account at https://miro.com/startups
(26:42) Staying focused, getting permission from your customers, and Airbnb’s new updates
(38:53) Embroker - Use code TWIST to get an extra 10% off insurance at https://Embroker.com/twist
(40:26) Addressing customer complaints and Brian’s philosophy on remote work
(49:23) AI’s future in hospitality and Brian’s personal experience with ChatGPT
FOLLOW Brian: https://twitter.com/bchesky
FOLLOW Jason: https://linktr.ee/calacanis
Subscribe to our YouTube to watch all full episodes:
https://www.youtube.com/channel/UCkkhmBWfS7pILYIk0izkc3A?sub_confirmation=1
FOUNDERS! Subscribe to the Founder University podcast:
https://podcasts.apple.com/au/podcast/founder-university/id1648407190

May 3, 2023 • 51min
Uber earnings + using AI to revolutionize clinical trials w/ Unlearn.AI’s Charles Fisher | E1734
First up, Jason breaks down Uber’s huge Q1 results! (1:21) Then, Unlearn.AI CEO Charles Fisher joins to discuss the advancements his company is making in fast-tracking clinical trials (9:49), how machine learning is used in drug development (16:24), Unlearn’s business model (35:24), and more!
(0:00) Jason kicks off the show
(1:21) Uber’s Q1 earnings
(8:31) QuickNode - Get one month free by using code TWIST at https://go.quicknode.com/twist
(9:49) The foundation of Unlearn.AI
(12:42) Unlearn.AI’s impact on the clinical trial process
(14:24) Criticisms of the current clinical trial model
(16:24) ML’s Impact on drug discovery
(24:16) CacheFly - Get 10 terabytes free by signing up at https://twist.cachefly.com
(25:42) The data used in the medical system today
(34:05) Microsoft for Startups Founders Hub - Apply in 5 minutes for six figures in discounts at http://aka.ms/thisweekinstartups
(35:24) Unlearn.AI’s business model
(40:22) Building a foundational model for health
(44:06) The pace of AI today vs. the previous decade
(46:35) More on Unlearn.AI’s business model
(48:15) Creating foundational datasets in health
FOLLOW Charles: https://twitter.com/charleskfisher
FOLLOW Jason: https://linktr.ee/calacanis
Subscribe to our YouTube to watch all full episodes:
https://www.youtube.com/channel/UCkkhmBWfS7pILYIk0izkc3A?sub_confirmation=1
FOUNDERS! Subscribe to the Founder University podcast:
https://podcasts.apple.com/au/podcast/founder-university/id1648407190

May 2, 2023 • 1h
BuzzFeed vs Gawker, AI’s impact on the future of media, and more with Semafor’s Ben Smith | E1733
Jason is joined by Semafor Co-Founder and EIC Ben Smith to dive into his new book and explore the current state of media. They break down BuzzFeed vs Gawker, why media unions might not work (29:35), the future of journalism (36:54), and much more!
(0:00) Jason kicks off the show
(1:55) Semafor's Ben Smith joins Jason
(4:27) Ben's career in media
(6:19) The previous era of publishing
(9:13) The significance of BuzzFeed and Gawker
(13:49) LinkedIn Jobs - Post your first job for free at https://linkedin.com/twist
(14:53) Gawker's ethos
(19:31) The bet on companies like Facebook for media
(23:25) BuzzFeed's future
(24:51) Vanta - Get $1000 off your SOC 2 at https://vanta.com/twist
(26:07) Vice and Vox
(29:35) Unions in media
(35:34) iConnections - Get 20% off iConnections Miami 2024 event at https://iConnections.io/twist
(36:54) The clash between journalism and business
(45:34) Broadcast TV and going direct
(46:19) What is happening with Fox and CNN
(52:48) SBF and Semafor
FOLLOW Ben: https://twitter.com/semaforben
FOLLOW Jason: https://linktr.ee/calacanis
Subscribe to our YouTube to watch all full episodes:
https://www.youtube.com/channel/UCkkhmBWfS7pILYIk0izkc3A?sub_confirmation=1
FOUNDERS! Subscribe to the Founder University podcast:
https://podcasts.apple.com/au/podcast/founder-university/id1648407190

