
The Mind-Gut Conversation
The Mind-Gut Conversation brings in experts within various fields of health & science to have a discussion with world-renowned gastroenterologist, neuroscientist and bestselling author of The Mind Gut Connection, Emeran Mayer, MD.
Latest episodes

Nov 25, 2024 • 57min
The Human Body Was Not Designed For Illness with Patrick Flynn, DC | MGC Ep. 80
In this episode of The Mind Gut Conversation, I sit down with Patrick Flynn, DC as he shares his bold belief that the human body was not designed for illness and, when properly cared for, has the innate ability to heal itself-a perspective that challenges conventional medical norms.
Dr. Flynn is a trained chiropractor, nationally renowned leader in wellness and the visionary founder of The Wellness Way, a revolutionary network of 80 health restoration clinics across the United States. Beyond his clinical successes, he is the author of two influential books: I Disagree: How These Two Words Are the Secret to Thinking Differently, Taking Control of Your Health (2019) and the follow-up I Still Disagree (2024).
Dr. Flynn is also a Fellow in the American Psychological Association and the American Educational Research Association, with experience serving on editorial boards and federal grant review panels.
Throughout this episode, we explore a range of fascinating topics, including:
1) How the philosophy and practice of The Wellness Way differ from both conventional and functional medicine.
2) How Dr. Flynn's approach goes beyond the typical chiropractic focus on spinal realignment to embrace holistic health restoration.
3) The essential elements of his medical philosophy, including the role of medications, supplements, and traditional treatments.
What I found most compelling about our conversation is how, despite holding some differing political viewpoints, we were able to engage in a thought-provoking discussion. Together, we highlight the importance of shifting from a reactive "disease model" to one that empowers patients to proactively improve their health and prevent illness.
We hope you enjoy this episode!

Nov 11, 2024 • 1h 11min
Microbiome, Personalized Nutrition and Longevity with Tim Spector, MD | MGC Ep. 79
In this episode of the Mind Gut Conversation podcast, I sit down with Dr. Tim Spector, an internationally renowned expert in microbiome science and personalized nutrition, as well as an acclaimed author.
He is a professor of genetic epidemiology at King’s College London and honorary consultant physician at Guy’s and St. Thomas’ National Health System Foundation
Trust.
He founded TwinsUK in 1992, one of the richest collections of clinical data in the world. He is the lead researcher behind the world’s biggest citizen science health project – the Covid Symptom Study app, and is the scientific co-founder of the company ZOE.
Throughout his career, Dr. Spector has received many awards and prizes, and is a Fellow of the Royal Society of Biology and the Academy of Medical Sciences. He has published over 900 scientific papers and is ranked by Google as being in the top 100 most cited scientists in the world.
In addition to his scientific publications, he has published four popular books, including the best-selling Diet Myth, Spoon-Fed, and more recently Food for Life – a Sunday Times bestseller.
During this episode, we talk about a wide range of topics, including precision nutrition, gut health and longevity. Some key questions & topics we discuss are:
• What is precision nutrition, and why do we need it?
• Gut microbes and metabolic health
• Does gut health play a causative role in longevity?
• What is ZOE, and what can ZOE do for me?
We hope you enjoy the episode!
To learn more, check out the ZOE Science & Nutrition podcast here: https://podcasts.apple.com/us/podcast/zoe-science-nutrition/id1611216298

Oct 28, 2024 • 53min
The Science Behind Healthy Aging with Eric Verdin, MD | MGC Ep. 78
In this episode of the Mind Gut Conversation podcast, I speak with Dr. Eric Verdin, one of the world’s experts on healthy aging and longevity. Dr. Verdin is president and CEO of the Buck Institute for Research of Aging, the world’s only research institution singularly focused on the biology of aging.
During this episode, we talk about a number of fascinating topics, including:
1) Besides lifestyle modifications, what are the most promising strategies to increase the health span in humans?
2) What is the reason for the progressive increase in centenarians in different parts of the world?
3) What role do genes play in longevity?
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9 snips
Sep 29, 2024 • 1h 1min
Can You Trust Your Gut? with Gerd Gigerenzer, PhD | MGC Ep. 77
In this engaging discussion, Dr. Gerd Gigerenzer, a leading expert in intuition and decision-making, shares his insights from the Max Planck Institute for Human Development. He dives into the differences between rational and intuitive decisions and questions whether women have a natural advantage in intuitive reasoning. The conversation explores how context influences these types of decisions and how AI measures up against human intuition. Gigerenzer emphasizes the importance of simple heuristics and the potential pitfalls of over-relying on complex analytics.

Sep 8, 2024 • 47min
Targeting the Brain in Gut-Brain Disorders with Laurie Keefer, PhD | MGC Ep. 76
In this episode of the MGC podcast, I speak with Dr. Laurie Keefer, a Health Psychologist and Professor of Medicine and Psychiatry at the Icahn School of Medicine at Mount Sinai in New York City.
Dr Keefer’s scientific contributions include the development and implementation of self-management and behavioral intervention tools, known as brain-gut behavior therapies for conditions such as Crohn’s disease, ulcerative colitis, IBS and gastroesophageal reflux disease.
Dr. Keefer is Founder and Chair of the Rome Foundation’s international GastroPsych organization and serves on the Board of Directors of the Rome Foundation. She has more than 250 peer-reviewed publications and is a sought-after speaker, mentor and collaborator.
Among several other topics, we talk about:
1) The importance of brain gut behavior therapies in inflammatory and functional GI disorders.
2) The long term resistance of the medical community to accept such non pharmacological therapies.
3) How she decides which behavioral approach to chose for individual patients.

