Anesthesiology Journal's podcast

Douglas Colquhoun, an Assistant Professor at the University of Michigan Medical School, shares insights on Patient Blood Management (PBM) during surgery. He discusses how rigorous adherence to PBM guidelines can significantly reduce postoperative complications, particularly in hip and knee arthroplasties. The conversation touches on the link between effective PBM practices and lower rates of major cardiac events, as well as the challenges of integrating these protocols into healthcare systems. Cost-effectiveness in PBM techniques is also explored, prompting a reevaluation of surgical practices.

Moderator: BobbieJean Sweitzer, M.D. Participants: Jessica R Ansari, M.D., M.S. and Craig M. Palmer, M.D. Articles Discussed: Uterine Tone Numeric Rating Score as an Early Indicator of Major Postpartum Hemorrhage During Cesarean Delivery: A Prospective Observational Study Predicting the Unpredictable: A New Approach to Predict Postpartum Hemorrhage from Uterine Atony Transcript

Creator: James P. Rathmell, M.D. July 2025, Volume 143, Issue 1 Overview of July issue original studies. Transcript

Moderator: James P. Rathmell, M.D. Participants: Carmen Bozic, M.D. Articles Discussed: Suzetrigine, a Nonopioid NaV1.8 Inhibitor for Treatment of Moderate-to-severe Acute Pain: Two Phase 3 Randomized Clinical Trials Suzetrigine: First in a New Class of Nonopioid Analgesics for Acute Pain Transcript

Moderator: James P. Rathmell, M.D. Participants: Rebecca L. Wu, M.D. and Max B. Kelz, M.D., Ph.D. Articles Discussed: TAK-925 (danavorexton), an Orexin Receptor 2 Agonist, Reduces Opioid-Induced Respiratory Depression and Sedation Without Affecting Analgesia in Healthy Adult Males Alluring Potential to Accelerate Emergence and Ameliorate Opioid-induced Respiratory Depression without Antagonizing Analgesia: Danavorexton Enters the Anesthetic Landscape Transcript

Moderator: BobbieJean, M.D. Participants: Douglas Colquhoun, M.B., M.Sc., M.P.H. and Stephan R. Thilen Articles Discussed: Neuromuscular Blockade and Antagonism in Patients with Renal Impairment: A Multicenter Retrospective Cross Sectional Study On and Off Label Use of Sugammadex in Patients with Renal Impairment in the 6 ½ Years Following FDA Approval Transcript

Creator: James P. Rathmell, M.D., M.B.A. June 2025, Volume 142, Issue 6 Overview of June issue original studies. Transcript

Moderator: BobbieJean Sweitzer, M.D. Participants: Daqing Ma, Ph.D. and Kate Leslie, M.B.B.S., M.D. Articles Discussed: Pyridoxine Prevents Postoperative Nausea and Vomiting in Gynecologic Laparoscopic Surgery: A Double-blind Randomized Controlled Trial B6 or Be Sick? Pyridoxine to Prevent Postoperative Nausea and Vomiting Transcript

Moderator: BobbieJean Sweitzer, M.D. Participants: Alessandro Belletti, M.D., and Samuel N. Heyman, M.D. Articles Discussed: Amino Acid Infusion for Kidney Protection in Cardiac Surgery Patients with Chronic Kidney Disease: A Secondary Analysis of the PROTECTION Trial Amino Acid Infusion for the Prevention of Acute Kidney Injury: Yet a Debatable Issue Transcript

Moderator: James P. Rathmell, M.D. Participants: Christopher Connor, M.D., Ph.D. and Peter John Schuller, M.B.B.S., B.Sc. Articles Discussed: Developing an EEG-based model to predict awakening after cardiac arrest using partial processing with the BIS Engine Unlocking Prognostic Potential in the Postarrest Electroencephalogram Transcript