Rheumnow Podcast

ACR 2022 Daily Recap for Monday, November 14th.

Breakthrough COVID infection in RMD patients treated with Evusheld Dr. Yuz Yusof talks with Dr. Chris Podgorski at ACR22 Convergence. Lung Involvement in VEXAS Dr. Yuz Yusof and Dr. Marta Casal Moura discusses abstract 1569 presented at ACR22 Convergence.  Abstract 1569: Lung Involvement in VEXAS Syndrome Reproductive health in a post-Roe world Dr. Robert Chao discusses abstract 1673 and L09 presented at ACR22 Convergence.  Abstract 1673: Preconceptional NSAID Treatment Exposure Is Associated with a Significantly Longer Time-to-conception in Women with Spondyloarthritis: Analysis of the Prospective GR2 Cohort Abstract L09: Impact on Access to Methotrexate in the Post-Roe Era Stop Ordering Repeat ANAs! Dr. Kathryn Dao reviews abstracts 1278, 0228, and 0058 presented at ACR22 Convergence. Ultrasound in PsA Dr. Arthur Kavanaugh discusses abstract 2206 presented at ACR22 in Philadelphia. Abstract 2206: Understanding Inter-rater Variability in Scoring of Entheseal Lesions: Results from the Diagnostic Ultrasound Enthesitis Tool (DUET) Study What Happens after you stop biologics? Dr. Robert Chao discusses abstract 0427 presented at ACR22 convergence.  Abstract 0427: Recapture Rates with Ixekizumab After Withdrawal of Therapy in Patients with Axial Spondyloarthritis: Results at Week 104 from a Randomized Placebo-controlled Withdrawal Study Which is better for AxSpA? IL-17i or TNFi? Dr. Robert Chao discusses abstract L15 presented at ACR22 Convergence.

Bouncebackability portends increased risk of adverse outcomes in RA Dr. Richard Conway discusses Abstract 2218 at ACR22 Convergence. Abstract 2218: Frailty Is Associated with Serious Infections in Biologic and Targeted-synthetic DMARD Treated Patients with Rheumatoid Arthritis Deucravacitinib in PsA Dr. Arthur Kavanaugh discusses abstract 1598 at ACR22 Convergence in Philadelphia. Abstract 1598: Safety and Efficacy of Deucravacitinib, an Oral, Selective Tyrosine Kinase 2 Inhibitor, in Patients with Psoriatic Arthritis: 52-Week Results from a Randomized Phase 2 Trial Efficacy and Safety Results from BE OPTIMAL in PsA Dr. Arthur Kavanaugh discusses abstract L02 ACR22 Convergence in Philadelphia, PA.  L02: Bimekizumab Treatment in Biologic DMARD-Naïve Patients with Active Psoriatic Arthritis: 52-Week Efficacy and Safety Results from a Phase 3, Randomized, Placebo-Controlled, Active Reference Study Hydroxychloroquine Update from ACR22 Dr. Michelle Petri reviews several abstracts presented at ACR22 Convergence. Abstracts 0343, 0538, 0976, 0983, 0981, 0980 RA: Steroids are bad, again Dr. Richard Conway discusses Abstract 2219 at ACR22 Convergence Abstract 2219: Time-Dependent Evaluation of Glucocorticoid Exposure Duration and Major Adverse Cardiovascular Events in a Cohort of Veterans with Rheumatoid Arthritis Tapering TNFi in nonradiographic AxSpA Dr. Peter Nash at ACR22 Convergence in Philadelphia, PA. Tofacitinib and RA-ILD Dr. Richard Conway discusses Abstract 2251 at ACR22 Convergence.  Abstract 2251: Reduction in Rheumatoid Arthritis-Associated Interstitial Lung Disease Risk in Patients Treated with Tofacitinib Life or Organ Threatening SLE: What To Do? Is There Anything New? Dr. Michelle Petri discusses Abstracts 1651, 1677 at ACR22 Convergence in Philiadelphia, PA.      

Comorbidities in Axial Spondyloarthritis Dr. Antoni Chan discusses Abstract 1609 at ACR22 Convergence. Diffuse alveolar hemorrhage in antiphospholipid syndrome Dr. Eric Dein discusses Abstract 0675 at ACR22 Convergence. Abstract 0675: Clinical Characteristics and Factors Associated with Relapse and Mortality in Diffuse Alveolar Hemorrhage Among Patients with Antiphospholipid Syndrome: A Multi-Center Retrospective Cohort Eosinophilia in systemic JIA patients after exposure to biologics Dr. Bella Mehta discusses Abstract 0872 at ACR22 Convergence. Abstract 0872: Incidence, Risk Factors, and Outcomes of Eosinophilia on IL-1 and IL-6 Inhibitors in Systemic and Non-Systemic Juvenile Idiopathic Arthritis Gender differences in Axial Spondyloarthritis Dr. Antoni Chan covered abstracts 0497 and 1614 at ACR22 Convergence in Philadelphia, PA. Inadequate Dosing of Hydroxychloroquine Leads to Hospitalizations in SLE Dr. Sheila Reyes discusses abstract 1654 at ACR22 Convergence.  Abstract 1654: Hydroxychloroquine Dosing Less Than 5 Mg/kg/day Leads to Increased Hospitalizations for Systemic Lupus Erythematosus Flares Oligoarticular PsA: FOREMOST Study Dr. Peter Nash discusses abstract 1018 at ACR22 Convergence.  Abstract 1018: Characterization of Joint Distribution and Disease Burden in Patients with Early Oligoarticular Psoriatic Arthritis: Results from the Ongoing FOREMOST Study Sensor-engineered glove evaluates hand function in RA Dr. David Liew discusses abstract 0904 at ACR22 Convergence.  Abstract 0904: Testing the Hand Function with a Sensor-engineered Glove in Patients with Rheumatoid Arthritis