May 1, 2023 • 1h 12min
Demoing the most innovative new ChatGPT features with Sunny Madra and Vinny Lingham | E1732
Sunny and Vinny are back to break down ChatGPT's latest innovation: the Code Interpreter. They demonstrate its capabilities with two separate datasets on EVs in America and US Bank Failures (10:58) before discussing how platforms like ChatGPT will revolutionize organizational efficiency (31:19).
(0:00) Jason kicks off the show
(2:06) ChatGPT's new code interpreter
(9:24) OpenPhone - Start your free trial and get 20% off at https://openphone.com/twist
(10:58) ChatGPT's Code Interpreter example with EV data
(23:50) Coda - Get a $1,000 startup credit at https://coda.io/twist
(25:13) The global GPU shortage
(28:10) ChatGPT's Code Interpreter example with US Bank Failures
(31:19) How ChatGPT will change the modern-day organization
(38:55) Release - Get your first month free at https://release.com/twist
(40:27) Getting more efficient with ChatGPTs new updates
(47:53) Web browsing with ChatGPT
(56:11) How this technology will enable people
(1:04:15) How this has impacted Sunny
FOLLOW Sunny: https://twitter.com/sundeep
FOLLOW Vinny: https://twitter.com/vinnylingham
FOLLOW Jason: https://linktr.ee/calacanis
Subscribe to our YouTube to watch all full episodes:
https://www.youtube.com/channel/UCkkhmBWfS7pILYIk0izkc3A?sub_confirmation=1
FOUNDERS! Subscribe to the Founder University podcast:
https://podcasts.apple.com/au/podcast/founder-university/id1648407190
OTHER LINKS:
https://twitter.com/jbrowder1/status/1652387444904583169?s=20

Apr 28, 2023 • 1h 16min
Big Tech earnings breakdown w/TechCrunch's Alex Wilhelm | E1731
TechCrunch's Alex Wilhelm joins Jason to break down the big tech's Q1 earning reports (0:53). They discuss Google's culture of entitlement, Microsoft's AI momentum, Meta's year of efficiency, how Amazon may be in for a few quarters of pain, and Snap's double-digit drop (21:11).
(0:00) Nick kicks off the show
(0:53) TechCrunch's Alex Wilhelm joins Jason
(1:23) Reflecting on SVB contagion
(3:48) First Republic Bank and BuzzFeed's stock
(6:16) Uber's profits
(8:23) Embroker - Use code TWIST to get an extra 10% off insurance at https://Embroker.com/twist
(9:56) The SF boom/bust
(14:52) More on BuzzFeed
(19:41) Miro - Sign up for a free account at https://miro.com/startups
(21:11) Google's earnings
(25:28) Google's culture of entitlement
(31:40) Integrating ChatGPT into your workflow
(35:47) AI innovation in hospitality
(38:12) Crowdbotics - Get a free scoping session for your next big app idea at http://crowdbotics.com/twist
(39:23) Microsoft's earnings
(43:19) Meta earnings
(54:29) Amazon's earnings
(1:04:08) Snap's earnings
(1:11:34) Thoughts on TikTok
FOLLOW Alex: https://twitter.com/alex
FOLLOW Jason: https://linktr.ee/calacanis
Subscribe to our YouTube to watch all full episodes:
https://www.youtube.com/channel/UCkkhmBWfS7pILYIk0izkc3A?sub_confirmation=1
FOUNDERS! Subscribe to the Founder University podcast:
https://podcasts.apple.com/au/podcast/founder-university/id1648407190

Apr 27, 2023 • 1h 4min
Billy McFarland on Fyre Fest fraud, failure, hacking, & the long road back | E1730
Billy McFarland joins Jason to discuss the lessons he has learned from his Fyre Fest fraud, before discussing the festival’s origin story and what led him to winding up in jail (1:36). This leads to an all-encompassing conversation about Billy’s early days as an entrepreneur, his experience in prison, and if he is a changed man (13:46).
(0:00) Jason kicks off the show
(1:36) Reflecting on Fyre Festival
(6:57) The origin of Billy’s charisma & communication
(11:31) Billy’s first experience with computers
(12:29) Vanta - Get $1000 off your SOC 2 at https://vanta.com/twist
(13:46) Spling
(14:40) Billy’s experience in solitary confinement
(17:52) The origins of Fyre Festival
(25:34) Pilot - Get 20% off the first 6 months at https://pilot.com/twist
(27:06) Billy’s behavioral changes
(29:02) Fyre Festival ticket sales
(30:41) Fyre’s board of directors
(36:22) DIY Syndrom
(39:28) Hyperice - Get $50 off your order of $150 or more with code TWIST50 at http://hyperice.com/
(40:57) Billy’s early release from prison
(43:37) Billy’s prison experience
(46:22) The final moments before Fyre Festival
(50:44) Can we trust Billy Macfarland 2.0?
FOLLOW Billy: https://twitter.com/pyrtbilly
FOLLOW Jason: https://linktr.ee/calacanis
Subscribe to our YouTube to watch all full episodes:
https://www.youtube.com/channel/UCkkhmBWfS7pILYIk0izkc3A?sub_confirmation=1
FOUNDERS! Subscribe to the Founder University podcast:
https://podcasts.apple.com/au/podcast/founder-university/id1648407190

