
AI and I
Learn how the smartest people in the world are using AI to think, create, and relate. Each week I interview founders, filmmakers, writers, investors, and others about how they use AI tools like ChatGPT, Claude, and Midjourney in their work and in their lives. We screen-share through their historical chats and then experiment with AI live on the show. Join us to discover how AI is changing how we think about our world—and ourselves.
For more essays, interviews, and experiments at the forefront of AI: https://every.to/chain-of-thought?sort=newest.
Latest episodes

66 snips
Apr 17, 2024 • 1h 1min
Reid Hoffman on How AI is Answering Our Biggest Questions—Ep. 18 with Reid Hoffman
In this engaging discussion, Reid Hoffman, the founder of LinkedIn and a philosophy enthusiast, explores how philosophy can enhance business acumen. He argues that philosophical training equips founders to tackle complex existential questions and promotes interdisciplinary thinking. The conversation dives into AI's role in shaping human cognition and the essentialist vs. nominalist views in language models. Reid also shares practical ways to use ChatGPT for clear thinking and creative exploration, making this a thought-provoking listen for anyone intrigued by humanity's evolving relationship with technology.

90 snips
Apr 10, 2024 • 1h 14min
This Best-selling Author Wrote a Book in 30 Days—With ChatGPT - Ep. 17 with Seth Stephens-Davidowitz
Seth Stephens-Davidowitz, a data scientist and author known for "Everybody Lies," shares his journey of writing a book in just 30 days using ChatGPT. He reveals how AI not only accelerated the writing process but also made it more enjoyable. Topics include leveraging AI for data analysis, the evolving role of creativity, and how asking the right questions is crucial in the age of AI. Plus, Seth demonstrates AI live by analyzing Olympic athlete data to discover their ideal sport. It's a fascinating look at AI's potential in writing and beyond!

56 snips
Mar 27, 2024 • 1h 1min
Take Your Business From Zero to One With AI - Ep. 16 with Nicholas Thorne
Nicholas Thorne, a General Partner at Prehype and founder of Audos, is revolutionizing entrepreneurship with AI. He discusses how Audos, an AI chatbot, can quickly transform ideas into pitch decks, websites, and GPTs. Thorne shares his journey of using ChatGPT to prototype features for non-technical entrepreneurs. Key topics include leveraging AI to enhance founder effectiveness, refining business strategies, and automating customer feedback. This conversation is a treasure trove for aspiring entrepreneurs looking to harness AI for innovation.

16 snips
Mar 20, 2024 • 1h 5min
Prozac and ChatGPT: How Technology is Changing the Way We See Ourselves - Ep. 15 with Peter D. Kramer
In this enlightening discussion, psychiatrist Peter D. Kramer shares his insights on how antidepressants like Prozac reshape personality and self-perception. He cites his own experiences and debunks myths around these medications, emphasizing their role in enhancing boldness and emotional resilience. The conversation also explores the parallels between medication and AI technologies like ChatGPT, examining how each impacts human identity and perceptions of mental health. Kramer challenges us to reflect on the future of self-understanding in a tech-driven world.

122 snips
Mar 13, 2024 • 1h 16min
How to Run a Profitable One-person Internet Business Using AI - Ep. 14 with Ben Tossell
Ben Tossell, founder of Ben's Bites and ex-Makerpad CEO, shares his expertise in building a one-person internet business using AI. He explains how to leverage tools like ChatGPT for creating compelling landing pages and analyzing business data. Tossell highlights strategies for navigating market saturation and enhancing newsletter growth, along with effective content creation and interview techniques. Discover how AI can transform your entrepreneurial journey and help streamline operations while maximizing profitability.

14 snips
Mar 1, 2024 • 1h 37min
Can Gemini 1.5 Pro Beat Our Best Stock Trade? - Ep. 13 with Jesse Beyroutey
In a lively conversation, Jesse Beyroutey, a managing partner at IA Ventures, shares insights from his impressive career in venture capital. He discusses how to leverage AI tools like Gemini Pro 1.5 for stock trading and the intricacies of making informed investments. The duo revisits their iconic Nvidia trade and attempts to replicate that success live with a $1,000 investment. They explore the importance of refining queries, analyzing market conditions, and uncovering new opportunities driven by large language models, wrapping up with a surprising plot twist.

8 snips
Feb 28, 2024 • 1h 5min
How a Hollywood Director Uses AI to Make Movies - Ep. 12 with Dave Clark
Dave Clark, a visionary film and commercial director known for viral AI-generated shorts, shares his insights on the fusion of AI and filmmaking. He emphasizes how aspiring filmmakers can leverage AI tools to create cinematic masterpieces from their bedrooms. Topics include using ChatGPT for storytelling, actionable tips for maximizing creative AI tools, and how to craft standout visuals. The highlight is a live creation of a noir short featuring Nicolas Cage, showcasing an innovative blend of humor and technology in storytelling.

234 snips
Feb 21, 2024 • 1h 29min
She’s Running a Business, Writing a Book, and Getting a PhD—with ChatGPT- Ep. 11 with Anne-Laure Le Cunff
Anne-Laure Le Cunff, founder of Ness Labs and a neuroscience PhD candidate, shares her secrets to productivity while juggling a business, writing a book, and pursuing academic goals. She reveals how ChatGPT enhances efficiency by breaking down complex research papers and generating tailored advice. Anne-Laure also discusses using AI to create eye-catching YouTube thumbnails and extract insights from her journaling. Her inspiring journey highlights the balance between technology and creativity for curious minds.

193 snips
Feb 14, 2024 • 1h 59min
How to Find Your Next Big Idea Hiding on the Internet - Ep. 10 with Steph Smith
Steph Smith, host of the a16z podcast and online creator, shares her expert approach to uncovering business ideas on the internet. She discusses how to harness tools like ChatGPT for idea generation and simplifying complex information. Tips on leveraging SEO and examining customer reviews for market insights are shared. The conversation also explores trends from Reddit and innovative product concepts, showcasing how the digital landscape is ripe for entrepreneurship and creativity.

42 snips
Feb 7, 2024 • 1h 45min
How to Make a Video Game With ChatGPT in 60 Minutes - Ep. 9 with Logan Kilpatrick
Logan Kilpatrick, OpenAI's first dev relations hire, shares his passion for empowering creativity with AI. Dive into the world of game development as they create a video game using ChatGPT in just 60 minutes. Discover how AI tools can transform non-developers into creators, the potential for custom GPTs, and ways to make your projects go viral. Logan also discusses the exciting blend of gaming and historical education, making coding more accessible than ever. This conversation is a must-listen for aspiring game developers!