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Empowered Patient Podcast

Latest episodes

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Apr 2, 2025 • 26min

Comprehensive Substance Use Disorder Treatment For those in the Criminal Justice System with Dr. Traci Sweet Holon Health

Dr. Traci Sweet, Co-Founder and COO of Holon Health has developed an approach to treating substance use disorder that emphasizes integrating physical and behavioral health with an awareness of the impact of social determinants of health. Focusing on serving a marginalized criminal justice population that has struggled to navigate the healthcare system, Holon Health is making treatments accessible with 24/7 digital support and human-to-human interactions. Features of the Vibe app include daily affirmations, lessons, and contingency management. The key is looking forward, not revisiting the past. Traci explains, "We developed Holon Health because so many people struggle with navigating the system, particularly in terms of integrated complete treatment, for so many years now. And I've been a doctor in the field for 31 years. For so many years, we've had such a spidered system where we look at the physical health of a patient, and we look at their behavioral health and SUD needs, and we never come together to look at that in a whole body space. So Holon focuses on fully integrating care between physical health needs, substance use disorder, behavioral health, and the additional social determinants of health. So housing, employment, education. We throw everything we can at the clients. On top of that, the addition of our digital app called Holon Vibe really makes treatment accessible 365 days a year, 24/7." "We serve predominantly folks at the intersection of criminal justice and healthcare. My co-founder is formerly very enmeshed in working with the criminal justice population from his former company. I also have some Department of Corrections in my background as well. This patient has been marginalized in many ways and has found just getting through the system without judgment, without stigma, without having to focus on their shame. Their trauma has found it very difficult to navigate. So we're focused on changing that experience, moving this patient in the direction of preventative care, rewarding pro-social behaviors, and offering support that is kind of like Planet Fitness, just judgment-free. And it's been an amazing experience so far." #HolonHealth #CriminalJusticePopulation #HolisticHealthcare #SDOH #SubstanceUseDisorder holonhealth.com Download the transcript here
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Apr 1, 2025 • 19min

Healthcare Apps Driving Interoperability Real-Time Data Access with John Orosco Red Rover Health

John Orosco, CEO and Co-Founder of Red Rover Health is focused on interoperability in the healthcare industry and the potential impact of AI and automation in streamlining healthcare processes. The emergence of revised industry-wide standards has helped improve integration, but true ease of data sharing remains elusive. An app store approach and real-time data access are the next steps in the evolution of integration methodologies, allowing providers to access the best solutions and integrate them with the core EMR systems. John elaborates, "The app store concept, which goes back to what I was saying when I started in this industry in 1998, was the approach. It was to pick the best solution regardless of the vendor that solves this departmental workflow need and let's implement the best solution. Well, integration with the core electronic medical record system was so tough and so painful and so ugly that pretty much the entire industry shifted to one vendor of record. They were like, we're just going to select one vendor. We're going to forego and give up feature functionality. We know that other solutions are better, but everything will be integrated. So, the entire industry shifts to one vendor. With the advent of APIs and interoperability becoming less painful, that was the right model." "So an app store helps facilitate this notion that any provider, regardless of where you're in the country, should have access to the best solutions that any of these vendors offer. They should be able to integrate it with the medical record. It shouldn't be up to the EMR vendors, let's say, to dictate which solutions do and don't integrate or that their solutions are the only ones that are available. A true app store concept would open the door for all these great solutions that providers would have access to, and they get to decide which ones they want to implement and use." #RedRoverHealth #HealthcareInnovation #HealthTech #Interoperability #DigitalHealth #HealthIT #AIinHealthcare #SeamlessIntegration redrover.health Download the transcript here
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Mar 28, 2025 • 19min

Leveraging AI and Subject Matter Expertise to Tackle Complex Healthcare Claims and Reduce Denials with Mike Esworthy EnableComp

