

Riskgaming
Lux Capital
A podcast by venture capital firm Lux Capital on the opportunities and risks of science, technology, finance and the human condition. Hosted by Danny Crichton from our New York City studios.
Episodes
Mentioned books

7 snips
May 14, 2022 • 18min
Risk, Bias and Decision Making: Pre-mortems
Recently at Lux in New York City, Josh Wolfe invited three celebrated decision and risk specialists for a lunch to discuss the latest academic research and empirical insights from the world of psychology and decision sciences. Our lunch included Daniel Kahneman, who won the 2002 Nobel Prize in Economics for his work on decision sciences. His book Thinking Fast and Slow has been a major bestseller and summarizes much of his work in the field. We also had Annie Duke, a World Series of Poker champion who researches cognitive psychology at the University of Pennsylvania. Her books How to Decide and Thinking in Bets have also been tremendously influential best sellers, and she is also the co-founder of the Alliance for Decision Education. Also joining us was Michael Mauboussin, the Head of Consilient Research at Counterpoint Global and who has also taught finance for decades at Columbia. His book More Than You Know is similarly a major bestseller.
This is an edited four-part series from our lunch seminar, with each part covering one topic of the conversation for easier listening.
In this first part, we discuss the concept of pre-mortems, an approach of looking at the outcome of our decision and if it were to fail, why we think it would fail. It’s an approach that’s designed to overcome groupthink and avoid the fact that pessimists are really unpopular in group decision-making sessions. However, recent research has shown that they don’t always help people and groups change their mind. We look at pre-mortems, prospective hindsight, legitimizing dissent, self-serving bias and pre-parade or backcasts to see how this tool can affect and improve decision-making given the most recent academic literature.

May 14, 2022 • 9min
Risk, Bias and Decision Making: People never change their minds
Recently at Lux in New York City, Josh Wolfe invited three celebrated decision and risk specialists for a lunch to discuss the latest academic research and empirical insights from the world of psychology and decision sciences. Our lunch included Danny Kahneman, who won the 2002 Nobel Prize in Economics for his work on decision sciences. His book Thinking Fast and Slow has been a major bestseller and summarizes much of his work in the field. We also had Annie Duke, a World Series of Poker champion who researches cognitive psychology at the University of Pennsylvania. Her books How to Decide and Thinking in Bets have also been tremendously influential best sellers, and she is also the co-founder of the Alliance for Decision Education. Also joining us was Michael Mauboussin, the Head of Consilient Research at Counterpoint Global and who has also taught finance for decades at Columbia. His book More Than You Know is similarly a major bestseller.
In part two of our risk, bias and decision making lunch, Danny Kahneman, Annie Duke and Josh Wolfe discuss whether people change their minds, particularly on subjects that matter, why people care about dissonance reduction, and what circumstances lead people to changing their minds at all.

9 snips
May 14, 2022 • 22min
Risk, Bias and Decision Making: Defying the odds
Recently at Lux in New York City, Josh Wolfe invited three celebrated decision and risk specialists for a lunch to discuss the latest academic research and empirical insights from the world of psychology and decision sciences. Our lunch included Danny Kahneman, who won the 2002 Nobel Prize in Economics for his work on decision sciences. His book Thinking Fast and Slow has been a major bestseller and summarizes much of his work in the field. We also had Annie Duke, a World Series of Poker champion who researches cognitive psychology at the University of Pennsylvania. Her books How to Decide and Thinking in Bets have also been tremendously influential best sellers, and she is also the co-founder of the Alliance for Decision Education. Also joining us was Michael Mauboussin, the Head of Consilient Research at Counterpoint Global and who has also taught finance for decades at Columbia. His book More Than You Know is similarly a major bestseller.
In part three of our risk, bias and decision making lunch, Annie Duke, Michael Mauboussin, Danny Kahneman, and Josh Wolfe discuss optimism, base rates, overcoming negative expected values, population versus individual risks, calibrating risk assessments, and infectious amplification of optimism within groups.

