High Performance Longevity

Blood work and wearables are reactive and only sometimes show emergency trends. How do you know whether "healthy" lifestyle practices work for you? What if they're actually not compatible with your particular biochemistry, and worsening your health? What if you had a test that could quantify the impact of your supplements, drugs, fitness, sleep, or habits on any outcome? Say disease risk, IQ, healthspan, or athletic performance? Well, it exists. And this week we're diving deep into the science, applications, and buyer's guide to biological age testing. Meet our guest Ryan Smith attended Transylvania University and graduated with a degree in Biochemistry. After finishing all the educational curriculum and passing USMLE Step 1 he decided to leave and open up a pharmacy in the United States that focused on peptide synthesis and formulations for pharmaceutical preparations. That pharmacy, Tailor Made Compounding, became the 4th fastest growing company in healthcare in the US. During that time Ryan invested in several businesses in the functional medicine space. Ryan exited Tailor Made in late 2020. Since then, Ryan has opened many businesses including TruDiagnostic, a company focusing on methylation array-based diagnostics for life extension and preventive healthcare. TruDiagnostic is a CLIA certified lab and health data company focused on serving integrative and functional medicine providers in the United States. TruDiagnostic has a commitment to research with over 30 approved clinical research studies investigating the epigenetic methylation changes of a variety of longevity and health interventions. Since Tru Diagnostic's inception, they have created one of the largest private epigenetic health databases in the world with over 13,000 patients tested and continue to lead the space in epigenetic methylation interpretation and diagnostic prediction. Thank you to our partners Outliyr Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear TruDiagnostic TruAge (use code URBAN to save and see my review https://outliyr.com/best-biological-age-tests#trudiagnostic-epigenetic-biological-age ): get the most accurate quantification of how your lifestyle is impacting your healthspan (I call it my "cellular report card") Key takeaways Epigenetic algorithms can be used to predict the effect of virtually anything (supplements, sleep, habits, exercise, etc), on any outcome (disease risk, human performance) Unlike 23andMe and other DNA tests, epigenetics return actionable and useful results When choosing a epigenetic age testing service, research the: sample type, scale of testing, # of CPGs measured, algorithm used, privacy of your data Many of the most promising healthspan-increasing modalities are plasma related 1 dose of the peptide SS31 is the energy (ATP) equivalent of 6 months of endurance exercise Links Watch it on YouTube: https://youtu.be/r99LCjAcr8U Full episode show notes: https://mindbodypeak.com/47  Connect with Nick on social media Instagram Twitter/X YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

Spermidine may be the hottest anti-aging compound of the last decade, but is it possible that ancient Japanese longevity scrolls alluded to it over a century ago? What other wisdom did these scrolls contain? Thanks to our guest this week, these nearly-forgotten secrets live on. Meet our guest Oxford Healthspan was founded by Leslie Kenny, a Southern California entrepreneur and graduate of both Berkeley and Harvard, whose life was turned upside down when she was diagnosed with lupus and rheumatoid arthritis in her 30s. When her doctors told her lupus had a life expectancy of five years and that RA could only be managed, not cured, she set out to optimize her health as best she could with safe, natural solutions. She went back to school at the Institute for Integrative Nutrition in NYC, became a Bulletproof coach under health pioneer Dave Asprey, and took on health coaching clients worldwide. At the same time, she began helping life science academics at European universities, including Oxford, to raise money for their discoveries. She met a scientist who introduced her to a promising compound called spermidine. The science was compelling – one scientist even called it "an anti-aging vitamin" in a published scientific journal – and it was safe. S till, because it was natural, food-derived, and not a profitable drug, no one was interested in promoting it. Spermidine wasn't available in the US, so she decided to bring it to the US herself. Today, at age 56, Leslie is living proof that we can get better with age, so long as we take responsibility for our health and meet our doctors halfway. Thank you to our partners  Outliyr Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Oxford Healthspan's Primeadine Spermidine: (see my review https://outliyr.com/best-spermidine-supplements-review#Primeadine ): save 10% with code URBAN10 Key takeaways "Eat bitter foods for a sweet life", or Natto, if you can stomach it Spermidine improves 6 of the 9 hallmarks of aging Spermidine potently activates autophagy and benefits the brain, cardiovascular system, immune system, and supports healthy regeneration and repair Wheat germ-based products are best because they contain spermine, spermidine, and putrescine and this trifecta has awesome additional benefits Links Watch it on YouTube: https://youtu.be/V-meG6JlM_Y Full episode show notes: https://mindbodypeak.com/46  Connect with Nick on social media Instagram Twitter/X YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick  

