Podcast Notes Playlist: Latest Episodes

A16z Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- What if now is the best time in decades to start a company?In this episode, taken from Speedrun, a16z’s accelerator for early-stage founders, Marc Andreessen joins games General Partner Jonathan Lai to make the case that we’re entering a once-in-a-generation window for innovation. From the rise of AI to the cultural and policy shifts reshaping the global economy, Marc explains why the next four years present a rare opportunity for builders to seize the moment.Along the way, they discuss market timing, platform shifts, and what sets successful founders apart - including lessons from Steve Jobs, insights into AI’s impact on storytelling and games, and why being “too early” can feel just like being wrong.Timecodes0:00 Lessons from Steve Jobs on Leadership & Innovation2:27 The AI Boom: How It’s Changing Everything5:52 Market Timing: The #1 Factor in Startup Success8:13 Why the Next 4 Years Are Critical for Tech11:30 AI & The Future of Gaming, Storytelling & Virtual Worlds14:28  Why Some Startups Fail While Others Explode17:11  The Role of Founders in the AI EraResources: Find Marc on X: https://x.com/pmarcaFind Jonathan on X: https://x.com/TocelotStay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Twenty Minute VC: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Philipp Freise is Co-Head of European Private Equity at KKR, where he manages the largest private fund in Europe with $8BN in the latest fund. Philip has led KKR's investments in FGS Global, Superstruct, Axel Springer SE, BMG Rights Management, Fotolia, GetYourGuide, GfK SE, Leonine, Mediawan SAS, Scout24 Switzerland and Trainline. Previously, Philip worked at McKinsey & Company in and co-founded Berlin-based VC firm Venturepark, Europe's first pan-European incubator. Agenda: 00:00 – "We Lost $500M in Turkey. Here’s Why We’ll Never Do It Again." 01:40 – Inside Europe’s Biggest PE Fund: $8B of Pure Firepower 03:55 – The $100M Dot-Com Failure That Changed My Career 06:45 – Why Picking the Wrong VC Will Destroy Your Company 10:20 – KKR’s $500M COVID Gamble: Genius or Insane? 12:35 – Why We Ignored the Market & Deployed 40% of Our Fund 15:55 – KKR’s Ruthless Portfolio Discipline: Love Doesn’t Matter 17:10 – Do Power Laws Apply in PE? Freise Destroys the Myth 18:45 – The Truth About Capital Intensity in the Age of AI 20:10 – Can AI Kill the PE Model? Here’s What Philipp Says 26:00 – The Secret to Great Investment Decisions at KKR 32:40 – Why There’s a $3T Liquidity Time Bomb in Venture 34:25 – The Death of IPOs? How KKR Exits Without Going Public 40:05 – Will KKR Europe Hit $20B? Freise's Bold Prediction 43:45 – Helsing, Space, and Defense: The New Age of DeepTech Bets 45:30 – Tariffs, China, and the Future of the German Car Empire 47:00 – Freise vs. Bitcoin: Will USD Still Rule in 10 Years? 48:15 – 4 Global Shocks Happening Right Now That You Need to Know 51:30 – KKR Missed Spotify AND Alibaba?! The Painful Stories 53:00 – Do Andreessen & General Catalyst Scare KKR? Freise Responds 54:30 – The One Metric That Will Define KKR’s Next Decade  

Mark Manson, a New York Times best-selling author and entrepreneur, shares insightful lessons on life and relationships. He discusses the impact of toxic individuals and the importance of setting boundaries for mental health. Mark also explores the difference between true love and obsession, advocating for authentic connections. He emphasizes personal responsibility and the value of confronting uncomfortable truths for growth, while highlighting the significance of self-acceptance in dating and the dangers of societal expectations.

In this engaging discussion, Dr. Daniel Amen shares his vast expertise as a psychiatrist and brain-health researcher. He unveils the 11 risk factors harming our brains and the crucial influence of childhood experiences on mental health. Delving into the food-brain connection, he highlights how diet affects cognitive function and offers strategies to combat brain fog. Furthermore, Dr. Amen discusses the impacts of chronic stress, societal pressures, and the importance of self-reflection for maintaining mental wellness.

