The Readout Loud

STAT
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Nov 3, 2022 • 30min

233: How the biotech revolution could come apart at the seams

Our colleague Matthew Herper joins us to discuss his thoughtful, personal story on how the biotech revolution that brought us genome editing, Covid-19 vaccines, and lifesaving medicines could run aground if humanity can't get out of its own way.
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Oct 27, 2022 • 23min

232: Anti-science at the polls, a biotech odd couple, & the stakes of the midterms

Our colleague Sarah Owermohle joins us to discuss how pandemic shutdowns, Covid-19 vaccines, and the prospect of arresting Anthony Fauci have become campaign rallying cries in midterm elections. We also discuss the latest news in the life sciences, including the potential effects of federal drug-price negotiation and the virtues of befriending Pharrell Williams.
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Oct 20, 2022 • 35min

231: BU's Covid tinkering, FDA on trial, & why it's hard to take drugs off the market

Lawyer and bioethicist ​​Holly Fernandez Lynch joins us to explain a watershed test of the FDA's authority to revoke drug approvals. And STAT's Helen Branswell calls in to discuss the headline-grabbing research at Boston University involving a lab-developed version of the virus that causes Covid-19.
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Oct 13, 2022 • 34min

230: BIO's messy transition, mRNA's future, & Biogen's next CEO

STAT Washington correspondent Rachel Cohrs joins us to explain the abrupt departure of the CEO of BIO, the lobbying group representing biotech on Capitol Hill, and its wider implications. We also discuss the latest news in the life sciences, including the future of mRNA, a promising startup closing its doors, and Biogen’s search for a new CEO.
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Oct 6, 2022 • 28min

229: Nobels for science, biotech dealmaking, & a friendly FTC

The newest Nobel laureates got their phone calls from Stockholm this week, and STAT science writer Megan Molteni joins us to explain their prize-winning work in medicine and chemistry. We also discuss the latest news in the life sciences, including the state of biotech dealmaking and the evolution of Amylyx Pharmaceuticals.
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Sep 29, 2022 • 36min

228: A surprise success in Alzheimer's and how FDA history seeded modern controversy

Lecanemab, a new Alzheimer's treatment from partners Biogen and Eisai, succeeded in a pivotal clinical trial, and we explain the surprising development and its sweeping implications. Then, oncologist Mikkael Sekeres joins us to talk about his new book, which is a history of the FDA and an insider’s look at one of the agency’s most contentious drug approval hearings.
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Sep 22, 2022 • 34min

227: Biden's Covid declaration, twilight of the SPAC, & genome editing 2.0

Heidi Tworek, a professor at the University of British Columbia and expert on public health communication, joins us to discuss President Biden's declaration that "the pandemic is over" and how leaders around the world are talking about Covid-19 as it enters its third year. We’ll also discuss the latest news in the life sciences, including the twilight of the SPAC boom, the coming evolution of genome editing, and the next big trial in Alzheimer’s disease.
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Sep 15, 2022 • 28min

226: Pharma's telehealth gold mine, the return of the biotech IPO, & a merger deferred

Our colleague Katie Palmer joins us to explain a burgeoning trend in pharmaceutical advertising that has health policy experts alarmed. We also discuss the White House's investment in biotech, a bellwether IPO, and the latest twist in the Merck-Seagen saga.
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Sep 8, 2022 • 33min

225: Illumina's $8 billion limbo, a new treatment for ALS, & Emirati biotech funding

Our colleague Matthew Herper joins us to discuss how Illumina, the biggest company in genomic sequencing, got into an $8 billion predicament. We also discuss a dramatic development for a new ALS treatment, the latest in cancer research, and a well-funded new player in biotech venture capital.
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Sep 1, 2022 • 35min

224: The anti-aging research boom, the Godfather of biotech, & the future of Biogen

Our colleague Megan Molteni joins us to explain the scientific discoveries, rampant hype, and Silicon Valley billions behind the burgeoning field of longevity research. Then, we discuss the remarkable career of Stelios Papadopoulos, the venerated Godfather of biotech who faces the daunting task of saving Biogen.

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