Jesse Dufton, an elite rock climber who lost his vision, and his climbing partner Molly Thompson share their remarkable journey together. The duo discusses overcoming challenges in rock climbing through innovative communication techniques and the deep trust they've built. Despite Dufton’s deteriorating sight, their love continues to flourish as they navigate the vertical world of climbing. Their inspiring story highlights the resilience of the human spirit and the burgeoning opportunities for blind athletes in adventure sports.

Yasmeen Abutaleb, a seasoned White House reporter, shares insights on Kamala Harris's pivotal CNN interview and its ramifications for the Democratic base. The discussion delves into the evolving political landscape, including a confrontation involving the Trump campaign and Arlington National Cemetery. Yasmeen also addresses how Harris navigates identity and expectations, particularly while distancing from Biden's past. They dissect the effectiveness of recent political interviews and explore Trump’s changing stances on critical issues like abortion.

Daniel Gilbert, an experienced reporter, dives deep into the booming use of ketamine for treating anxiety and depression, especially post-pandemic. He highlights the delicate balance between its therapeutic promises and potential dangers, especially after recent tragedies. The conversation also unpacks the FDA's challenges with ketamine's approval and the rise of telemedicine prescriptions, revealing how these factors affect patient access to treatment. Gilbert provides a nuanced view of the evolving landscape surrounding this controversial drug.

Former President Donald Trump is grappling with a tumultuous campaign in the face of renewed competition from Vice President Kamala Harris, who has now entered the race. They discuss the challenges Trump faces in shifting his campaign strategies amidst political changes. Personal attacks versus critical policy discussions are in focus, and the episode highlights Trump's voter mobilization tactics. The podcast also touches on his frustrations with immigration and the broader implications of recent geopolitical tensions.

Sunita Williams, a seasoned NASA astronaut with multiple spaceflights, and Barry 'Butch' Wilmore, a veteran of several missions, discuss their unexpected eight-month stay on the International Space Station due to thruster failures of the Boeing Starliner. They delve into the partnership dynamics between NASA and commercial firms, the complex challenges of ensuring astronaut safety, and the evolving risks in space exploration. The conversation sheds light on the implications for future missions and the evolving strategies of space travel.

Silvia Foster-Frau, an investigative reporter specializing in education and public health, dives into the alarming issue of lead contamination in school drinking water. She discusses the shocking findings from the East Ramapo Central School District and the grassroots efforts by students and parents advocating for safe water. The conversation highlights the emotional impact on students and the disparities in educational experiences, as well as recent government funding initiatives to combat this crisis. Foster-Frau reveals the urgent need for comprehensive testing and action.

Cleve Wootson, a White House reporter, shares his insights from the Democratic National Convention. He delves into Kamala Harris's pivotal acceptance speech, highlighting her focus on middle-class values and reproductive rights. The conversation touches on her journey to reclaim respect within the party and the use of freedom and patriotism in her messaging. Wootson also reflects on the notable speeches from Michelle and Barack Obama, analyzing their impact and the evolving strategies of the Democratic Party as the campaign progresses.

President Volodymyr Zelensky of Ukraine, known for his leadership during the ongoing conflict, discusses the surprising Ukrainian incursion into Russian territory. Isabelle Khurshudyan, a bureau chief in Kyiv, provides insights into the military strategies behind this bold maneuver. They delve into the impact on Russian soldiers taken captive, Zelensky's military objectives, and the potential ramifications for both nations. The conversation also touches on Putin's restrained response and the shifting dynamics of support for Ukraine amidst these developments.

Muhammad Yunus, a Nobel Peace Prize-winning economist, and Karishma Mehrotra, a South Asia correspondent, discuss the explosive student protests in Bangladesh that led to Prime Minister Sheikh Hasina's resignation. They delve into the students' passionate demands for political reform, the chaos following the government's collapse, and the crucial role of the military in forming an interim government. As Yunus steps into leadership, they question the path toward meaningful change in a politically charged landscape filled with hope and uncertainty.

Elahe Izadi, a co-host focused on political reporting, joins Aaron Blake, a senior political reporter, and Matt Viser, a White House reporter. They discuss Biden's warm reception at the Democratic National Convention as he transitions to supporting Kamala Harris. The conversation explores the complexities of Biden's speech, balancing party appreciation with the need for new leadership. They also touch on the emotional implications of this political shift and the evolving dynamics within the Democratic Party amidst challenges and calls for unity.