Smarter Not Harder

In this episode of the Smarter Not Harder Podcast, our guest Dr. Andrew Gallimore joins our host Dr. Ted Achachoso to give 1 cent solutions to the following $64,000 questions: Does dimethyltryptamine make the brain construct a different reality or does it make the brain perceive a different reality based on the information that it was receiving? How do molecules such as LSD, DMT, psilocybin, and mescaline switch one's reality from one channel to another Why is the fly agaric psychedelic? Dr. Andrew Gallimore is a British neurobiologist, chemist, pharmacologist and writer based in Tokyo, Japan. He has been interested in the relationship between psychedelic drugs, the brain, consciousness, and the structure of reality. He has written a couple of books that he illustrated and self-published. His works are Alien Information Theory: Psychedelic Drug Technologies, and the Cosmic Game (2019), and Reality Switch Technologies: Psychedelics as Tools for the Discovery and Exploration of New Worlds (2022). What we discuss: [00:00] Dr. Andrew Gallimore discusses his self-published book on psychedelic drug technologies and the structure of reality [09:12] DMT and Conway's Game of Life illustrate the emergence of complexity from simple rules [25:29] DMT experience reveals highly intelligent, hyper-dimensional space beyond our reality [34:06] DMT allows the brain to construct an alternate reality without affecting critical parts. [49:36] Salvanorin inhibits the claustrum, which releases the cortex and creates novel emergent patterns of activity. [57:19] Salvia tears apart the fabric of reality while classic psychedelics allow the brain to reach new states [1:12:43] Different drugs affect perception and reality in different ways. [1:20:42] Inhibitory interneurons control excitation inhibition balance [1:36:11] Positive allosteric modulators can enhance receptor activity without the presence of an endogenous agonist. [00:15] Muscimol and its Psychedelic Properties Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more about Dr. Andrew Gallimore: Website: http://alieninsect.net/ Twitter: @alieninsect Instagram: @alieninsect YouTube: youtube.com/c/alieninsect Books: Alien Information Theory: Psychedelic Drug Technologies and the Cosmic Game Reality Switch Technologies: Psychedelics as Tools for the Discovery and Exploration of New Worlds Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder Podcast, our guest Dr. Nasha Winters joins our host Dr. Scott Sherr to give one-cent solutions to life's $64,000 questions within the cancer realm. Dr. Nasha dives into integrative cancer care and opening a metabolic oncology hospital. Dr. Nasha Winters is a global healthcare authority and a best-selling author in integrative cancer care and research. She has educated hundreds of professionals in the clinical use of mistletoe, and created robust educational programs for both healthcare institutions and the public on incorporating vetted integrative therapies and cancer care to enhance outcomes. Dr. Winters is currently focused on opening a comprehensive metabolic oncology hospital and research institute in the United States. What we discussed: [00:00] High insulin levels desensitize cancer cells to radiation [07:20] 10 major drivers to evaluate for each individual's mitochondrial bucket [19:33] A data-driven, individualized approach is key to successful patient outcomes. [25:52] Comprehensive patient history is crucial to evaluate hormone health. [38:23] Gut health plays a significant role in the immune system and cancer therapies [44:46] Individualized treatment is the future of Integrative Oncology. [57:02] Oxidative therapies [1:03:28] Cancer is a manageable disease process, and standard oncology needs to adapt. [1:15:18] Movement towards caring for emotional and mental well-being Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more about Dr. Nasha Winters: Website: https://www.drnasha.com/ Books: https://www.drnasha.com/matcbook/ Facebook: https://www.facebook.com/drnashainc/ LinkedIn: https://www.linkedin.com/in/nasha-winters-796374b6/ Twitter: https://twitter.com/drnashawinters Instagram: @drnashawinters YouTube: https://www.youtube.com/channel/UCn932xLBUY91v9OHE0YuR6A Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder podcast, host Dr. Ted Achacoso is joined by Dr. Anna Lembke who educates us on the opioid epidemic and answered the question: how can a person get addicted to pain? Doctor Anna Lembke is a professor and the medical director of Addiction Medicine at Stanford University School of Medicine, and a New York Times Best Selling author. She received her undergraduate degree in humanities from