The People's Pharmacy

In this episode, investigative journalist Gardiner Harris delves into the dark secrets of one of the country’s most admired pharmaceutical firms. Johnson & Johnson sold talcum powder–Johnson’s Baby Powder–for decades even though it contained asbestos, an acknowledged carcinogen. How did the company maintain its superb reputation for so long? You could listen through your local public radio station or get the live stream on Saturday, May 10, 2025, at 7 am EDT on your computer or smart phone (wunc.org).  Here is a link so you can find which stations carry our broadcast. If you can’t listen to the broadcast, you may wish to hear the podcast later. You can subscribe through your favorite podcast provider, download the mp3 using the link at the bottom of the page, or listen to the stream on this post starting on May 12, 2025. Dark Secrets: Johnson’s Baby Powder was as American as apple pie. The company counted on the emotional associations with its baby products. The fragrance of its Baby Powder was linked to feelings of love and security. That was smart marketing. Continuing to sell a product contaminated with asbestos was something else, though. How did the company deal with this problem? And what did it tell the FDA? What About Tylenol? Johnson’s Baby Powder is not the only iconic product the company sells. Tylenol is another famous J&J product. Johnson & Johnson has long promoted this pain reliever as one that hospitals and doctors trust. Advertising does not feature the fact that the recommended dose and the maximum safe dose of the active ingredient, acetaminophen, are extremely close. As a result, people can inadvertently overdose, especially if they are taking several different types of medicine for symptoms of a cold or the flu, for example. Exceeding the maximum dose of acetaminophen puts a strain on the liver and, over time, may cause liver injury. This is especially worrisome if someone drinks alcohol on a regular basis. J&J’s response to a crisis in which Tylenol was deliberately adulterated with poison is held up to business students as a case study in doing the right thing. The company pulled millions of bottles off shelves and introduced tamper-proof packaging. This decision bolstered the company’s reputation. The Dark Secrets of the Opioid Crisis: Not all of the company’s business decisions are so laudable, and most are not so well-known. Few people are aware that the Johnson & Johnson company developed fentanyl, a potent opioid. It was originally invented by Dr. Paul Janssen, head of Janssen Pharmaceutica. When J&J acquired Janssen, it also acquired the rights to fentanyl, which it sold in a transdermal formulation as Duragesic. According to our guest, the company initially presented it to physicians as a non-addicting pain reliever. You are no doubt aware that is far from the case. Johnson & Johnson’s Antipsychotic Drugs: Gardiner Harris points out that Johnson & Johnson was one of the first companies to offer “atypical” antipsychotics such as Risperdal (risperidone). This drug, also developed by Janssen, was originally designed to treat the symptoms of schizophrenia. That market is relatively small, however. Later, the company started suggesting to doctors that they could prescribe it for elderly dementia patients who were agitated. Like other antipsychotic drugs, though, Risperdal increases the possibility that such patients will die prematurely from heart problems or infection. The FDA has not approved it for treating dementia-related psychosis. In 2013, J&J agreed to pay $2.2 billion in fines for its marketing of Risperdal and two other drugs. Johnson & Johnson Responds: A spokesperson for the company responded to our request for comment: “We stand behind the safety of our products and are focused on what we do best: delivering medical innovation for patients around the world.” This Week’s Guest: Gardiner Harris previously served as the public health and pharmaceutical reporter for The New York Times and is now a freelance investigative journalist. He also served as a White House, South Asia, and international diplomacy reporter for the Times. Before that, he was a reporter for The Wall Street Journal, covering the pharmaceutical industry. His investigations there led to what was then the largest fine in the history of the Securities and Exchange Commission. He won the Robert Worth Bingham Prize for investigative journalism and the George Polk Award for environmental reporting after revealing that coal companies deliberately and illegally exposed miners to toxic levels of coal dust. Harris’s novel, Hazard, draws on his experience investigating these conditions. His latest book is No More Tears, the Dark Secrets of Johnson & Johnson. The People’s Pharmacy is reader supported. When you buy through links in this post, we may earn a small affiliate commission (at no cost to you). Gardiner Harris, author of No More Tears, the Dark Secrets of Johnson & Johnson (c) Erin Champ Listen to the Podcast: The podcast of this program will be available Monday, May 12, 2025, after broadcast on May 10. It contains some additional discussion of the relationships between drug companies and the FDA, specifically with regard to the role of user fees. We also find out about Procrit (EPO) and why it too was a source of controversy. You can stream the show from this site and download the podcast for free, or you can find it on your favorite platform. Download the mp3, or listen to the podcast on Apple Podcasts or Spotify.

