The Doctor & The Nurse

On today’s episode of The David Nurse Show, cardiovascular researcher and pharmacist, Dr. James DiNicolantonio, sets the record straight on one of the most misunderstood nutrients—salt. Far from being the enemy, sodium is essential for performance, focus, energy, and cardiovascular health. During his conversation with David, James explains why most people are chronically under-consuming salt and how this impacts everything from fatigue to hormonal health. Together David and James explore how low salt levels can increase insulin resistance, stress hormones, and even cravings, creating a dangerous cycle that sabotages physical and mental performance. James also breaks down how proper sodium intake improves endurance, sleep, and stress resilience—and gives specific guidance on how to tailor salt intake based on your activity level and lifestyle. This episode is a must-listen for athletes, entrepreneurs, and anyone wanting to perform at their highest level. CHAPTERS: 00:00 Introduction to Dr. James DiNicolantonio 01:32 Why Salt Is Not the Enemy 03:45 The Real Science Behind Sodium and Blood Pressure 06:10 Hydration Myths That Hurt Performance 08:05 Signs of Salt Deficiency in High Performers 10:22 How Low Salt Increases Insulin and Stress Hormones 13:01 Optimizing Sodium for Energy and Focus 15:17 Best Forms of Salt and Electrolyte Supplements 18:00 How to Personalize Your Salt Intake 20:04 Final Takeaways on Salt, Health & Longevity Learn more about your ad choices. Visit megaphone.fm/adchoices

Visit https://ketone.com/DAVID for 30% OFF your subscription order PLUS receive a free gift with your second shipment—fun surprises like a free 6-pack, Ketone-IQ merch, and more! Celebrity trainer Don Saladino joins David Nurse for this raw, energizing conversation about what it really takes to build and sustain elite-level health and performance—physically and mentally. On today’s episode Don outlines why consistency is the single most overlooked and irreplaceable factor in transformation—revealing how he’s structured his training for over 30 years to avoid burnout, stay injury-free, and keep evolving. Together the two explore how Don’s approach has evolved from his early Equinox days to working with top-tier Hollywood clients, and why standards—not hacks—create real transformation. Don discusses resistance training as the “entrée” to fitness, how he integrates cardio for recovery and longevity, and why NSVs (non-scale victories) are a far more reliable progress marker than the number on the scale. Don also takes a firm stance on the influencer vs. coach debate—calling out the lack of real-world experience in the online fitness space—and shares why application trumps lab results when it comes to real change. Dr. Gabrielle Lyon joins David toward the end of the episode to break down intramuscular adipose tissue (IMAT) as a game-changing new health marker and how movement is essential for skeletal muscle quality. They also discuss the best ways to track nutrition for body composition, the psychology of standards, and what truly sustainable excellence looks like. No matter where you’re at in your fitness journey, this episode will challenge you to raise your standards, think deeper, and train with more purpose. CHAPTERS: 00:00 Don Saladino’s Relentless Consistency 03:00 40,000+ Sessions and What They Taught Him 06:45 Periodization, Recovery & Training Blocks 11:20 Real Coaches vs Influencers 13:40 The Science vs Application Debate 16:00 Tracking, Feel, and Nutrition Misconceptions 18:45 Metabolic Flexibility and Real RMR Gains 21:15 Training to Failure: What It Really Takes 23:00 Celebrity Coaching and Industry Experience 26:15 Why Standards > Motivation 28:45 NSVs and Sustainable Progress 31:00 Ozempic, Shortcuts, and Long-Term Costs 34:00 Gabrielle Lyon on iMAT and Muscle Health 38:00 Optimal Training Frequency & Recovery 42:00 Reframing Body Fat vs Muscle Quality 46:00 Standards as a Lifestyle Filter Learn more about your ad choices. Visit megaphone.fm/adchoices