Mike Esworthy, Chief Strategy Officer at EnableComp, understands the challenges that health systems face when dealing with complex health claims such as workers' compensation, Veterans Administration, motor vehicle accidents, Medicaid, and out-of-state claims. These exception-based claims require deep subject matter expertise to identify the right payer and process the claims correctly. Using AI-driven technology, EnableComp helps hospitals manage complex claims, minimize the number of denials, optimize revenue, and allow them to focus on their core commercial claims.  Mike explains, "I think the easiest example to provide in that context, if you look at a worker's comp claim, more often than not, when a patient comes into the hospital, they don’t know who their company's workers' comp provider is, and so often they hand over the commercial insurance card. If that doesn't get caught early, the commercial insurance gets billed, it results in a denial, and the claim sits out there in the ether for 30, 45 days before it comes back to the provider to go figure out who is the right payer class for this. So that's the big picture of the challenges. And then each of those claim types has unique nuances that make this challenging." "I think there are a lot of good things happening in the VA that are, in theory, improving access for veterans, and that's a great thing. From a claim standpoint, though, I think all of the core challenges still remain. And so I know that many of the EMRs have been putting a focus on interoperability, and all of that is great from a treatment care coordination, getting veterans seen in hospitals, and getting them through the door." "But once they've been treated, all of the same challenges that were prevalent before, all of these announcements are still out there. And I think the complexity still exists in terms of not being a normal payer pathway for providers and not knowing all the specific rules. One such example is that you were only allowed one appeal level within the veteran's claims, which means you have to get it right the first time. And so there's a really important component of knowing how to process the claim, getting it done correctly, and ensuring that you're maximizing the yield and the outcome of the claim itself." #EnableComp #VeteranCare #HealthcareInnovation #ComplexRCM  enablecomp.com Download the transcript here
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Mar 27, 2025 • 18min

Expanding Use of Focused Ultrasound as Non-Invasive Treatment for a Wide Range of Indications with Dr. Neal Kassell Focused Ultrasound Foundation

Dr. Neal Kassell, Founder and Chairman of the Focused Ultrasound Foundation,  is working to raise awareness and drive the utilization of focused ultrasound to treat a wide range of medical conditions. This non-invasive technology uses medical imaging to precisely target and treat tissue deep in the body. Focused ultrasound has multiple mechanisms of action and can be used for destroying tumors, modulating neural activity, delivering drugs, and stimulating the immune system. Neal explains, "So focused ultrasound is a new, totally non-invasive therapeutic technology, and it's the intersection of medical imaging, which is either ultrasound or MR imaging, which is used to identify the portion of the body that we want to treat to plan the treatment, and then to guide the treatment. Then, the focused ultrasound technology delivers the energy that treats the tissue. The way it works is analogous to using a magnifying glass to focus beams of light and burn a hole in a leaf." "But at that focal point where all the beams converge, we now understand 30 ways ultrasound can affect tissue. That's in contrast to, for instance, radiation therapy, which is only one mechanism of action. Or a surgical robot, which is one mechanism of action. Focused Ultrasound has at least 30 mechanisms of action, including destroying tissue at that focal point by a variety of mechanisms,  stimulating or blocking neural activity in the brain called neuromodulation, and delivering drugs or other therapeutic agents precisely to a point in the body where they are needed. This increases both the effectiveness and decreases the systemic side effects, stimulates the body's immune response to tumor, and to the effectiveness of cancer immunotherapy agents." "The point in the body where the ultrasound is targeted is, as I said, previously guided and controlled by medical imaging, either ultrasound or MR imaging. Now, the fact that there are so many different mechanisms of action creates the opportunity to treat a wide variety of medical disorders. Today, around the world, there are more than 180 clinical indications or diseases in various stages of research and development in commercialization. Ten years ago or so, there were only three. That's how rapidly the field is growing."  #FocusedUltrasoundFoundation #FUSFoundation #FocusedUltrasound #Glioblastoma #ClinicalTrials #NeuroOncology #Innovation #Healthcare #MedTech #Oncology #Neurology fusfoundation.org Download the transcript here
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Mar 26, 2025 • 22min

Transforming Administration of Biologics from IV Infusions to Subcutaneous At-Home Injections with Bryan Mazlish Surf Bio

Bryan Mazlish is CEO of Surf Bio, a company focused on novel subcutaneous formulations of biologics to enable patients to self-administer these treatments at home. The limitations of subcutaneous administration have historically made time-consuming IV infusions necessary for many biologics. The growing number of biologics and biosimilars in development will further strain the capacity of infusion centers, making subcutaneous administration a way to increase access, reduce healthcare costs, and improve patient adherence. Bryan explains, "Surf Bio is focused on enhancing the ability for patients to take a lot of the innovative and novel biologics that are currently on the market and in development. The vast majority of these historically have required a trip to the infusion center at the hospital, which is quite burdensome and takes a lot of time and resources from the patients and the healthcare system. We focus on creating novel formulations of those same drugs. These biologics can be self-administered at home in seconds instead of requiring a patient to spend the better part of the day commuting to and from an infusion center and sitting in a chair." "When you formulate biologics, they typically are formulated in water and concentrated to very high levels. They become extremely viscous and, consequently, not injectable. So, the ability to inject very high-concentration biologics subcutaneously is limited by the volume that can be administered and the concentration of the biologic that can be squeezed into that volume. As a consequence of this, historically, a large quantity of drug has been diluted at great levels and then dripped into your bloodstream through the intravenous route, which can typically take an hour or, in some cases, multiple hours." #SurfBio #BiologicsDelivery #SubcutaneousInnovation #HealthcareEfficiency surf.bio Download the transcript here
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Mar 25, 2025 • 19min