Yale University and her medical degree from Stanford University. Dr. Lembke is a diplomat for both the American Board of Psychiatry and Neurology, and the American Board of Addiction Medicine. She is also a specialist in the opioid epidemic of the United States. She appeared in the 2020 subcommittee The Social Dilemma. Her works include "How Doctors Were Duped, Patients Got Hooked, and Why It's So Hard to Stop," and the New York Times bestseller "Dopamine Nation: Finding Balance in the Age of Indulgence" which was released in August 2021. What we discuss: 00:00:40 - About Dr. Anna Lembke 00:01:45 - Uncovering co-occurring addictions alongside subsctance abbuse 00:03:46 - Uncovering substance addictions with behavioral-addicted patients 00:04:54 - Is it true that people have addictive personalities? 00:08:02 - Decreasing the amount of the addictive substance over time vs. total abstinence immediately 00:13:16 - Statistics on substance addiction 00:18:14 - How dopamine plays into addiction 00:22:23 - The journey to abuse 00:30:08 - How does one get addicted to pain? 00:39:28 - What happens to dopamine once abstinent 00:42:55 - How does opiate induced hyperalgesia happen? 00:46:25 - How does mindfulness help with addiction? 00:52:02 - Is romantic love an addiction? 00:53:48 - Should hard and sudden heartbreak be treated with drugs from sudden dopamine drops? 00:57:42 - Can psychedelics lead to addiction? Can it help in mitigating addiction? 01:00:29 - Smarter not harder advice to parents on how their children can navigate the dopamine nation Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more about Dr. Anna Lembke: Website: https://www.annalembke.com/ Dopamine Nation: https://www.annalembke.com/dopamine-nation Publications: https://www.annalembke.com/selected-publications Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Troscriptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of Smarter Not Harder, host Dr. Scott Sherr is joined by guest Dr. Dave Rabin. Dr. Rabin dives into psychedelics, neuroplasticity, ketamine, and his technology Apollo. He also discusses the parasympathetic and sympathetic nervous system and the balance in creating a safe space for patients when they are going through psychedelic assisted psychotherapy or mental health treatment. Dr. Rabin ends the episode by sharing about his nonprofit organization, his most recent W.H.O. adventures, and his talks on psychedelics and ketamine in underdeveloped nations. Dr. Dave Rabin is a clinical neuroscientist and an M.D. Board certified psychiatrist. He is an M.D. and Ph.D. at the Albany Medical College and specialized in psychiatry with a distinction of research at the Western Psychiatric Institute and clinical at the University of Pittsburgh Medical Center. He is also a health tech entrepreneur. He invented the Apollo and his company, Apollo Neuroscience is creating wearable technology, using touch and simulating touch. Additionally, he co-founded the Board of Medicine and serves as its executive director. Dr. Dave is conducting research on epigenetic regulation of trauma responses and recovery to elucidate the mechanism of psychedelic assisted psychotherapy in the neurobiology of belief. What we discuss: 00:00:40 - About Dr. Dave Rabin 00:05:18 - About psychedelics and neuroplasticity 00:08:36 - Psychedelics and ketamine 00:12:12 - The mechanisms of ketamine 00:20:21 - Opioid receptors with ketamine being dose dependent 00:27:46 - Balancing the sympathetic and parasympathetic nervous systems 00:34:30 - Dr. Rabin approach to training other doctors and practitioners 00:46:47 - How Dr. Rabin treats his patients in a clinical setting 00:55:30 - The Apollo 01:01:16 - What to prioritize in-session and post-session (ketamine) 01:06:14 - The default mode network 01:11:01 - How to handle bad psychedelic experiences Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more about Dr. Dave Rabin: Website: http://apollo.clinic/ | https://apolloneuro.com/ | https://www.boardofmedicine.org/ Podcast: https://www.thepsychedelicreport.com/ Twitter: https://twitter.com/drdavidrabin Instagram: https://www.instagram.com/drdavidrabin/ LinkedIn: https://www.linkedin.com/in/drdavemdphd/ Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Trosciptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder podcast, we are joined by the father of Biohacking, Dave Asprey. He educates us on the laziness principle and how to utilize it to our advantage, exposomics and epigenetics, and if spirituality can be hacked. Dave Asprey is a four-time New York Times bestselling science author, the creator of the Bulletproof Coffee, the founder of the Bulletproof Company, and is also known as "the Father of Biohacking". He attended University of California, Santa Barbara and majored in computer science and later earned his undergraduate degree in computer information systems from California State University, Stanislaus. He then earned his MBA from Wharton. He is also the host of the Webby award-winning podcast "The Human Upgrade with Dave Asprey" and has been featured in different outlets such as Men's Health, Wired, the Joe Rogan Experience, CNN, and more. What we discuss: 00:00:31 - About Dave Asprey 00:05:15 - About Dave's book, "Smarter Not Harder" 00:05:55 - How can laziness make us strong? 