Empowered Patient Podcast

Ron Chiarello PhD, Founder, CEO and Chairman of the Board, Alveo Technologies talks about the need for a low-cost, easy-to-use diagnostic platform to allow more people to detect and manage an infectious disease like COVID-19. Winning the XPRIZE Rapid COVID-19 Testing Competition has highlighted their be.well diagnostic platform which uses an at-home system to take a nasal swab that gets placed in a disposable cartridge that goes into an analyzer that communicates to a mobile device with RNA-based test results in less than 30 minutes. #COVID19 #COVIDVaccine #COVIDTesting #InfectiousDisease #PublicHealth AlveoTechnologies.com Download the transcript here

Dr. R.J. Tesi, President and CEO, INmune Bio shines light on the complexity of the immune system by pointing out that while much work has been done on the adaptive immune system, the key to treating Alzheimer's might be to address the dysregulated innate immune system due to chronic inflammation. R.J. talks about developing XPro1595 a second generation selective TNF inhibitor which is designed to reduce inflammatory activity in the brain. They are also validating novel neuroimaging techniques and biomarkers to help predict which patients may respond to treating neuroinflammation as an underlying cause of their Alzheimer's. @INmuneBio #neuroinflammation #Alzheimers #cytokine #biotech #clinicaltrial #biomarkers #InnateImmuneSystem INmuneBio.com Download the transcript here  

Mary Guillermin, Director of Communications and Senior Pellin Practicioner at the Pellin Institute International and author talks about her book John Guillermin: The Man, The Myth, The Movies a story about her husband the British writer and film director of such films as King Kong, The Towering Inferno, The Blue Max and Rapture. Mary talks about her own experience dealing with depression, the need to understand the mood swings of those with bipolar disease particularly of those creatives types like John, and why we need to destigmatize mental health care.   #WildMan #MentalHealth #MentalHealthAwareness #BiPolarAwareness #Worldbipolarday #OldHollywood #Knownforhistemper #JohnGuillermin John Guillermin: The Man, The Myth, The Movies by Mary Guillermin PellinInstitute.com Download the transcript here        

Stephanie Culler PhD, Co-Founder and CEO, Persephone Biosciences describes how the microbiome, the microbes that exist in our GI tract, impacts our overall health and specifically the immune system. Their goal is to leverage the impact of a healthy microbiome to improve the effectiveness of drugs and vaccines. By creating the VOICES study, Persephone is looking at a representative population to look at the connection between the microbiome and clearance of viral infections as well as vaccine efficacy to better understand how the microbiome is impacting a patient's response to the COVID-19 vaccines.  @persephonebio #GutMicrobiome #Microbiome #COVID19 #vaccine PersephoneBiosciences.com Download the transcript here

Maria Maccecchini PhD, Founder, President, CEO, Annovis Bio has been on the path to find a way to protect nerve cells to maintain overall health. Lead therapy ANVS401 (phase 2) is designed to treat Alzheimer's, Parkinson's and other neurodegenerative diseases by tapping into the brain's defense mechanism to get rid of toxic proteins that impair axonal transport, the body's information highway. Affecting the manufacture of amyloid, tau and alpha-synuclein, the treatment is lowering inflammation and showing statistical improvement in function. #Alzheimers #Parkinsons #axonaltransport Annovisbio.com Download the transcript here

Usama Malik, CEO, Fore Biotherapeutics is aiming to treat patients with rare cancer mutations with a hyper targeted precision or personalized approach by using the Fore AI-based technology platform to investigate which drugs might work best for each mutation. While most cancer companies focus only on the most prevalent mutations, Fore is expanding the search by looking at hundreds of mutations to identify driver mutations that actively contribute to the growth of tumors. Fore is in search of unaddressed patient populations and patients where existing therapeutics are not working. #ForeBiotherapeutics #cancer #raredisease #oncology #BRAF #precisionmedicine #personalizedmedicine #DriverMutations Fore.Bio Download the transcript here

Kurt Workman, Co-Founder and CEO, Owlet describes a digital healthcare platform for parents of infants that is part of a connected nursery ecosystem providing critical and reassuring real time and archived data about the baby.  The pulse oximetry technology in their anchor product Smart Sock allows parents to track the baby's heart rate, oxygen levels, information about movement, sleep quality and skin temperature and notifies the parent in real-time if they need to check on the baby. This new source of data about babies, once they have left the hospital and are home, is being used by researchers to study infant cardiac issues and high risk as well as presumably healthy babies. @owletbabycare #newparent #newdad #newmom #baby #babyregistry #sleeptraining #digitalhealth OwletCare.com Download the transcript here

Luke Smith, Client Operations Analyst, Central Logic and the Director of the Arizona Surge Line finally has time to reflect on the work that went into managing access to hospitals and post-acute care for patients suffering from COVID-10 throughout the state of Arizona, at one point the number 1 hot spot in the world for positivity.  The Surge Line Access Center worked with public and private organizations to expeditiously transfer patients from a diverse population to the level of care they needed as well as get them back home safely. @CentralLogic #HealthSystems #PatientOutcomes #HealthIT #PublicHealth #Arizona #COVID19 #RevenueCapture #ClinicianEffectiveness #Hospitals #BedVisibility #PatientExperience CentralLogic.com Download the transcript here.

Amy Grover, Director of Patient Advocacy, Catalyst Pharmaceuticals works primarily with patients suffering from Lambert-Eaton Myasthenic Syndrome LEMS an ultra-rare disease which is very similar to a larger rare disease myasthenia gravis MG. Working with the patient community and patient advocacy groups, Catalyst is providing support, tools and resources that for the most part have moved online during the pandemic.  As a seasoned patient advocate, Amy is aware of how unique each patient's journey is and how important their participation is in driving research. @CatalystForRare #RareReason #rarediseases #LEMS #MG #patientadvocate CatalystPharma.com Download the transcript

Sally Embrey, Vice President Public Health and Health Tech, DataRobot is applying knowledge from work as an enterprise AI company to attacking the problem of containing and defeating COVID-19. ContagionNET was created to identify leading and lagging indicators of the next COVID-19 hotspot and to help people understand their status, risk and ability to spread the disease. Combining science, testing data and AI-based technology, models have been created and used by NIH, HHS, FDA and other partners to better allocate resources, recruit for vaccine trials, and make more accurate long-term forecasts. @ContagionNET #DataRobot #COVID19 #pandemic #NIH #PopulationHealth #AI #VaccineTrials #COVIDHotSpots DataRobot.com Download the transcript here