Empowered Patient Podcast

Dr. Aaron Koenig, Senior Medical Director and Mike Quirk, Vice President of pharmacology Sage Therapeutics focus on disorders of cognition and diseases that reflect determinants of impaired cognition such as Alzheimer's, Parkinson's and Huntington's. Their drug Sage-718, a novel mechanism of action, targets a protein in the brain, the NMDA receptor, thought to be the brain's coincidence detector designed to link together information that flows from different neural pathways and perhaps correct some of the symptoms causing functional impairment. @SageBiotech #Alzheimers #Parkinsons #Huntingtons #executivefunction #cognition #neurodegeneration SageRx.com Download the transcript here  

Dr. Travis Mickle President and CEO KemPharm describes the development of AZSTARYS, the stimulant-based methylphenidate prodrug treatment for ADHD one of the most common central nervous system diseases. This prodrug stimulates the norepinephrine dopamine reuptake inhibitor improving concentration, executive function, and irritability and provides for long-acting effect and protection from abuse as it is broken down in the lower GI. Travis' personal experience with ADHD and raising children with ADHD gives him a deep understanding of the challenges facing patients as well as their physicians. @kempharm #Kempharm $KMPH #ADHD #CNS KemPharm.com Download the transcript here.

Dr. Mark Allen, Co-Founder and CEO, Elevian is looking to disrupt the longevity business by developing a recombinant GDF11 to treat and prevent multiple age-related diseases. The first application being investigated is for stroke recovery drawing on the discovery that GDF11 decreases with age and when replenished, returns the brain to a healthier pattern of vascularization. Not looking to extend just the life span, the goal is to target the aging process and extend the healthy lifespan. @ElevianInc #aging #StrokeRecovery #AgeRelatedDisease #GDF11 Elevian.com Download the transcript here.

Dr. Steve Kanes, Chief Medical Officer, Sage Therapeutics takes the view that mental disorders and brain health disorders need to be treated like any other medicine. Driving this paradigm shift is the development of breakthrough zuranalone, an oral limited-time treatment to replace taking medicine chronically for those suffering from major depressive disorder. Clinical trials are showing when people do experience recurrences of MDD and episodes are treated when they occur, there are long and prolonged benefits. @SageBiotech #postpartum #depression #MajorDepressiveDisorder #MDD SageRx.com Download the transcript here.

Louis Martinez, Chief Information Officer, EHR Data shines a light on the decentralization of healthcare data collected by providers, insurance carriers, pharmacists and other medical service providers. With a goal of centralizing disparate health data and providing access at point of care, EHR is using blockchain to collect data globally to allow easy access for patients with an ability to grant permission for access to doctors and other health professionals. The pandemic is driving the need to reduce healthcare costs by eliminating redundant efforts and treatments not in the patient's best interest or long-term wellness and for patients to share data to address population health emergencies. #EHRData #myEHRstory  #Wavemaker #COVID19 #blockchain EHRData.com Download the transcript here  

Vu Truong, CEO, Aridis Pharmaceuticals is taking on the challenge of making an inhaled monoclonal antibody to treat COVID-19 to allow for the easier patient access.  Drawing on their work in infectious diseases and with a number of monoclonal antibodies candidates to treat bacteria infection associated with superbugs and antibiotic resistance, Aridis is  finding ways to overcome lack of usage of similar potent antibodies from Regeneron and Eli Lilly to combat the coronavirus. @Aridis_Pharma #AridisPharma #Aridis #Superbugs #AMR #InfectiousDisease #COVID19 #mAb #MonoclonalAntibody #immunotherapy #RespiratoryInfections #CoronavirusVariants AridisPharma.com Download the transcript here

Niloy Sanyal, Chief Marketing Officer, LeanTaaS is focused on the current state of the healthcare system in this wartime environment. In light of COVID-19 challenges particularly for those patients needing acute care, the need to optimize use of operating rooms, ICU beds, infusion chairs, and medical professionals requires more attention to improving capacity utilization.  Planning for a post pandemic peacetime era using AI tools will give patients quicker access to scarce capacity and drive up medical staff satisfaction. @LeanTaaS #LeanTaaS #COVID19 #DigitalHealth #HealthTech LeanTaaS.com Download the transcript here  

Mariya Pylypiv, Founder and Co-Chairwoman, UpHealth talks about empowering patients suffering from chronic conditions with a global comprehensive digital health technology and tech-enabled services platform. Working with care providers, health systems and payers, UpHealth is addressing the complex medical, behavioral, and social challenges of this fast-growing population with many unmet needs. The mission of UpHealth and their related companies is to provide high quality, affordable and accessible care to people around the world. @UpHealth #Thrasys #Glocal #SPAC #DigitalHealth #COVID19 #HumanizeHealthcare #BeTheChange #healthequity #digitaltransformation UpHealthinc.com Download the transcript here

Lynne Georgopoulos, VP Regulatory Strategy, Certara describes the company's platform to optimize pediatric drug development using biosimulation.  With an eye on pediatric diseases, Certara is employing modeling and simulation to determine how a drug developed for adults may be metabolized in children, including neonates. They are also operationalizing clinical trials to be more efficient and potentially less invasive which is important when working with young children. @certara #biosimulation #RACEforChildren #rarediseases #pediatriconcology Certara.com Download the transcript here

Dr. Romina Ghassemi, chiropractor and founder of Think Healthy is an expert on posture and is raising awareness about the need to address the health of the full spine along with solutions to address stress and related diseases. Her traditional business has been with the aging population to reduce pain and insure mobility. COVID-19 has increased the need to address the importance of good posture with more people working from home in make-shift arrangements as well as healthcare professionals dealing with long hours and burn-out.   #ThinkHealthy #COVID19 #stress #chiropractor ThinkHealthy.com  Download the transcript here