Eagle's Eye View: Your Weekly CV Update From ACC.org

Discover the latest advancements in transseptal mitral valve-in-valve procedures, showcasing impressive outcomes from recent studies. Dive into the debate over complete versus culprit-only revascularization methods for older patients facing myocardial infarction. Plus, explore the intriguing connections between hypertensive pregnancy and heightened risks of coronary artery disease in women. This insightful discussion brings together cutting-edge cardiovascular research and important implications for patient care.

Discover the latest on TAVR's surprising outcomes in younger patients with comorbidities. Delve into the showdown between atorvastatin and rosuvastatin, revealing potential advantages for cardiovascular health. Finally, learn about a large trial that looked at how cutting down sedentary time might impact blood pressure in desk workers but found no significant changes. Tune in for intriguing insights from the world of cardiovascular health!

This week, the discussion centers around groundbreaking clinical trials from the recent TCT conference. The EARLY TAVR trial compares TAVR options versus clinical surveillance for aortic stenosis. Insights into the TRISCEND II trial reveal innovations for treating severe tricuspid regurgitation. The ECLIPSE study examines the benefits of orbital atherectomy before PCI. Finally, the CLEAR SYNERGY trial investigates colchicine effects post-PCI for STEMI patients. These trials are set to reshape cardiovascular treatment approaches.

In this week's View, Dr. Eagle looks at the consequences of discontinuing long-term drug treatment in patients with heart failure and reduced ejection fraction (HFrEF). He then explores the effect of race and sacubitril/valsartan use in HF patients documented in a pooled analysis of the PARADIGM-HF and PARAGON-HF trials. Finally, Dr. Eagle discusses the utility of systolic blood pressure (BP) polygenic risk scores and the treatment response in people with hypertension. Subscribe to Eagle's Eye View

In this week's View, Dr. Eagle looks at anthracycline cardiotoxicity in treatment of cancer patients. He then explores a scientific statement from the American Heart Association on cardiac arrhythmias and autonomic dysfunction associated with COVID-19. Finally, Dr. Eagle discusses the SWEDEHEART registry and intensive early and sustained lowering of non–HDL cholesterol after MI and prognosis. Subscribe to Eagle's Eye View

In this week's View, Dr. Eagle looks at an individual patient data meta-analysis of semaglutide and blood pressure (BP). He then explores an analysis from COMBINE-AF on heart failure (HF) risk assessment using biomarkers in patients with atrial fibrillation. Finally, Dr. Eagle discusses short-term dual antiplatelet therapy (DAPT) after drug-eluting stenting in patients with acute coronary syndrome (ACS). Subscribe to Eagle's Eye View

Discover the impact of COVID vaccination on cardiovascular events, highlighted by a study of over 8 million patients showing reduced risks. Delve into the long-term effects of septal reduction therapy in obstructive hypertrophic cardiomyopathy. Finally, compare varying clinical practice guidelines for managing acute pulmonary embolism. Tune in for a blend of cutting-edge research and practical insights!

In this week's View, Dr. Eagle looks at sex-specific differences in alive hospital discharge following abdominal aortic aneurysm (AAA) repair. He then explores how diffuse interstitial fibrosis of the myocardium predicts outcomes in moderate and asymptomatic severe aortic stenosis. Finally, Dr. Eagle discusses the value of mineralocorticoid receptor antagonists (MRAs) in heart failure (HF). Subscribe to Eagle's Eye View

In this week's View, Dr. Eagle looks at risk stratification in nonischemic dilated cardiomyopathy using CMR imaging. He then discusses the recent update of the Guideline for Perioperative CV Management for Noncardiac Surgery. Finally, Dr. Eagle talks about a review article on lipoprotein(a) and CVD. Subscribe to Eagle's Eye View

This discussion dives into long-term outcomes for patients with recurrent pericarditis and how machine learning is reshaping predictions. It also highlights the promising role of polygenic risk scores in assessing cardiovascular disease risk. Furthermore, the management of aortic disease in children with FBN1-related Marfan syndrome is examined, emphasizing personalized imaging strategies and treatment plans to improve health outcomes. Complex yet crucial topics come together to shed light on advancing cardiovascular care.