The Great Simplification with Nate Hagens ✓ Claim : Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Economics departments around the world teach a narrow boundary story of the way our world works. A narrative of infinite growth driven by consumption and money, which has dominated our culture and unknowingly shaped the way we live. But does this story really reflect our biophysical reality – or the full scope of humanity’s role within it? In this week’s Frankly, Nate identifies 10 myths being taught in business schools today, and the massive implications these misconceptions hold for society. From the way we define value and the boundaries of success to the idolization of self-interest and human ingenuity, these so-called laws of economics were developed in a different world than the one we inhabit now. By exposing the unquestioned myths that are perpetuated in MBA education, Nate aims to sow the seeds of an economic system rooted in the real world – which may one day become a reality. What would it take for the long-held “immutable truths” of economic theory to be questioned, and eventually changed to better reflect our material limits?  How do we redefine "success" in a way that does not posit GDP as the main indicator of human or economic well being? Most importantly, if we shed ourselves of these delusions, how might we reimagine an economic system that centers the well-being of citizens, the health of the planet, and all of the species we share it with? (Recorded June 9, 2025)     Show Notes and More Watch this video episode on YouTube   Want to learn the broad overview of The Great Simplification in 30 minutes? Watch our Animated Movie.   ---   Support The Institute for the Study of Energy and Our Future   Join our Substack newsletter   Join our Discord channel and connect with other listeners  

James Altucher Show: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Notes from James:When I turned 40, I was depressed. I checked the top 50 chess players and saw only one person around my age: Viswanathan Anand. That moment gave me hope.Episode Description:I met one of my lifelong heroes—five-time World Chess Champion Viswanathan Anand—and got to sit down with him at the Norway Summit to unpack what it really takes to stay at the top… for four decades. We didn’t just talk about chess—we talked about life, legacy, improvement, and how to overcome self-doubt at any age.Vishy and I broke down how talent evolves, why confidence matters more than skill early on, and how he battled through plateaus, age, and even failure to remain among the world’s elite players—well into his 50s. This episode is a masterclass in longevity, performance, and reinvention.Whether you're into chess or not, Vishy's insights apply to anyone striving to master their craft, overcome obstacles, and stay in the game.What You’ll Learn:The real reason most people plateau—and how to push through itWhy youth is powered by “inaccurate self-confidence” (and why that’s not a bad thing)How to adapt when the game—or the world—changes faster than you can keep upWhat to do when your best effort still leads to lossHow to retrain your mindset after failure or self-doubtWhy reinvention is a lifelong skill, not a one-time fixTimestamps:00:00 The Relentless Nature of Chess00:39 Meeting My Hero: Viswanathan Anand01:12 A Personal Story of Inspiration02:55 Interview with Viswanathan Anand06:43 The Evolution of Chess and Personal Growth28:57 The Role of Youth and Confidence in Chess31:14 Concluding Thoughts and Future ProspectsSponsors:Visit “LandRoverUSA.com” to learn more about the Defender one-tenTo get 6 bottles of wine for $39.99, head to NakedWines.com/JAMES and use code JAMES for both the CODE AND PASSWORD.Elevate your workspace with UPLIFT Desk. Go to https://upliftdesk.com/james for a special offer exclusive to our audience.Visit northwestregisteredagent.com/james and start building something amazing! Get more with Northwest Registered Agent at northwestregisteredagent.com/james.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