Apr 26, 2023 • 1h 14min
AI’s Future: Opportunity, Regulation & Limits with Vinny Lingham & Sunny Madra | E1729
Vinny and Sunny join Jason to discuss the three phases of AI adoption and the emergence of new business models (1:55), which leads to a conversation about Grimes open-sourcing her AI-generated vocals before debating whether the government should regulate AI (24:57). They wrap with a conversation about AI’s technical constraints, OpenAI’s transparency issues, and the future of startups (39:31).
(0:00) Show start
(1:04) Vinny and Sunny join Jason
(1:55) The three phases of AI adoption
(11:15) CacheFly - Get 10 terabytes free by signing up at https://twist.cachefly.com
(12:41) Building AI applications
(18:27) House of Macadamias - Get 20% off your first purchase and a free bottle of cold-pressed macadamia oil at http://houseofmacadamias.com/twist by using code twist20
(19:59) Emerging business models
(24:57) Grimes’ approach to AI-generated music
(28:31) Notion - Take the first step toward an organized, happier team. Apply for Notion for Startups at https://notion.com/jason.
(30:04) Regulating AI
(39:31) The technical constraints of AI
(45:33) Becoming more efficient with AI
(51:16) OpenAI’s lack of transparency
(1:01:44) Lessons from Mahalo
(1:05:55) The future of startups
(1:08:36) Reflecting on the Starship launch
FOLLOW Sunny: https://twitter.com/sundeep
FOLLOW Vinny: https://twitter.com/vinnylingham
FOLLOW Jason: https://linktr.ee/calacanis
Subscribe to our YouTube to watch all full episodes:
https://www.youtube.com/channel/UCkkhmBWfS7pILYIk0izkc3A?sub_confirmation=1
FOUNDERS! Subscribe to the Founder University podcast:
https://podcasts.apple.com/au/podcast/founder-university/id1648407190

Apr 25, 2023 • 55min
Spotify earnings, Grimes takes AI-based music approach + Cafe X CEO Henry Hu | E1728
Jason starts the show by breaking down Spotify’s latest earnings report before discussing pop star Grimes taking to Twitter to announce a new business model for her AI-generated music (1:44). Then, Cafe X CEO Henry Hu joins Jason to discuss their latest equity crowdfund and being resilient, surviving a downturn, and more (18:22).
(0:00) Jason kicks off the show
(1:44) Spotify Earnings
(8:25) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://Squarespace.com/TWIST
(9:56) Grimes takes an AI-based music approach
(16:57) LinkedIn Marketing - Get a $100 LinkedIn ad credit at https://linkedin.com/thisweekinstartups
(18:22) What is Cafe X?
(26:20) Advantages of a robot arm
(31:10) Brilliant.org - Get 20% off an annual subscription at http://brilliant.org/twist
(32:40) Cafe X’s pivot
(38:07) Pricing of the Cafe X system
(40:54) Cafe X’s OS
(42:42) Raising equity crowdfunding
(43:11) Navigating edge issues
(45:22) Finding success and Cafe X’s current focus
(50:38) Inventing menu items and other use cases
FOLLOW Henry: https://twitter.com/supergeek18
FOLLOW Jason: https://linktr.ee/calacanis
Subscribe to our YouTube to watch all full episodes:
https://www.youtube.com/channel/UCkkhmBWfS7pILYIk0izkc3A?sub_confirmation=1
FOUNDERS! Subscribe to the Founder University podcast:
https://podcasts.apple.com/au/podcast/founder-university/id1648407190