Once you learn to distill complicated science into its essence, you've developed a transferrable process useful to deeply understanding other subjects. Having taught athletes to improve their performance by focusing on recovery, our guest this week became interested in the longevity industry. He began studying cellular renewal and a process called autophagy. Meet our guest Don Moxley is Director of Applied Science and Brand Development at Longevity Labs Inc. in the United States. Dedicated to helping people live vibrant, fulfilling lives at all ages, Moxley draws upon his career as an athlete, a sports scientist, and an instructor to lead and educate on the science of autophagy and longevity. Throughout his life and career, Moxley has applied science to enhancing well-being. A former captain and Big 10 Championship winner with the Ohio State University wrestling team, Don served as the university's first sports scientist. By giving athletes the ability to track their progress in strength, cardiovascular, and resilience training, he helped the wrestling team win a national title and three Big 10 Championships. He has helped athletes achieve two Olympic medals, four World Championships, seven National Championships, and 23 All-Americans. Thank you to our partners Outliyr Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear SpermidineLIFE spermidine (save 15% with code URABN15) Key takeaways The HR monitor is the single most important piece of equipment you can use as a biohacker or athlete You cannot take the aggregation of scientific studies and know it'll work for you. There's too much diversity between individuals Most people spend too much time training at a high intensity, and not enough at lower intensities Links Watch it on YouTube: https://youtu.be/lct_pE72suE Full episode show notes: https://mindbodypeak.com/45  Connect with Nick on social media Instagram Twitter/X YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

The cleanest, pasture-raised, biodynamic, grass-fed, organic food won't do an unhealthy mouth much good. Even before digestion, with every bite, pathogens can enter the bloodstream through infected gums. Increasing permeability of the blood-brain barrier and leading to neuroinflammation. Brushing and flossing are a good start. But our one or two annual trips to the dentist puts us in reactive mode. Holistic health is about prevention, so why should oral care be any different? What my mouth needs will differ from yours. That's where Bristle can help. Meet our guest Brian Maurer started his career in genomics, at the DNA sequencing company Illumina. There he was on the ground floor of the genomics revolution that is taking place in healthcare and beyond. Brian got to work with some of the most cutting-edge scientists and companies innovating in areas like oncology, synthetic biology, CRISPR, and more. He co-founded Bristle a year ago with the mission of leveraging genomics technology to fundamentally change how we understand and practice oral health. Thank you to our partners Outliyr Peak Performance Shop : get exclusive discounts on cutting-edge health, wellness, & performance gear Bristle Health decodes your oral microbiome and personalizes recommendations so you can easily improve your health and proactively fix any issues before the dentist does (using toxic chemicals that cause more issues down the line) Key takeaways 9/10 adults brush their teeth incorrectly 90% of Americans have one or more cavities, and 47% have some form of gum disease (which correlates strongly with systemic disease) Diabetes, heart disease, Alzheimer's, and other forms of neurodegeneration are diseases of inflammation that often begin in the mouth Saliva is a powerful anti-microbial defense that also helps speed up wound healing. It protects your mouth. Mouth breathing and waking up with a dry mouth, and medications with this as a side effect may be more dangerous than realized Links Watch it on YouTube: https://youtu.be/WovBAsYlhBM Full episode show notes: https://mindbodypeak.com/44   Connect with Nick on social media Instagram Twitter/X YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

It's 2022, and you've probably heard of keto/ketosis/ketones. But you don't need to follow any particular diet to experience the profound health and performance benefits of these drinks. On the performance front, we have ketone esters. Used and researched by NASA, the US military, brain health experts, Tour de France cyclists, Olympians and professional athletes in most sports (NFL, NBA, MLB, UFC), and other high-achievers. A new drink called Hard Ketones contains a different kind of ketone (R1,3 Butanediol) notable as an alcohol alternative for social confidence, relaxation, boosting mood, and crushing appetite. Our conversation this week explores how anyone can use these ketone products for greater quality of life. Meet our guest Frank Llosa is a serial entrepreneur with successes across industries, including real estate, photography featured in National Geographic, and pre-dot com startups. After extensive research, 6 years ago Frank founded KetoneAid — the World's 1st Ketone Ester. KetoneAid has supplied 80% of the Tour de France teams. Since starting, he's worked tirelessly to spread information, bust myths, and bring cutting-edge performance supplements to the masses. He sets the bar for affordable quality. In late 2021, he launched Hard Ketones — The World's First Ketogenic and Ethanol-Free Alcohol. Redefining alcohol and shaping the future of the beverage industry. Brought to you by Outliyr Peak Performance Shop : get exclusive discounts on cutting-edge health, wellness, & performance gear Upgrade your brain with the FREE Outliyr Nootropics Mini-Course [] Ketone Esters  for physical performance (code OUTLIYR gets you free shipping) Key takeaways KetoneAid & Frank Llosa are bringing light to the shady and deceptive marketing practices of the ketone esters/salts industry Quantify the effect of your ketone esters or R1,3 with the Oura Ring The cost of ketone esters has fallen from $25,000 per bottle to less than $30 Most to least effective at increasing blood ketone levels: ketones esters, ketone salts, C8 MCT, MCT, coconut oil R1,3 Butanediol is an effective alternative to (ethanol) alcohol that gives you a buzz, supports optimal health, all without a hangover Links Watch it on YouTube: https://youtu.be/supt9l-6ero Full episode show notes: https://mindbodypeak.com/43   Connect with Nick on social media Instagram Twitter/X YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