00:10:57 - Why the body wants to conserve energy rather than using it 00:12:55 - How does one cheat the spike? 00:19:47 - How does it become an inside job? 00:25:35 - What is exposome and what's glyphosate got to do with it? 00:27:22 - What are lectins and why should we avoid them? 00:34:35 - More about Vitamin D 00:42:42 - Why mitochondria is focused on in his book? 00:45:21 - What are omega six fatty acids and why are they a double edged sword? 00:51:16 - What is PQQ and what does it do? 00:52:25 - Does PQQ affects the ratio of cardiolipins in the mitochondria? 00:53:44 - How does a pulsed EMF affect your energy level and metabolism? 00:56:32 - What is HUSO? 01:00:32 - How do we hack the epigenome and what does the test that measures ones' epigenetic age do? 01:04:54 - Dave's opinion on 3D printed meat 01:05:01 - How did coming to terms with emotions help Dave in his divorce? 01:10:12 - Why is equanimity the highest spiritual target? 01:12:26 - Dave's top 3 Smarter Not Harder hacks to live a happy life 01:14:45 - Dave's take on psychedelics Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast | https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more about Dave Asprey: Website: https://daveasprey.com/ Podcast: https://daveasprey.com/category/podcasts/ Smarter Not Harder by Dave Asprey: https://www.amazon.com/Smarter-Not-Harder-Biohackers-Getting-ebook/dp/B0B399L6KP?ref_=ast_author_dp Other Books: https://daveasprey.com/books/ Twitter: @bulletproofexec Instagram: @dave.asprey LinkedIn: https://www.linkedin.com/in/asprey/ Facebook: https://www.facebook.com/Daveaspreyofficial/ Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Trosciptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

Why should doctors and health care practitioners learn about artificial intelligence? This is one of the main topics we dive into in this episode of the Smarter Not Harder podcast with guest, Karl Friston. Karl John Friston FRS FMedSci FRSB is one of the greatest scientists in history whose work has been cited over 245,000 times. He is a British neuroscientist and theoretician at University College London. He is an authority on brain imaging and theoretical neuroscience, especially the use of physics-inspired statistical methods to model neuroimaging data and other random dynamical systems. Karl gives us one cent solutions for the following $64,000 dollar questions: 1. What does "I am therefore I think" mean in the context of the free energy principle? And, what do psychedelics have to do with it? 2. How does one go about inventing in tools to investigate this connection hypothesis of schizophrenia? 3. Why should doctors and health care practitioners learn about artificial intelligence? If you want to the answers to these questions, hold on tight, we're about to go on an extremely deep dive into these topics! What we discuss: 0:00:43- About Dr. Karl Friston 00:7:22- The disconnection hypothesis of schizophrenia 00:12:07- The challenges of developing tools to investigate the connection hypothesis of schizophrenia 00:24:14 The difficulties of presenting ideas that are ahead of time 00:32:01 How Dr. Karl Friston got involved in the COVID situation 00:45:16 The free energy principle and coacervate droplets 00:59:13 Is biological life necessary for consciousness or is self evidencing enough? 01:09:50 The different theories for explaining the nature of things 01:18:18 The uncertainty of beliefs 01:26:03 What is the REBUS model? 01:33:16 How psychedelics can induce entropy in a controlled way 01:46:37 The definition of Artificial Intelligence 01:51:59 What is the embodied cognition? 01:58:06 Is curiosity necessary for the expression of the free energy principle? 