Best of ACR Day Two in PSA Dr. Rachel Tate, discusses abstracts 1018, 1159 at ACR22 Convergence. Comorbidities in Ankylosing Spondylitis Dr. Akhil Sood discusses Abstract 1609 at ACR22 Convergence. Fat and bone are never alone: osteoporotic fracture in RA Dr. David Liew discusses Abstract 889 at ACR22 Convergence.  Abstract 889: Serum Adipokines Predict Incident Osteoporotic Fracture in Patients with Rheumatoid Arthritis GCA: What we feel and what we can't Dr David Liew discusses Abstracts 0483 and 0486 at ACR22 Convergence. Hydroxychloroquine: Cumulative Doses and Thresholds Dr. Sheila Reyes discusses Abstracts 0982 and 0344 at ACR22 Convergence. JAK inhibitors in rheumatic diseases Dr. Antoni Chan discusses abstracts 0510 and 0404 at ACR22 Convergence in Philadelphia, PA. Abstract 0510: MACE and VTE Across Upadacitinib Clinical Trial Programs in Rheumatoid Arthritis, Psoriatic Arthritis, and Ankylosing Spondylitis Abstract 0404: Site-Specific Responses of Joint and Entheses to Tofacitinib in Patients with Ankylosing Spondylitis: A Post Hoc Analysis of a Phase 3 Trial Low-grade Proteinuria in Non-Renal Lupus: Should We be Worried? Dr. Yuz Yusof discusses Abstract 1463 presented at ACR22 Convergence in Philadelphia, PA. PET CT Imaging to Define Risk of Progression from PSO to PsA Dr. Peter Nash discusses Abstract 1018 at ACR22 Convergence. Spondyloarthritis: Novel Therapies, Diagnostic Dilemmas and Depression Dr. Lianne Gensler discusses the following abstracts presented at ACR22 Convergence.  Abstracts 1597, 1598, 1599 (treatment) and 1613, 1609 and 1614 (diagnosis and outcomes) Tapering TNF Inhib in non Radiolgraphic AxSpA Dr. Peter Nash, Philadelphia Vaccines Work! Dr. Eric Dein and Dr. Caoilfhionn Connolly discuss abstracts 2275 & 0797 at ACR22 Convergence.

Join RheumNow faculty to recap the best and most interesting data presented at ACR22 in the area of SLE.  Sunday - SLE Panelists: Drs. Kathryn Dao, Bella Mehta, Yuzaiful Yusof, Eric Dein, Michael Putman, Sheila Reyes, Janet Pope

ACR 2022 Daily Recap for Sunday, November 13th.

AI Future of Sacroiliitis Assessment Dr. Rachel Tate speaks with Dr. Fabian Proft about Abstract 0383 at ACR22 Convergence. Can I stop Methotrexate in RA? Dr. Janet Pope and Dr. Charis Meng discuss Abstract 0916 at ACR22 Convergence.  Abstract 0916: Should RA Patients with Controlled Disease Taper Methotrexate from Targeted Therapy or Continue It? Risk Differences in Sustaining Remission from a Systematic Review and Meta-analysis CAR-T Therapies in Antiphospholipid Antibody Syndrome Dr. Michael Putman and Dr.  Maximilian Konig discuss abstract 1677 at ACR22 Convergence.  Abstract 1677: Chimeric Autoantigen-T Cell Receptor (CATCR)-T Cell Therapies to Selectively Target Autoreactive B Cells Copays Reduce Adherence to SLE Medications Dr. Michael Putman reports on abstract 1115 at ACR22 Convergence in Philadelphia, PA. Copays Reduce Adherence to SLE Medications Dr. Michael Putman reports on abstract 1115 at ACR22 Convergence in Philadelphia, PA. Does Race play a role in Mycophenolate Response in Scleroderma? Dr. Eric Dein speaks with Dr. Lauren Smith about abstract 0521 at ACR22 Convergence in Philadelphia, PA. Abstract 0521: Examination of Differential Response to Treatment with Mycophenolate Mofetil in Black and White Patients with Systemic Sclerosis Fertility issues in SpA Dr. Sheila Reyes speaks with Dr. Sabrina Hamroun about abstract 1673 at ACR22 Convergence.  Abstract 1673: Preconceptional NSAID Treatment Exposure Is Associated with a Significantly Longer Time-to-conception in Women with Spondyloarthritis: Analysis of the Prospective GR2 Cohort Opioid use in PsA and SpA Dr. Eric Dein discusses Abstract 1012 at ACR22 Convergence PsA and SPA: Cyclers, Switchers, Who is the Winner? Dr. Aurelie Najm discusses abstracts 1499 and 1600 at ACR22 Convergence in Philadelphia, PA. Remibrutinib in Sjogren's Syndrome Dr. Michael Putman reports on abstract 1113 presented at ACR22 Convergence meeting in Philadelphia, PA. Abstract 1113: Remibrutinib (LOU064) in Sjögren’s Syndrome: Safety and Efficacy Results from a 24‑Week Placebo-controlled Proof-of-Concept Study      