This week, Joe and Terry discuss liver health with two specialists. You may not have spent much time thinking about your liver. It is, however, an absolutely essential organ. When the liver is working properly, every part of the body gets the nutrients it needs and no parts are exposed to damaging toxins. These are among its superpowers. Find out why you should love your liver. You could listen through your local public radio station or get the live stream on Saturday, May 3, 2025, at 7 am EDT on your computer or smart phone (wunc.org). Here is a link  so you can find which stations carry our broadcast. If you can’t listen to the broadcast, you may wish to hear the podcast later. You can subscribe through your favorite podcast provider, download the mp3 using the link at the bottom of the page, or listen to the stream on this post starting on May 5, 2025. Love Your Liver: Nutrients don’t go directly from the intestines to the rest of the body. Instead, they pass through the liver first. There, this master organ breaks them down into compounds that can be recognized and utilized by individual tissues and cells. Moreover, if it finds nasty chemicals that shouldn’t be there, it utilizes its superpowers to transform them into less damaging compounds that can be more readily excreted. You should also love your liver because it can store nutrients for unanticipated periods of fasting and hold off starvation. This was a tremendous benefit during earlier periods of human evolution. These days, we have less need for a hedge against starvation. In fact, when we overload our livers with alcohol or sugar, even its superpowers may not be adequate. The liver’s response to this kind of insult is fibrosis, a condition in which it stiffens and stores fat. Liver Disease: One of the liver’s superpowers is that it can regenerate itself so long as we remove the source of injury. That’s pretty remarkable! But what if we keep on eating ultra-processed foods (Nutrients, May 10, 2023) and drinking soda or alcohol?  In that case, the liver continues to try to repair itself. That can change the architecture of the tiny blood vessels that run through the liver, raising the pressure within them and ultimately leading to serious complications. Fatty liver disease, correctly termed metabolic-associated steatohepatitis (MASH), is the first step; cirrhosis and ultimately liver failure might follow. How Do You Know If Your Liver Is Healthy? The liver is so effective at maintaining the body in balance that most people don’t develop symptoms of trouble until liver disease is quite advanced. As a result, the best way to keep tabs on liver health is through blood tests. Tests for the liver enzymes called ALT and AST are common and often used to assess liver health. Agents That Can Help or Harm the Liver: If you love your liver, consider drinking a cup or two of black coffee daily. This has been shown to help the liver fight inflammation and overcome early-stage liver fibrosis (Redox Biology, March 2025). Another precaution to take: avoid excess acetaminophen. This is the pain-relieving ingredient in Tylenol and hundreds of other over-the-counter medications. Doctors consider it safe for occasional use at doses under 4,000 mg in a day. Chronic use might call for lower doses yet. Because it is so widespread, people may mistakenly take several different medicines containing acetaminophen (paracetamol in the rest of the world) and end up exceeding the maximum dose by accident. Liver experts like our guest Dr. Ahmad treat such emergencies with a medicine called N-acetylcysteine. Other pain relievers, such as NSAIDs, are less likely than acetaminophen to damage the liver. Dangerous reactions to such drugs are unpredictable, however, which can make them harder to manage. Fluoroquinolone antibiotics such as Levaquin and corticosteroids like methylprednisolone also fall into this category. Oral antifungal drugs can also be very hard on the liver. Herbs That Can Challenge the Liver: Pharmaceuticals are not the only compounds that may test the liver’s detoxifying superpowers. Botanical medicines can also cause challenges. Dr. Ahmad has treated people whose liver injuries were caused by green tea extract, turmeric, kratom or ashwagandha. Most people taking such supplements are attempting to improve their health, so discovering that instead they have developed liver damage is a nasty surprise. If you love your liver, stick with drinking green tea and eating curry rather than taking pills with concentrated extracts. This Week’s Guests: Meena Bansal, MD, is Professor of Medicine, specializing in liver diseases, at the Icahn School of Medicine at Mount Sinai. She is System Chief of the Division of Liver Diseases and Director of the MASH/NASH Center of Excellence at Mount Sinai. Meena Bansal, MD, Professor of Medicine Mt. Sinai, photo courtesy of Mt. Sinai Jawad Ahmad, MD, is a professor of liver diseases at the Mount Sinai School of Medicine. He is co Primary Investigator on the NIH/NIDDK research initiative to study cases of severe liver injury caused by prescription drugs, over-the-counter drugs, and alternative medicines, such as herbal products and supplements. For more information on the Drug-Induced Liver Injury Network (DILIN) visit: https://researchfunding.duke.edu/drug-induced-liver-injury-network-dilin-clinical-centers-u01-clinical-trial-optional Jawad Ahmad, MD, Professor of Medicine at Mount Sinai, photo courtesy of Mt. Sinai Listen to the Podcast: The podcast of this program will be available Monday, May 5, 2025, after broadcast on May 3. You can stream the show from this site and download the podcast for free. Download the mp3, or listen to the podcast on Apple Podcasts or Spotify.