May 14, 2022 • 7min
Risk, Bias and Decision Making: Hot hands
Recently at Lux in New York City, Josh Wolfe invited three celebrated decision and risk specialists for a lunch to discuss the latest academic research and empirical insights from the world of psychology and decision sciences. Our lunch included Danny Kahneman, who won the 2002 Nobel Prize in Economics for his work on decision sciences. His book Thinking Fast and Slow has been a major bestseller and summarizes much of his work in the field. We also had Annie Duke, a World Series of Poker champion who researches cognitive psychology at the University of Pennsylvania. Her books How to Decide and Thinking in Bets have also been tremendously influential best sellers, and she is also the co-founder of the Alliance for Decision Education. Also joining us was Michael Mauboussin, the Head of Consilient Research at Counterpoint Global and who has also taught finance for decades at Columbia. His book More Than You Know is similarly a major bestseller.
In the fourth and final segment of our risk, bias and decision making lunch, Josh Wolfe, Annie Duke, Danny Kahneman and Michael Mauboussin discuss the phenomenon of the so-called “hot hand,” the idea that a basketball player or an investor can have a streak of good luck that allows them to actually increase the odds of success on their future plays.

May 7, 2022 • 34min
Shredding the endowment investing playbook w/Scott Wilson, CIO of Washington University in St. Louis
University endowments are one of the key nexuses by which finance influences the future of science, tech, and the human condition, and what happens at endowments and other limited partners (LPs) matters deeply both for their clients but also the wider VC asset class. Washington University in St. Louis Chief Investment Officer Scott Wilson, who drove the university’s record-breaking 65% return last year and is also a Lux LP, joins the podcast to discuss how he redeemed $3.6 billion in assets his first week on the job in 2017, his origin story in rural Alaska, and WashU’s strategy of direct investing alongside its GPs. We then also discuss the global macro environment, crypto markets, the future of healthcare investing, as well as some book recommendations.

Apr 30, 2022 • 15min
The future of biotech is moving from bench to beach
While a huge amount of attention is being directed at crypto and media these days, one of the most important wild card investment trends of the 2020s is the coming expansion of biotech. Democratized science tools, improved research networking, and lab automation will revolutionize the practice of biotech, and that means there are huge opportunities for intrepid founders. But there’s a catch: biotech stock performance has been abysmal the past year, and many investors are walking away from the market. Josh Wolfe joins Danny Crichton to talk about what the gyrations in the biotech markets means for startups, some developments around the Human Genome Project, and what strategies existing biotech firms can take to weather the coming consolidation and reinvention of the industry.

Apr 23, 2022 • 18min
Chip demand and the future of the climate with Mythic AI’s Mike Henry
There’s a huge expansion in demand for compute power going on, with AI models, cryptocurrencies, autonomous vehicles and our social media algorithms all guzzling more chip cycles than ever before. But we’re also in the midst of a climate emergency, and chips are a major cause of energy demand. How do we reconcile the two? Joining me to talk about this as well as the future of the semiconductor industry, the CHIPS act, and other national industrial policies is Lux’s Shahin Farshchi and Mythic AI CEO and founder Mike Henry.

Apr 16, 2022 • 15min
Redlines for diplomacy and business with former USSOCOM commander Tony “T2” Thomas
“Redlines” in war are meant to be objective and unambiguous tests for a country to respond to another nation’s action. If one country uses chemical weapons in a conflict, that might violate the redline of another country and therefore force it to conduct military operations in response to reinforce the international laws and norms against the use of such weapons. Redlines though are often ambiguous, used poorly, and their deterrence effect is often diminished by a lack of credibility. How should leaders — from politicians to entrepreneurs — think about redlines? To answer that, host Danny Crichton was joined by Josh Wolfe and General Tony “T2” Thomas, the 11th Commander of U.S. Special Operations Command (USSOCOM) and venture partner at Lux Capital, to talk all things redlines from a hotel lobby in sunny Miami.

Apr 9, 2022 • 26min
The VC Power Law with CFR senior fellow Sebastian Mallaby
In his new book, “The Power Law: Venture Capital and the Making of the Future,” Council on Foreign Relations senior fellow Sebastian Mallaby brings his erudite attention from the hedge fund world to venture capital, interviewing the industry’s leading players over the last 50 years to discover what is unique about this industry that “manufactures courage.” In this episode, Mallaby, Josh Wolfe and Danny Crichton talk about the structural and cultural differences between hedge funds and VC firms, the long-term lessons that get re-learned by each generation of VCs, how succession is planned (and not), as well as a side story of a VC and a pile of maggot-filled meat laid by Hunter S. Thompson.

Apr 5, 2022 • 13min
Is web3 really just looking for Web 2.5?
web3 technologies have received prodigious funding the past two years as founders and VCs collectively search for the path to the next evolution of the internet. But how do we bridge the gap between the ubiquitous Web 2.0 world with what we see coming in web3? In this episode, Lux VC investor Grace Isford joins host Danny Crichton to discuss the key infrastructure investments in what she is dubbing “web2.5,” the crypto developer stack, and what’s next for crypto in 2022.