Visit https://ketone.com/DAVID for 30% OFF your subscription order PLUS receive a free gift with your second shipment—fun surprises like a free 6-pack, Ketone-IQ merch, and more! Christian Drapeau, a leading expert in stem cell science, joins David Nurse to unpack the often misunderstood world of stem cells and how they are changing the game for health, healing, and longevity. Rather than splurging on expensive injections abroad, Christian outlines how specific plant extracts can trigger your own body to release millions of stem cells daily—jumpstarting recovery, rejuvenation, and regeneration from within. David and Christian’s conversation also navigates the socio-political resistance to stem cell technologies in Western countries, detailing how the pharmaceutical industry’s profit-driven model clashes with treatments that actually restore health rather than manage symptoms. Christian brings clarity to a cutting-edge yet practical health approach that many medical professionals still dismiss simply because it challenges the status quo. This episode is a must-listen for anyone looking to optimize performance, prevent disease, or better understand how to support the body’s natural healing abilities. CHAPTERS: 00:00 The Future of Medicine—Stem Cell Repair Potential 02:07 Why Stem Cells Are Misunderstood 03:00 Stem Cells as the Body’s Repair System 04:54 Regulatory Resistance and the Pharma Business Model 08:47 The Truth About Stemregen and Plant-Based Activation 10:32 From Lab to Reality: Proof of Heart Regeneration 12:33 How Much Stem Cell Release Is Possible? 14:58 Top 5 Plants That Mobilize Stem Cells 15:37 Study: Accelerated Injury Recovery in Elite Athletes 18:59 Microtrauma, Athletic Recovery & Injury Prevention 19:21 What is ESCM (Endogenous Stem Cell Mobilization)? 21:20 What It'll Take for Mainstream Acceptance 24:44 Why This Could Be a Turning Point in Modern Health 26:30 Stem Cells: From Concept to Cultural Acceptance Learn more about your ad choices. Visit megaphone.fm/adchoices

Visit https://ketone.com/DAVID for 30% OFF your subscription order PLUS receive a free gift with your second shipment—fun surprises like a free 6-pack, Ketone-IQ merch, and more! Dr. Latt Mansor’s path from a small town in Malaysia to earning degrees at Columbia and Oxford is a story of relentless curiosity, resilience, and timing. In this compelling conversation with David Nurse, Latt reveals how a series of unexpected decisions led him to the forefront of ketone research at H.V.M.N., where he now leads groundbreaking studies on performance, focus, recovery, and heart health. He breaks down the science behind ketones—why the brain and body love them, how Ketone IQ differs from traditional energy sources like caffeine, and what the data shows in real-world applications: improved endurance, sharper mental clarity, deeper sleep, and even enhanced cardiac output in heart failure patients. But this episode is about more than science. Latt shares how personal loss, cultural identity, and internal self-doubt shaped his mission to help others live longer, more optimized lives. It’s a conversation on fuel—not just for the body, but for the mind, purpose, and belief. Whether you’re training for peak performance, building a business, or simply aiming to think and feel your best, this episode delivers the clarity, consistency, and actionable insight you need to operate at your highest level—physically and mentally. CHAPTERS: 00:00 Latt's Journey: From Malaysia to Oxford 06:43 Breaking Into Biotech Without a Plan 12:59 The Startup Pivot: From Academia to Entrepreneurship 17:01 How Ketones Work in the Body 21:50 Ketone IQ vs. Caffeine: Real Energy Without the Crash 25:33 Sports Performance & Anaerobic Gains 30:20 Ketones for Mental Focus & Flow State 33:45 Sleep Enhancement & Ketones at Night 37:02 Appetite Suppression & Weight Control Studies 40:25 Heart Health Breakthroughs in Ketone Research 43:57 Risks, Cautions & What Ketones Can't Do 45:31 The Real Takeaway: Consistency, Self-Belief & Performance Optimization Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Chris Asandra, one of the top hormone and peptide therapy experts in the world, sits down with David Nurse to discuss the frontier of health optimization—and why it's not just about looking younger, but truly feeling better, longer. From testosterone therapy to breakthrough peptides like BPC-157, CJC-1295, and GHK copper, this conversation unpacks the real science behind the “Hollywood stacks” transforming how top performers—from actors to athletes—prepare their bodies and minds. Known as a leading expert in anti-aging and performance medicine, Dr. Asandra shares the truth about TRT, peptide stacks, Ozempic alternatives, and the secrets behind Hollywood’s physique transformations. The episode covers the stigma around hormone replacement, the power of copper peptides, and how hormone balancing is transforming both male and female lives. David and Chris also explore gene therapy trends, optimal supplement stacks, and what the future of personalized medicine looks like. Dr. Asandra pulls back the curtain on peptides that heal gut lining, stimulate growth hormone, burn fat, and even promote collagen and hair regrowth. The two also dive into Ozempic and its alternatives, the growing impact of GLP-1s, and how people are using these compounds safely to transform their health—with less risk and more reward than traditional pharmaceuticals. Whether you’re getting ready for a blockbuster role or just want to feel your best, Dr. Asandra maps out the exact protocols and stacks that get real results—and why working with a qualified professional matters more than ever. If you're curious about anti-aging, aesthetic performance, or the truth behind what top-level talent is using, this episode will open your eyes to a powerful new health paradigm. CHAPTERS: 00:00 Introduction to Dr. Chris Asandra 01:42 The Science and Stigma Behind Peptides 05:20 Ozempic, GLP-1s, and Safe Fat Loss 10:03 The Power of Copper Peptides 13:00 TRT: Truths, Myths, and Proper Use 17:50 Building the Ideal Stack: Lean vs. Mass Goals 23:15 Injectables vs. Orals: What's Safer? 26:45 Brian Johnson, Gene Therapy, and Follistatin 29:00 Hormone Therapy for Women: Pre and Post-Menopause 32:40 How to Work with Dr. Asandra 34:10 Final Thoughts on Changing Lives with Hormones Learn more about your ad choices. Visit megaphone.fm/adchoices

