
The Pharm So Hard Emergency Medicine & Hospital Pharmacy Podcast
The Pharm So Hard Podcast is a show focused primarily on emergency medicine and hospital pharmacy related topics. Episodes range from 5-30 minutes depending on the topic and guest speakers. The goal is to disseminate information in bite-sized episodes from experts in the field of acute care and hospital pharmacy sub-specialties.
Latest episodes

Apr 4, 2025 • 28min
Episode 123. Unveiling SEMP: A New Era in Emergency Medicine Pharmacy
In this episode of The Pharm So Hard Podcast, host Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP, introduces the Society of Emergency Medicine Pharmacists (SEMP), a newly established organization dedicated to advancing the practice of emergency medicine pharmacy. Jimmy discusses SEMP's mission to optimize pharmacotherapeutic care in emergency departments through practice improvement, education, advocacy, research, and international collaboration. He highlights the importance of creating a unified global community for emergency medicine pharmacists and explores how SEMP aims to provide tailored support and resources for practitioners in this dynamic field. Tune in to learn how SEMP plans to shape the future of emergency medicine pharmacy and how you can get involved.

9 snips
Feb 26, 2025 • 27min
Episode 122. SGLT2 Inhibitors in the ICU - Are We Missing an Opportunity?
Daniella Abi Kheir, a critical care pharmacy resident and SGLT2 inhibitor expert, joins host Jimmy Pruitt to explore the revolutionary potential of these drugs in ICU settings. They discuss the DEFENDER trial, unveiling how SGLT2 inhibitors may prevent renal replacement therapy and enhance outcomes in sepsis. The duo addresses safety concerns, such as DKA, and emphasizes the need for healthcare professionals to rethink these agents' roles. Additionally, they highlight the multifaceted benefits of SGLT2 inhibitors beyond diabetes management.

Feb 5, 2025 • 11min
Episode 121. Journavix: A New Era in Non-Opioid Pain Management?
A groundbreaking non-opioid pain medication, Journavix, is celebrated as the first of its kind in over 20 years. Experts discuss its unique sodium channel blocking mechanism and analyze clinical trial data showcasing its efficacy and safety. They delve into potential side effects and drug interactions, emphasizing its significance for pain management in emergency settings. The conversation also highlights cost implications, accessibility challenges, and the medication's potential to mitigate addiction risks while providing effective pain relief.

Jan 29, 2025 • 11min
Episode 120. Ketamine for Benzodiazepine-Resistant Status Epilepticus – A Game-Changer?
Explore the groundbreaking use of ketamine as a rescue medication for benzodiazepine-resistant status epilepticus. This research highlights its rapid ability to terminate seizures, potentially revolutionizing emergency management protocols. Insightful discussions include safety, dosing, and practical applications in the emergency department. The episode underscores the importance of considering specific patient populations and the need for further research. Plus, there's excitement about an upcoming medical conference to expand on these findings.

Dec 8, 2024 • 36min
Episode 119. Cephalosporins for Pyelonephritis: Insights from the COPY-ED Study
Exploring the COPY-ED study reveals intriguing insights into using cephalosporins for outpatient pyelonephritis, challenging the reliance on fluoroquinolones. The discussion emphasizes the importance of antibiotic stewardship in an era of rising resistance. Additionally, there's excitement about the upcoming Empower Rx conference in Las Vegas, highlighting collaborative opportunities for emergency medicine pharmacists. Join the conversation about evolving treatment strategies and community engagement!

Oct 31, 2024 • 29min
Episode 118. Does Roc Rock and Succs Really Suck? Paralyzing Agents in RSI
Rosa Malloy-Post, a PGY3 emergency department resident specializing in emergency medicine, joins the conversation to tackle the hot debate over paralytic agents in rapid sequence intubation. They dive into the pros and cons of Succinylcholine and Rocuronium, examining their pharmacologic properties, onset, and duration. The discussion is rich with expert insights on patient safety, dosing strategies, and clinical implications. Tune in for a lively exchange that determines whether Roc truly rocks or if Succs really suck!

Aug 13, 2024 • 29min
Episode 117. Early Subcutaneous Basal Insulin in Mild to Moderate DKA: A Discussion with Tessa and Brian
Brian W. Gilbert, PharmD, MBA, FCCM, FNCS, BCCCP, and Tessa R. Cox, PharmD, BCCCP, are experts in emergency medicine and DKA management. They dive into their groundbreaking study on the early use of subcutaneous insulin in mild to moderate DKA, revealing no significant difference in hospital stays between early and later treatment. The duo also discusses updated diagnostic criteria, management strategies, and the potential benefits of long-acting insulin, emphasizing the need for enhanced care protocols in emergency settings.

Jul 15, 2024 • 42min
Episode 116. Writing and Living InteGREAT with Andrea Sikora, Anthony Hawkins, and Susan Smith
Andrea Sikora, a clinical associate professor at the University of Georgia, Anthony Hawkins, also a clinical associate professor, and Susan Smith, a faculty member at the same institution, discuss their collaborative journey of writing the book 'InteGREAT'. They share insights on team development and building relationships in healthcare. The trio highlights the importance of leveraging strengths and achieving alignment within clinical teams. They also reflect on the emotional challenges of collaboration and the impact their work has on optimizing healthcare practices.

May 7, 2024 • 22min
Episode 115. Impact of EM CPP-driven sepsis antibiotic interventions with Taylor Cason
Taylor Cason, a clinical emergency medicine pharmacist at Caromont Regional Medical Center, shares insights from groundbreaking research on sepsis management. They discuss how involving clinical pharmacy practitioners improved antibiotic selection from 57% to 86% and accelerated administration by 64 minutes. The conversation highlights collaborative efforts to enhance antibiotic stewardship and the evolving role of pharmacists in emergency care. Cason emphasizes the need for ongoing improvements in antibiotic selection for conditions like UTIs and intra-abdominal infections.

Apr 22, 2024 • 7min
Episode 114. PharmD Lit Highlight: Risk of Arrhythmia in post-resuscitative shock after OHCA with Epi vs Norepi
In this episode of the Pharm So Hard Podcast's PharmD Literature Highlight Series, host Jimmy Pruitt, PharmD, BCPS, BCCCP, BCEMP discusses the study "Risk of arrhythmia in post-resuscitative shock after out-of-hospital cardiac arrest with epinephrine versus norepinephrine" by Sarah Normand, Pharm.D., Courtney Matthews, Pharm.D., Caitlin S. Brown, Pharm.D., Alicia E. Mattson, Pharm.D., Kristin C. Mara, M.S., Fernanda Bellolio, M.D., M.S., and Erin D. Wieruszewski, Pharm.D.
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