Actor Glenn Howerton talks about topics ranging from Liquid Death and alternative drinks, to Neutropics and the transient nature of existence. They discuss the allure of smoking cigarettes, the talented actor Jesse Plummins, movie preferences, unexpected encounters at hotels and resorts, vampires and acting, creating opportunities, cathartic release, benefits of nicotine gum, and the importance of authenticity in performances.

Topics discussed include tongue scraping and chemical-free personal care products, making up songs in the car, improving attitudes with humor, the difficulty of connecting and the concept of dandruff, nostalgic hair removal mishaps, future challenges, feeling stuffed, and a funny high, and a funny experience reading a chapter book for children.

Comedian Malik Elassal talks about masturbation rituals, interpretations of 'God is great', speculating about Mickey Mouse's pants, the impact of a teacher on pursuing acting, mortgaging the present and legacy, survival instincts vs. worrying, the power of asking for help, integrating practices for success, the simplicity and beauty of life, working with special needs kids, and the importance of rules and disciplines.

The hosts talk about the creative process, the power of the unconscious mind, love and fear, dealing with inner thoughts and emotions, prioritizing family, personal fulfillment, and frustrations with construction delays.

Comedian and actor Mike Birbiglia discusses his new special on Netflix, his friendship with the host, and the concept of a 'day off'. They also talk about their energy levels, a previous episode, staying overnight at someone's place, sleeping arrangements, and the challenges of fitting in beds. The conversation includes humorous discussions about giving up pornography, self-improvement, and therapy, performing comedy on Broadway versus in comedy clubs, and playful conversations about ramen noodles and impressions.

Ben Marshall, John Higgins, and Martin Herlihy of Please Don't Destroy join the host to discuss their work on SNL and their new movie. They also chat about touring, imposter syndrome, creating sketches, and the dynamics within a comedy group. They share their thoughts on ghosts and UFOs, entertainment on a plane, and the importance of breathing exercises and supplements.

Rabbi Mordecai Finley, a Rabbi, discusses various interesting topics including the official beverages of different religions, sacred geometry and symbol origins, the role of wisdom in spirituality and counseling, taming the monkey mind, the power of slogans, embracing honesty and darkness, reflections on a joke and the power of humor, exploring parenting, evil, and media influence on children, concerns about Teenage Mutant Ninja Turtles, the role of comedy and wisdom, handling flight cancellation and questioning the concept of airlines, perception, ontology, and the concept of United as a conscious being, and exploring the meaning of Mitzvah and the act of giving.

The hosts share funny stories, wisdom, and spirituality. They explore the sounds and sensations of being in the jungle and reflect on holidays and rituals. They discuss Liam Neeson's sausage fingers, Bobby's strong approach to spirituality, and a man's transformation from tough to humble. They talk about accepting and justifying feelings and feature sponsors such as ARMR and Blue Land. They also recount their scorpion bite experience at an environmentally conscious hotel.

Comedian Eddie Ifft talks about common misheard lyrics, conspiracy theories, genitalia, strange encounters, emasculation, admiration for action sports, changing landscape of comedy, film projects, lottery ticket conversations, becoming undeniable in the entertainment industry, benefits of colostrum, living in the present moment, childhood escape, backlash to political correctness, mind-reading device, pipe smoking, and comedy logic.

Pete and Val catch up and talk about anxiety, hair products, shopping for parents, letting their child watch Teenage Mutant Ninja Turtles, attending a talk by Rupert Spira, exploring his teachings, balancing enjoyment and spiritual goals, and returning to oneself and the nature of the self.