What if everything you thought you knew about nutrition, muscle, and longevity was outdated? In this high-impact conversation, David Nurse sits down with Dr. Gabrielle Lyon—founder of the Muscle-Centric Medicine® movement—to break the mold on traditional health thinking. From exposing the myths behind evidence-based medicine to unveiling the overlooked power of muscle in aging and disease prevention, this episode covers the cutting edge of metabolic health. You’ll hear insider insights on peptides like BPC-157, Ozempic vs. Manjaro, stem cell therapies, copper’s role in vitality, intramuscular adipose tissue (IMAT), and how discipline starts with standards—not motivation. Gabrielle also shares visionary takes on body composition, and what recovery will look like 10 years from now. If you're tired of the same recycled fitness advice and want real science, real stories, and real strategies from one of the sharpest minds in the field, this episode is your edge. 👉 Don’t forget to subscribe, share, and join the movement at davidnurse.com ---- CHAPTERS: 00:00 The Real Metric: Muscle Quality Over Body Fat 06:43 Ozempic, Manjurno & the Future of Weight Loss Drugs 12:20 Stem Cells, Peptides & What’s Actually Worth It 18:52 Copper, Iron, and Hormones: Micronutrient Talk 24:30 The Training Equation: Movement, Strength & Consistency 30:15 Standards, Discipline & The Power of Mission 36:20 Genetic Drive vs. Environment: Raising the Next Greats 42:18 Mortality, Hospice & Facing the End Well 47:35 Cancer, Heart Health & What Tests Actually Matter 52:18 Overconsumption, Processed Foods & Global Health Gaps 56:47 Reaching the Masses: From Protein to MrBeast Learn more about your ad choices. Visit megaphone.fm/adchoices

Dr. Anurag Singh, a leading expert in longevity and mitochondrial health, shares insights into the essential role of mitochondria as the powerhouses of our cells. He discusses how mitochondria evolved and their decline impacts aging. Dr. Singh reveals three strategies to enhance mitochondrial health: biogenesis, efficiency, and mitophagy. The conversation explores the benefits of certain supplements like resveratrol and urolithin A while highlighting the importance of diet, particularly the Mediterranean diet, and lifestyle choices in maintaining mitochondrial function.

What if there was a formula to tap into flow state more often and sustain it longer? Neuroscientist Rachel Lambert joins David for this special bonus episode of The Dr. & The Nurse, embarking on a mission to crack the code. Together they break down the science of flow, the role of brain waves, and why most people struggle to replicate their peak moments.During their conversation Rachel and David discuss why flow feels effortless yet remains elusive, touching on research from Mihály Csíkszentmihályi and Steven Kotler while revealing gaps in traditional flow science. David challenges existing theories, arguing that flow isn’t just about pushing limits—it’s about training the mind for adaptability.Listeners will also get an exclusive glimpse into the Flow Code Study, the first scientifically-backed approach to mapping flow in the brain. Rachel and David share insights on how neurofeedback, brainwave training, and mental conditioning can unlock higher performance in sports, business, and daily life.If you’ve ever wondered how to tap into your flow state on command, this super practical conversation lays the foundation for understanding and mastering flow state like never before.Follow Rachel on Instagram at @braincodecenters Timeline is offering 10% off your order of Mitopure this week only while supplies last: timeline.com/DAVIDNURSECHAPTERS:00:00 Intro – Breaking Down Flow State03:06 Defining Flow: A Personalized State of Peak Performance05:15 Understanding the Five Brain Waves08:09 The Role of Gamma in High-Level Cognition12:43 Building the Perfect Brainwave Cocktail for Flow14:29 Why Athletes Struggle to Replicate Flow State16:08 The Key to Training Your Brain for Peak Performance19:30 Neurofeedback & The Science of Brainwave Regulation21:12 How to Train Your Brain at Braincode Centers24:53 The Future of Flow Science & The Flow Code Study Learn more about your ad choices. Visit megaphone.fm/adchoices