02:14:05 Learning as humans in evolution 02:27:35 The future of machine learning models 02:33:00 What imaging tools need to be developed for the future 02:41:31 What's next for pharmacology 02:51:59 How we should proceed with psychedelic research Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast / https://homehope.org Instagram: @troscriptions | @homehopeorg Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 athttps://www.homehope.org Get 10% Off your Trosciptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of Smarter Not Harder podcast, we are joined by Dr. Nicole Bijlsma. She chats with host Jodi Duval about all things environmental medicine, including why these exposures are so crucial to health, how the environment effects health, what we can do to mitigate these effects, what an environmental exposure history questionnaire is, how to use it in practice, and so much more. Dr. Nicole Bijlsma is a building biologist, bestselling author, Ph.D. candidate and the CEO of the Australian College of Environmental Studies. She has 30 years of experience lecturing at academic institutions and was formerly a naturopath and acupuncturist. She has written extensively for the Body and Soul newspaper in the Herald Sun, has articles published in peer-reviewed journals, and is frequently consulted by the media to discuss mold, electromagnetic fields, and toxic chemicals. She also gives talks about environmental health issues in Australia and abroad. What we discuss: 00:00:22 - How Dr. Nicole entered into the environmental medicine space 00:09:34 - Environmental medicine's effect on people's emotions 00:11:48 - Environmental exposure to EMFs 00: 21:16 - Environmental exposure to molds 00:23:08 - Are we ever going to adapt to these environmental changes? 00:37:48 - What is the difference between living near the forest and near the ocean? 00:43:20 - Environmental exposure to toxic metals 00:47:09 - What is an environmental exposure history questionnaire and how is it used? 00:57:15 - What's next for Dr. Nicole Bijlsma? Find more from Smarter Not Harder: Website: https://troscriptions.com/blogs/podcast / https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more about Dr. Nicole Bijlsma: Website: https://www.buildingbiology.com.au/ Facebook: https://www.facebook.com/nicolebijlsma1 Instagram: https://www.instagram.com/colbijlsma/ Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Trosciptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter Not Harder podcast, we are joined by Dr. Eric Goodman and Coach Jessie Salas. The two join host Dr. Scott Sherr to discuss Dr. Goodman's book "Foundation of Health" and the Endocannabinoid System, the beginnings of the foundation training, cannabis, the importance of activating your parasympathetic and sympathetic nervous systems, and so much more. Dr. Eric Goodman is the creator of Foundation Training and the author of "Foundation", "Foundations of Health", and"True to Form". He graduated from the University of Central Florida with a bachelors in health sciences, Physiology. Under his degree is a chiropractic degree at Southern California University. Coach Jessie Salas has worked with Dr. Goodman as an understudy and partner in growing the world's knowledge on Foundation Training. He is Dr. Goodman's Chief Operating Officer, who first discovered Foundation Training as a means to address injuries sustained on the job. After seeing its impact on his own injuries, Salas led a 17-year career as a firefighter before turning his attention to coaching others through Foundation Training. What we discuss: 00:01:20 - How Eric transitioned from Foundation Training to learn the Endocannabinoid System and how the two came together 00:09:02 - The connection between cannabis and Foundation Training 00:09:29 - How Eric came up with the postures and movements within Foundation Training 00:10:57 - Eric's experience with Cannabis 00:19:37 - The relationship between the Endocannabinoid System and adaptability 00:23:12 - Coach Jesse's experience reprogramming pain 00:32:01 - Breathwork balancing of the autonomic nervous system 00:41:00 - How Foundation Training can help kids with A.D.D. 00:46:26 - Foundation Training combined with heat and sauna 00:49:31 - The Benefits of traditional and infrared saunas 00:58:16 - Creatin a path that is more optimal for your own health 01:02:49 - What's next for Foundation Training? Find more from Smarter, Not Harder: Website: https://troscriptions.com/blogs/podcast / https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more about Dr Eric Goodman: Website: https://www.foundationtraining.com/ App / Website: https://www.ftstreaming.com/ Instagram: https://www.instagram.com/ericgoodmanft/ Books: https://www.amazon.com/stores/author/B004QTY548/allbooks?ingress=0&visitId=85f396d7-e879-47c5-a74b-7127402543c4&store_ref=ap_rdr&ref_=ap_rdr Find out more about Coach Jessie Salas: Instagram: https://www.instagram.com/coachjsalas/ Website: