
Once a Scientist
Unfiltered career discussions with scientists
Latest episodes

Apr 23, 2025 • 55min
91. Michael Koeris, Director of DARPA BTO, on autonomous science to accelerate discovery
Episode 91. Michael Koeris is the Director of the Biotechnologies Office at DARPA. Michael completed his PhD at Boston University and did postdoctoral research in synthetic biology at MIT. He spent time early in his career at Flagship Pioneering, is a former founder and executive of multiple biotechs, and was formerly a professor at the Keck Graduate Institute.

Dec 18, 2024 • 1h 18min
90. Barry Bunin, CEO at Collaborative Drug Discovery, on tapping into the collective consciousness of science.
Episode 90. Barry Bunin is the CEO and President at Collaborative Drug Discovery, which he founded 20 years ago. Prior to that, Barry was an Entrepreneur in Residence at Eli Lilly. He completed his PhD in Bioorganic Chemistry at UC Berkeley and his bachelor's degree in chemistry at Columbia University. To learn more about CDD: https://www.collaborativedrug.com/ai-drug-discovery#Bioisosteric-Suggestionshttps://www.collaborativedrug.com/curves#Calculationshttps://www.collaborativedrug.com/automation

Oct 30, 2024 • 1h 5min
89. Seemay Chou, CEO of Arcadia Science, on metascience and rethinking the structure of science
Seemay Chou is co-founder and CEO at Arcadia Science, Board Member at Astera Institute, and Board Chairperson at The Navigation Fund. Seemay was previously an assistant professor at UCSF and completed her PhD in Molecular and Cell Biology at UC Berkeley.

Oct 1, 2024 • 1h 13min
88. Gene Yeo, professor at UC San Diego, on team science and building a training playground
Episode 88. Eugene Yeo is a Professor at UC San Diego and is building a scientific ecosystem in San Diego. He runs the Innovation Center at Sanford Stem Cell Institute, is Scientific Director at the Sanford Consortium, Chief Scientist at the Sanford labs for Innovative Medicines, and Director of UC San Diego’s Center for RNA Technologies and Therapeutics.

Aug 30, 2024 • 1h 4min
87. Jesse Gray and Sud Pinglay, at SeaHub, on recording cellular activity and making big bets
Episode 87. Sudarshan Pinglay is a researcher at the University of Washington and faculty at the Seattle Hub for Synthetic Biology (SeaHub). He did his PhD at New York University and bachelor's degree at Johns Hopkins. Jesse Gray is a Senior Director at SeaHub. He previously worked in industry at Ascidian Therapeutics and as a professor at Harvard Medical School. Jesse completed his PhD at UCSF and his undergrad at University of Wisconsin.

Jul 17, 2024 • 1h 8min
86. Prachee Avasthi, CSO at Arcadia Science, on exercising agency and doing science differently
Episode 86. Prachee Avasthi is co-founder and Chief Scientific Officer at Arcadia Science and Head of Open Science at the Astera Institute. Prachee was previously a professor at Dartmouth and University of Kansas. She completed a PhD in Neuroscience at University of Utah and her bachelor's degree at the University of Illinois Urbana-Champaign.

May 29, 2024 • 47min
85. Fay Lin, science journalist and editor, on seeking out diverse voices and learning from experts
Episode 85. Fay Lin is a Senior Editor at GEN Biotechnology. She completed her PhD in Biochemistry, Molecular, and Structural Biology at UCLA and undergrad in Biology at NYU with minors in Computer Science and Chemistry.GEN Biotechnology website: https://home.liebertpub.com/genbioCall for Papers: Special Issue in AI in Biotechnology: https://home.liebertpub.com/cfp/special-issue-artificial-intelligence-in-biotechnology/497/

Apr 24, 2024 • 1h 18min
84. Maryann Martone, professor at UC San Diego, on neuroinformatics, reproducibility, and open science
Episode 84. Maryann Martone is an emeritus professor of neuroscience at UC San Diego. She received her BA from Wellesley College in Biological Psychology and Ancient Greek and her PhD in Neuroscience from the UC San Diego

Mar 20, 2024 • 1h 21min
83. Anand Muthusamy, Convergent Research fellow, on going after ambitious scientific moonshots
Anand Muthusamy is a Fellow at Convergent Research, where he's laying the groundwork for a focused research organization (FRO) to monitor the real-time activity of biomarkers in humans. Anand is a chemist and neuroscientist. He recently completed his PhD at Caltech, worked at Janelia Research Campus, and did his undergrad at the University of Pennsylvania. Check out his recent paper on bioRxiv: https://www.biorxiv.org/content/10.1101/2024.03.15.584894v1Defense talk on YouTube: https://youtu.be/OK1kBOKsaawFRO proposal overview: https://fas.org/wp-content/uploads/2023/08/Muthusamy-Garrett-Molecular-Modeling.pdf

Jan 31, 2024 • 45min
82. Alexander Titus, professor and entrepreneur, on why scientists make great entrepreneurs
Episode 82. Alexander Titus is a professor at USC, doing research at the intersection of biology and AI. He completed his PhD in Quantitative Biomedical Sciences at Dartmouth. He's also the founder of Bioeconomy.xyz and advises the U.S. Government on AI and national security. Titus spent time at McKinsey and Google and helped build Colossal Biosciences and Form Bio.