
The Generalist
“The future is already here. It’s just not evenly distributed.”
The Generalist Podcast brings you weekly conversations with the people who live in these pockets of the future – visionary founders, prescient investors, and original thinkers. Each episode is designed to introduce you to new ideas, technologies, and markets and help you prepare for the world of tomorrow.
Latest episodes

50 snips
May 20, 2025 • 1h 27min
How Anduril Is Reimagining the Defense Industry: Faster Tech, Ethical AI, and a New Kind of Deterrence | Trae Stephens (Co-Founder & Executive Chairman, Anduril)
Trae Stephens, co-founder and Executive Chairman of Anduril, shares insights on revolutionizing defense technology with a Silicon Valley approach. He discusses the ethical dilemmas of warfare and the necessity of innovation amidst rising global tensions, particularly with China. Trae highlights how Anduril's software, Lattice, enhances military capabilities and addresses traditional defense contract limitations. He reflects on Just War Theory, the importance of transparency in recruiting, and how his personal faith aligns with the company's mission for responsible technological advancement.

61 snips
May 6, 2025 • 1h 26min
The Substack Playbook: Inside The $650M Platform Rewriting Media, Trust, and Creator Economics | Chris Best & Hamish McKenzie (Co-Founders)
Chris Best and Hamish McKenzie, co-founders of Substack, discuss how their platform empowers independent writers through a subscription model that fosters a direct creator-audience connection. They explore the impact of AI on creativity and contrast their approach with traditional media, highlighting a pivotal clash with Elon Musk that ultimately strengthened their vision. The conversation covers the transformative potential of Substack for diverse content creators and addresses the changing economics of the media landscape.

106 snips
Apr 29, 2025 • 1h 21min
Lessons from 20 Years of Venture Capital: Roelof Botha (Managing Partner and Steward at Sequoia Capital)
Roelof Botha, Managing Partner at Sequoia Capital, shares insights from his 20 years of venture capital experience. He discusses the importance of long-term thinking and the psychological biases that hinder investors. Roelof highlights how excess funding can hamper innovation and recounts PayPal’s pivotal transformations born from challenges. He warns against the risks of the AI boom and emphasizes rational investment strategies. Additionally, he reflects on missed opportunities and the need for a disciplined approach to investment amidst market cycles.

62 snips
Apr 15, 2025 • 1h 27min
Shrinking the Gap Between Sci-Fi and Sci-Fact: Josh Wolfe (Co-Founder of Lux Capital)
Josh Wolfe, co-founder of Lux Capital, dives into futuristic innovations like genetically modified pig organs for transplantation and the groundbreaking technology allowing us to 'teleport' smells. He discusses how these advancements can reshape industries and even lead to life-saving medical solutions. Wolfe emphasizes the role of speculative risks in tech investments and shares insights on identifying market trends. Additionally, he explores the fascinating intersection of comic book lore with biotechnology, promising a thrilling glimpse into the future of science.

84 snips
Apr 8, 2025 • 1h 15min
How AI Will Enhance Human Potential, Not Replace It: Reid Hoffman
Reid Hoffman, co-founder of LinkedIn and AI pioneer, offers a hopeful perspective on AI's future in his recent discussion. He argues that rather than diminishing human agency, AI can enhance creativity and deepen friendships. Hoffman explores the philosophical implications of AI, including whether machines can truly think. He emphasizes the importance of balancing technology with human values and showcases how we can use AI to foster collaboration rather than passive consumption. His insights aim to reshape the narrative around technology and its role in human evolution.

Mar 31, 2025 • 2min
Introducing The Generalist Podcast
Welcome to The Generalist – a podcast about the future brought to you by Mario Gabriele. This isn’t your typical innovation podcast. Each week, we go beyond the headlines and into the minds of the founders, investors, and thinkers who are building tomorrow’s world. From AI to space exploration, nuclear fusion to new media, stablecoins to semiconductors, these are the people living in the future today.In just 60 minutes each episode, we’ll dive into the ideas, technologies, and strategies that are shaping industries and societies in real-time. Production and marketing by penname.co.