Dr. Anastasia Bendebury and Dr. Michael Shilo DeLay discuss the role of belief in science, controversies in cosmology, and the scientific method. They explore the provisional nature of scientific facts, epistemic humility, and different ways to arrive at scientific truths. The podcast also delves into the Big Bang theory, the age of the universe, and the lack of scientific evidence supporting astrology.

Michael Saylor, American entrepreneur and business executive, discusses the physics of Bitcoin, its potential to replace the US dollar, and the challenges faced by traditional money. They explore the impact of software, the purpose of coin ridges, and the concept of wealth. The episode also touches on the growth of Bitcoin during the COVID-19 pandemic and the benefits of online learning.

Jim Al-Khalili, a theoretical physicist, discusses the connection between science and poetry, the scientific method variations, and the need to temper expectations in physics. They explore the relationship between knowledge and wisdom and the role of models in science, addressing concerns about politicians misusing the phrase 'follow the science'. They emphasize the importance of questioning scientific claims and highlight the sobering realization that there is still much more to understand in theoretical physics.

Chris Miller, industry expert in computer chips, discusses the unfolding race in chip development between the United States, Taiwan, and China. Topics include the history of semiconductors, challenges in chip manufacturing, importance of military funding, chip manufacturing and geopolitics, China's demographic and economic challenges, Bitcoin mining and energy efficiency.

Brian Keating, physics professor and host of the podcast, celebrates reaching 200K subscribers by answering questions from listeners. Topics discussed include resources for learning physics, access to free educational content on YouTube, the funding of the project, exploring future technologies and energy sources, the expansion rate of the universe, and a promotion for the Jordan Harbinger Show.

Mo Gawdat, founder of One Billion Happy and host of Slo Mo podcast, discusses AI, happiness, and intelligent design. They talk about book titles, AI safety, Google X's brilliance, creating digital avatars, loneliness, and religion. They also touch on emotions, mathematics as the coolest invention, and express gratitude and support.

Stephen Wolfram, computer scientist and physicist, discusses his groundbreaking discovery challenging the second law of thermodynamics. He explores the nature of time and temperature, delves into dark matter, and compares classical mechanics to quantum mechanics. Wolfram also addresses audience questions and discusses the future of science in the age of AI.

Astronomer and physicist Brian Keating hosts a podcast featuring astrobiologist Paul Davies and physicist Maulik Parikh. They discuss alternative theories challenging the Big Bang, the expansion rate of the universe, cosmic origins, and the BICEP experiment. They also explore the uncertainties and different views of the universe, progress in detectors for measuring the cosmic microwave background, bouncing models, pollution in the universe, and the search for B-modes signals. Additionally, they delve into subtracting foreground dust, examining the inflationary signal, and the concept of the multiverse. The podcast concludes with a discussion on the implications of the Big Bang and an ad for the Jordan Harbinger Show.

Nate Polson, the Canadian Prepper, discusses preparedness and living in a post-apocalyptic world. They explore why he stays prepared, the worth of a post-apocalyptic world, and the appreciation of what we have. They touch on balancing preparedness, resilience, and positivity.

Craig Venter, synthetic biologist, discusses the world of synthetic biology and engineering synthetic life. Topics covered include mapping the human genome, DNA durability and extraterrestrial life, dangers of synthetic biology, the next frontier for synthetic biology, and the race to sequence the human genome.