This week, a renowned neurosurgeon shares what he has learned in decades of working to restore ailing brains. His new book covers a vast range of neuroscience. Our dilemma was what to pay attention to in all those options. In a sense, that is always the human situation. We are capable of conscious processing of approximately 200 bits per second (bps) of information. Our unconscious brain deals with as much as 11 million bps. You could listen through your local public radio station or get the live stream Saturday, April 26, 2025, at 7 am EDT on your computer or smart phone (wvtf.org).  Here is a link so you can find which stations carry our broadcast. If you can’t listen to the broadcast, you may wish to hear the podcast later. You can subscribe through your favorite podcast provider, download the mp3 using the link at the bottom of the page, or listen to the stream on this post starting on April 28, 2025. The Power of the Unconscious Brain: Our senses feed us a tremendous amount of information all the time, but we don’t have the bandwidth to pay attention to more than a small fraction of it. That’s where the unconscious brain is so valuable, juggling millions of bits of information while we focus our conscious attention on what seems important. One surprising outcome of the research on how our brains function is a re-assessment of what is going on when people are unconscious. For centuries, doctors thought there was really no brain activity while a person was comatose. Then, a few decades ago, a scientist was recording the brain waves of a patient in a coma. The activity was very peculiar, as if the person were watching a ball being lobbed back and forth across a tennis court. In actuality, a television set in the room was broadcasting a world championship match between Roger Federer and Rafael Nadal. The neuroscientist recognized that this individual was following the match and was not nearly as deeply unconscious as had been thought. Further research showed that this kind of unconscious brain activity is not uncommon. It may hold keys to determining who has the best potential for recovering from their coma. Freud and the Unconscious Brain: If you hear the term the unconscious mind, you may think of Sigmund Freud. He really popularized the concept that some very important brain activity takes place outside of our conscious awareness. It still has a powerful influence on our behavior. By the way, if we recognize that our conscious attention is indeed a limited resource (200 bps, remember), we won’t try to multitask. Humans actually aren’t very good at multitasking; instead, we switch our attention from one thing to another. Some people can do that fairly easily, but for most of us, it is less effective than staying focused. Three Stages of Brain Development: Evolution likes to build on what it’s already got in place, so it shouldn’t surprise us that we can track three different evolutionary stages to our human brains. The reptilian brain came first, of course, and is there as a base, operating mostly on reflex. It’s definitely an important part of the unconscious brain. The mammalian brain brings in emotions. The hormone oxytocin is relevant for this discussion. It is critical for birthing and nursing young. As it turns out, oxytocin can also be put to other uses, such as bonding mates together and creating friends. Finally, we have the primate part of our brain. We humans, like other primates, can exercise empathy because our mirror neurons allow us to relate to another creature’s experience. In fact, mirror neurons were discovered by scientists studying macaques and eating gelato. Listen for a great story! Speaking of empathy, we wondered about empathy fatigue. We started hearing about empathy fatigue during the COVID pandemic, when healthcare providers were overwhelmed by extreme demands with inadequate support. Research shows that “constant, repetitive exposure to the pain of others leads to empathy fatigue.” Lack of empathy can lead people to do terrible things. Wonders of the Unconscious Brain: Our brains are full of clocks. To some extent, these are shaped by how we use them. Musicians who play percussion instruments can perceive time differences of just a few hundredths of a second. All of us are entrained to a 24-hour a day cycle, whether we observe sunrise and sunset or not. But if we are deprived of connection with that cycle, our internal clocks can’t keep good time, and our brains may get far off track. What About Premonitions? Some people