Advancing Telehealth in Rheumatology Dr. Cush at ACR22 Convergence in Philadelphia, PA. Artificial Intelligence in Detecting Sacroiliitis Dr. Akhil Sood discusses Abstract 0383 at ACR22 Convergence. Abstract 0383: Analysis of the Performance of an Artificial Intelligence Algorithm for the Detection of Radiographic Sacroiliitis in an Independent Cohort of axSpA Patients Including Both Nr-axSpA and r-axSpA COVID Highlights Dr. Leonard Calabrese and Dr. Cassandra Calabrese share highlights on COVID data being presented at ACR22 Convergence. Abstract 0793: Autonomic Nervous System Dysfunction Common Among Patients with Long COVID: An Exploratory Evaluation Abstract L08: Breakthrough Acute COVID-19 Infection During the US Omicron Surge Following Administration of Tixagevimab/Cilgavimab in Immunocompromised Patients with Rheumatologic Disorders Impact of COVID 19 on Pregnancies in Women with RMD Dr. Cassy Sims discusses abstract 0950 at ACR22 Convergence. Abstract 0950: Obstetric Outcomes in Women with Rheumatic Disease and COVID-19 in the Context of Vaccination Status: Data from the COVID-19 Global Rheumatology Alliance Registry Photovoice: A New Visual Research Method in Lupus Dr. Bella Mehta talks with Dr. Candace Feldman about Abstract 1099 at ACR22 Convergence. Abstract 1099: Empowering Patients with Lupus Through Their Photographs: Application of the Photovoice Method to Understand Social Determinants of Health PreRA to Treat or Not! Dr. Janet Pope discusses the Great Debate at ACR22 Convergence in Philadelphia.  Prescribing Methotrexate in Post-Roe Era   Dr. Cassy Sims reports live from ACR22 Convergence in Philadelphia, PA. L09: Impact on Access to Methotrexate in the Post-Roe Era To Switch or Not: Biosimilars in Inflammatory Arthritis Dr. Jonathan Kay reports on abstract 1112 at ACR22 Convergence.   Women vs. Men: Response to Treatment in Seronegative Arthritis Dr. Janet Pope discusses abstracts 1614 and 1601 at ACR22 Convergence in Philadelphia, PA        

Advancing Telehealth in Rheumatology Dr. Cush at ACR22 Convergence in Philadelphia, PA. Artificial Intelligence in Detecting Sacroiliitis Dr. Akhil Sood discusses Abstract 0383 at ACR22 Convergence. Abstract 0383: Analysis of the Performance of an Artificial Intelligence Algorithm for the Detection of Radiographic Sacroiliitis in an Independent Cohort of axSpA Patients Including Both Nr-axSpA and r-axSpA COVID HighlightsDr. Leonard Calabrese and Dr. Cassandra Calabrese share highlights on COVID data being presented at ACR22 Convergence Abstract 0793: Autonomic Nervous System Dysfunction Common Among Patients with Long COVID: An Exploratory Evaluation Abstract L08: Breakthrough Acute COVID-19 Infection During the US Omicron Surge Following Administration of Tixagevimab/Cilgavimab in Immunocompromised Patients with Rheumatologic Disorders Impact of COVID 19 on Pregnancies in Women with RMD Dr. Cassy Sims discusses abstract 0950 at ACR22 Convergence. Abstract 0950: Obstetric Outcomes in Women with Rheumatic Disease and COVID-19 in the Context of Vaccination Status: Data from the COVID-19 Global Rheumatology Alliance Registry Photovoice: A New Visual Research Method in Lupus Dr. Bella Mehta talks with Dr. Candace Feldman about Abstract 1099 at ACR22 Convergence. Abstract 1099: Empowering Patients with Lupus Through Their Photographs: Application of the Photovoice Method to Understand Social Determinants of Health Prescribing Methotrexate in Post-Roe Era Dr. Cassy Sims reports live from ACR22 Convergence in Philadelphia, PA.3 L09: Impact on Access to Methotrexate in the Post-Roe Era Treatment Persistence and Switching Patterns of an Adalimumab Biosimilar Dr. Julian Segan discusses Abstract 1425 at ACR22 Convergence. Abstract 1425: Treatment Persistence and Switching Patterns of ABP 501 (AMGEVITA®) in German Patients with Rheumatic Diseases