Dr. Christopher Hobbs is a world-renowned author, clinician, botanist, mycologist, and research scientist, with over 35 years of experience with herbal medicine. He is the author of the classic, "Medicinal Mushrooms: The Essential Guide." In this second half of a two-part episode, Dr. Hobbs and Dr. Plotkin look at the history of medicinal herbs and fungi, discuss the benefits and questions surrounding microdosing, and ponder their healing potential in the context of modern times.

Dr. Christopher Hobbs is a world-renowned author, clinician, botanist, mycologist, and research scientist, with over 35 years of experience with herbal medicine. He is the author of the classic, "Medicinal Mushrooms: The Essential Guide." In this first half of a two-part episode, Dr. Hobbs and Dr. Plotkin look at the history of medicinal herbs and fungi, discuss how to find the best products, and  discuss their healing potential in the context of modern times.

Hamilton Morris is an American journalist, filmmaker and scientific researcher. Previously a writer for Vice magazine with a monthly column “Hamilton’s Pharmacopeia”, Morris currently conducts pharmacological research at St. Joseph’s University in Philadelphia. Interested in psychoactive substances and hallucinogens, Morris’ interests overlap with those of ethnobotanist Dr. Mark Plotkin. In this second half of a two-part episode, Morris and Dr. Plotkin ponders synthetic versus organic psychedelics, microdosing and the magic of hallucinogens.

Hamilton Morris is an American journalist, filmmaker and scientific researcher. Previously a writer for Vice magazine with a monthly column “Hamilton’s Pharmacopeia”, Morris currently conducts pharmacological research at St. Joseph’s University in Philadelphia. Interested in psychoactive substances and hallucinogens, Morris’ interests overlap with those of ethnobotanist Dr. Mark Plotkin. In this first half of a two-part episode, Morris and Dr. Plotkin ponder magic frogs, Iboga and the magic of hallucinogens.

Paul Stamets is a leading American mycologist, author of many books and best known for his role in the award-winning documentary and accompanying book "Fantastic Fungi". An advocate of medicinal fungi, Stamets' interests overlap with those of ethnobotanist Dr. Mark Plotkin. In this episode, Stamets and Dr. Plotkin continue their discussion pondering mushrooms, magic and mortality, while challenging some Western beliefs with personal observations, experiences and ideas.   Recorded by award-winning nature photographer Joshua Bloom (realityinbloom.com) at the ESPD55 – Ethnopharmacologic Search for Psychoactive Drugs – Conference (espd55.com). Special thanks to Joshua Bloom, Dylan Fitchett, Dennis McKenna, and the McKenna Academy of Natural Philosophy.

Paul Stamets is a leading American mycologist, author of many books, and best known for his role in the award-winning documentary and accompanying book, Fantastic Fungi. An advocate of medicinal fungi, Stamets' interests overlap with those of ethnobotanist Dr. Mark Plotkin. In this episode, Stamets and Dr. Plotkin ponder mushrooms, magic, and mortality, challenging some Western beliefs with personal observations, experiences, and ideas.   Recorded by award-winning nature photographer Joshua Bloom (realityinbloom.com) at the ESPD55 – Ethnopharmacologic Search for Psychoactive Drugs – Conference (espd55.com). Special thanks to Joshua Bloom, Dylan Fitchett, Dennis McKenna, and the McKenna Academy of Natural Philosophy.

In the previous episode, we learned how and why Absinthe was considered the ultimate creative elixir in 19th century Belle Epoque France. However, absinthe also served as an inspiration for artists in New Orleans, long regarded as the most European city in the US. As we heard in previous episodes on opium (S1E6) and cannabis (S2E7), New Orleans has long been awash in mind-altering plant products, all of which have played a vital role in the city's fecund creativity which gave rise to jazz, rhythm and blues, and rock and roll. 

Wormwood - the basis of absinthe - has been valued medicinally since ancient times. However, the development of absinthe several hundred years ago created a drink which turbocharged the creativity of geniuses as diverse as Toulouse Lautrec, Oscar Wilde, Ernest Hemingway and Pablo Picasso. This episode details that story.   Sources: Adams, Jennifer, et al. Philip Collier's Mixing New Orleans: Cocktails and Legends. Philbeau, 2007.   Baker, Phil. The Book of Absinthe. Grove Press. 2001.  Conrad, Barnaby. Absinthe: History in a Bottle. Chronicle Books, 1997.   Crowley, Aleister. Absinthe, the Green Goddess. Contra/Thought, 1995.   Hemingway, Ernest. For Whom the Bell Tolls. Scribner, 2020.   Hepworth, David. Uncommon People: The Rise and Fall of the Rock Stars. Black Swann, 2018.   Mann, J. Turn on and Tune in: Psychedelics, Narcotics and Euphoriants. Royal Society of Chemistry, 2019.   Wittels, Betina J., and T. A. Breaux. Absinthe: The Exquisite Elixir. Fulcrum Publishing, 2017.   Wondrich, David, and Noah Rothbaum. The Oxford Companion to Spirits and Cocktails. Oxford University Press, 2022.  

Today, we'll follow Dr. Mark Plotkin as he shares the story of Richard Evans Schultes, who, as a busy work-study undergraduate student at Harvard, chose the shortest book he could find to serve as the subject of his term paper for his Plants & Human Affairs class. As fate would have it, this short book – which happened to be about peyote – would launch his career. Not only would he go on to teach this very same class years later, he has come to be revered as the father of ethnobotany.

Peyote is a tiny cactus that has had a giant impact on history and culture. It is one of the most ancient hallucinogens - finds near the Texas-Mexico border indicate that humans have been consuming this Plant of the Gods for over 6000 years. Many credit Aldous Huxley's 1954's book "The Doors of Perception" - based on his experiences with mescaline, the most active alkaloid in peyote - as launching the Psychedelic Renaissance. And this cactus and this alkaloid and this book impacted The Beatles, The Doors and The Who as well. This episode tells that story.