think premonitions are a fantasy. Yet this is another area where our unconscious brain may be more capable than we imagine. Dr. Hamilton describes an experience in the Swiss Alps where he and his wife had a choice of which path to take down from the summit. One appeared to be a shortcut, and they did have some time constraints. But as soon as they had taken a few steps that direction, he had a premonition of something terrible. They took the other path and learned later that there had been a landslide on the shortcut that would have swept them helplessly down the mountain. According to Dr. Hamilton, some people have the ability to influence the output of random number generators. Those of us who can’t may wish to reject that idea, but it has been documented. The Princeton Engineering Anomalies Research lab has run many studies demonstrating an impact on random number generations, not to mention remote viewing. In this way, some of the hidden power of the unconscious brain appear as cerebral entanglements, analogous to quantum entanglements at the sub-atomic level of matter. This Week’s Guest: Dr. Allan Hamilton, MD, FACS, is a neurosurgeon who has specialized in treating brain tumors. His extraordinary journey from janitor to Harvard-trained neurosurgeon is just the beginning of his remarkable story. A decorated Army veteran, he now holds four professorships at the University of Arizona and has been recognized as “One of the Leading Intellects of the Twenty-First Century.” As the only American honored with the Lars Leksell Award for pioneering scientific discovery in stereotactic neurosurgery, Dr. Hamilton’s groundbreaking work has revolutionized the field. He has had a life-long interest in the application of computer technologies to enhance surgical care and reduce avoidable medical adverse events. In addition, he has served on two White House Advisory Committees under two presidential administrations. Allan Hamilton, MD, FACS His expertise extends beyond medicine, having studied creative writing under Rod Serling and serving as a senior medical consultant for Grey’s Anatomy for nearly two decades. Dr. Hamilton’s seven non-fiction books have garnered numerous awards and international translations, offering insights that have inspired leaders across various fields. Dr. Hamilton’s 7th non-fiction book is Cerebral Entanglements: How the Brain Shapes Our Public and Private Lives. The People’s Pharmacy is reader supported. When you buy through links in this post, we may earn a small affiliate commission (at no cost to you). Listen to the Podcast: The podcast of this program will be available Monday, April 28, 2025, after broadcast on April 26. You can stream the show from this site and download the podcast for free. Download the mp3, or listen to the podcast on Apple Podcasts or Spotify.

In this engaging conversation with Dr. Mark Hyman, a leading functional medicine expert, listeners learn how to measure biological age versus chronological age. He shares vital insights on nutrition, advocating for the Mediterranean diet and its role in preventing chronic diseases. Hyman discusses the transformative power of functional medicine, emphasizing the need to address root causes of health issues. Practical tips on dietary strategies, including the importance of a nutritious breakfast and innovative recipes, make health both achievable and delicious.

David Nichols, an authority on hallucinogens from UNC Chapel Hill, and Matthew Johnson, a psychiatric researcher at Johns Hopkins, discuss the evolving landscape of psychedelic therapy. They explore how psychedelics like LSD, traditionally stigmatized, are now being researched for mental health treatment, including addiction and cancer-related distress. Notably, they highlight a modified LSD that lacks hallucinogenic effects but may enhance neuroplasticity. Their insights shed light on the potential revolution in mental health care through these once-taboo substances.

David Kaylie, a neuro-otologist at Duke Health, dives into the intricacies of dizziness and balance disorders. He explains the differences between vertigo and lightheadedness, exploring conditions like Menière disease and BPPV. Listeners learn about potential treatment options, including the Epley Maneuver and beta histine for Menière's. Personal stories from callers enrich the discussion, emphasizing the impact of these conditions on daily life. Kaylie also shares insights on managing symptoms and navigating communication with healthcare providers.