Simplifying the Healthcare Model to Cut Costs and Improve Access with Mark Newman Nomi Health

Mark Newman, CEO of Nomi Health, focuses on building an operating system for self-insured healthcare to lower costs, remove friction, and simplify the transaction process for employers and providers. Nomi emphasizes holistic preventative healthcare by eliminating barriers like deductibles and copays to encourage the utilization of primary care, mental health, and other services.  The company leverages technology, AI, and asynchronous care to improve access to diverse communities, including Spanish-speaking and low-income workers. Mark explains, "Our model, starting from scratch and starting from a blank sheet of paper, is focused on getting providers out of the collection business so they can focus on the care business. Simplifying the entire transaction of buying and paying for healthcare has been a revolutionary way for our customers to cut their healthcare costs by 20% to 30%. And someday, I think we can hit 50%." "Last time I checked the cost curve in American healthcare has not slowed down and has done nothing but accelerate. So, in my book, I think value-based care has pretty much failed and has been more of a pipe dream versus reality. Our world is how do we take the same doctors, same care and cut 25% of the cost out of it by removing all the friction and pain points and ambiguity and noise as it relates to what an employer pays for healthcare and what a provider collects for delivering that healthcare. We're betting on our model and hope for the best on things like value-based care or other models, but we haven't seen the results delivered yet."  #NomiHealth #HealthcareIndustry #HealthInsurance #Healthcare #HealthcareCEO  nomihealth.com Download the transcript here
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Mar 24, 2025 • 17min

Accurate Early Detection and Monitoring of Lymphedema in Breast Cancer Patients with Maureen McBeth ImpediMed

Maureen McBeth, Senior Medical Affairs Liaison for ImpediMed, a company that develops bio-impedance spectroscopy technology for the early detection and monitoring of lymphedema. This swelling, a common side effect of breast cancer surgery, is often overlooked until it impacts the quality of life of the patient. Using this advanced diagnostic technology,  objective data on the risk and progression enables personalized intervention at the mild stage to prevent progression to severe, irreversible stages. Maureen explains, "Breast cancer-related lymphedema is an underappreciated side effect. Most people think that it's not an issue anymore because we do sentinel node biopsy. Still, we know that any time lymph nodes are removed, damaged, or radiated, they can cause problems with the plumbing system in that area of the body. And inflammation starts, and that's the first thing. People don't feel that, but over time, it starts to impact the lymphatic vessels, and those lymphatic vessels don't pump as well, and a fluid buildup starts to occur. Finally, a patient may start to have symptoms like an aching or a fullness, or they notice things don't fit right, and by the time they notice it, they're likely well into stage one lymphedema, which has noticeable symptoms." "And 20 years ago, when we didn't have these methods to detect it early, we often didn't see patients even with that at stage one. We wouldn't see them until the arm got really big and noticeable. If you can imagine, the guidelines said that the arm had to be 10% larger than the other side before we would diagnose it with lymphedema. Imagine your arm being 10% bigger on one side."  "One of the important things about our technology is that it's about a 30-second test. In terms of non-invasive, the patient doesn't feel it. It gives us this L-Dex score, and we can get other things like body composition. And so, at the start of someone's treatment, it can be used not only for surveillance of lymphedema but also for other side effects of cancer treatment." #ImpediMed #EarlyDetectionMatters #LymphedemaAwarenessMonth #Survivorship #SurvivorshipCare #PatientEmpowerment impedimed.com Download the transcript here
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Mar 20, 2025 • 19min

Novel Long-Acting Antipsychotic Prodrug for Schizophrenia with Dr. Sam Clark Terran Biosciences