A16z Podcast: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- What if the rise of Apple also built modern China?a16z’s Erik Torenberg is joined by board partner and former Microsoft Windows chief Steven Sinofsky to unpack how Apple’s pursuit of design excellence and supply chain scale catalyzed China’s manufacturing superpower status - and why that partnership is now under intense scrutiny.Inspired by the book Apple in China (but not a book review), the episode dives deep into:The early days of Apple’s shift to Chinese manufacturing What experts got wrong in 1999 about trade, globalization, and China’s trajectoryHow Tim Cook’s operational playbook reshaped the global tech industryBehind-the-scenes stories from Microsoft’s own hardware battles and Surface launchWhy Apple’s entanglement with China may now be a strategic liabilityWhat COVID revealed about fragile global dependencies — and where innovation goes nextHow national policy, intellectual property, and AI intersect in the new industrial eraThe episode opens with a few reactions to WWDC: Apple’s new UI, the iPad’s evolving role, and why Apple’s AI story still feels unfinished - before zooming out into one of the most consequential tech and geopolitical stories of our time.TImecodes:00:00 Introduction00:37 Guest Introduction: Steven Sinofsky00:49 WWDC Reactions and Apple's AI Story02:27 WWDC Highlights: Liquid Glass and iPad Updates05:16 Apple's AI Strategy and Market Dynamics06:34 Meta's AI Moves and Market Implications13:30 Apple's Manufacturing Evolution: From Garage to Global20:50 The Rise of ODMs and Global Manufacturing26:32 Microsoft's Struggle with Piracy in China27:19 Apple's Revolutionary MacBook Air29:30 Challenges in PC Manufacturing31:05 The Rise of Chinese Manufacturing Skills32:07 The Point of No Return for Apple and China32:59 Global Trade and Intellectual Property Issues37:04 COVID-19's Impact on Global Manufacturing41:19 Future of Innovation and Manufacturing47:10 Navigating Intellectual Property in the AI Era48:55 Conclusion and Final ThoughtsResources:Find Steven on X: https://x.com/stevesiFind Erik on X: https://x.com/eriktorenbergStay Updated: Let us know what you think: https://ratethispodcast.com/a16zFind a16z on Twitter: https://twitter.com/a16zFind a16z on LinkedIn: https://www.linkedin.com/company/a16zSubscribe on your favorite podcast app: https://a16z.simplecast.com/Follow our host: https://x.com/eriktorenbergPlease note that the content here is for informational purposes only; should NOT be taken as legal, business, tax, or investment advice or be used to evaluate any investment or security; and is not directed at any investors or potential investors in any a16z fund. a16z and its affiliates may maintain investments in the companies discussed. For more details please see a16z.com/disclosures.

Shawn Ryan Show: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Augustus Doricko is the founder and CEO of Rainmaker, a next generation cloud seeding company. He is a UC Berkeley dropout, Thiel Fellow, and member of the El Segundo hard tech scene.  Rainmaker uses weather resistant drones to increase precipitation and novel radar hardware to measure how much man-made precipitation is created. Rainmaker’s first priority is reversing the desertification of the American west, and ultimately to terraform deserts into abundant, green, arable land. Shawn Ryan Show Sponsors: https://www.roka.com - USE CODE SRS https://www.americanfinancing.net/srs NMLS 182334, nmlsconsumeraccess.org https://www.tryarmra.com/srs https://www.betterhelp.com/srs This episode is sponsored by better help. Give online therapy a try at betterhelp.com/srs and get on your way to being your best self. https://www.shawnlikesgold.com https://www.lumen.me/srs https://www.patriotmobile.com/srs https://www.rocketmoney.com/srs https://www.shopify.com/srs https://trueclassic.com/srs Upgrade your wardrobe and save on @trueclassic at trueclassic.com/srs! #trueclassicpod Augustus Doricko Links: Rainmaker - https://www.rainmaker.com X - https://x.com/ADoricko  LinkedIn - https://www.linkedin.com/in/augustus-doricko-660b20145 Substack - https://substack.com/@doricko Learn more about your ad choices. Visit podcastchoices.com/adchoices