https://linktr.ee/coachjsalas?utm_source=linktree_profile_share&ltsid=63b60899-426e-431e-bbe6-7c81d26438d2 Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Trosciptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode of the Smarter, Not Harder podcast, we are joined by Adam Robinson. Adam was one of the two co-founders of the Princeton Review and for the last 12 years has been immersed in global financial markets. His book "Cracking the System: The SAT" remains the only test prep book to ever become a New York Times Best Seller." Adam chats with host Boomer Anderson about his unique approach to spot trends before they actually happen, how to simplify financial markets, his experience at the Princeton Review, his definition of struggle, the role of mentors, and so much more. What we discuss: 00:00:15 - About Adam Robinson 00:02:39 - What are the indicators that help determine the status of the world in the world market today? 00:15:38 - Adam's process for simplifying relatively complex subjects 00:29:15 - Adam's systems for discerning relatively complex topics 00:36:14 - What allows Adam to see clearly as an "idea architect" 00:43:51 - Adam's Bayesian Approach for adjusting based on feedback 01:03:03 - Adam's take on how children should look at struggles 01:14:57 - How important is it to tighten the feedback loop versus having a longer feedback loop 01:16:09 - The common thread amongst all of Adam's mentors 01:24:39 - Adam's advice for people that are jack of all trades 01:35:38 - How Adam sets up his routines 01:49:22 - Adam's concerns about humans in today's world 01:53:04 - How we can fundamentally change the way people look at the world 02:06:32 - Exciting news about Adam Robinson's upcoming book releases! Find more from Smarter, Not Harder: Website: https://troscriptions.com/blogs/podcast / https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more about Adam Robinson: Website: https://iamadamrobinson.com/ Twitter: https://twitter.com/IAmAdamRobinson Instagram: https://www.instagram.com/iamadamrobinson/ LinkedIn: https://www.linkedin.com/in/adam-robinson-49158b1/ Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Trosciptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.

In this episode, we are joined Dr. Dominic D'Agostino, Ph.D. He is an Associate Professor with tenure at the University of South Florida where he teaches students of the Morsani College of Medicine and the Department of Molecular Pharmacology and Physiology, with a focus on such topics as neuropharmacology, medical biochemistry, physiology, neuroscience, and neuropharmacology. He is also a Research Scientist at the Institute for Human and Machine Cognition(IHMC) to assist with their efforts towards optimizing the safety, health and resilience of the warfighter and astronaut. Dr. D'Agostino chats with host Dr. Scott Sherr on manta rays being ketogenic, his early research in the field of oxidative stress, ketones in cancer, ketones and its effect on mitochondrial function, ketones and epigenetics, and so much more. What we discussed: 00:00:22 - Introduction 00:02:12 - Manta Rays are ketogenic 00:03:54 - Is it common for fish to use ketones as fuel? 00:05:22 - How Dr. D'Agostino got into the ketogenic diet 00:08:49 - Oxidative stress 00:09:49 - Ketones in cancer 00:13:12 - The ketogenic diet 00:14:56 - The protein sparing modified ketogenic diet 00:16:24 - How Dr. D'Agostino got involved in the optimal performance world 00:19:53 - Ketones and its effects on mitochondial function 00:27:11 - Ketones and Epigenetics 00:30:43 - Dr. D'Agostino's thoughts on ketones over the years 00:34:02 - The mechanism of a ketone induced increase in insulin 00:38:18 - Maintaining ketosis for long periods of time 00:45:07 - The Ketogenic diet and neurotransmitters 00:54:16 - Effects of long term ketogenic diets of menstrual cycle 00:56:26 - Ketonegic diet and microbiome 01:01:49 - The best way to keep your glucose from spiking 01:04:11 - Ketogenic diet and endocannabinoid system 01:07:21 - Dr. D'Agostino's exciting project on metabolic psychiatry Find more from Smarter, Not Harder: Website: https://troscriptions.com/blogs/podcast / https://homehope.org Instagram: @troscriptions | @homehopeorg Find out more about Dr. Dominic D'Agostino: Website: https://ketonutrition.org/ Website: https://linktr.ee/Domdagostino Twitter: https://twitter.com/dominicdagosti2 Instagram: https://www.instagram.com/dominic.dagostino.kt/ Get 10% Off Your Purchase of Metabolomics Module by using PODCAST10 at https://www.homehope.org Get 10% Off your Trosciptions purchase by using POD10 at https://www.troscriptions.com Get daily content from the hosts of Smarter Not Harder by following @troscriptions on Instagram.