Empowered Patient Podcast

David Arthur, CEO, Salarius Pharmaceuticals explains the role of our epigenome and what happens when someone is suffering from an epigenetic illness such as Ewing's sarcoma.  A whole series of cancers can trace their cause back to the body misreading genes and that leads to dysregulation of genetic expression. With few options to treat Ewing's sarcoma, a rare orphan pediatric disease, Salarius is testing a new treatment that can provide hope to patients by inhibiting the LSD1 enzyme and effectively addressing the dysregulation. @salariuspharma #ewingsarcoma #ewingssarcoma #rarediseases Salariuspharma.com Download the transcript here  

Dr. Andrea Madrigrano is a general surgeon with an expertise in breast cancer at Rush University Medical Center in Chicago.  She shares her concern about the high rate of re-excision, the need for a second operation, after a lumpectomy to save the breast with early-stage cancer.  Dr. Madrigrano discusses how the Kubtec Mozart 3D tomosynthesis unit allows surgeons to make more informed decisions in near real time cutting re-excision rates in half. #breastcancer #cancer #KubtecMozart #lumpectomy @madrigrano_am Download the transcript here

Tim Moran, CEO, Motus GI talks about their focus on endoscopy solutions that improve clinical outcomes for patients facing a critical colonoscopy while in the hospital.  The Pure-Vu system developed by Motus GI is a disposable sleeve that fits on the top of their reusable scope to allow irrigation and suction evacuation.  This enhancement can save time by eliminating delays in conducting the colonoscopy as well as reducing costs and need for additional time in the hospital. @Motus_GI #colonoscopy MotusGI.com Download the transcript here

Greg Merril, CEO, Adaptive Phage Therapeutics describes useful viruses that host on and kill bacteria acting as nature's natural antibiotic.  Phage therapy actually predates antibiotics but recent research has enabled scientist to better identify which phage will have the desired impact on specific bacteria.  Greg talks about how modern phage therapy, drawing on a large collection of phage, might become the best way to treat recalcitrant, chronic infections where antibiotics have failed.  Greg's father Carl Merril spent the majority of his career at NIH working on basic research on phage beginning in the mid 1960s. #phagetherapy #phage #antibiotics #viruses APhage.com Download the transcript here.

Dr. Hartmut Ehrlich, CEO, Abivax  gives an update of the French biotech's phase-2b clinical trial drug candidate ABX464 which has shown impressive results.  Dr. Ehrlich discusses how this revolutionary small molecule for oral administration has shown strong anti-inflammatory effects to solve the unmet needs of patients with inflammatory conditions like ulcerative colitis, Crohn's disease, and arthritis by using the body's own immune system to fight the diseases. @abivax #abivax  #inflammation #IBD #rheum Abivax.com Download the transcript here

Michelle Sexton Naturopathic Doctor is an assistant adjunct professor in the department of anesthesiology in the UCSD health system.  She also has a clinical naturopathic and holistic practice working with patients who are looking to understand the underlying cause of disease and to treat the cause rather than the symptom.  Drawing on her understanding of the endocannabinoid system, Michelle explains how THC, the primary compound of cannabis, can be effective for treating pain, seizures, and opioid addiction. #cannabis #endocannabinoid #painmanagement MSextonND.com Download the transcript here  

Jeff Wolf, CEO, Heat Biologics describes the vaccine platform Heat has developed originally for oncology and their licensing agreement with the University of Miami to use the same vaccine approach for NIH-funded studies against Zika, malaria, and HIV against the Coronavirus.  Their novel approach is using allogeneic off-the-shelf contained cell based therapy that delivers a potent cell protein called GP96 that secretes antigens to activate T cells to attack the virus. #Coronavirus #COVID19 HeatBio.com Download the transcript here

Jovan Stevovic, founder, Chino.io provides a window into the challenges of protecting health data, how the European Union is handling security and privacy of healthcare data, and the high standards set by the new GDPR regulation.  Jovan also addresses the need by researchers for population health data, why the European insurance companies are mandated to provide insurance to everyone and the need to educate all stakeholders involved in healthcare and health to protect against inside and outside invasion. @chino_API Chino.io Download the transcript here  

Monique Elwell, COO and Co-Founder, Storyvine shares insights about how big and small pharma, medical device developers, healthcare providers, health insurance companies and non-profits are using this guided video tool to capture authentic stories from patients which can then be used in telling a broader view of personal experiences.  Monique talks about how patients are being encouraged to share intimate, vulnerable moments to help educate researchers as well as those facing similar health challenges. @StoryvineInc Storyvine.com Download the transcript here

Dr. Yair Saperstein, co-founder and CEO, avoMD is also chief resident in the department of medicine in the New York City Health and Hospital system.  Yair talks about the innovative online tool avoMD is developing to provide relevant portions of guidelines so that doctors can get specific help with the clinical scenario at hand. Yair also explains they are creating an ecosystem that is editable by doctors and providing a way for best practices in hospitals to be more accessible with the goal of improving success at point of care. @avocadoDOC avoMD.io Download the transcript here.