The Tucker Carlson Show: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- Doctors told a teenage Laura Delano she had something they called bipolar disorder, and then proceeded to make her legitimately crazy with psych drugs. She’s one of the few who recovered. (00:00) Introduction (01:20) Why Is the New York Times Mad at Delano for Getting off Antidepressants? (15:32) The Major Problem With Psychiatry Diagnoses (34:43) How Many Americans Are on Psychiatric Drugs? (55:00) The Drugs That Kill Your Life-Force Paid partnerships with: ExpressVPN: Go to https://ExpressVPN.com/Tucker and find out how you can get 4 months of ExpressVPN free! PureTalk: Go to https://PureTalk.com/Tucker to make the switch Policygenius: Head to at https://Policygenius.com/Tucker to see how much you could save Laura Delano is an author, speaker, and consultant, and the founder of Inner Compass Initiative, a nonprofit organization that helps people make more informed choices about taking and safely tapering off psychiatric drugs. She is a leading voice in the international movement of people who’ve left behind the medicalized, professionalized mental health industry to build something different. Laura has worked as an advocate within and beyond the mental health system, and has spent the past 13 years working with individuals and families around the world who are seeking guidance and support for psychiatric drug withdrawal. Her book, Unshrunk: A Story of Psychiatric Treatment Resistance, was published in March 2025.   Unshrunk: A Story of Psychiatric Treatment Resistance: https://unshrunkthebook.com Laura’s website: https://www.lauradelano.com Inner Compass Initiative: https://www.theinnercompass.org Laura on X: https://x.com/LauraDelano Learn more about your ad choices. Visit megaphone.fm/adchoices

Drive with Dr. Peter Attia: Read the notes at at podcastnotes.org. Don't forget to subscribe for free to our newsletter, the top 10 ideas of the week, every Monday --------- View the Show Notes Page for This Episode Become a Member to Receive Exclusive Content Sign Up to Receive Peter’s Weekly Newsletter This is part one of a two-part mini-series on fertility and reproductive health, with next week's guest, Dr. Paula Amato, focusing on the female side of the equation. Paul Turek is a world-renowned expert in male fertility and reproductive health, the founder and medical director of the Turek Clinic, and host of the Talk with Turek podcast. In this episode, Paul explores the topic of male fertility, offering a detailed look at the complex and highly coordinated process of conception and the many challenges sperm face on their journey to fertilizing an egg. He shares fascinating insights into how sperm work together to navigate the female reproductive tract, how environmental factors like heat, stress, and toxins impact sperm quality, and what men can do to improve their reproductive health. Paul also dispels common myths about testosterone replacement therapy and its effects on fertility, providing strategies for preserving fertility while on TRT. The episode also highlights cutting-edge advances in reproductive medicine, from genetic testing and sperm sorting to emerging treatments for infertility. We discuss: The incredibly complex and hostile journey sperm must take to fertilize an egg [3:00]; How sperm are made: meiosis, genetic variation, and the continuous renewal influenced by environmental factors [9:00]; The built-in filter that weeds out genetically abnormal sperm [14:45]; How sperm are finalized in form and function: tail formation, energy storage, and chemical sensing abilities [18:30]; How to optimize conception through the timing of sex, ejaculation frequency, and understanding the sperm lifecycle [26:30]; Male infertility and Paul’s diagnostic approach: detailed history, a physical exam, and identifying red flags [33:30]; Viral infections that can affect the testes and potentially lead to sterility [40:30]; Semen analysis: morphology, motility, and hormonal clues to male fertility [45:45]; Effects of medication, microplastics, stress, and exercise on fertility [57:15]; Testosterone replacement therapy (TRT) and male fertility [1:06:00]; Restoring fertility after prolonged use of exogenous testosterone [1:25:00]; Effects of heat and cold exposure on fertility and sperm quality [1:36:00]; How different levels of exercise—especially cycling—affect male fertility [1:41:45]; How alcohol, marijuana, and nicotine affect male fertility [1:46:00]; Why type 2 diabetes is a risk factor for male infertility [1:50:00]; How varicoceles—a common cause of male infertility—are diagnosed and treated [1:51:15]; Genetic factors that affect fertility [1:54:00]; The impact of lifestyle and environmental exposures on fertility [1:56:30]; The evidence (or lack thereof) behind stem cell and PRP therapies for male infertility, and how lifestyle and non-invasive interventions often lead to successful conception [2:00:30]; Considerations for sperm banking, and how paternal age impacts fertility planning and offspring health [2:05:00]; Semen quality as a biomarker: linking male fertility, longevity, and preventative health through Medicine 3.0 and epigenetics [2:14:45]; and More. Connect With Peter on Twitter, Instagram, Facebook and YouTube