This week, two pharmacists describe why you should check with a pharmacist about possible problems when you combine supplements, herbs and medicines. In some cases, a supplement might interfere with your prescription drug. In other situations, an herb might slow metabolism of the medicine and increase the possibility of side effects. It’s better to know which pills don’t get along well. You could listen through your local public radio station or get the live stream at 7 am EDT on your computer or smart phone (wunc.org).  Here is a link  so you can find which stations carry our broadcast. If you can’t listen to the broadcast, you may wish to hear the podcast later. You can subscribe through your favorite podcast provider, download the mp3 using the link at the bottom of the page, or listen to the stream on this post starting on April 7, 2025. Getting Information on Supplements & Herbs: When you have a question about supplements or herbs, you probably go to the web for answers. But while there is plenty of information out there, not all of it is reliable. We start this episode by talking with a pharmacist who does research for one of the sites we use as a favorite resource, Examine.com. The site has long provided information on what a product is supposed to do and how well it might do that thing. It also offers information on dosing and on quality. For example, if you look up turmeric, you’ll learn that Meriva and BCM95 are standardized extracts that have been used in a number of randomized controlled trials. Now, Examine is going beyond efficacy and looking at safety. Because there is less information available about safety, even for medications, this has been more challenging. We especially appreciate that the summaries are succinct and easy to understand and that the statements are supported by peer-reviewed research. Checking Examine.com is a good place to start learning about potential incompatibilities among supplements, herbs and medicines you are taking. What Does Grapefruit Have to Do with It? We recognize that grapefruit is not an herb or a supplement. It is certainly not a medication, although it is a great source of vitamin C and regular consumption of grapefruit can help control cholesterol (Metabolism, July 2012).  Nonetheless, it is important to our topic, because scientists discovered a potent interaction between grapefruit juice and certain prescription drug many decades ago (Lancet, Feb. 2, 1991). Although grapefruit inhibits the CYP3A4 enzyme that metabolizes many medicines, it is not the only plant product that can affect them. This was a wake-up call for us and for many health professionals to pay attention to interactions among supplements, herbs and medicines. Like grapefruit, both ginger and berberine inhibit CYP3A4. St. John’s wort, on the other hand, induces the enzyme, which means that the target medication may be less effective. If it is an oral contraceptive or a drug to prevent transplant rejection, you need to know that! How Pharmacists Can Help: Pharmacists stand ready to help people review their supplements, herbs and medicines to see if there are potential interactions, redundancies, adverse reactions or other problems. Technically, everyone on Medicare is entitled to a comprehensive medication review annually. Some pharmacists like to conduct that as a “brown bag review,” in which the patient brings in everything they are taking–OTC med, prescription drugs, herbs, vitamins and other dietary supplements–so the pharmacist gets a complete picture. Sometimes, it may even be helpful to talk about food and drink. We already mentioned grapefruit. During this interview, we also bring up research showing that hibiscus tea (which can lower blood pressure) could interact with the cholesterol-lowering drug simvastatin (Journal of Clinical Pharmacy and Therapeutics, Dec. 2017).  Hibiscus tea itself lowers cholesterol well. However, it interacts with simvastatin and reduces the drug’s effectiveness. The authors of the study advise against co-administration. This Week’s Guests: Katie Jantz, MS, RPh is a researcher on the staff for Examine.com. Katie Jantz, MS, RPh Stefanie Ferreri, PharmD, is the Henry L. Smith and James L. Olsen, Ph.D., Distinguished Professor in Pharmacy Practice. She has served as the Chair of the Division of Practice Advancement and Clinical Education at the UNC Eshelman School of Pharmacy. Her main research interests include advancing clinical practice in the community-pharmacy setting.
https://pharmacy.unc.edu/directory/ferreri/ Stefanie Ferreri, PharmD Listen to the Podcast: The podcast of this program will be available Monday, April 7, 2025, after broadcast on April 5. You can stream the show from this site and download the podcast for free. download the mp3.