Do you know all the latest personal development tips, tricks, tools, and modalities, yet haven't applied them to your life? Maybe you're a Type-A, hard-charger, that bangs out work. But perhaps there's an easier path that yields better results. Meet our guest Chris is the CEO and Facilitator at Training Camp for the Soul. He came into this healing work after over a decade in entrepreneurship and coaching. Having done countless programs and reading hundreds of personal development books, Chris kept running into the same challenges showing up in his life. It wasn't until he found Training Camp for the Soul and did the program for himself that he was able to truly transform his life by going deeper. The healing work Chris focuses on is a combination of breath, somatics, energy work, story work, inner-child work, mindset, and other modalities to get deeper into the subconscious and heal at the root. Thank you to our sponsors Outliyr Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Upgrade your brain with the FREE Outliyr Nootropics Mini-Course  Key takeaways You cannot escape your past, and working on it can be extremely high ROI Using Parts Work, IFS, Re-Parenting, Somatics, and other tools to re-program your subconscious When you address your underlying patterns, you won't need quick fixes and hacks Links Watch it on YouTube: https://youtu.be/CArbQqL2bVA Full episode show notes: https://mindbodypeak.com/41  Connect with Nick on social media Instagram Twitter/X YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

Do you ever wonder about the state-of-the-art research currently being conducted behind closed doors? Research so promising, that it's a closely guarded secret. Decades before they're released to the general public, a secretive agency called DARPA designs the tools and technologies pioneering the future. Our guest worked at DARPA, and is seeking to redefine health and wellness. Meet our guest Trung Tran is a former DARPA program manager. Tran earned a BSEE from the US Air Force Academy and an MBA from Wharton- UPENN. While in the Air Force, he was stationed at Fort Meade and Hanscom AFB working under AIA. He developed cryptographic chips and command and control networks that focused on reducing the time between sensor and shooter. He received 4 medals for his work in these areas. He has spent the last 15 years in silicon valley developing products that range from 100G Top of the Rack Switches, 1U Server Blades, and semiconductors including FPGAs, Memory, PHYs, and Framers. He is a former Vice Chairman of the JEDEC Board of Directors where he worked on the development of DDR3 and FBDIMM specifications. His interest included machine learning, data analytics, and non-conventional computer architecture. Thank you to our sponsors Outliyr Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Key takeaways "If you're under constant stress, you burn nutrients faster than if you ran a marathon" "Everyone wants to be Michael Phelps in the Olympics, but not at 5 AM working out as a 10-year old" "Just because you can do something, doesn't mean you should" "If you have the answer to everything, you might not be asking the right questions" Links Watch it on YouTube: https://youtu.be/bKyr-3m4fss Full episode show notes: https://mindbodypeak.com/40  Connect with Nick on social media Instagram Twitter/X YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

Your mind is potentially your greatest asset. But it's malleable. And neuroscience has evolved tremendously. This episode explores how your common everyday choices improve or worsen your brainpower, and most importantly, what you can do today. Meet our guest Kayla Barnes is an entrepreneur and certified brain health coach with a mission to help her clients and community achieve optimal health through science-backed and proven approaches. Barnes has been named one of the top longevity leaders globally and has been featured in Forbes, Thrive Global, Byrdie, BeWell, Biohackers Magazine + more. Barnes studied nutrition and has trained under the renowned brain doctor, Dr. Daniel Amen. Thank you to our sponsors Outliyr Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Key takeaways "If your gut is not operating at optimal capacity, your brain won't either" Everyday toxins predispose us to cognitive decline and disorders How cannabis, booze, and coffee really impact the brain Genes only determine ~10% of your health outcome, epigenetics (lifestyle) matters more * Brain inflammation is linked to countless ailments Stabilizing blood sugar for brain health, less inflammation, & longer healthspan Kayla's favorite nootropic supplements to rapidly activate her brain Links Watch it on YouTube: https://youtu.be/zngdqQWJ3UA Full episode show notes: https://mindbodypeak.com/39  Connect with Nick on social media Instagram Twitter/X YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick

What do mystics, shamans, and healers have in common? They operate on a different level. In this episode, we demystify the pathways accessed by miracle workers, better understand the chakras, explore how to harness special forms of light to improve your health, and overcome dis-ease with the "subtle elements". For a thorough exploration of the science (Quantum and Newtonian) behind the claims, I suggest you pick up her 800+ masterpiece. Meet our guest Cyndi Dale is an internationally renowned author, speaker, intuitive energy healer, and professor of energy medicine. She has authored 28 books on energy healing, spirituality, and intuition, including the bible of energy medicine and winner of four internationally recognized Publisher's Awards, The Subtle Body: An Encyclopedia of Your Energetic Anatomy, and the largest compendium of chakra knowledge ever produced, Llewellyn's Complete Book of Chakras. Her latest release, Energy Healing for Trauma, Stress & Chronic Illness (Llewellyn, July 2020), was voted Best Holistic Book in 2020 by Book Authority and recently won the 2021 COVR Gold Medal Award in the Health & Healing category. With Dana Childs, her next book coming out is Chakras, Food, and You, featuring information she has shared with clients and students for decades about the energy of nutrition. Thank you to our sponsors * Outliyr Peak Performance Shop [https://outliyr.com/shop/?utm_source=mindbodypeak&utm_medium=referral&utm_campaign=podcast&utm_content=episode+]: get exclusive discounts on cutting-edge health, wellness, & performance gear Key takeaways * Life's vital elements (fire, water, earth, air, etc) recognized by virtually every culture throughout history are made of "subtle elements" * Advanced knowledge of and how to decode the information contained within chakras * We can all feel the "vibe" in the air of a tense room, but our bodies cannot process other peoples' energies * How to protect your energy bodies and use these newly understood forms of light to accelerate healing Links * Watch it on YouTube: https://youtu.be/p8HaE5_wjEs * Full episode show notes: mindbodypeak.com/38 [http://mindbodypeak.com/38] Connect with Nick on social media * Instagram [http://instagram.com/mindbodypeakperformance] * Twitter [http://twitter.com/nicholasurban_] * YouTube [http://mindbodypeak.com/youtube-link] * LinkedIn [https://linkedin.com/in/nicholasurban] Easy to support * Subscribe [https://mindbodypeak.com/subscribe] * Leave an Apple Podcast review [https://mindbodypeak.com/rate-podcast/] * Suggest a guest [https://mindbodypeak.com/contact/] Related shows * EP37 - Beginner's Guide to Subtle Energetic Healing [https://mindbodypeak.com/subtle-energy-healing-science-cyndi-dale] Do you have questions, thoughts, or feedback for Cyndi or me? Let me know at mindbodypeak.com/38 [http://mindbodypeak.com/38] and one of us will get back to you! Strap in, enjoy, and be an Outliyr, Nick

There's not much that virtually every ancient culture agreed on. So when you come across a universal concept, take note. That's exactly why we're digging into the now scientifically validated world of subtle energy and the many names it has gone by throughout the ages. Meet our guest Cyndi Dale is an internationally renowned author, speaker, intuitive energy healer, and professor of energy medicine. She has authored 28 books on energy healing, spirituality, and intuition, including the bible of energy medicine and winner of four internationally recognized Publisher's Awards, The Subtle Body: An Encyclopedia of Your Energetic Anatomy, and the largest compendium of chakra knowledge ever produced, Llewellyn's Complete Book of Chakras. Her latest release, Energy Healing for Trauma, Stress & Chronic Illness (Llewellyn, July 2020), was voted Best Holistic Book in 2020 by Book Authority and recently won the 2021 COVR Gold Medal Award in the Health & Healing category. With Dana Childs, her next book coming out is Chakras, Food, and You, featuring information she has shared with clients and students for decades about the energy of nutrition. Thank you to our sponsors Outliyr Peak Performance Shop: get exclusive discounts on cutting-edge health, wellness, & performance gear Key takeaways Called prana, spiritual energy, psychic energy, chi, qi, orgone, subtle energy, kundalini, life force, energy centers, The All — in different parts of the world Prominent scientists who believed in, and openly talked about, the powers of subtle energy Wiping out disease by using the right frequencies Everyone has one of four unique energetic "superpowers" Links Watch it on YouTube: https://youtu.be/wH4OikKXpy4 Full episode show notes: https://mindbodypeak.com/37  Connect with Nick on social media Instagram Twitter/X YouTube LinkedIn Easy ways to support Subscribe Leave an Apple Podcast review Suggest a guest Do you have questions, thoughts, or feedback for us? Let me know in the show notes above and one of us will get back to you! Be an Outliyr, Nick