Sep 2, 2024 • 53min
Tropical Bird Courtship: Insights Into Sex Hormones & The Brain with Barney Schlinger, PhD | MGC Ep. 75
In this episode of the Mind Gut Conversation podcast, I talk to Dr. Barney Schlinger, a passionate naturalist, incredible scientist and author of the recently published book, The Wingsnapppers: Lessons from an exuberant tropical bird.
Dr. Schlinger is a Professor in the Departments of Integrative Biology and Physiology, in the Department of Ecology, Evolution and Behavior and holds several prestigious positions at UCLA.
He has been funded by the National Institutes of Health and the National Science Foundation for over 30 years and is the author of nearly 190 peer reviewed scientific articles in high impact journals.
During this episode, we talk about the fascinating story behind the unique courtship of tropical birds, including the unexpected roles of: diet, sex hormones, the digestive system and the brain, that lead to this fascinating behavior.

Aug 17, 2024 • 43min
How The Microbiome Influences Our Risk of Viral Infections with Jennifer Fulcher, MD PhD | MGC Ep. 74
In this episode of The Mind Gut Conversation, I speak with Dr. Jennifer Fulcher, an Associate Professor in the Department of Medicine, Division of Infectious Diseases at UCLA, and a rising star in the Goodman Luskin Microbiome Center at UCLA.
Her research is supported by the National Institute of Allergy and Infectious Diseases, National Institute on Drug Abuse, the Doris Duke Foundation, and the California HIV Research Program. Her current research focuses on the effects of HIV and substance use on the gut and oral microbiomes.
In our conversation, we addresses some intriguing questions, including:
1) Does the gut microbiome play a role in resilience and resistance to viral infections?
2) Does gut dysbiosis and inflammatory blood markers precede HIV infection?
3) What is the role of the microbiome in susceptibility and severity of COVID-19?

Aug 2, 2024 • 52min
A New Understanding of Alzheimer's Disease with Rima Kaddurah-Daouk, MD | MGC Ep. 73
In this episode of The Mind Gut Conversation, I speak with Dr. Rima Kaddurah-Daouk, Professor in the Departments of Medicine and Psychiatry at Duke University Medical School and internationally recognized thought-leader in the pathophysiology of Alzheimer disease.
Dr. Kaddurah currently leads and coordinates an international multi-center research consortium, the Alzheimer’s Disease Metabolomics Consortium or ADMC which consists of more than 120 scientists from over 30 academic institutions.
She has published over 140 peer reviewed scientific publications, leads a large number of active NIH grants and in 2018, she ranked as the highest funded researcher in departments of psychiatry nationally. Dr. Kaddurah has more than 60 patents or patent applications on use of metabolomics for the diagnosis and treatment of brain diseases.
Topics we discuss in this podcast include:
1) What are the major scientific breakthroughs in our understanding of AD that have come from the ongoing research of the NIH AD consortium?
2) The scientific approach on which the AD grant is based on is radically different from the classical reductionistic biomedical research strategy and is based on systems biology and the paradigm of interconnectedness. Based on the lack of progress in effective treatments for AD to date, do you believe this new approach has a better chance of success?
3) Are there any new therapeutic strategies emerging from this new research?

Jul 14, 2024 • 43min
Cancer and the Healing Process with Wayne Jonas, MD | MGC Ep. 72
In this episode of the MGC podcast, I talk to Dr. Wayne Jonas, a pioneer and world-renowned in integrative health and healthcare delivery. Dr. Jonas is President of the Healing Works Foundation, whose mission is to make whole person, integrative care regular and routine.
He has published two paradigm-challenging books: How Healing Works: Get Well and Stay Well Using Your Hidden Power to Heal; and together with Dr. Alyssa McManamon, his most recent book: Healing and Cancer - a must read for anybody involved in the care of cancer patients.
In this episode, we discuss a wide range of topics including:
The purpose of Dr. Jonas' latest book, bringing the concepts of healing and whole person care further into oncology and healthcare so that people diagnosed with cancer feel better and live longer.
Current cancer care focuses on killing the cancer cell, and in the process supports a major industry to do that more effectively. However, killing cancer cells isn’t the whole story.
According to the concept of salutogenesis, when all systems are working well, a person with cancer can actively heal. Like a computer program running in the background, healing of the person is a process occurring all the time.

Jun 24, 2024 • 44min
The Future of Microbiome Testing with Joël Doré, PhD | MGC Ep. 71
In this episode of the Mind Gut Conversation podcast, I speak to professor Joel Dore, an internationally known expert on the gut microbiome and Research Director at the French National Research Institute for Agriculture, Food and Environment, INRAE.
Joel’s main research interest is the molecular assessment of the human intestinal microbiota in health and disease and investigation of the molecular cross-talk between intestinal bacteria and human cells. He has published more than 220 publications in peer reviewed scientific journals.
We discuss a wide range of topics, including the following questions:
1. Utility of currently available stool microbiome tests.
2. Are the unique characteristics of the gut microbiome adaptions to a rapidly changing environment including diet, medications, environmental chemicals like forever chemical, microplastics, other xenobiotics, causing a mismatch with our very slowly changing innate immune system which isn’t able to keep up?
3. Is there solid evidence to say that gut microbial diversity and richness plays a role in resilience to several diseases?
4. What are the major clinical applications of microbiome science?
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