This week, we talk with a pulmonologist–a doctor who takes care of people with lung problems. Our topics range from common respiratory infections to the hazards of breathing smoke from forest fires. We also discuss asthma and COPD. Listen to find out how you could be breathing better. You could listen through your local public radio station or get the live stream at 7 am EDT on your computer or smart phone (wunc.org).  Here is a link so you can find which stations carry our broadcast. If you can’t listen to the broadcast, you may wish to hear the podcast later. You can subscribe through your favorite podcast provider, download the mp3 using the link at the bottom of the page, or listen to the stream on this post starting on March 31, 2025. Breathing Better Despite Infections: We are finally emerging from an especially severe flu season. After a few years during and right after the pandemic in which there was relatively little influenza, this year was challenging. Preliminary data from the CDC suggest that between 40 million and 75 million Americans suffered from influenza or flu-like illnesses between October and March. As many as 1.2 million had to be hospitalized. The influenza viruses (there are many) are not the only pathogens that can cause coughing, fever or trouble breathing. Many others might also result in upper respiratory infections that can progress to bronchitis or lower respiratory infections and lead to wheezing or shortness of breath. A bad cold will do that for some people. Human metapneumovirus is not widely recognized and is difficult to pronounce. The infection with this virus starts like a bad cold but it produces a terrible cough that can last for weeks. How can doctors help a patient with a respiratory infection? If the problem is influenza, they could prescribe a medicine such as oseltamivir (Tamiflu) or baloxavir (Xofluza). These medicines can shorten the duration of flu symptoms and possibly make them less severe. However, they work best when taken as soon as possible (within 48 hours) of the first symptoms appearing. To learn whether that sore throat and sniffle is leading to flu, you might want to keep a test handy at home. There are several on the market that can determine if you have COVID-19 or influenza A. Then, if you have access to a patient portal, use it to communicate the results to your healthcare provider and get a prompt prescription. What About a Cold? While flu or COVID can be serious, colds are far more common. Doctors do not have much in their tool kits to help you recover from a cold, but there are a few things you can do for yourself. Spending some time in sunlight can be very useful. Dr. Seheult suspects that the benefits go beyond the amount of vitamin D you might make through that exposure. In addition, we have seen studies supporting the use of vitamin C supplements to recover from a cold more quickly. Breathing Better with Improved Ventilation: During the pandemic, air quality and ventilation got more attention than ever before. Now, although we may be less concerned about airborne pathogens, we still need to pay attention to air quality. Forest fires, whether in California, the Carolinas or any other part of the continent, can put out a lot of smoke. Wildfire smoke carries small particles that can penetrate deep in the lungs and do a lot of damage. Air conditioning may help clean indoor air. So can an inexpensive do-it-yourself air filtering system called a Corsi-Rosenthal box. Here is a link to the show in which we describe how to make one at home. Struggling to Exhale: Dr. Seheult also describes the Global Initiative for Asthma, or GINA.  Asthma is reversible airway inflammation. Sometimes this is caused by allergic reactions. Infections may also cause inflammation and lead to asthma exacerbations. In the presence of inflammation, the smooth muscle around the little airways deep in the lungs constrict. This makes it difficult to exhale and make room for the next fresh new breath. The problem is similar in chronic obstructive pulmonary disease (COPD), in that inflammation tightens those critical small airways and interferes with exhalation. That in turn can keep the patient from being able to take a good breath in. In COPD, however, the inflammation is irreversible. Both asthma and COPD may respond to drugs that activate beta receptors (“beta agonists”). The long-acting beta agonists (LABAs) are especially prominent. Inhaled steroids can calm the inflammation in both conditions so people can start breathing better. In some instances, an antibiotic like azithromycin can reduce exacerbations. We don’t know whether it is working by fighting off hidden pathogens, or whether it is also reducing inflammation. In COPD, anticholinergic drugs may be able to relax airways even beyond the effects of the beta agonists. If calming inflammation is not good enough, people may need a rescue inhaler. When Should You Get Emergency Attention? People experiencing shortness of breath, especially if they are also having fevers, chills or night sweats, should get medical attention promptly. This Week’s Guest: Dr. Roger Seheult is an Associate Clinical Professor at the University of California, Riverside School of Medicine, and an Assistant Clinical Professor at the School of Medicine and Allied Health at Loma Linda University. Dr. Seheult is quadruple board-certified in Internal Medicine, Pulmonary Diseases, Critical Care Medicine, and Sleep Medicine through the American Board of Internal Medicine. HIs current practice is in Beaumont, California where he is a critical care physician, pulmonologist, and sleep physician at Optum California. He lectures routinely across the country at conferences and for medical, PA, and RT societies, is the director of a sleep lab, and is the Medical Director for the Crafton Hills College Respiratory Care Program. Roger Seheult, MD, MedCram, Loma Linda, UC-Riverside MedCram In 2012 he and Kyle Allred founded MedCram L.L.C., a medical education company with CME-accredited videos that are utilized by hospitals, medical schools, and hundreds of thousands of medical professionals from all over the world (and over 1 million YouTube Subscribers). His passion is “demystifying” medical concepts and offering people the tools for staying healthy. We have found Dr. Seheult’s MedCram videos amazing. He makes many complex medical topics understandable. This is a skill that few of Joe’s professors in the University of Michigan’s Department of Pharmacology could claim. Dr. Seheult was the recipient of the 2021 San Bernardino County Medical Society’s William L. Cover MD Award for Outstanding Contribution to Medicine and the 2022 UnitedHealth Group’s The Sages of Clinical Service Award. In 2022 both Roger Seheult and Kyle Allred received the HRH Prince Salmon bin Hamad Al Khalifa Medical Merit Medal from the Kingdom of Bahrain for their contribution to health policy in the Kingdom of Bahrain. Listen to the Podcast: The podcast of this program will be available Monday, March 31, 2025, after broadcast on March 29. You can stream the show from this site and download the podcast for free. In addition to what you hear on the broadcast, the podcast also contains information about TRP channels and home remedies for coughs. We also discuss the heart drug amiodarone and its effects on the lung, along with the nature of interstitial lung disease and how to treat it. You’ll also learn about the pros and cons of OTC inhalers. Can they get you breathing better? Download the mp3.