Dr. Sam Clark, Founder and CEO of Terran Biosciences, is developing a long-acting once-daily formulation of a new class of antipsychotic drugs to treat schizophrenia. The use of a prodrug approach to modify the new drug Cobenfy allows for improved bioavailability and has been shown to have fewer side effects than traditional antipsychotics. This novel class of antipsychotic drugs targets the muscarinic receptor system, which is a different mechanism of action compared to existing treatments.  Sam explains, "Schizophrenia is a very severe disease. It has both hallucinations and delusions. It also has a set of symptoms called negative symptoms, which encompass social withdrawal and symptoms that can resemble depressive symptoms, cognitive dysfunction, and memory issues. So, with this patient population, there are a number of drugs that are approved to treat schizophrenia called antipsychotics. But until now, there hasn't been a new drug approved with a new mechanism. So, all drugs have the same mechanism to treat the disease since the 1950s."  "But we just got, right now in the space, a new drug approved from Bristol Myers. It just got approved, and Cobenfy is the first new mechanism to treat schizophrenia since the 1950s. But there are some downsides to that drug in that it's dosed twice daily as an oral drug, and there's currently no long-acting injectable. And so, twice daily can be difficult for patients with schizophrenia to take. The space is moving towards long-acting injectables, which can last just one injection for several months." "Now, that strategy has been used with other anti-psychotics on the market, such as Invega, to improve their bioavailability and make long-acting forms. So we took that same approach and created the long-acting prodrugs of Cobenfy, which are TerXT, those long-acting prodrugs. We believe that that will enable a once-daily form and a long-acting injectable that can go multiple months from a single injection and thus improve options for patients with schizophrenia."  #TerranBio #Prodrug #Antipsychotic #Schizophrenia #MentalHealth terranbiosciences.com Download the transcript here
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Mar 19, 2025 • 19min

Non-Hallucinogenic Psychedelics to Induce Neuroplasticity in the Treatment of Mental Health Disorders with Joe Tucker Enveric Biosciences

Joe Tucker, CEO of Enveric Biosciences, is developing non-hallucinogenic psychedelic drugs that aim to induce neuroplasticity and beneficial changes in the brains of patients with mental health disorders. The FDA rejected the approval of MDMA for PTSD treatment due to concerns about the inability to run blind trials to separate the placebo effect from the effects of the drug. Enveric addresses the promise of neuroplastic drugs that stimulate the neural connectivity between the prefrontal cortex and amygdala without hallucinations. Joe explains, "And the problem, endemic to hallucinogenic psychedelics, is that there's no question in the patient's mind, in the doctor's mind, in everybody's mind whether or not they got an hallucinogenic agent. And so when everybody knows whether they got it or not, that's what you call functional unblinding. And so the FDA was very concerned about this. They said you must be able to separate the placebo from the actual drug. Until we see data that gives us confidence that you separated it, we can't approve it, even though it looks like a very positive impact for the patients." "We were looking precisely to see if we could remove the hallucination without removing the benefit. So that's the field we're in. What's it being called right now? It's a very, very new field being called the non-hallucinogenic neuroplastogen- neuroplastogen indicating that it induces neuroplasticity, in other words, rewiring of the brain, but does so without inducing hallucination. We saw two challenges coming: How do you separate placebo from non-placebo effect and the treatment?" "Then the idea would be, hopefully, this psychedelic treatment was so impactful, you didn't need to take any other treatment again for a long period of time. And that seems pretty aspirational, honestly, and likely to get in the way of real patient acceptance that you want something which is not so sort of rock your world. Most people don't want that. They like to be able to have a drug that is like, take an aspirin. You take it every day. You don't have a big impact. You can go about your life. You don't really notice it other than you feel better. And that's the idea behind the non-hallucinogenic neuroplastogen. It fits much more in line with what patients are looking for and expecting and doctors, the whole healthcare system. It just makes a lot more sense." #MentalHealth #MentalHealthDisorders #MentalHealthEpidemic #Depression #Anxiety #PTSD #Neuroplastogens #Psychedelics  enveric.com Download the transcript here
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Mar 18, 2025 • 20min

Authenticity and Consistent Messaging Necessary to Build and Maintain a Company’s Reputation with Ray Jordan Putnam Insights

Ray Jordan is the principal at Putnam Insights, a strategic communications and policy consulting firm, and a partner at Echo Research. The core elements of reputation building are consistent across large and small companies. Many companies mistakenly think that a good reputation comes naturally, but building and maintaining a strong reputation requires a clear mission statement and an authentic voice to reinforce the company's message. Ray elaborates, "In particular, when I've worked on reputation matters, including a lot of reputation on companies, smaller companies are more instinctual rather than based on data. The core elements of reputation are still there. What you need to do is build it, what you can do to lose it, and how it adds value to what you're doing. All of those elements are consistent in some respects. Very different situations, but they have much of the same core elements. That's true from the clinical side, the regulatory side, and the patient care side. From the opinion leader side across the spectrum, including reputation communication." "So, to my mind, building it involves first knowing who and what you are and having a clear definition of yourself. The second is acting consistent with that characterization of who and what you are. The third is being seen acting that way, so being visible in those actions. Those are simple steps. They're not easy steps to accomplish, but they're simple. Who you are, how you behave, and whether you behave accordingly and are seen in that behavior."  #CorporateCommunications #LeadershipInHealthcare #CrisisManagement #ESGStrategy #ReputationManagement #HealthcareLeadership  putnaminsights.com echoresearch.com Download the transcript here

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