Neurology Minute

American Academy of Neurology
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Nov 6, 2025 • 4min

Neurotoxicity Imaging in Children and Young Adults After CAR T-Cell Therapy for B-Cell Malignancies

Dr. Alison Christy and Dr. Jennifer L. McGuire discuss neuroimaging findings linked to ICANS, exploring whether specific imaging patterns correlate with distinct neurologic symptoms. Show citation: McGuire JL, Pinto S, Erdogan EN, et al. Neuroimaging Findings in Children and Young Adults With Neurotoxicity After CAR T-Cell Therapy for B-Cell Malignancies. Neurology. 2025;105(7):e214086. doi:10.1212/WNL.0000000000214086
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Nov 6, 2025 • 4min

Neurotoxicity Imaging in Children and Young Adults After CAR T-Cell Therapy for B-Cell Malignancies

Dr. Alison Christy and Dr. Jennifer L. McGuire discuss neuroimaging findings linked to ICANS, exploring whether specific imaging patterns correlate with distinct neurologic symptoms. Show citation: McGuire JL, Pinto S, Erdogan EN, et al. Neuroimaging Findings in Children and Young Adults With Neurotoxicity After CAR T-Cell Therapy for B-Cell Malignancies. Neurology. 2025;105(7):e214086. doi:10.1212/WNL.0000000000214086
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Nov 5, 2025 • 4min

Optic Nerve Inclusion in the 2024 McDonald Criteria Revisions – Part 3

In the final episode of this three-part series, Dr. Jeff Lambe addresses practical considerations surrounding the inclusion of the optic nerve as a topography for demonstrating dissemination in space. Show citation: Montalban X, Lebrun-Frénay C, Oh J, et al. Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria. Lancet Neurol. 2025;24(10):850-865. doi:10.1016/S1474-4422(25)00270-4
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Nov 4, 2025 • 4min

Optic Nerve Inclusion in the 2024 McDonald Criteria Revisions – Part 2

In part two of this three-part series, Dr. Jeff Lambe outlines how the optic nerve is being incorporated as one of five topographies used to demonstrate dissemination in space. Show citation: Montalban X, Lebrun-Frénay C, Oh J, et al. Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria. Lancet Neurol. 2025;24(10):850-865. doi:10.1016/S1474-4422(25)00270-4
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Nov 3, 2025 • 3min

Optic Nerve Inclusion in the 2024 McDonald Criteria Revisions – Part 1

In part one of this three-part series, Dr. Jeff Lambe discusses the rationale for including the optic nerve in the 2024 revisions to the McDonald criteria. Show citation: Montalban X, Lebrun-Frénay C, Oh J, et al. Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria. Lancet Neurol. 2025;24(10):850-865. doi:10.1016/S1474-4422(25)00270-4
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Oct 31, 2025 • 3min

Persistent Postictal Central Apnea in Focal Seizures

Dr. Katie Krulisky and Dr. Stefano Meletti discuss the incidence and characteristics of postictal central apnea in focal seizures. Show citation: Meletti S, Burani M, Ballerini A, et al. Persistent Postictal Central Apnea in Focal Seizures: Incidence, Features, and Imaging Findings. Neurology. 2025;105(4):e213856. doi:10.1212/WNL.0000000000213856
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Oct 30, 2025 • 1min

Association Between Consumption of Artificial Sweeteners With Cognitive Decline

Dr. Greg Cooper and Dr. Claudia Suemoto discuss the association between consumption of low- and no-calorie sweeteners and cognitive decline. Show citations: Gonçalves NG, Martinez-Steele E, Lotufo PA, et al. Association Between Consumption of Low- and No-Calorie Artificial Sweeteners and Cognitive Decline: An 8-Year Prospective Study. Neurology. 2025;105(7):e214023. doi:10.1212/WNL.0000000000214023
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Oct 29, 2025 • 2min

Oropouche Virus

Dr. Paul Crane discusses Oropouche virus and its neurologic complications.
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Oct 28, 2025 • 3min

Multiple Sclerosis Imaging Biomarkers - Part 2

In the second part of this two-part series, Dr. Kaitlyn Palmer explains how these biomarkers change our approach to diagnosing multiple sclerosis. Show reference: Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria. Montalban, Xavier, et al. The Lancet Neurology, Volume 24, Issue 10, 850 - 865
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Oct 27, 2025 • 3min

Multiple Sclerosis Imaging Biomarkers - Part 1

In part one of this two-part series, Dr. Kaitlyn Palmer discusses two new MRI biomarkers to increase diagnostic specificity for multiple sclerosis. Show reference: Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria. Montalban, Xavier, et al. The Lancet Neurology, Volume 24, Issue 10, 850 - 865

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