This week, Dr. Jane Andersen joins Joe and Terry in the studio to answer listeners’ questions about foot problems. Do you have bunions or plantar fasciitis? Dr. Andersen has tips on how to fix your foot pain. We invite you to call and tell us about it. You can call 888-472-3366 between 7 and 8 am EDT. Or email us: radio@PeoplesPharmacy.com. You could listen through your local public radio station or get the live stream at 7 am EST on your computer or smart phone (wunc.org).  Here is a link so you can find which stations carry our broadcast. If you can’t listen to the broadcast, you may wish to hear the podcast later. You can subscribe through your favorite podcast provider, download the mp3 using the link at the bottom of the page, or listen to the stream on this post starting on March 24, 2025. How Can You Fix Your Foot Pain? If your feet don’t feel good, you won’t either. Just imagine stubbing your toe. Ouch, that hurt! But stubbed toes generally recover fairly quickly. Some other common foot problems are likely to cause more long-lasting pain. Some of these may result from participation in sports, such as sprained ankles or stress fractures. What is the best way to handle these injuries so they won’t cause persistent problems? Preventing Foot Pain: Are your feet flat? Find out what exercises may help and which shoes you should choose to fix your foot pain from flat feet. Heel pain is another common problem. Inflammation of the Achilles tendon is one possible cause. Perhaps more often, plantar fasciitis triggers heel pain. That is an inflammation of the tissue connecting the heel and the ball of the foot, and special stretches can often help. If you have wondered about heel spurs or neuromas, tell us what you would like to know. Restoring feet to good health can cover a lot of different areas. Toes and Toenails: How about toes? Find out what to do about hammertoes, mallet toes or claw toes, as well as bunions. Are you worried about gout? It may affect the toes first, before causing pain in other parts of the body. With warmer weather on the way, you may be interested in learning how to prevent athletes foot or eliminate toenail fungus. Do you have corns or calluses on your feet? What is the difference between them, and do the treatments differ? The questions listeners ask drive the topics we discuss in this show. You can email questions ahead of time to: radio@peoplespharmacy.com. This Week’s Guest: Dr. Jane Andersen, Board Certified, American Board of Foot and Ankle Surgery, is in practice at Chapel Hill Foot and Ankle, part of FASMA, Foot and Ankle specialists of the Mid Atlantic, in Chapel Hill, North Carolina. Dr. Andersen specializes in Foot and ankle care for Children, Adults, Athletes and Geriatric Patients including surgery and conservative care. She is a Trustee of the American Podiatric Medical Association. January 18, 2025, Jane Andersen, DPM, was awarded the Edwin B. Martin, Jr., Award for Podiatrist of the Year. Dr. Jane Andersen can help you manage your foot problems. Listen to the Podcast: The podcast of this program will be available Monday, March 24, 2025, after broadcast on March 22. You can stream the show from this site and download the podcast for free. Download the mp3.