David is joined by some top-tier guests for this special episode of The Dr. & The Nurse! First up, mixed martial artist Michael Chandler talks about the concept of embracing uncertainty in the ring—digging deep to tap into a state of flow no matter who he’s faced with. Next, David sits down with retired NBA player Gordon Hayward—Gordon taking the time to share a few of the groundbreaking insights he learned from his one-on-one coaching relationship with Kobe Bryant. Finally, David talks with George Mumford—Kobe and Michael Jordan’s mental coach—all about being a life-long learner. Each of these guests has so much wisdom to share, and you’re not going to want to miss a single minute! As always, David is joined by Dr. Daniel Amen towards the end of the episode to analyze what’s actually going on in the brains of these top athletes, performers, and coaches. Together David and Dr. Amen discuss if it’s possible to prepare for some of the high-pressure situations Michael, Gordon, and George described. The two also take a look at the factors that actually make these performers great—is it the number of wins versus loses, or simply a love for competition that drives them to be their best? Don’t miss this inspiring, impactful episode! Follow Michael Chandler on Instagram at @mikechandlermma Follow Gordon Hayward on Instagram at @gordonhayward Learn more about George Mumford and his practice on his website: https://georgemumford.com/. Timeline is offering 33% off your order of Mitopure this week only while supplies last: timeline.com/DAVIDNURSE33.CHAPTERS00:00 Introduction to High Performance and Mindfulness02:42 The Importance of Preparation and Flow State03:04 Michael Chandler Interview06:07 Lessons from Legends: Kobe Bryant and Michael Jordan08:22 Gordon Hayward Interview11:58 Overcoming Struggles and Expectations14:52 Navigating Social Media and External Opinions17:49 George Mumford Interview18:04 Embracing Flow and Creativity23:53 The Power of Preparation and Passion27:08 Dr. Daniel Amen's Thoughts30:01 The Love of Competition vs. Outcome Learn more about your ad choices. Visit megaphone.fm/adchoices

Ever struggle with refocusing during the day or recharging at night? Meet Muse, the newest innovation in meditation technology. Use my link for 20% off your purchase today: http://choosemuse.com/NURSE The flow state: that ever-elusive place where anything comes naturally—actions follow thoughts and everything works together in perfect harmony. How do we achieve that flow state to perform at our highest levels, or is that even possible? On today’s episode of The Dr. & The Nurse David sits down with acclaimed neuroscientist and the creator of Muse, Ariel Garten, to outline exactly how to attain that state of flow through optimized sleep, meditation, and visualization. David and Ariel begin their conversation by looking at some of the ways we can achieve flow state, from metavisualization—a combination of meditation and visualization—to stimulating pressure so we can perform better when the pressure is actually real. They then get into how optimizing sleep can help us perform to the best of our ability no matter what we’re trying to achieve. Ariel points to Muse—a tool she helped create—that acts as a data tracker for your brain and can also be used as a meditation tool to help you fall asleep, and stay asleep. The two wrap up their conversation by discussing how to de-regulate and up-regulate your brain for optimal performance. Dr. Daniel Amen joins David for the second part of the episode, weighing in on Ariel’s points about metavisualization and which levels of brain activity—if any—are ideal for achieving flow state. Learn more about Ariel and Muse here: https://choosemuse.com/. CHAPTERS00:00 Introduction to Flow and Meditation03:08 Understanding Flow State05:52 Brainwaves and Flow09:09 The Role of Meditation in Mental Health11:53 Meta Visualization and Its Impact15:11 Simulating Pressure in Performance18:07 The Importance of Sleep for Flow21:07 Introducing Muse: The Brain Sensing Headband23:53 Deep Sleep and Its Benefits26:46 Neurofeedback and Brainwave Training29:59 Practical Techniques for Up and Down Regulation32:53 Conclusion and Future of Flow State Training Learn more about your ad choices. Visit megaphone.fm/adchoices