This week, our guests take two different approaches to the sense of smell. We talk with a surgeon who treats people having difficulties with that sense. In addition, a nurse describes utilizing the sense of smell for aromatherapy in integrative healing. Learn about the fascinating science of smell. You could listen through your local public radio station or get the live stream at 7 am EDT on your computer or smart phone (wunc.org). Here is a link so you can find which stations carry our broadcast. If you can’t listen to the broadcast, you may wish to hear the podcast later. You can subscribe through your favorite podcast provider, download the mp3 using the link at the bottom of the page, or listen to the stream on this post starting on March 17, 2025. The Science of Smell: Of all our senses, the sense of smell often gets short shrift. Aside from Marcel Proust’s evocative description of the link between odor and memory, we don’t think much about smell. Scientists have discovered, however, that much of our social interaction relies on olfaction at a subconscious level. It plays a largely unconscious role in our choice of mates as well as in the timing of sexual activity. It is also important for the bonding between mothers and their infants. Consequently, the sense of smell is crucial for the survival of our species, even when we aren’t paying attention. Losing our sense of smell can be devastating, as too many people learned by experience during the COVID-19 pandemic. Not only did they miss out on pleasant aromas like fresh-brewed coffee or newly mown grass, but they also were at a disadvantage in detecting if there might be gas leaking in the kitchen or a fire smoldering somewhere in the house. Although some of those who lost their sense of smell during an acute infection subsequently regained it, others did not. Too many people are still suffering from anosmia. Is there anything that can be done to help them? Regenerating Nerves in the Nose: Many viruses can cause inflammation in nasal tissue and potentially damage the sense of smell. During COVID-19, the SARS-CoV-2 virus attacked ACE receptors on cells in the olfactory epithelium of the nose. These cells are not the nerve cells themselves, but support cells (called, if you must know, sustentacular cells). Fortunately, these cells can regenerate, although it takes time. The Science of Smell Recovery–Olfactory Training: The first step in recovering the sense of smell is olfactory training. It could be considered something like physical therapy for the nose. In this structured smelling protocol, people are exposed to one of four distinctive aromas from essential oils: lemon, rose, eucalyptus or clove. As they attempt to discern the scent, they remember how they used to experience those odors. As part of the protocol, they also irrigate their nasal passages with high-dose steroids in saline solution (International Forum of Allergy & Rhinology, Sep. 2018).  Over many months, this concerted effort is able to help 30 to 50 percent of patients recover their sense of smell to a satisfactory degree. The Science of Smell Recovery–Platelet-Rich Plasma: To help people who are not successful enough with olfactory training, Dr. Zara Patel has pioneered the use of platelet-rich plasma. PRP injections have been used to help athletes recover from injury. Since it can be helpful in situations where inflammation is high, she tried PRP injections for people with difficulty smelling. A randomized controlled trial showed that the injection is safe and may be effective in helping people recover their sense of smell after COVID-19 (International Forum of Allergy & Rhinology, June 2023).  She hopes to conduct a larger study that would be more conclusive. Harnessing the Sense of Smell with Aromatherapy: Dr. Patel was careful to point out the distinction between olfactory training, based on the science of smell, and aromatherapy. Our other guest, an integrative care nurse, utilizes aromatherapy to help people in post-anesthesia care units. There is some evidence, for example, that the aroma of lavender essential oil can help anxious patients relax and get to sleep, but better studies are necessary (Phytomedicine, Dec. 2019). Plants use the volatile compounds in their essential oils for communication. In addition, some terpenes in juniper or pine have antiviral activity, while components in clary sage or bergamot have antifungal properties. Nurses in some cancer hospitals utilize aromatherapy to help patients overcome nausea and pain associated with chemotherapy. This is an area of the science of smell in which our guest Kathy Fritze has special expertise. This Week’s Guests: Zara M. Patel, MD, is Professor of Otolaryngology-Head and Neck Surgery at the Stanford School of Medicine. Her website is https://profiles.stanford.edu/zara-patel Zara Patel, MD, Stanford School of Medicine Kathy Fritze, RN, BSN, is a holistic and integrative care nurse in the Wellness & Support Center at the University of Maryland St. Joseph Medical Center. Kathryn Fritze RN, BSN Listen to the Podcast: The podcast of this program will be available Monday, March 17, 2025, after broadcast on March 15. You can stream the show from this site and download the podcast for free. In addition to what you heard in the broadcast, the podcast includes additional information on why people sometimes detect strange odors that others don’t perceive. We also discuss people who have strong reactions to odors in perfume or detergent, such that they become physically ill when they smell them. Download the mp3.